MURRAY E GROSSMAN
Affiliation: University of Pennsylvania
Grossman M, Ash S. Primary progressive aphasia: a review. Neurocase. 2004;10:3-18 pubmed
..Testing hypotheses about finer-grained syndromes such as progressive dysarthria or progressive anomia has important consequences for improving our understanding of language organization and the neural basis for language. ..
Grossman M, Anderson C, Khan A, Avants B, Elman L, McCluskey L. Impaired action knowledge in amyotrophic lateral sclerosis. Neurology. 2008;71:1396-401 pubmed publisher
Grossman M. Primary progressive aphasia: clinicopathological correlations. Nat Rev Neurol. 2010;6:88-97 pubmed publisher
Spotorno N, McMillan C, Rascovsky K, Irwin D, Clark R, Grossman M. Beyond words: Pragmatic inference in behavioral variant of frontotemporal degeneration. Neuropsychologia. 2015;75:556-64 pubmed publisher
Bang J, Lobach I, Lang A, Grossman M, Knopman D, Miller B, et al
. Predicting disease progression in progressive supranuclear palsy in multicenter clinical trials. Parkinsonism Relat Disord. 2016;28:41-48 pubmed publisher
..Multiple clinical, neuropsychological, and volumetric MRI measurements are sensitive to change over one year in PSP and appropriate for use in multicenter clinical trials. ..
Giannini L, Irwin D, McMillan C, Ash S, Rascovsky K, Wolk D, et al
. Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia. Neurology. 2017;88:2276-2284 pubmed publisher
..Quantitative measures of phonologic loop function, combined with modified clinical lvPPA criteria, may help discriminate AD-associated PPA. ..
Cousins K, York C, Bauer L, Grossman M. Cognitive and anatomic double dissociation in the representation of concrete and abstract words in semantic variant and behavioral variant frontotemporal degeneration. Neuropsychologia. 2016;84:244-51 pubmed publisher
..These results support a cognitive and anatomic model of semantic memory organization where abstract and concrete representations are supported by dissociable neuroanatomic substrates. ..
Ash S, Ternes K, Bisbing T, Min N, Moran E, York C, et al
. Dissociation of quantifiers and object nouns in speech in focal neurodegenerative disease. Neuropsychologia. 2016;89:141-152 pubmed publisher
..These findings imply that partially dissociable representations in semantic memory may underlie different segments of the lexicon. ..
Busch J, Martinez Lage M, Ashbridge E, Grossman M, Van Deerlin V, Hu F, et al
. Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain. Acta Neuropathol Commun. 2013;1:36 pubmed publisher
..In addition, we demonstrate that FTLD-TDP cases with GRN mutations exhibit a loss of neuronal TMEM106B subcellular localization, adding to evidence that TMEM106B and progranulin may be pathophysiologically linked in FTLD-TDP. ..