Shelly Gunn

Summary

Affiliation: University of Texas Health Science Center
Country: USA

Publications

  1. ncbi request reprint Molecular characterization of a patient with central nervous system dysmyelination and cryptic unbalanced translocation between chromosomes 4q and 18q
    Shelly R Gunn
    Department of Cellular and Structural Biology, The University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    Am J Med Genet A 120:127-35. 2003
  2. pmc Use of DNA sequencing analysis to confirm fungemia due to Trichosporon dermatis in a pediatric patient
    Shelly R Gunn
    Department of Pathology, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, Texas 78229, USA
    J Clin Microbiol 44:1175-7. 2006
  3. ncbi request reprint Comparative genomic hybridization arrays in clinical pathology: progress and challenges
    Shelly R Gunn
    Department of Pathology, University of Texas Health Science Center, San Antonio, Texas 78229 3900, USA
    Mol Diagn Ther 11:73-7. 2007
  4. pmc Whole-genome scanning by array comparative genomic hybridization as a clinical tool for risk assessment in chronic lymphocytic leukemia
    Shelly R Gunn
    The University of Texas Health Science Center at San Antonio, Department of Pathology, Mail Code 7750, 7703 Floyd Curl Dr, San Antonio, TX, USA
    J Mol Diagn 10:442-51. 2008
  5. pmc Clinical array-based karyotyping of breast cancer with equivocal HER2 status resolves gene copy number and reveals chromosome 17 complexity
    Shelly Gunn
    Combimatrix Molecular Diagnostics, 310 Goddard, Irvine, California 92618, USA
    BMC Cancer 10:396. 2010
  6. ncbi request reprint Clinical application of array-based comparative genomic hybridization for the identification of prognostically important genetic alterations in chronic lymphocytic leukemia
    Russell A Higgins
    Department of Pathology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Mol Diagn Ther 12:271-80. 2008
  7. doi request reprint Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare event
    I Tien Yeh
    Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Mod Pathol 22:1169-75. 2009
  8. pmc Molecular cytogenetics as a clinical test for prognostic and predictive biomarkers in newly diagnosed ovarian cancer
    Shelly Gunn
    START Center for Cancer Care, San Antonio, TX, USA
    J Ovarian Res 6:2. 2013
  9. pmc Molecular and clinical characterization of a recurrent cryptic unbalanced t(4q;18q) resulting in an 18q deletion and 4q duplication
    Craig Horbinski
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Am J Med Genet A 146:2898-904. 2008
  10. doi request reprint Array CGH analysis of chronic lymphocytic leukemia reveals frequent cryptic monoallelic and biallelic deletions of chromosome 22q11 that include the PRAME gene
    Shelly R Gunn
    Department of Pathology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    Leuk Res 33:1276-81. 2009

Detail Information

Publications11

  1. ncbi request reprint Molecular characterization of a patient with central nervous system dysmyelination and cryptic unbalanced translocation between chromosomes 4q and 18q
    Shelly R Gunn
    Department of Cellular and Structural Biology, The University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    Am J Med Genet A 120:127-35. 2003
    ....
  2. pmc Use of DNA sequencing analysis to confirm fungemia due to Trichosporon dermatis in a pediatric patient
    Shelly R Gunn
    Department of Pathology, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, Texas 78229, USA
    J Clin Microbiol 44:1175-7. 2006
    ..This is the first reported case of human disease caused by Tricosporon dermatis, an organism recently transferred to the genus Trichosporon from Cryptococcus and now confirmed to be a human pathogen...
  3. ncbi request reprint Comparative genomic hybridization arrays in clinical pathology: progress and challenges
    Shelly R Gunn
    Department of Pathology, University of Texas Health Science Center, San Antonio, Texas 78229 3900, USA
    Mol Diagn Ther 11:73-7. 2007
    ..In this article, we share some of our experiences with diagnostic array CGH and discuss recent progress and challenges involved with the integration of array CGH into clinical laboratory medicine...
  4. pmc Whole-genome scanning by array comparative genomic hybridization as a clinical tool for risk assessment in chronic lymphocytic leukemia
    Shelly R Gunn
    The University of Texas Health Science Center at San Antonio, Department of Pathology, Mail Code 7750, 7703 Floyd Curl Dr, San Antonio, TX, USA
    J Mol Diagn 10:442-51. 2008
    ..5%); 13 hybridizations (4.5%) were discordant because of clonal populations that comprised less than 30% of the sample. Array CGH is a powerful, cost-effective tool for genome-wide risk assessment in the clinical evaluation of CLL...
  5. pmc Clinical array-based karyotyping of breast cancer with equivocal HER2 status resolves gene copy number and reveals chromosome 17 complexity
    Shelly Gunn
    Combimatrix Molecular Diagnostics, 310 Goddard, Irvine, California 92618, USA
    BMC Cancer 10:396. 2010
    ..The recent validation of array-based, molecular karyotyping for clinical oncology testing provides an alternative method for determination of HER2 gene copy number status in cases remaining unresolved by traditional methods...
  6. ncbi request reprint Clinical application of array-based comparative genomic hybridization for the identification of prognostically important genetic alterations in chronic lymphocytic leukemia
    Russell A Higgins
    Department of Pathology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Mol Diagn Ther 12:271-80. 2008
    ....
  7. doi request reprint Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare event
    I Tien Yeh
    Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Mod Pathol 22:1169-75. 2009
    ..We conclude that array comparative genomic hybridization is an accurate and objective DNA-based alternative for clinical evaluation of HER2 gene copy number, and that polysomy 17 is a rare event in breast cancer...
  8. pmc Molecular cytogenetics as a clinical test for prognostic and predictive biomarkers in newly diagnosed ovarian cancer
    Shelly Gunn
    START Center for Cancer Care, San Antonio, TX, USA
    J Ovarian Res 6:2. 2013
    ..In addition, we predicted that the use of a genome-wide copy number analysis (CNA) testing platform would enable us to identify novel potentially targetable chromosomal alterations of therapeutic significance in a percentage of cases...
  9. pmc Molecular and clinical characterization of a recurrent cryptic unbalanced t(4q;18q) resulting in an 18q deletion and 4q duplication
    Craig Horbinski
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Am J Med Genet A 146:2898-904. 2008
    ..Individuals with features suggestive of this 4q;18q translocation but a normal karyotype warrant aCGH or subtelomere studies...
  10. doi request reprint Array CGH analysis of chronic lymphocytic leukemia reveals frequent cryptic monoallelic and biallelic deletions of chromosome 22q11 that include the PRAME gene
    Shelly R Gunn
    Department of Pathology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    Leuk Res 33:1276-81. 2009
    ..Quantitative real-time PCR revealed that ZNF280A, ZNF280B, and PRAME mRNA expression was significantly lower in the 22q11 deletion cases compared to non-deleted cases...
  11. pmc The vanguard has arrived in the clinical laboratory: array-based karyotyping for prognostic markers in chronic lymphocytic leukemia
    Shelly R Gunn
    Combimatrix Molecular Diagnostics, Irvine, CA, USA
    J Mol Diagn 12:144-6. 2010
    ..This Commentary provides a state of the art for array-based karyotyping in cancer diagnostics...