C B Gundersen

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Cysteine string proteins are associated with cortical granules of Xenopus laevis oocytes
    C B Gundersen
    Department of Molecular and Medical Pharmacology and The Crump Institute for Biological Imaging, UCLA School of Medicine, Los Angeles, CA 90095, USA
    Cell Tissue Res 303:211-9. 2001
  2. doi request reprint Synaptotagmins 1 and 2 as mediators of rapid exocytosis at nerve terminals: the dyad hypothesis
    Cameron B Gundersen
    Department of Molecular and Medical Pharmacology, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA
    J Theor Biol 332:149-60. 2013
  3. doi request reprint Cysteine string protein beta is prominently associated with nerve terminals and secretory organelles in mouse brain
    Cameron B Gundersen
    the Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Brain Res 1332:1-11. 2010
  4. ncbi request reprint A Xenopus cysteine string protein with a cysteine residue in the J domain
    A Mastrogiacomo
    Department of Molecular and Medical Pharmacology, UCLA School of Medicine 90095, USA
    Biochim Biophys Acta 1401:239-41. 1998
  5. ncbi request reprint Attenuated influx of calcium ions at nerve endings of csp and shibire mutant Drosophila
    J A Umbach
    Department of Molecular and Medical Pharmacology and The Crump Institute for Biological Imaging, University of California Los Angeles School of Medicine, Los Angeles, California 90095, USA
    J Neurosci 18:3233-40. 1998
  6. ncbi request reprint Intrinsic membrane association of Drosophila cysteine string proteins
    A Mastrogiacomo
    Department of Molecular and Medical Pharmacology and Crump Institute for Biological Imaging, UCLA School of Medicine, Los Angeles, CA 90095, USA
    FEBS Lett 436:85-91. 1998
  7. ncbi request reprint Evidence that cysteine string proteins regulate an early step in the Ca2+-dependent secretion of neurotransmitter at Drosophila neuromuscular junctions
    J A Umbach
    Department of Molecular and Medical Pharmacology and The Crump Institute for Biological Imaging, University of California at Los Angeles School of Medicine, Los Angeles, California 90095, USA
    J Neurosci 17:7203-9. 1997
  8. pmc Electrospray-ionization mass spectrometry of intact intrinsic membrane proteins
    J P Whitelegge
    Center for Molecular and Medical Sciences Mass Spectrometry, Department of Chemistry and Biochemistry, University of California, Los Angeles 90095 1569, USA
    Protein Sci 7:1423-30. 1998
  9. ncbi request reprint The nucleotide and deduced amino acid sequence of a rat cysteine string protein
    A Mastrogiacomo
    Department of Molecular and Medical Pharmacology, UCLA School of Medicine 90024, USA
    Brain Res Mol Brain Res 28:12-8. 1995
  10. ncbi request reprint The DnaJ-like cysteine string protein and exocytotic neurotransmitter release
    E Buchner
    Lehrstuhl fur Genetik, Biozentrum der Universitat, Wurzburg, Germany
    Trends Neurosci 20:223-7. 1997

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Cysteine string proteins are associated with cortical granules of Xenopus laevis oocytes
    C B Gundersen
    Department of Molecular and Medical Pharmacology and The Crump Institute for Biological Imaging, UCLA School of Medicine, Los Angeles, CA 90095, USA
    Cell Tissue Res 303:211-9. 2001
    ..Moreover, because of the relative ease of manipulating cells as large as Xenopus oocytes, this system harbors considerable promise as a model for studying the role of csps and other proteins in exocytotic events...
  2. doi request reprint Synaptotagmins 1 and 2 as mediators of rapid exocytosis at nerve terminals: the dyad hypothesis
    Cameron B Gundersen
    Department of Molecular and Medical Pharmacology, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA
    J Theor Biol 332:149-60. 2013
    ..The relative simplicity of this model and its amenability to empirical testing provide a useful template for future investigations of the molecular events underlying the exocytotic cascade. ..
  3. doi request reprint Cysteine string protein beta is prominently associated with nerve terminals and secretory organelles in mouse brain
    Cameron B Gundersen
    the Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Brain Res 1332:1-11. 2010
    ..Collectively, the enrichment of CSP-beta in synaptosomes and the association of CSP-beta with synaptic vesicles suggest that CSP-beta, like CSP-alpha, may be an important component of the regulated secretory machinery in mouse brain...
  4. ncbi request reprint A Xenopus cysteine string protein with a cysteine residue in the J domain
    A Mastrogiacomo
    Department of Molecular and Medical Pharmacology, UCLA School of Medicine 90095, USA
    Biochim Biophys Acta 1401:239-41. 1998
    ..Xcsp mRNA appears as a 4.6 kb species on Northern analysis, and immunoblot of Xenopus brain membranes reveals a single, 35 kDa Xcsp that can be deacylated, like other csps...
  5. ncbi request reprint Attenuated influx of calcium ions at nerve endings of csp and shibire mutant Drosophila
    J A Umbach
    Department of Molecular and Medical Pharmacology and The Crump Institute for Biological Imaging, University of California Los Angeles School of Medicine, Los Angeles, California 90095, USA
    J Neurosci 18:3233-40. 1998
    ..Thus, using two completely independent Drosophila mutants, we demonstrate that synaptic vesicles and csps are vital for the function of presynaptic Ca channels...
  6. ncbi request reprint Intrinsic membrane association of Drosophila cysteine string proteins
    A Mastrogiacomo
    Department of Molecular and Medical Pharmacology and Crump Institute for Biological Imaging, UCLA School of Medicine, Los Angeles, CA 90095, USA
    FEBS Lett 436:85-91. 1998
    ..Thus, we conclude that under physiological conditions csps are integral membrane proteins of secretory organelles, and that the cysteine string domain plays a vital role in the membrane association of these proteins...
  7. ncbi request reprint Evidence that cysteine string proteins regulate an early step in the Ca2+-dependent secretion of neurotransmitter at Drosophila neuromuscular junctions
    J A Umbach
    Department of Molecular and Medical Pharmacology and The Crump Institute for Biological Imaging, University of California at Los Angeles School of Medicine, Los Angeles, California 90095, USA
    J Neurosci 17:7203-9. 1997
    ..In part, because of previous work showing that csps are important for the functional expression of N-type Ca channels in frog oocytes, we favor the idea that csps participate in a regulatory interaction involving presynaptic Ca channels...
  8. pmc Electrospray-ionization mass spectrometry of intact intrinsic membrane proteins
    J P Whitelegge
    Center for Molecular and Medical Sciences Mass Spectrometry, Department of Chemistry and Biochemistry, University of California, Los Angeles 90095 1569, USA
    Protein Sci 7:1423-30. 1998
    ..The apparent retention of structure by bacteriorhodopsin during the analysis raises the potential of obtaining tertiary structure information using more developed ESI-MS experiments...
  9. ncbi request reprint The nucleotide and deduced amino acid sequence of a rat cysteine string protein
    A Mastrogiacomo
    Department of Molecular and Medical Pharmacology, UCLA School of Medicine 90024, USA
    Brain Res Mol Brain Res 28:12-8. 1995
    ..Moreover, like its Torpedo (fish) counterpart, it is extensively fatty acylated. It will be of considerable interest to ascertain the functional correlates of these cross-species similarities of cysteine string proteins...
  10. ncbi request reprint The DnaJ-like cysteine string protein and exocytotic neurotransmitter release
    E Buchner
    Lehrstuhl fur Genetik, Biozentrum der Universitat, Wurzburg, Germany
    Trends Neurosci 20:223-7. 1997
    ..Here we try to integrate these observations into speculative functional models on the role of this new protein family in synaptic vesicle exocytosis...
  11. ncbi request reprint Absence of junctional glutamate receptor clusters in Drosophila mutants lacking spontaneous transmitter release
    M Saitoe
    Institute for Behavioral Sciences, Gunma University School of Medicine, Maebashi, Gunma 371 8511, Japan
    Science 293:514-7. 2001
    ..Thus, spontaneous vesicle exocytosis appears to be tightly linked to the clustering of glutamate receptors during development...
  12. ncbi request reprint Presynaptic dysfunction in Drosophila csp mutants
    J A Umbach
    Department of Molecular and Medical Pharmacology School of Medicine, University of California, Los Angeles 90024
    Neuron 13:899-907. 1994
    ..This disruption explains the cellular basis of the temperature-sensitive paralysis of these organisms...