Robert Gross

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. doi request reprint Managed problem solving for antiretroviral therapy adherence: a randomized trial
    Robert Gross
    Division of Infectious Diseases, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104 6021, USA
    JAMA Intern Med 173:300-6. 2013
  2. doi request reprint How long is the window of opportunity between adherence failure and virologic failure on efavirenz-based HAART?
    Robert Gross
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
    HIV Clin Trials 9:202-6. 2008
  3. pmc Modified directly observed antiretroviral therapy compared with self-administered therapy in treatment-naive HIV-1-infected patients: a randomized trial
    Robert Gross
    Department of Medicine Infectious Diseases, Center for Clinical Epidemiology and Biostatistics, and Center for Education and Research in Therapeutics, Univ of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Arch Intern Med 169:1224-32. 2009
  4. doi request reprint Validity and comparison of two measures of days supply in Medicaid claims data
    Robert Gross
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Pharmacoepidemiol Drug Saf 17:1029-32. 2008
  5. pmc Can we predict daily adherence to warfarin?: Results from the International Normalized Ratio Adherence and Genetics (IN-RANGE) Study
    Alec B Platt
    MSCE, University of Pennsylvania School of Medicine, 707 Blockley Hall, 423 Guardian Dr, Philadelphia, PA 19104 6021, USA
    Chest 137:883-9. 2010
  6. ncbi request reprint HIV-1-specific CD4+ T cell responses in chronically HIV-1 infected blippers on antiretroviral therapy in relation to viral replication following treatment interruption
    Emmanouil Papasavvas
    The Wistar Institute, Philadelphia, Pennsylvania 19104, USA
    J Clin Immunol 26:40-54. 2006
  7. pmc Incidence of transaminitis among HIV-infected patients with occult hepatitis B
    Vincent Lo Re
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Virol 43:32-6. 2008
  8. pmc Overestimates of survival after HAART: implications for global scale-up efforts
    Gregory P Bisson
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    PLoS ONE 3:e1725. 2008
  9. pmc Adherence to hepatitis C virus therapy in HIV/hepatitis C-coinfected patients
    Vincent Lo Re
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    AIDS Behav 17:94-103. 2013
  10. pmc Adherence to warfarin assessed by electronic pill caps, clinician assessment, and patient reports: results from the IN-RANGE study
    Catherine S Parker
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 717 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    J Gen Intern Med 22:1254-9. 2007

Detail Information

Publications57

  1. doi request reprint Managed problem solving for antiretroviral therapy adherence: a randomized trial
    Robert Gross
    Division of Infectious Diseases, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104 6021, USA
    JAMA Intern Med 173:300-6. 2013
    ..We sought to determine whether an intervention derived from problem solving theory, Managed Problem Solving (MAPS), would improve antiretroviral outcomes...
  2. doi request reprint How long is the window of opportunity between adherence failure and virologic failure on efavirenz-based HAART?
    Robert Gross
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
    HIV Clin Trials 9:202-6. 2008
    ..The time between onset of nonadherence and onset of virological failure is unknown. However, this information is critical to the design, implementation, and testing of interventions aiming to forestall treatment failure...
  3. pmc Modified directly observed antiretroviral therapy compared with self-administered therapy in treatment-naive HIV-1-infected patients: a randomized trial
    Robert Gross
    Department of Medicine Infectious Diseases, Center for Clinical Epidemiology and Biostatistics, and Center for Education and Research in Therapeutics, Univ of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Arch Intern Med 169:1224-32. 2009
    ..Success of antiretroviral therapy depends on high rates of adherence, but few interventions are effective. Our objective was to determine if modified directly observed therapy (mDOT) improves initial antiretroviral success...
  4. doi request reprint Validity and comparison of two measures of days supply in Medicaid claims data
    Robert Gross
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Pharmacoepidemiol Drug Saf 17:1029-32. 2008
    ..The two measures should yield the same duration, but if not, the preferred method is unknown...
  5. pmc Can we predict daily adherence to warfarin?: Results from the International Normalized Ratio Adherence and Genetics (IN-RANGE) Study
    Alec B Platt
    MSCE, University of Pennsylvania School of Medicine, 707 Blockley Hall, 423 Guardian Dr, Philadelphia, PA 19104 6021, USA
    Chest 137:883-9. 2010
    ..Currently, no comprehensive screening tool exists to help providers assess the risk of nonadherence at the time of initiation of warfarin therapy...
  6. ncbi request reprint HIV-1-specific CD4+ T cell responses in chronically HIV-1 infected blippers on antiretroviral therapy in relation to viral replication following treatment interruption
    Emmanouil Papasavvas
    The Wistar Institute, Philadelphia, Pennsylvania 19104, USA
    J Clin Immunol 26:40-54. 2006
    ..04) with no difference between groups by week 24. These data support that blippers have higher anti-HIV lymphoproliferative responses while on ART but experience equal to higher viral rebound as compared to matched non-blippers upon TI...
  7. pmc Incidence of transaminitis among HIV-infected patients with occult hepatitis B
    Vincent Lo Re
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Virol 43:32-6. 2008
    ..This information is needed to determine the importance of detecting and treating occult HBV in this population...
  8. pmc Overestimates of survival after HAART: implications for global scale-up efforts
    Gregory P Bisson
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    PLoS ONE 3:e1725. 2008
    ..Determining definitive outcomes of these lost patients, and the effects of losses to follow-up on estimates of survival and risk factors for death after HAART, are key to monitoring the effectiveness of global HAART scale-up efforts...
  9. pmc Adherence to hepatitis C virus therapy in HIV/hepatitis C-coinfected patients
    Vincent Lo Re
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    AIDS Behav 17:94-103. 2013
    ..Among HIV/HCV patients, EVR and SVR increased with higher interferon and ribavirin adherence. Adherence to both antivirals declined over time, but more so for ribavirin...
  10. pmc Adherence to warfarin assessed by electronic pill caps, clinician assessment, and patient reports: results from the IN-RANGE study
    Catherine S Parker
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 717 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    J Gen Intern Med 22:1254-9. 2007
    ..Patient adherence to warfarin may influence anticoagulation control; yet, adherence among warfarin users has not been rigorously studied...
  11. pmc Adherence to hepatitis C virus therapy and early virologic outcomes
    Vincent Lo Re
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, 423 Guardian Dr, Philadelphia, PA 19104 6021, USA
    Clin Infect Dis 48:186-93. 2009
    ..We examined the relationship between adherence to pegylated interferon and ribavirin therapy, measured by pharmacy refill, and HCV suppression during the initial 12 weeks of therapy...
  12. pmc Risk factors for nonadherence to warfarin: results from the IN-RANGE study
    Alec B Platt
    Department of Medicine, University of Pennsylvania School of Medicine, PA, USA
    Pharmacoepidemiol Drug Saf 17:853-60. 2008
    ..Warfarin is widely used to prevent stroke and venous thromboembolism despite its narrow therapeutic window. Warfarin nonadherence is a substantial problem, but risk factors have not been well elucidated...
  13. doi request reprint Antiretroviral failure despite high levels of adherence: discordant adherence-response relationship in Botswana
    Gregory P Bisson
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Acquir Immune Defic Syndr 49:107-10. 2008
    ..Although adherence to antiretroviral therapy may be higher in sub-Saharan Africa, knowledge regarding the magnitude of adherence needed to maintain virological suppression in this setting is limited...
  14. ncbi request reprint Diagnostic accuracy of CD4 cell count increase for virologic response after initiating highly active antiretroviral therapy
    Gregory P Bisson
    Department of Medicine, Division of Infectious Diseases, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania19104 6021, USA
    AIDS 20:1613-9. 2006
    ..To derive and internally validate a clinical prediction rule for virologic response based on CD4 cell count increase after initiation of HAART in a resource-limited setting...
  15. pmc Randomized, controlled trial of therapy interruption in chronic HIV-1 infection
    Emmanouil Papasavvas
    The Wistar Institute, Philadelphia, Pennsylvania, USA
    PLoS Med 1:e64. 2004
    ....
  16. ncbi request reprint Self-reported hepatitis B and C virus infections had low sensitivity among HIV-infected patients
    Vincent Lo Re
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Epidemiol 60:294-9. 2007
    ..To determine the validity of self-reported hepatitis B virus (HBV) and hepatitis C virus (HCV) in HIV-infected injection drug users (IDUs) vs. nonIDUs...
  17. ncbi request reprint A simple, dynamic measure of antiretroviral therapy adherence predicts failure to maintain HIV-1 suppression
    Robert Gross
    Division of Infectious Diseases, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, Center for Education and Research in Therapeutics, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    J Infect Dis 194:1108-14. 2006
    ....
  18. ncbi request reprint Prevalence, risk factors, and outcomes for occult hepatitis B virus infection among HIV-infected patients
    Vincent Lo Re
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
    J Acquir Immune Defic Syndr 44:315-20. 2007
    ..The prevalence of occult HBV in HIV-infected patients remains controversial, and the risk factors and clinical significance are unknown...
  19. pmc Antiretroviral therapy interruptions result in loss of protective humoral immunity to neoantigens in HIV-infected individuals
    Livio Azzoni
    The Wistar Institute, Philadelphia, Pennsylvania, USA
    AIDS 26:1355-62. 2012
    ..As ART interruption occur frequently in resource-constrained settings, we studied their effects on the ability to mount humoral immune responses against a neoantigen...
  20. pmc Relationship between adherence to hepatitis C virus therapy and virologic outcomes: a cohort study
    Vincent Lo Re
    University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Ann Intern Med 155:353-60. 2011
    ..Adherence to therapy with pegylated interferon and ribavirin for hepatitis C virus (HCV) infection has been incompletely examined...
  21. pmc Pharmacy refill adherence compared with CD4 count changes for monitoring HIV-infected adults on antiretroviral therapy
    Gregory P Bisson
    Department of Medicine, Division of Infectious Diseases, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
    PLoS Med 5:e109. 2008
    ....
  22. pmc The Effects of a Problem Solving-Based Intervention on Depressive Symptoms and HIV Medication Adherence Are Independent
    Robert Gross
    Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America Center for Pharmacoepidemiology Research and Training, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America Division of Infectious Diseases, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 9:e84952. 2014
    ..Thus, interventions for medication adherence may not need to address depressive symptoms in order to impact both adherence and depression; this remains to be confirmed, however, in other data. ..
  23. ncbi request reprint Out-of-pocket costs of HAART limit HIV treatment responses in Botswana's private sector
    Gregory P Bisson
    Division of Infectious Disease, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    AIDS 20:1333-6. 2006
    ..001]. HAART costs should be minimized as scale-up efforts in sub-Saharan Africa progress...
  24. pmc Association between efavirenz-based compared with nevirapine-based antiretroviral regimens and virological failure in HIV-infected children
    Elizabeth D Lowenthal
    Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA
    JAMA 309:1803-9. 2013
    ..Data on the comparative effectiveness of these medications in children are limited...
  25. pmc Early mortality and AIDS progression despite high initial antiretroviral therapy adherence and virologic suppression in Botswana
    Katherine T Steele
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e20010. 2011
    ..We sought to determine the relationship between very early ART adherence and early adverse outcomes in HIV-infected adults in Botswana...
  26. doi request reprint A randomized trial of a nursing intervention for HIV disease management among persons with serious mental illness
    Michael B Blank
    Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104 3309, USA
    Psychiatr Serv 62:1318-24. 2011
    ..The objective of this study was to test the effectiveness of a community-based advanced practice nurse (APN) intervention (PATH, Preventing AIDS Through Health) to promote adherence to HIV and psychiatric treatment regimens...
  27. ncbi request reprint Effect of GB virus C viremia on HIV acquisition and HIV set-point
    Gregory P Bisson
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    AIDS 19:1910-2. 2005
    ..32; 95% confidence interval 0.6-2.6). Pre-existing GBV-C viremia at the time of HIV acquisition was also not associated with lower plasma HIV-RNA levels...
  28. pmc Lack of association between retrospectively collected pharmacy refill data and electronic drug monitoring of antiretroviral adherence
    Trisha Acri
    Department of Family and Community Medicine, Temple University, Philadelphia, PA 19140, USA
    AIDS Behav 14:748-54. 2010
    ..Reassessment of the relation between pharmacy refill data and EDM would be warranted when pharmacy refill data is collected as soon as feasible from sources with complete data capture...
  29. ncbi request reprint A time-to-prescription-refill measure of antiretroviral adherence predicted changes in viral load in HIV
    Robert Grossberg
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Epidemiol 57:1107-10. 2004
    ..The goal of this study was to determine the validity and utility of a pharmacy-based time-to-refill measure of antiretroviral therapy adherence...
  30. ncbi request reprint Incidence and risk factors for weight loss during dual HIV/hepatitis C virus therapy
    Vincent Lo Re
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
    J Acquir Immune Defic Syndr 44:344-50. 2007
    ..Clinical observations suggest that patients with HIV/hepatitis C virus (HCV) may lose body weight during dual therapy, but this has not been confirmed analytically...
  31. pmc Abacavir/lamivudine versus tenofovir DF/emtricitabine as part of combination regimens for initial treatment of HIV: final results
    Paul E Sax
    Division of Infectious Diseases, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Infect Dis 204:1191-201. 2011
    ..Due to higher virologic failure with ABC/3TC in the high HIV RNA stratum, blinded treatment was stopped in this group, but study follow-up continued for all patients...
  32. ncbi request reprint HIV/AIDS-specific quality of life and adherence to antiretroviral therapy over time
    William C Holmes
    Center for Health Equity Research and Promotion, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, USA
    J Acquir Immune Defic Syndr 46:323-7. 2007
    ..To determine if HIV/AIDS-specific quality of life (QOL) predicts adherence to antiretroviral therapy (ART)...
  33. pmc Early immunologic failure is associated with early mortality among advanced HIV-infected adults initiating antiretroviral therapy with active tuberculosis
    Shruthi Ravimohan
    Department of Medicine, Division of Infectious Diseases
    J Infect Dis 208:1784-93. 2013
    ..The relationship between antiretroviral therapy (ART) response and early mortality after ART initiation is unknown. We hypothesized that early mortality is associated with decreased early immunologic response to ART...
  34. pmc Pain, mood, and substance abuse in HIV: implications for clinic visit utilization, antiretroviral therapy adherence, and virologic failure
    Jessica S Merlin
    Division of Infectious Diseases, Department of Medicine, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
    J Acquir Immune Defic Syndr 61:164-70. 2012
    ..Our objective was to investigate the relationship between pain, alone and in the context of mood disorders and substance abuse, on clinic utilization, antiretroviral therapy adherence, and virologic suppression...
  35. pmc Association between HIV replication and serum leptin levels: an observational study of a cohort of HIV-1-infected South African women
    Livio Azzoni
    The Wistar Institute, Philadelphia, PA, USA
    J Int AIDS Soc 13:33. 2010
    ..Advanced HIV infection can result in lipoatrophy and wasting, even in the absence of ongoing opportunistic infections, suggesting that HIV may directly affect adipose tissue amount and distribution...
  36. ncbi request reprint Provider inaccuracy in assessing adherence and outcomes with newly initiated antiretroviral therapy
    Robert Gross
    Division on of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    AIDS 16:1835-7. 2002
    ..Therefore, HAART should not be withheld solely on provider predictions of adherence. Providers should not rely on their own assessments when attempting to determine if patients are adhering to therapy...
  37. ncbi request reprint Presence of human immunodeficiency virus-1-specific CD4 and CD8 cellular immune responses in children with full or partial virus suppression
    Emmanouil Papasavvas
    The Wistar Institute, Philadelphia, USA
    J Infect Dis 188:873-82. 2003
    ..Overall, a history of stable CD4(+) T cell counts, as a result of therapy that imparted full or partial virus suppression, was associated with increased levels of anti-HIV CD4(+) T helper responses and decreased T cell activation...
  38. ncbi request reprint Use of pharmacy refill data as a measure of antiretroviral adherence
    Robert Grossberg
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 804 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    Curr HIV/AIDS Rep 4:187-91. 2007
    ..Given the utility of this adherence measurement, it is likely that pharmacy refill will be the method of choice for measuring antiretroviral adherence in an increasing number of clinical and research settings...
  39. doi request reprint Heterogeneity among studies in rates of decline of antiretroviral therapy adherence over time: results from the multisite adherence collaboration on HIV 14 study
    Ira B Wilson
    Department of Health Services, Policy and Practice, Brown University School of Public Health, Brown University, Providence, RI Massachusetts General Hospital, Center for Global Health Ragon Institute of MGH, MIT, and Harvard Harvard Medical School, Boston, MA Division of Public Health and Community Dentistry, University of California at Los Angeles School of Dentistry, University of California at Los Angeles, Los Angeles, CA Department of Psychology, University of Washington, Seattle, WA School of Nursing, Yale University, New Haven, CT Division of Health Services and Outcomes Research, Children s Mercy Hospital and Clinics, University of Missouri Kansas City, Kansas City, MO Department of Medicine Infectious Diseases, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA Department of Medicine, Albert Einstein College of Medicine, Montifiore Hospital, Bronx, NY Department of Psychiatry, Columbia University, New York City, NY and Department of Health and Community Systems, University of Pittsburgh School of Nursing, Pittsburgh, PA
    J Acquir Immune Defic Syndr 64:448-54. 2013
    ..To use electronic drug monitoring to determine if adherence to HIV antiretroviral therapy (ART) changes over time, whether changes are linear, and how the declines vary by study...
  40. pmc Pain and physical and psychological symptoms in ambulatory HIV patients in the current treatment era
    Jessica S Merlin
    Division of Infectious Diseases, Hospital of the University of Pennsylvania and Penn Presbyterian Medical Center, Philadelphia, PA, USA
    J Pain Symptom Manage 43:638-45. 2012
    ..HIV infection has become a manageable chronic disease. There are few studies of pain and symptoms in the current treatment era...
  41. ncbi request reprint A tale of 2 epidemics: the intersection between obesity and HIV infection in Philadelphia
    Valerianna Amorosa
    Division of Infectious Diseases, University of Pennsylvania, Philadelphia, PA 19104 6073, USA
    J Acquir Immune Defic Syndr 39:557-61. 2005
    ..Obesity and HIV infection are ongoing epidemics in the United States. Obesity predisposes to diabetes and cardiovascular disease, which are complications also associated with HIV and/or its treatment...
  42. ncbi request reprint Acceptance of hepatitis B vaccination by pregnant adolescents
    Marilyn Stringer
    School of Nursing, University of Pennsylvania, Philadelphia, USA
    MCN Am J Matern Child Nurs 31:54-60. 2006
    ....
  43. ncbi request reprint Medication beliefs as mediators of the health literacy-antiretroviral adherence relationship in HIV-infected individuals
    Joseph Graham
    Department of Family Medicine and Community Health, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    AIDS Behav 11:385-92. 2007
    ..Although the beliefs assessed do not mediate the relation between literacy and adherence, we identified low adherence norms as a potentially modifiable belief associated with adherence...
  44. pmc Risk factors and predictors for candidemia in pediatric intensive care unit patients: implications for prevention
    Theoklis E Zaoutis
    Division of Infectious Diseases, Center for Pediatric Clinical Effectiveness, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Clin Infect Dis 51:e38-45. 2010
    ..Few data exist on risk factors for candidemia in pediatric intensive care unit (PICU) patients...
  45. ncbi request reprint Natural history of patients with low-level HIV viremia on antiretroviral therapy
    Vincent Lo Re
    Division of Infectious Diseases, Department of Internal Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    AIDS Patient Care STDS 18:436-42. 2004
    ..Higher initial HIV RNA levels and white race were predictors for virologic increase...
  46. doi request reprint Racial disparities in hypertension control, but not treatment intensification
    Craig A Umscheid
    Division of General Internal Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Am J Hypertens 23:54-61. 2010
    ..The objective of this study was to examine whether provider management of uncontrolled hypertension differed by patient race...
  47. pmc Risk factors for medication non-adherence in an HIV infected population in the Dominican Republic
    Julian Harris
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    AIDS Behav 15:1410-5. 2011
    ..Parenting may represent a competing demand on time and resources and be an adherence barrier. Self-reported perceived lack of adherence support may be a useful marker for need for adherence interventions...
  48. doi request reprint Untreated hypertension and the emergency department: a chance to intervene?
    Craig A Umscheid
    Center for Clinical Epidemiology and Biostatistics, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Acad Emerg Med 15:529-36. 2008
    ..The authors investigated the accuracy of identifying HTN in the ED, the proportion of ED patients with untreated HTN, patient characteristics predicting untreated HTN, and provider documentation of untreated HTN...
  49. ncbi request reprint Epidemiologic studies of adverse effects of anti-retroviral drugs: how well is statistical power reported
    Scott D Halpern
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pharmacoepidemiol Drug Saf 14:155-61. 2005
    ..To determine whether there is a difference in average statistical power between pharmacoepidemiologic studies of anti-retroviral adverse drug effects (ADEs) sponsored by for-profit versus non-profit organizations...
  50. doi request reprint Factors Associated with a Willingness to Accept Rapid HIV Testing in an Urban Emergency Department
    Laura Bamford
    Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA
    AIDS Behav 18:250-3. 2014
    ..These results support the need for and acceptability of rapid HIV testing in the ED particularly for individuals who may lack access to this preventive healthcare screening elsewhere. ..
  51. ncbi request reprint The influence of patient adherence on anticoagulation control with warfarin: results from the International Normalized Ratio Adherence and Genetics (IN-RANGE) Study
    Stephen E Kimmel
    Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Arch Intern Med 167:229-35. 2007
    ..Warfarin sodium is a highly efficacious drug, but proper levels of anticoagulation are difficult to maintain. Conflicting data exist on the influence of patient adherence on anticoagulation control...
  52. ncbi request reprint The odds that clinically unrecognized poor or partial adherence confuses population pharmacokinetic/pharmacodynamic analyses
    Bernard Vrijens
    AARDEX Ltd, Zug, Switzerland
    Basic Clin Pharmacol Toxicol 96:225-7. 2005
    ..With the broadening use of electronic monitoring to estimate longitudinal drug exposure, the need exists for an explicit discipline that concerns itself with "what the patient does with the drug". It is called Pharmionics...
  53. ncbi request reprint HIV type 1 chemokine coreceptor use among antiretroviral-experienced patients screened for a clinical trial of a CCR5 inhibitor: AIDS Clinical Trial Group A5211
    Timothy J Wilkin
    Division of International Medicine and Infectious Diseases, Weill Cornell Medical College, New York, NY, USA
    Clin Infect Dis 44:591-5. 2007
    ..Chemokine coreceptor use impacts both the natural history of human immunodeficiency virus type 1 (HIV-1) disease and the potential use of a new class of antiretroviral agents, the CCR5 inhibitors...
  54. ncbi request reprint Monitoring of long-term toxicities of HIV treatments: an international perspective
    Greg Bisson
    AIDS 17:2407-17. 2003
  55. ncbi request reprint Predicting and monitoring antiretroviral adherence
    Robert Gross
    Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA
    LDI Issue Brief 13:1-4. 2007
    ..This Issue Brief summarizes recent studies whose findings may help clinicians predict and monitor their patients' adherence before treatment failure occurs...
  56. ncbi request reprint Adherence to HIV drug therapy
    Robert Gross
    University of Pennsylvania, USA
    LDI Issue Brief 8:1-4. 2002
    ..This Issue Brief summarizes recent work on the effect of adherence on short-term outcomes, and the ability of providers to predict and estimate their patients' adherence to therapy...
  57. ncbi request reprint Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-Infected, treatment-experienced patients: AIDS clinical trials group 5211
    Roy M Gulick
    Weill Medical College of Cornell University, New York, New York, NY, USA
    J Infect Dis 196:304-12. 2007
    ..Vicriviroc, an investigational CCR5 inhibitor, demonstrated short-term antiretroviral activity in a phase 1 study...