Research Topics
Species | Karen GrewenSummaryAffiliation: University of North Carolina Country: USA Publications
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Publications
Relationship quality: effects on ambulatory blood pressure and negative affect in a biracial sample of men and womenKaren M Grewen
Department of Psychiatry, School of Medicine, University of North Carolina at Chapel Hill, North Carolina 27599 7175, USA
Blood Press Monit 10:117-24. 2005..Prospective studies link marriage to better cardiovascular health, but marital dissatisfaction and discord predict increased rates of hypertension, higher blood pressure (BP), greater reactivity to stress, and left ventricular mass...
An investigation of plasma and salivary oxytocin responses in breast- and formula-feeding mothers of infantsKaren M Grewen
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7175, USA
Psychophysiology 47:625-32. 2010..59, p=.022) and Post-Stress Recovery (r=+.59, p=.025). These data suggest that salivary OT assay is feasible, and will be of value where plasma samples are not possible. Validation with larger samples is needed...
Ethnicity is associated with alterations in oxytocin relationships to pain sensitivity in womenKaren M Grewen
Psychiatry, School of Medicine, University of North Carolina at Chapel Hill, USA
Ethn Health 13:219-41. 2008....
Effects of partner support on resting oxytocin, cortisol, norepinephrine, and blood pressure before and after warm partner contactKaren M Grewen
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Psychosom Med 67:531-8. 2005....
Plasma oxytocin is related to lower cardiovascular and sympathetic reactivity to stressKaren M Grewen
University of North Carolina School of Medicine, Department of Psychiatry, CB 7175, Chapel Hill, NC 27599 7175, USA
Biol Psychol 87:340-9. 2011..These data support a cardioprotective role for OT, which may influence the magnitude and hemodynamic determinants of cardiovascular stress responses...
Warm partner contact is related to lower cardiovascular reactivityKaren M Grewen
Department of Psychiatry, University of North Carolina at Chapel Hill, 27599 7175, USA
Behav Med 29:123-30. 2003..These findings suggest that affectionate relationships with a supportive partner may contribute to lower reactivity to stressful life events and may partially mediate the benefit of marital support on better cardiovascular health...
Depressive symptoms are related to higher ambulatory blood pressure in people with a family history of hypertensionKaren M Grewen
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7175, USA
Psychosom Med 66:9-16. 2004..We investigated whether parental history of hypertension (FH+) enhances the impact of depressed mood, indexed by Beck Depression Inventory (BDI), on ambulatory blood pressure (ABP)...
Postprandial ghrelin is elevated in black compared with white womenKimberly A Brownley
Department of Psychiatry, CB 7175, University of North Carolina, Chapel Hill, North Carolina 27599 7175, USA
J Clin Endocrinol Metab 89:4457-63. 2004..These findings suggest subnormal postprandial ghrelin suppression (or faster ghrelin rebound) in black women, especially the obese, that might play a role in their increased prevalence of obesity and cardiovascular disorders...
Transdermal versus oral estrogen therapy in postmenopausal smokers: hemodynamic and endothelial effectsSusan S Girdler
Departments of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599 7175, USA
Obstet Gynecol 103:169-80. 2004....
Dietary sodium restriction alters postprandial ghrelin: implications for race differences in obesityKimberly A Brownley
Department of Psychiatry, University of North Carolina at Chapel Hill 27599 7175, USA
Ethn Dis 16:844-51. 2006..To examine the effect of sodium restriction on the appetite-stimulating hormone, ghrelin, as a function of race, salt sensitivity, and obesity...
Cardiovascular effects of 6 months of hormone replacement therapy versus placebo: differences associated with years since menopauseKimberly A Brownley
Department of Psychiatry, University of North Carolina, Chapel Hill, 27599 7175, USA
Am J Obstet Gynecol 190:1052-8. 2004....
Oxytocinergic activity is linked to lower blood pressure and vascular resistance during stress in postmenopausal women on estrogen replacementKathleen C Light
School of Medicine, University of North Carolina at Chapel Hill, NC 27599 7175, USA
Horm Behav 47:540-8. 2005..The findings suggest that enhanced oxytocinergic activity may contribute to BP decreases associated with ERT in more responsive postmenopausal women...
Deficits in plasma oxytocin responses and increased negative affect, stress, and blood pressure in mothers with cocaine exposure during pregnancyKathleen C Light
Department of Psychiatry, School of Medicine, University of North Carolina, CB 7175 Medical Building A, Chapel Hill 27599 7175, USA
Addict Behav 29:1541-64. 2004..Although they tended to hold their babies less often at home, baby holding in the laboratory led to decreased BP in cocaine mothers who then did not differ from no-drug mothers in BP or observed affect...
More frequent partner hugs and higher oxytocin levels are linked to lower blood pressure and heart rate in premenopausal womenKathleen C Light
Department of Psychiatry, University of North Carolina, CB 7175 Medical Building A, Chapel Hill, NC 27599 7175, USA
Biol Psychol 69:5-21. 2005....
Duration of lactation and incidence of maternal hypertension: a longitudinal cohort studyAlison M Stuebe
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA
Am J Epidemiol 174:1147-58. 2011....
Temporomandibular disorder and optimism: relationships to ischemic pain sensitivity and interleukin-6Nancy L Costello
Dental Research Center, School of Dentistry, Medical Research Building A, University of North Carolina, CB #7175, Chapel Hill, NC 27599-7455, USA
Pain 100:99-110. 2002..Less optimistic TMD patients also had higher NE and IL-6 levels during stress than other TMD patients, while optimism was unrelated to responses in controls (*P<0.05)...
Association between maternal mood and oxytocin response to breastfeedingAlison M Stuebe
1 Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina
J Womens Health (Larchmt) 22:352-61. 2013..Conclusion: Symptoms of depression and anxiety were associated with differences in oxytocin response and affect during breastfeeding...
Failed lactation and perinatal depression: common problems with shared neuroendocrine mechanisms?Alison M Stuebe
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
J Womens Health (Larchmt) 21:264-72. 2012..Research to elucidate the role of these underlying mechanisms may identify treatment strategies both to relieve perinatal depression and to enable women to achieve their infant feeding goals...
Research Grants
- Prenatal Cocaine, Smoking And Oxytocin In HumansKaren Grewen; Fiscal Year: 2007....
