Research Topics
| Juan E GrunwaldSummaryAffiliation: University of Pennsylvania Country: USA Publications
Research Grants
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Detail Information
Publications
Retinopathy and chronic kidney disease in the Chronic Renal Insufficiency Cohort (CRIC) studyJuan E Grunwald
University of Pennsylvania Medical School, Philadelphia, PA 19104, USA
Arch Ophthalmol 130:1136-44. 2012..To investigate the association between retinopathy and chronic kidney disease...
Association between retinopathy and cardiovascular disease in patients with chronic kidney disease (from the Chronic Renal Insufficiency Cohort [CRIC] Study)Juan E Grunwald
University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
Am J Cardiol 110:246-53. 2012..This would make the assessment of retinal morphology a valuable tool in CKD studies of CVD outcomes...
Prevalence of ocular fundus pathology in patients with chronic kidney diseaseJuan E Grunwald
Department of Ophthamology, University of Pennsylvania Medical School, Philadelphia, Pennsylvania, USA
Clin J Am Soc Nephrol 5:867-73. 2010....
Optic nerve blood flow in glaucoma: effect of systemic hypertensionJ E Grunwald
Department of Ophthalmology, Scheie Eye Institute, School of Medicine, University of Pennsylvania, Philadelphia 19104, USA
Am J Ophthalmol 127:516-22. 1999..To investigate optic nerve head blood flow in patients with glaucoma and to assess the effect of systemic hypertension...
Reduced foveolar choroidal blood flow in eyes with increasing AMD severityJuan E Grunwald
Department of Ophthalmology, Scheie Eye Institute, School of Medicine, University of Pennsylvania, 51 North 39th Street, Philadelphia, PA 19104, USA
Invest Ophthalmol Vis Sci 46:1033-8. 2005..To explore further the choroidal circulatory changes in patients with AMD, the relationship between ChBFlow and fundus features associated with increased risk of choroidal neovascularization (CNV) were investigated...
Effect of sildenafil citrate (Viagra) on retinal blood vessel diameterJuan E Grunwald
Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia, 19104, USA
Am J Ophthalmol 133:809-12. 2002..The present investigation was conducted to evaluate the effect of sildenafil citrate (Viagra, Pfizer Inc., New York, NY) on retinal blood vessel diameter...
Acute effects of sldenafil ctrate (Viagra) on intraocular pressure in open-angle glaucomaJ E Grunwald
Department of Ophthalmology, School of Medicine, Scheie Eye Institute 2689, University of Pennsylvania, 51 North 39th Street, Philadelphia, PA 19104, USA
Am J Ophthalmol 132:872-4. 2001..To assess the acute effects of sildenafil citrate (VIAGRA) on the intraocular pressure (IOP) of patients with chronic open-angle glaucoma...
Effect of sildenafil citrate (Viagra) on the ocular circulationJ E Grunwald
Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Am J Ophthalmol 131:751-5. 2001..The purpose of the present investigation was to evaluate the effect of sildenafil on ocular circulation...
Association of risk factors for choroidal neovascularization in age-related macular degeneration with decreased foveolar choroidal circulationWei Xu
Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania School of Medicine, Philadelphia, USA
Am J Ophthalmol 150:40-47.e2. 2010..To investigate the relationship between known risk factors for age-related macular degeneration (AMD) progression and foveolar choroidal circulation in eyes with nonexudative AMD...
The rate of retinal vessel dilation in severe retinopathy of prematurity requiring treatmentLili Grunwald
Scheie Eye Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Am J Ophthalmol 147:1086-91, 1091.e1-2. 2009..To assess whether the rate of change of retinal vessel diameter can help identify infants at the highest risk for severe retinopathy of prematurity (ROP)...
Description of the Age-Related Eye Disease Study 9-step severity scale applied to participants in the Complications of Age-related Macular Degeneration Prevention TrialGui Shuang Ying
Scheie EyeInstitute, University ofPennsylvania, Philadelphia, PA 19104 3309, USA
Arch Ophthalmol 127:1147-51. 2009..To describe characteristics of the Age-Related Eye Disease Study (AREDS) 9-step severity scale applied to participants in the Complications of Age-related Macular Degeneration Prevention Trial (CAPT)...
Effect of Viagra on the foveolar choroidal circulation of AMD patientsTatyana I Metelitsina
Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, 51 North 39th Street, Philadelphia, PA 19104, USA
Exp Eye Res 81:159-64. 2005..006) and PP (P=0.006) were observed at 30 min after sildenafil. Administration of sildenafil citrate didn't cause any statistically significant changes in the foveolar choroidal circulation of AMD patients...
Effect of viagra on retinal vein diameter in AMD patientsTatyana I Metelitsina
Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, 51 North 39th Street, Philadelphia, PA 19104, USA
Exp Eye Res 83:128-32. 2006..Whether this vasodilatation is associated with changes in retinal blood flow needs to be further investigated...
Foveolar choroidal circulation and choroidal neovascularization in age-related macular degenerationTatyana I Metelitsina
Department of Ophthalmology, Scheie Eye Institute, School of Medicine, University of Pennsylvania, 51 North 39th Street, Philadelphia, PA 19104, USA
Invest Ophthalmol Vis Sci 49:358-63. 2008..To investigate in a longitudinal study whether foveolar choroidal blood flow changes are associated with the development of choroidal neovascularization (CNV) in AMD...
The association between drusen extent and foveolar choroidal blood flow in age-related macular degenerationThomas L Berenberg
Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Retina 32:25-31. 2012..To investigate the relationship between drusen extent and foveolar choroidal blood flow in nonexudative age-related macular degeneration...
Photographic assessment of baseline fundus morphologic features in the Comparison of Age-Related Macular Degeneration Treatments TrialsJuan E Grunwald
Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Ophthalmology 119:1634-41. 2012....
Quantitative analysis of retinal vessel diameter reduction after photocoagulation treatment for retinopathy of prematurityKeegan S Johnson
Scheie Eye Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Am J Ophthalmol 143:1030-2. 2007..To evaluate the feasibility of using semiautomated analysis of digital fundus images to quantify effects of photocoagulation on retinal vessel diameter in retinopathy of prematurity (ROP)...
Characteristics of choroidal neovascularization in the complications of age-related macular degeneration prevention trialMaureen G Maguire
Department of Ophthalmology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 3309, USA
Ophthalmology 115:1468-73, 1473.e1-2. 2008..To describe the characteristics of incident choroidal neovascularization (CNV) in observed and treated eyes in the Complications of Age-related Macular Degeneration Prevention Trial (CAPT)...
Effect of isometric exercise on choroidal blood flow in patients with age-related macular degenerationTatyana I Metelitsina
Department of Ophthalmology, Scheie Eye Institute, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Br J Ophthalmol 94:1629-31. 2010..We compared the regulatory responses induced by isometric exercise in control subjects and patients with age-related macular degeneration (AMD) to investigate choroidal vascular regulation in AMD...
Progression to severe retinopathy predicted by retinal vessel diameter between 31 and 34 weeks of postconception ageMichael P Rabinowitz
Department of Ophthalmology, Scheie Eye Institute University of Pennsylvania, Philadelphia, USA
Arch Ophthalmol 125:1495-500. 2007..To assess the predictive value of early retinal vascular diameter measurements for the development of severe retinopathy of prematurity (ROP) in high-risk preterm infants...
Long-term effect of laser treatment for dry age-related macular degeneration on choroidal hemodynamicsMauricio Figueroa
Department of Ophthalmology, Scheie Eye Institute, School of Medicine, University of Pennsylvania, 51 North 39th Street, Philadelphia, PA 19104, USA
Am J Ophthalmol 141:863-7. 2006..This increase may play a role in the mechanism leading to the disappearance of drusen after photocoagulation. Whether removal of drusen after photocoagulation is beneficial to the patients is not known at this time...
Semiautomated analysis of retinal vessel diameter in retinopathy of prematurity patients with and without plus diseaseKeegan S Johnson
Scheie Eye Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Am J Ophthalmol 143:723-5. 2007..To determine the feasibility of using semiautomated analysis of digital fundus images to quantify the differences in retinal vascular diameter between retinopathy of prematurity (ROP) patients with and without plus disease...
Baseline predictors for one-year visual outcomes with ranibizumab or bevacizumab for neovascular age-related macular degenerationGui Shuang Ying
Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Center for Preventive Ophthalmology and Biostatistics, Department of Ophthalmology, Philadelphia, Pennsylvania 19104, USA
Ophthalmology 120:122-9. 2013..To determine the baseline predictors of visual acuity (VA) outcomes 1 year after treatment with ranibizumab or bevacizumab for neovascular age-related macular degeneration (AMD)...
Foveolar choroidal hemodynamics in proliferative diabetic retinopathyLisa S Schocket
New England Eye Center, USA
Int Ophthalmol 25:89-94. 2004..There was a statistically significant negative correlation between duration of diabetes and Chvel (R = -0.55; p = 0.03). CONCLUSIONS: Our results suggest that Chvol and Chflow are significantly reduced in patients with PDR...
Research Grants
- Retinopathy in Chronic Renal InsufficiencyJuan Grunwald; Fiscal Year: 2007....
- Choroidal circulation in age related macular degenerationJuan Grunwald; Fiscal Year: 2007..In addition, the knowledge gained through this investigation could also help in the identification of patients at risk of developing choroidal neovascularization, thus enabling earlier treatment. ..
- Photograph Reading Center for the Comparison of AMD Treatment TrialsJuan Grunwald; Fiscal Year: 2007....
- Retinopathy in Chronic Renal InsufficiencyJuan Grunwald; Fiscal Year: 2009....
- OCULAR HEMODYNAMICS IN GLAUCOMAJuan Grunwald; Fiscal Year: 2001..If hemodynamic abnormalities are present, then attention can be focused on altering the optic nerve circulation as a means of treating glaucoma. ..
- CHOROIDAL CIRCULATION & AGE RELATED MACULAR DEGENERATIONJuan Grunwald; Fiscal Year: 2004..In addition, the knowledge gained through this investigation could also help in the identification of patients at risk of developing choroidal neovascularization, thus enabling earlier treatment. ..
- Retinopathy in Chronic Renal InsufficiencyJuan E Grunwald; Fiscal Year: 2010....
