D J Gubler

Summary

Affiliation: University of Hawaii
Country: USA

Publications

  1. ncbi request reprint Epidemic dengue/dengue hemorrhagic fever as a public health, social and economic problem in the 21st century
    Duane J Gubler
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Dept of Health and Human Services, PO Box 2087, Fort Collins, CO 80522, USA
    Trends Microbiol 10:100-3. 2002
  2. ncbi request reprint Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses
    John S Mackenzie
    Australian Biosecurity Cooperative Research Centre, Curtin University of Technology, Perth, Western Australia
    Nat Med 10:S98-109. 2004
  3. ncbi request reprint The continuing spread of West Nile virus in the western hemisphere
    Duane J Gubler
    Asia Pacific Institute of Tropical Medicine and Infectious Diseases and Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A Burns School of Medicine, Honolulu, HI 96813, USA
    Clin Infect Dis 45:1039-46. 2007
  4. ncbi request reprint The changing epidemiology of yellow fever and dengue, 1900 to 2003: full circle?
    D J Gubler
    Asia Pacific Institute of Tropical Medicine and Infectious Diseases, John A Burns School of Medicine, University of Hawaii at Manoa, 3675 Kilauea Avenue, Leahi Hospital, Honolulu, HI 96816, USA
    Comp Immunol Microbiol Infect Dis 27:319-30. 2004
  5. pmc Disease ecology and the global emergence of zoonotic pathogens
    Bruce A Wilcox
    Asia Pacific Institute for Tropical Medicine and Infectious Diseases, Department of Tropical Medicine and Medical Microbiology John A Burns School of Medicine, University of Hawaii, 3675 Kilauea Avenue, 96816, Honolulu, HI
    Environ Health Prev Med 10:263-72. 2005
  6. pmc Natural attenuation of dengue virus type-2 after a series of island outbreaks: a retrospective phylogenetic study of events in the South Pacific three decades ago
    Argon Steel
    Department of Tropical Medicine, Medical Microbiology and Pharmacology, Asia Pacific Institute of Tropical Medicine and Infectious Diseases, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96813, USA
    Virology 405:505-12. 2010
  7. ncbi request reprint Molecular evolution of dengue 2 virus in Puerto Rico: positive selection in the viral envelope accompanies clade reintroduction
    Shannon N Bennett
    Department of Biology, University of Puerto Rico Rio Piedras, San Juan, PR, USA
    J Gen Virol 87:885-93. 2006
  8. pmc West Nile virus detection in urine
    Jessica H Tonry
    Asia Pacific Institute of Tropical Medicine and Infectious Diseases John A Burns School of Medicine, Honolulu, Hawaii 96816, USA
    Emerg Infect Dis 11:1294-6. 2005
  9. pmc Epidemic dynamics revealed in dengue evolution
    S N Bennett
    Department of Tropical Medicine, Medical Microbiology and Pharmacology, Asia Pacific Institute of Tropical Medicine and Infectious Diseases, J A Burns School of Medicine, University of Hawaii at Manoa, Hawaii, USA
    Mol Biol Evol 27:811-8. 2010
  10. pmc Dengue fever, Hawaii, 2001-2002
    Paul V Effler
    Disease Outbreak Control Division, Hawaii State Department of Health, Honolulu, Hawaii 96813, USA
    Emerg Infect Dis 11:742-9. 2005

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Epidemic dengue/dengue hemorrhagic fever as a public health, social and economic problem in the 21st century
    Duane J Gubler
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Dept of Health and Human Services, PO Box 2087, Fort Collins, CO 80522, USA
    Trends Microbiol 10:100-3. 2002
    ..Dengue fever/dengue hemorrhagic fever is now one of the most important public health problems in tropical developing countries and also has major economic and societal consequences...
  2. ncbi request reprint Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses
    John S Mackenzie
    Australian Biosecurity Cooperative Research Centre, Curtin University of Technology, Perth, Western Australia
    Nat Med 10:S98-109. 2004
    ....
  3. ncbi request reprint The continuing spread of West Nile virus in the western hemisphere
    Duane J Gubler
    Asia Pacific Institute of Tropical Medicine and Infectious Diseases and Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A Burns School of Medicine, Honolulu, HI 96813, USA
    Clin Infect Dis 45:1039-46. 2007
    ....
  4. ncbi request reprint The changing epidemiology of yellow fever and dengue, 1900 to 2003: full circle?
    D J Gubler
    Asia Pacific Institute of Tropical Medicine and Infectious Diseases, John A Burns School of Medicine, University of Hawaii at Manoa, 3675 Kilauea Avenue, Leahi Hospital, Honolulu, HI 96816, USA
    Comp Immunol Microbiol Infect Dis 27:319-30. 2004
    ..In the last 25 years of the 20th century, however, there was a resurgence of yellow fever in Africa, and of dengue worldwide. The factors responsible for this resurgence are discussed, as are current options for prevention and control...
  5. pmc Disease ecology and the global emergence of zoonotic pathogens
    Bruce A Wilcox
    Asia Pacific Institute for Tropical Medicine and Infectious Diseases, Department of Tropical Medicine and Medical Microbiology John A Burns School of Medicine, University of Hawaii, 3675 Kilauea Avenue, 96816, Honolulu, HI
    Environ Health Prev Med 10:263-72. 2005
    ....
  6. pmc Natural attenuation of dengue virus type-2 after a series of island outbreaks: a retrospective phylogenetic study of events in the South Pacific three decades ago
    Argon Steel
    Department of Tropical Medicine, Medical Microbiology and Pharmacology, Asia Pacific Institute of Tropical Medicine and Infectious Diseases, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96813, USA
    Virology 405:505-12. 2010
    ..Substitutions in the pre-membrane (prM) and nonstructural genes NS2A and NS4A correlated with the attenuation of the Tongan viruses and suggest that genetic change may play a significant role in dengue epidemic severity...
  7. ncbi request reprint Molecular evolution of dengue 2 virus in Puerto Rico: positive selection in the viral envelope accompanies clade reintroduction
    Shannon N Bennett
    Department of Biology, University of Puerto Rico Rio Piedras, San Juan, PR, USA
    J Gen Virol 87:885-93. 2006
    ....
  8. pmc West Nile virus detection in urine
    Jessica H Tonry
    Asia Pacific Institute of Tropical Medicine and Infectious Diseases John A Burns School of Medicine, Honolulu, Hawaii 96816, USA
    Emerg Infect Dis 11:1294-6. 2005
    ..Viral RNA was detected by reverse transcriptase-polymerase chain reaction (RT-PCR). Sequence and phylogenetic analysis confirmed the PCR product to have > or = 99% similarity to the WNV strain NY 2000-crow3356...
  9. pmc Epidemic dynamics revealed in dengue evolution
    S N Bennett
    Department of Tropical Medicine, Medical Microbiology and Pharmacology, Asia Pacific Institute of Tropical Medicine and Infectious Diseases, J A Burns School of Medicine, University of Hawaii at Manoa, Hawaii, USA
    Mol Biol Evol 27:811-8. 2010
    ..Our analysis explicitly integrates epidemiologic and sequence data in a joint model that could be used to further explore transmission models of infectious disease...
  10. pmc Dengue fever, Hawaii, 2001-2002
    Paul V Effler
    Disease Outbreak Control Division, Hawaii State Department of Health, Honolulu, Hawaii 96813, USA
    Emerg Infect Dis 11:742-9. 2005
    ..aegypti were found. This outbreak underscores the importance of maintaining surveillance and control of potential disease vectors even in the absence of an imminent disease threat...
  11. ncbi request reprint Risk factors for infection during a dengue-1 outbreak in Maui, Hawaii, 2001
    John Mosely Hayes
    Dengue Branch, Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1324 Calle Cañada, San Juan, PR 00920 3860
    Trans R Soc Trop Med Hyg 100:559-66. 2006
    ..Our data suggest that ecological characteristics may help Hawaii health officials identify communities at increased risk of dengue infection...
  12. pmc Dengue prevention and 35 years of vector control in Singapore
    Eng Eong Ooi
    Defense Medical and Environmental Research Institute, DSO National Laboratories, Singapore
    Emerg Infect Dis 12:887-93. 2006
    ..Singapore's taking on a leadership role in strengthening disease surveillance and control in Southeast Asia may also be useful in reducing virus importation...
  13. ncbi request reprint Longitudinal studies of West Nile virus infection in avians, Yucatán State, México
    Jose A Farfan-Ale
    Laboratorio de Arbovirologia, Centro de Investigaciones Regionales Dr Hideyo Noguchi, Universidad Autonoma de Yucatan, Merida, Yucatan, Mexico
    Vector Borne Zoonotic Dis 4:3-14. 2004
    ..The brown-crested flycatcher and blue bunting presumably were resident birds; the other WNV seropositive birds were migrants. These data provide evidence of WNV transmission among birds in the Yucatán Peninsula...
  14. ncbi request reprint Cost-effectiveness of a pediatric dengue vaccine
    Donald S Shepard
    Schneider Institute for Health Policy, Heller School, Room G19, Mail Stop 035, Brandeis University, Waltham, MA 02454 9110, USA
    Vaccine 22:1275-80. 2004
    ..Eventually, vaccination may be able to replace environmental control as a strategy for dengue prevention and be cost saving...
  15. ncbi request reprint Serologic evidence of West Nile Virus infection in birds, Tamaulipas State, México
    Ildefonso Fernandez-Salas
    Facultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, San Nicolas de los Garza, Mexico
    Vector Borne Zoonotic Dis 3:209-13. 2003
    ..The WNV-infected birds were all captured in March 2003. These data provide the first indirect evidence of WNV transmission among birds in northern México...
  16. ncbi request reprint Aedes albopictus in Africa
    Duane J Gubler
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522, USA
    Lancet Infect Dis 3:751-2. 2003
  17. pmc West Nile virus transmission in resident birds, Dominican Republic
    Oliver Komar
    Natural History Museum and Biodiversity Research Center, University of Kansas, 1345 Jayhawk Boulevard, Lawrence, KS 66045 7561, USA
    Emerg Infect Dis 9:1299-302. 2003
  18. ncbi request reprint Assessment of dengue risk in relief workers in Puerto Rico after Hurricane Georges, 1998
    Daniel R O'Leary
    Division of Vector Borne Infectious Diseases, National Centers for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80521, USA
    Am J Trop Med Hyg 66:35-9. 2002
    ..The risk of acquiring dengue among relief workers in this study appears low, possibly as a result of protective factors. Travelers to dengue-endemic areas should continue to be advised to protect themselves against mosquito bites...
  19. ncbi request reprint Genetic variation within the premembrane coding region of dengue viruses from the Yucatan peninsula of Mexico
    Francisco J Diaz
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    Am J Trop Med Hyg 67:93-101. 2002
    ..One DEN-2 isolate from 1996 was demonstrated to cluster with viruses of the Sri Lanka genotype, none of which have been detected before in the Americas...
  20. ncbi request reprint Community-based dengue prevention programs in Puerto Rico: impact on knowledge, behavior, and residential mosquito infestation
    Peter J Winch
    Department of International Health, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland 21205 2179, USA
    Am J Trop Med Hyg 67:363-70. 2002
    ..Greater emphasis on the skills necessary for community members to keep containers free of mosquito larvae would increase program effectiveness...
  21. ncbi request reprint Selection-driven evolution of emergent dengue virus
    Shannon N Bennett
    Department of Biology, University of Puerto Rico Rio Piedras, San Juan, Puerto Rico, USA
    Mol Biol Evol 20:1650-8. 2003
    ..Our study therefore demonstrates viral genetic turnover within a focal population and the potential importance of adaptive evolution in viral epidemic expansion...
  22. ncbi request reprint West Nile virus
    Lyle R Petersen
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Public Health Service, Department of Health and Human Services, Fort Collins, Colo, USA
    JAMA 290:524-8. 2003
  23. pmc Emergence and global spread of a dengue serotype 3, subtype III virus
    William B Messer
    University of North Carolina, Chapel Hill, North Carolina, USA
    Emerg Infect Dis 9:800-9. 2003
    ..DENV-3, subtype III isolates from mild and severe disease outbreaks formed genetically distinct groups, which suggests a role for viral genetics in DHF...
  24. ncbi request reprint Guidelines on the cost-effectiveness of larval control programs to reduce dengue transmission in Puerto Rico
    K John McConnell
    Oregon Health and Science University, Department of Emergency Medicine, Portland, Oregon, United States of America
    Rev Panam Salud Publica 14:9-16. 2003
    ....
  25. ncbi request reprint West Nile virus
    Grant L Campbell
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, Department of Health and Human Services, Fort Collins, Colorado, USA
    Lancet Infect Dis 2:519-29. 2002
    ..Serology remains the mainstay of laboratory diagnosis. No WN virus-specific treatment or vaccine is available. Prevention depends on organised, sustained vector mosquito control, and public education...
  26. ncbi request reprint Epidemiology of dengue in Sri Lanka before and after the emergence of epidemic dengue hemorrhagic fever
    William B Messer
    Department of Microbiology and Immunology, University of North Carolina, Chapel Hill 27599, USA
    Am J Trop Med Hyg 66:765-73. 2002
    ..We conclude that an increase in virus transmission or a change in circulating serotypes does not explain the epidemic emergence of DHF in Sri Lanka...
  27. ncbi request reprint Dengue/dengue haemorrhagic fever: history and current status
    Duane J Gubler
    Asia Pacific Institute of Tropical Medicine and Infectious Diseases, John A Burns School of Medicine, University of Hawaii, USA
    Novartis Found Symp 277:3-16; discussion 16-22, 71-3, 251-3. 2006
    ..There are currently no vaccines nor antiviral drugs available for dengue viruses; the only effective way to prevent epidemic DF/DHF is to control the mosquito vector, Aedes aegypti...
  28. ncbi request reprint The global emergence/resurgence of arboviral diseases as public health problems
    Duane J Gubler
    Department of Health and Human Services, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Fort Collins, CO 80522, USA
    Arch Med Res 33:330-42. 2002
    ....
  29. pmc Development of real-time reverse transcriptase PCR assays to detect and serotype dengue viruses
    Li Jung Chien
    Center for Disease Control Taiwan, Taipei, Taiwan, Republic of China, Fort Collins, CO 80521, USA
    J Clin Microbiol 44:1295-304. 2006
    ..Clinical evaluation by two separate laboratories indicated that the C-prM was more sensitive (100%) than the NS5 (91%) or the 3'NC (91%) protocol...
  30. pmc Serologic evidence of West Nile virus infection in horses, Coahuila State, Mexico
    Bradley J Blitvich
    Colorado State University, Fort Collins, Colorado 80523, USA
    Emerg Infect Dis 9:853-6. 2003
    ..5%) horses. We report the first West Nile virus activity in northern Mexico...
  31. ncbi request reprint West Nile virus: epidemiology and clinical features of an emerging epidemic in the United States
    Edward B Hayes
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
    Annu Rev Med 57:181-94. 2006
    ..This paper reviews new information on the epidemiology and clinical aspects of WNV disease derived from greatly expanded surveillance and research on WNV during the past six years...
  32. ncbi request reprint Yellow fever vaccine. Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2002
    Martin S Cetron
    Division of Global Migration and Quarantine, National Center for Infectious Diseases, CDC, USA
    MMWR Recomm Rep 51:1-11; quiz CE1-4. 2002
    ..cdc.gov/travel/index.htm, and through the website for the Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, CDC, at http://www.cdc.gov/ncidod/ dvbid/yellowfever/index.htm...
  33. pmc Serologic evidence of West Nile virus infection in horses, Yucatan State, Mexico
    Maria A Lorono-Pino
    Colorado State University, Fort Collins, Colorado 80523, USA
    Emerg Infect Dis 9:857-9. 2003
    ..2%) horses and confirmed by plaque reduction neutralization test. We report the first West Nile virus activity in the State of Yucatan...
  34. ncbi request reprint Dengue in Grenada
    Andre Panagos
    Windward Islands Research and Education Foundation, True Blue Campus, St George s, Grenada, West Indies
    Rev Panam Salud Publica 17:225-9. 2005
    ..Dengue fever is endemic in the country of Grenada and is grossly underreported as a source of morbidity. The goal of this study was to assess the status of dengue fever in a representative community in Grenada...
  35. ncbi request reprint Enhancing biosynthesis and secretion of premembrane and envelope proteins by the chimeric plasmid of dengue virus type 2 and Japanese encephalitis virus
    Gwong Jen J Chang
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Service, Post Office Box 2087, Fort Collins, CO 80522, USA
    Virology 306:170-80. 2003
    ..Eleven of twelve 2-day-old neonatal mice, derived from a pCB8D2-2J-2-9-1 immunized female mouse, survived intraperitoneal challenge of DEN-2 New Guinea C virus...
  36. ncbi request reprint Serologic survey of domestic animals for zoonotic arbovirus infections in the Lacandón Forest region of Chiapas, Mexico
    Armando Ulloa
    Centro de Investigacion de Paludismo, Tapachula, Chiapas, Mexico
    Vector Borne Zoonotic Dis 3:3-9. 2003
    ..There was no evidence for transmission of the other viruses (ROC, ILH, EEE, WEE) in the study area...
  37. ncbi request reprint Cities spawn epidemic dengue viruses
    Duane J Gubler
    Nat Med 10:129-30. 2004
  38. pmc Dengue 2 PDK-53 virus as a chimeric carrier for tetravalent dengue vaccine development
    Claire Y H Huang
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Fort Collins, Colorado 80522, USA
    J Virol 77:11436-47. 2003
    ..The results of this study demonstrate that the unique attenuation loci of D2 PDK-53 virus make it an attractive vector for the development of live attenuated flavivirus vaccines...