Dayna J Groskreutz

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells
    Dayna J Groskreutz
    Division of Pulmonary, Critical Care, and Occupational Medicine, University of Iowa Roy J and Lucille A Carver College of Medicine and Veterans Administration Medical Center, Iowa City, IA 52242, USA
    J Immunol 176:1733-40. 2006
  2. ncbi Respiratory syncytial virus decreases p53 protein to prolong survival of airway epithelial cells
    Dayna J Groskreutz
    Division of Pulmonary, Critical Care, and Occupational Medicine, Department of Pharmacology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, IA 52242, USA
    J Immunol 179:2741-7. 2007
  3. ncbi Cigarette smoke alters respiratory syncytial virus-induced apoptosis and replication
    Dayna J Groskreutz
    Division of Pulmonary, Critical Care, and Occupational Medicine, 100 EMRB, Iowa City, IA 52242, USA
    Am J Respir Cell Mol Biol 41:189-98. 2009
  4. ncbi Respiratory syncytial virus limits alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) phosphorylation to maintain translation and viral replication
    Dayna J Groskreutz
    Division of Pulmonary, Critical Care, and Occupational Medicine, University of Iowa Roy J, Iowa City, IA 52242, USA
    J Biol Chem 285:24023-31. 2010
  5. ncbi Constitutive ERK MAPK activity regulates macrophage ATP production and mitochondrial integrity
    Martha M Monick
    Department of Medicine, University of Iowa Carver College of Medicine and Veterans Administration Medical Center, Iowa City, IA 52242, USA
    J Immunol 180:7485-96. 2008

Detail Information

Publications5

  1. ncbi Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells
    Dayna J Groskreutz
    Division of Pulmonary, Critical Care, and Occupational Medicine, University of Iowa Roy J and Lucille A Carver College of Medicine and Veterans Administration Medical Center, Iowa City, IA 52242, USA
    J Immunol 176:1733-40. 2006
    ..These findings are consistent with the hypothesis that RSV infection sensitizes the airway epithelium to subsequent viral and bacterial exposures by up-regulating TLRs and increasing their membrane localization...
  2. ncbi Respiratory syncytial virus decreases p53 protein to prolong survival of airway epithelial cells
    Dayna J Groskreutz
    Division of Pulmonary, Critical Care, and Occupational Medicine, Department of Pharmacology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, IA 52242, USA
    J Immunol 179:2741-7. 2007
    ..These findings reveal that RSV decreases p53 by enhancing Akt/Mdm2-mediated p53 degradation, thereby delaying apoptosis and prolonging survival of airway epithelial cells...
  3. ncbi Cigarette smoke alters respiratory syncytial virus-induced apoptosis and replication
    Dayna J Groskreutz
    Division of Pulmonary, Critical Care, and Occupational Medicine, 100 EMRB, Iowa City, IA 52242, USA
    Am J Respir Cell Mol Biol 41:189-98. 2009
    ..Cigarette smoke causes necrosis rather than apoptosis in viral infection, resulting in increased inflammation and enhanced viral replication...
  4. ncbi Respiratory syncytial virus limits alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) phosphorylation to maintain translation and viral replication
    Dayna J Groskreutz
    Division of Pulmonary, Critical Care, and Occupational Medicine, University of Iowa Roy J, Iowa City, IA 52242, USA
    J Biol Chem 285:24023-31. 2010
    ..The result is limited phosphorylation of eIF2alpha and continued translation of cellular and viral proteins...
  5. ncbi Constitutive ERK MAPK activity regulates macrophage ATP production and mitochondrial integrity
    Martha M Monick
    Department of Medicine, University of Iowa Carver College of Medicine and Veterans Administration Medical Center, Iowa City, IA 52242, USA
    J Immunol 180:7485-96. 2008
    ..As a composite, these data demonstrate a novel mitochondrial role for ERK in maintaining mitochondrial membrane potential and ATP production in human alveolar macrophages...