Jonathan D Gruber

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc How repeatable are associations between polymorphisms in achaete-scute and bristle number variation in Drosophila?
    Jonathan D Gruber
    Department of Ecology and Evolutionary Biology, University of California, Irvine, California 92697, USA
    Genetics 175:1987-97. 2007
  2. pmc Cis-regulatory variation is typically polyallelic in Drosophila
    Jonathan D Gruber
    Ecology and Evolutionary Biology, University of California, Irvine, California 92697, USA
    Genetics 181:661-70. 2009
  3. pmc A wing expressed sequence tag resource for Bicyclus anynana butterflies, an evo-devo model
    Patricia Beldade
    Department of Ecology and Evolutionary Biology, University of California at Irvine, Irvine, USA
    BMC Genomics 7:130. 2006
  4. pmc Contrasting properties of gene-specific regulatory, coding, and copy number mutations in Saccharomyces cerevisiae: frequency, effects, and dominance
    Jonathan D Gruber
    Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, USA
    PLoS Genet 8:e1002497. 2012
  5. doi request reprint Allelic expression profiling to dissect genome-wide association study signals
    Jonathan D Gruber
    Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI, USA
    Methods Mol Biol 700:153-70. 2011
  6. ncbi request reprint Common Polymorphisms in the Adiponectin Gene ACDC Are Not Associated With Diabetes in Pima Indians
    Barbora Vozarova de Courten
    Translational Genomics Research Institute, Diabetes Research Unit, NIDDK, NIH, 400 North 5th St, Phoenix, Arizona, USA
    Diabetes 54:284-9. 2005
  7. ncbi request reprint Estimation of single nucleotide polymorphism allele frequency in DNA pools by using Pyrosequencing
    Jonathan D Gruber
    Clinical Diabetes and Nutrition Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases NIH, 4212 North 16th Street, Phoenix, AZ 85016, USA
    Hum Genet 110:395-401. 2002
  8. ncbi request reprint The interleukin-6 (-174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians
    Barbora Vozarova
    Clinical Diabetes and Nutrition Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 4212 North 16th Street, Phoenix, AZ 85016, USA
    Hum Genet 112:409-13. 2003
  9. ncbi request reprint Variants in the interleukin 6 receptor gene are associated with obesity in Pima Indians
    Johanna K Wolford
    Clinical Diabetes and Nutrition Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 4212 North 16th Street, Phoenix, AZ 85016, USA
    Mol Genet Metab 80:338-43. 2003

Collaborators

Detail Information

Publications9

  1. pmc How repeatable are associations between polymorphisms in achaete-scute and bristle number variation in Drosophila?
    Jonathan D Gruber
    Department of Ecology and Evolutionary Biology, University of California, Irvine, California 92697, USA
    Genetics 175:1987-97. 2007
    ..Nevertheless, inconsistent results from the other three panels suggest that the relationship between polymorphic genetic markers and loci contributing to continuous variation is not a simple one...
  2. pmc Cis-regulatory variation is typically polyallelic in Drosophila
    Jonathan D Gruber
    Ecology and Evolutionary Biology, University of California, Irvine, California 92697, USA
    Genetics 181:661-70. 2009
    ..If standing cis-regulatory variation is actually slightly deleterious, the true mutational target size is larger...
  3. pmc A wing expressed sequence tag resource for Bicyclus anynana butterflies, an evo-devo model
    Patricia Beldade
    Department of Ecology and Evolutionary Biology, University of California at Irvine, Irvine, USA
    BMC Genomics 7:130. 2006
    ..Here, we describe an Expression Sequence Tag (EST) project for Bicyclus anynana that has identified the largest available collection to date of expressed genes for any butterfly...
  4. pmc Contrasting properties of gene-specific regulatory, coding, and copy number mutations in Saccharomyces cerevisiae: frequency, effects, and dominance
    Jonathan D Gruber
    Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, USA
    PLoS Genet 8:e1002497. 2012
    ..These differences in the frequency, effects, and dominance among functional classes of mutations might help explain why some types of mutations are found to be segregating within or fixed between species more often than others...
  5. doi request reprint Allelic expression profiling to dissect genome-wide association study signals
    Jonathan D Gruber
    Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI, USA
    Methods Mol Biol 700:153-70. 2011
    ..In addition, AE is also an accessible and economical strategy, as it relies heavily upon standard techniques and equipment likely to be present in any disease-mapping laboratory...
  6. ncbi request reprint Common Polymorphisms in the Adiponectin Gene ACDC Are Not Associated With Diabetes in Pima Indians
    Barbora Vozarova de Courten
    Translational Genomics Research Institute, Diabetes Research Unit, NIDDK, NIH, 400 North 5th St, Phoenix, Arizona, USA
    Diabetes 54:284-9. 2005
    ..Our findings suggest that these common ACDC polymorphisms do not play a major role in susceptibility to obesity or type 2 diabetes in this population...
  7. ncbi request reprint Estimation of single nucleotide polymorphism allele frequency in DNA pools by using Pyrosequencing
    Jonathan D Gruber
    Clinical Diabetes and Nutrition Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases NIH, 4212 North 16th Street, Phoenix, AZ 85016, USA
    Hum Genet 110:395-401. 2002
    ....
  8. ncbi request reprint The interleukin-6 (-174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians
    Barbora Vozarova
    Clinical Diabetes and Nutrition Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 4212 North 16th Street, Phoenix, AZ 85016, USA
    Hum Genet 112:409-13. 2003
    ..001). These findings are consistent with a role for genetic determinants of inflammation in the development of T2DM in both Native Americans and Caucasians...
  9. ncbi request reprint Variants in the interleukin 6 receptor gene are associated with obesity in Pima Indians
    Johanna K Wolford
    Clinical Diabetes and Nutrition Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 4212 North 16th Street, Phoenix, AZ 85016, USA
    Mol Genet Metab 80:338-43. 2003
    ..0+/-7.5]; P=0.02-0.004). Our findings suggest that genetic variants in the IL6R gene may play a role in susceptibility to obesity. Assessment of these SNPs in other populations will be useful to determine the magnitude of obesity risk...