Research Topics
| S W GuoSummaryAffiliation: University of Minnesota Country: USA Publications
|
Detail Information
Publications
Linkage disequilibrium measures for fine-scale mapping: a comparisonS W Guo
Division of Epidemiology, University of Minnesota, Minneapolis 55454 1015, USA
Hum Hered 47:301-14. 1997..The initial incomplete linkage disequilibrium could render all measures useless. These expected values also show clearly why in Devlin and Risch's simulation some measures performed very badly under certain circumstances...
Estimating the age of mutant disease alleles based on linkage disequilibriumS W Guo
Division of Epidemiology, University of Minnesota, Minneapolis 55454 1015, USA
Hum Hered 47:315-37. 1997..The former data set allows us to trace the origin and dispersion of the most common mutation for cystic fibrosis. The latter provides an opportunity to examine whether all mutations for these diseases have the same age...
Inflation of sibling recurrence-risk ratio, due to ascertainment bias and/or overreportingS W Guo
Institute of Human Genetics, University of Minnesota, Minneapolis, MN 55454 1015, USA
Am J Hum Genet 63:252-8. 1998..This is particularly important if one uses lambdaS for exclusion mapping, for discrimination between different genetic models, and for association studies, since these practices hinge tightly on an accurate estimation of lambdaS...
Threshold distributions of phenylthiocarbamide (PTC) in the Chinese populationS W Guo
Institute of Human Genetics, University of Minnesota, Minneapolis 55454 1015, USA
Ann N Y Acad Sci 855:810-2. 1998..Several authors had previously reported PTC data on Chinese living outside China. Our data are, to our knowledge, the first ever collected from the Chinese population within China...
Modeling the maternal-age dependency of reproductive failure and genetic fitnessC J Zheng
Division of Environmental and Occupational Health, University of Minnesota, Minneapolis 55455, USA
Evol Dev 2:203-7. 2000....
