Research Topics
| Tanja M GruberSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Assay of Escherichia coli RNA polymerase: sigma-core interactionsTanja M Gruber
Departments of Stomatology and Microbiology and Immunalogy, University of California, San Francisco, California 94143-0512, USA
Methods Enzymol 370:206-12. 2003
Multiple sigma subunits and the partitioning of bacterial transcription spaceTanja M Gruber
Department of Microbiology and Immunology, University of California, Genentech Hall, 600 16th St, San Francisco, San Francisco, California 94143, USA
Annu Rev Microbiol 57:441-66. 2003..We use the sigma repertoire of Escherichia coli, Bacillus subtilis, Streptomyces coelicolor, and cyanobacteria to illustrate the different strategies utilized to organize transcriptional space using multiple sigma factors...
Minimal machinery of RNA polymerase holoenzyme sufficient for promoter meltingBrian A Young
Departments of Stomatology and Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA
Science 303:1382-4. 2004..Our results support the model that capture of nontemplate bases extruded from the DNA helix underlies the melting process...
Views of transcription initiationBrian A Young
Department of Biochemistry and Biophysics, University of California, San Francisco, 94143, USA
Cell 109:417-20. 2002..Recent structural studies reveal the nature of the initiating complex and suggest new ways of accomplishing the processes required for initiation...
A hydrophobic patch on the flap-tip helix of E.coli RNA polymerase mediates sigma(70) region 4 functionKati Geszvain
Department of Genetics, University of Wisconsin Madison, Madison, WI 53706, USA
J Mol Biol 343:569-87. 2004..Our studies failed to detect any role for sigma region 1.1 in establishing or maintaining the flap-sigma region 4 interaction, consistent with recent reports placing sigma region 1.1 in the downstream DNA channel...
Autoregulation of a bacterial sigma factor explored by using segmental isotopic labeling and NMRJulio A Camarero
Laboratory of Synthetic Protein Chemistry, The Rockefeller University, New York, NY 10021, USA
Proc Natl Acad Sci U S A 99:8536-41. 2002..More generally, the present work illustrates the power of segmental isotopic labeling for probing molecular interactions in large proteins by NMR...
The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacteriumJonathan A Eisen
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
Proc Natl Acad Sci U S A 99:9509-14. 2002..tepidum and many Archaeal species...
Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseAElizabeth A Campbell
Laboratory of Molecular Biophysics, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
Mol Cell 11:1067-78. 2003..In combination with a model of the sigma(E) holoenzyme and biochemical data, the structure reveals that RseA functions by sterically occluding the two primary binding determinants on sigma(E) for core RNA polymerase...
Group 3 sigma factors in the marine cyanobacterium Synechococcus sp. strain PCC 7002 are required for growth at low temperatureKaori Inoue-Sakamoto
Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, University Park, PA 16802, USA
J Gen Appl Microbiol 53:89-104. 2007....
