Gail Greendale

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc The biomechanical demands of standing yoga poses in seniors: The Yoga empowers seniors study (YESS)
    Man Ying Wang
    Division of Biokinesiology and Physical Therapy, University of Southern California, 1540 Alcazar St, Los Angeles, CA 90033, USA
    BMC Complement Altern Med 13:8. 2013
  2. pmc Predicting the timeline to the final menstrual period: the study of women's health across the nation
    Gail A Greendale
    Division of Geriatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1687, USA
    J Clin Endocrinol Metab 98:1483-91. 2013
  3. pmc Bone mineral density loss in relation to the final menstrual period in a multiethnic cohort: results from the Study of Women's Health Across the Nation (SWAN)
    Gail A Greendale
    Division of Geriatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1687, USA
    J Bone Miner Res 27:111-8. 2012
  4. pmc Dietary phytoestrogen intakes and cognitive function during the menopausal transition: results from the Study of Women's Health Across the Nation Phytoestrogen Study
    Gail A Greendale
    Division of Geriatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1687, USA
    Menopause 19:894-903. 2012
  5. pmc Active, but not passive cigarette smoking was inversely associated with mammographic density
    Lesley M Butler
    Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523 1681, USA
    Cancer Causes Control 21:301-11. 2010
  6. pmc Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women
    Carolyn J Crandall
    Department of Internal Medicine, David Geffen School of Medicine, University of California, Los Angeles, UCLA Medicine GIM, 911 Broxton Ave, 1st Floor, Los Angeles, CA 90024, USA
    Breast Cancer Res 11:R51. 2009
  7. pmc Positive association between mammographic breast density and bone mineral density in the Postmenopausal Estrogen/Progestin Interventions Study
    Carolyn Crandall
    Division of General Internal Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, USA
    Breast Cancer Res 7:R922-8. 2005
  8. pmc Yoga decreases kyphosis in senior women and men with adult-onset hyperkyphosis: results of a randomized controlled trial
    Gail A Greendale
    Division of Geriatrics, Geffen School of Medicine, University of California at Los Angeles, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095, USA
    J Am Geriatr Soc 57:1569-79. 2009
  9. pmc Effects of the menopause transition and hormone use on cognitive performance in midlife women
    G A Greendale
    Division of Geriatrics, David Geffen School of Medicine at UCLA, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095 1687, USA
    Neurology 72:1850-7. 2009
  10. ncbi request reprint Serum prolactin levels are positively associated with mammographic density in postmenopausal women
    Gail A Greendale
    Division of Geriatrics, David Geffen School of Medicine at UCLA, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095 1687, USA
    Breast Cancer Res Treat 105:337-46. 2007

Detail Information

Publications85

  1. pmc The biomechanical demands of standing yoga poses in seniors: The Yoga empowers seniors study (YESS)
    Man Ying Wang
    Division of Biokinesiology and Physical Therapy, University of Southern California, 1540 Alcazar St, Los Angeles, CA 90033, USA
    BMC Complement Altern Med 13:8. 2013
    ..The primary aim of the Yoga Empowers Seniors Study (YESS) was to use biomechanical methods to quantify the physical demands associated with the performance of 7 commonly-practiced standing yoga poses in older adults...
  2. pmc Predicting the timeline to the final menstrual period: the study of women's health across the nation
    Gail A Greendale
    Division of Geriatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1687, USA
    J Clin Endocrinol Metab 98:1483-91. 2013
    ..Predicting the final menstrual period (FMP) would help women know when their menopause transition will be completed. Additionally, biological changes, such as accelerated bone loss, precede the FMP by at least 1 year...
  3. pmc Bone mineral density loss in relation to the final menstrual period in a multiethnic cohort: results from the Study of Women's Health Across the Nation (SWAN)
    Gail A Greendale
    Division of Geriatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1687, USA
    J Bone Miner Res 27:111-8. 2012
    ..Cumulative FN loss was 9.1%; 5.8% was lost during the transmenopause. Greater BMI and African American heritage were related to slower loss rates, whereas the opposite was true of Japanese and Chinese ancestry...
  4. pmc Dietary phytoestrogen intakes and cognitive function during the menopausal transition: results from the Study of Women's Health Across the Nation Phytoestrogen Study
    Gail A Greendale
    Division of Geriatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1687, USA
    Menopause 19:894-903. 2012
    ..Previous research suggests that higher dietary or supplemental intakes of isoflavones and lignans are related to better cognitive performance in middle-aged and older women...
  5. pmc Active, but not passive cigarette smoking was inversely associated with mammographic density
    Lesley M Butler
    Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523 1681, USA
    Cancer Causes Control 21:301-11. 2010
    ..A negative relation between mammographic density, a strong breast cancer risk factor, and active smoking would lend support for an antiestrogenic mechanism...
  6. pmc Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women
    Carolyn J Crandall
    Department of Internal Medicine, David Geffen School of Medicine, University of California, Los Angeles, UCLA Medicine GIM, 911 Broxton Ave, 1st Floor, Los Angeles, CA 90024, USA
    Breast Cancer Res 11:R51. 2009
    ....
  7. pmc Positive association between mammographic breast density and bone mineral density in the Postmenopausal Estrogen/Progestin Interventions Study
    Carolyn Crandall
    Division of General Internal Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, USA
    Breast Cancer Res 7:R922-8. 2005
    ..We hypothesized that demonstration of an association between mammographic breast density and bone mineral density (BMD) would suggest a unifying underlying mechanism influencing both breast density and BMD...
  8. pmc Yoga decreases kyphosis in senior women and men with adult-onset hyperkyphosis: results of a randomized controlled trial
    Gail A Greendale
    Division of Geriatrics, Geffen School of Medicine, University of California at Los Angeles, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095, USA
    J Am Geriatr Soc 57:1569-79. 2009
    ..To assess whether a specifically designed yoga intervention can reduce hyperkyphosis...
  9. pmc Effects of the menopause transition and hormone use on cognitive performance in midlife women
    G A Greendale
    Division of Geriatrics, David Geffen School of Medicine at UCLA, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095 1687, USA
    Neurology 72:1850-7. 2009
    ..There is almost no longitudinal information about measured cognitive performance during the menopause transition (MT)...
  10. ncbi request reprint Serum prolactin levels are positively associated with mammographic density in postmenopausal women
    Gail A Greendale
    Division of Geriatrics, David Geffen School of Medicine at UCLA, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095 1687, USA
    Breast Cancer Res Treat 105:337-46. 2007
    ..Mammographic density is a strong, independent predictor of breast cancer and, therefore, a potential surrogate indicator of breast cancer risk...
  11. ncbi request reprint The association of endogenous sex steroids and sex steroid binding proteins with mammographic density: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density Study
    Gail A Greendale
    Division of Geriatrics, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095 1687, USA
    Am J Epidemiol 162:826-34. 2005
    ..These results suggest that some sex steroids may increase the risk of breast cancer by stimulating breast epithelial or stromal proliferation, which appears on a mammogram as higher density...
  12. ncbi request reprint Lifestyle factors: are they related to vasomotor symptoms and do they modify the effectiveness or side effects of hormone therapy?
    Gail A Greendale
    Division of Geriatrics, Department of Medicine, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California 90095 1687, USA
    Am J Med 118:148-54. 2005
    ..Whether certain behaviors or BMI raise or lower the risks or benefits of HT remains largely unknown and should be the focus of future research...
  13. ncbi request reprint The association of bone mineral density with estrogen receptor gene polymorphisms
    Gail A Greendale
    Division of Geriatrics, David Geffen School of Medicine at the University of California Los Angeles, California 90095 1687, USA
    Am J Med 119:S79-86. 2006
    ..Among these, ESR2 rs1256030 and ESR2 rs1256065 appear to have an effect at both the lumbar spine and hip in Chinese women and may warrant further study...
  14. ncbi request reprint Hip axis length in mid-life Japanese and Caucasian U.S. residents: no evidence for an ethnic difference
    Gail A Greendale
    Division of Geriatrics, UCLA School of Medicine, Suite 2339, 10945 Le Conte Avenue, 90095, Los Angeles, CA 90095, USA
    Osteoporos Int 14:320-5. 2003
    ..Results were similar in analyses that compared Caucasians to Japanese women born in the US (n=142) or outside the US (n=125). We conclude that there was no Japanese-Caucasian difference in height-adjusted HAL in our study sample...
  15. pmc The reliability and validity of three non-radiological measures of thoracic kyphosis and their relations to the standing radiological Cobb angle
    G A Greendale
    Division of Geriatrics, David Geffen School of Medicine, University of California, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095 1687, USA
    Osteoporos Int 22:1897-905. 2011
    ..By showing that three clinical measures of kyphosis are suitable for use in large scale, longitudinal, hyperkyphosis studies, we will facilitate much needed research in this field...
  16. ncbi request reprint Sport and home physical activity are independently associated with bone density
    Gail A Greendale
    David Geffen School of Medicine at UCLA, Division of Geriatrics, Los Angeles, CA 90095 1687, USA
    Med Sci Sports Exerc 35:506-12. 2003
    ..To study the relations between four domains of physical activity-sport, home, work, and active living-and bone mineral density (BMD)...
  17. pmc Yoga for women with hyperkyphosis: results of a pilot study
    Gail A Greendale
    School of Medicine, Division of Geriatrics, University of California at Los Angeles, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095 1687, USA
    Am J Public Health 92:1611-4. 2002
  18. pmc Menopause-associated symptoms and cognitive performance: results from the study of women's health across the nation
    Gail A Greendale
    University of California, Los Angeles, USA
    Am J Epidemiol 171:1214-24. 2010
    ..The authors found that depressive, anxiety, sleep disturbance, and vasomotor symptoms did not account for the transient decrement in SDMT learning observed during late perimenopause...
  19. ncbi request reprint Dietary soy isoflavones and bone mineral density: results from the study of women's health across the nation
    Gail A Greendale
    Division of Geriatrics, School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095 1687, USA
    Am J Epidemiol 155:746-54. 2002
    ..Adjusted mean spinal BMD of those in the highest tertile of intake was 7.7% greater than that of women in the lowest tertile (p = 0.02); femoral neck BMD was 12% greater in the highest versus the lowest tertile (p < 0.0001)...
  20. pmc Longitudinal analysis of the association between vasomotor symptoms and race/ethnicity across the menopausal transition: study of women's health across the nation
    Ellen B Gold
    Division of Epidemiology, Department of Public Health Sciences, University of California, Davis, CA 95616, USA
    Am J Public Health 96:1226-35. 2006
    ..We also sought to determine whether racial/ethnic differences were explained by sociodemographic, health, or lifestyle factors...
  21. pmc Ethnic differences in use of complementary and alternative medicine at midlife: longitudinal results from SWAN participants
    Yali A Bair
    Department of Epidemiology and Preventive Medicine, University of California, Davis 95616, USA
    Am J Public Health 92:1832-40. 2002
    ..We estimated the prevalence and longitudinal correlates of use of complementary and alternative medicine (CAM) at midlife among participants of the Study of Women's Health Across the Nation (SWAN)...
  22. ncbi request reprint Circulating bioactive androgens in midlife women
    Jiangang Chen
    Center for Health and the Environment, University of California, Davis, California 95616, USA
    J Clin Endocrinol Metab 91:4387-94. 2006
    ..It is important to characterize the biological activity of circulating androgenic steroid hormones during the menopausal transition because these appear to impact the metabolic and cardiovascular health risk factors of women...
  23. ncbi request reprint Use of complementary and alternative medicine during the menopause transition: longitudinal results from the Study of Women's Health Across the Nation
    Yali A Bair
    Planned Parenthood Affiliates of California, Sacramento, CA, USA
    Menopause 15:32-43. 2008
    ..This study examined whether use of complementary and alternative (CAM) therapies during the menopause transition varied by ethnicity...
  24. ncbi request reprint Cross-sectional analysis of specific complementary and alternative medicine (CAM) use by racial/ethnic group and menopausal status: the Study of Women's Health Across the Nation (SWAN)
    Ellen B Gold
    School of Medicine, University of California, Davis, CA 95616, USA
    Menopause 14:612-23. 2007
    ..To examine the relationships of race/ethnicity, menopausal status, health characteristics, and symptoms with use of 21 types of complementary and alternative medicine (CAM) in midlife women...
  25. ncbi request reprint Post-treatment change in serum estrone predicts mammographic percent density changes in women who received combination estrogen and progestin in the Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial
    Giske Ursin
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, Room 4407, USC Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    J Clin Oncol 22:2842-8. 2004
    ..We determined whether increases in serum estrone as a function of treatment predict increases in mammographic percent density...
  26. ncbi request reprint Alcohol use, comorbidity, and mortality
    Alison A Moore
    Department of Medicine, Division of Geriatrics, David Geffen School of Medicine, University of California at Los Angeles, 10945 Le Conte Avenue, Los Angeles, CA 90095, USA
    J Am Geriatr Soc 54:757-62. 2006
    ..To examine the combined influence of alcohol use and comorbidity on 20-year mortality in older adults (average age 66 at the time of the baseline survey)...
  27. pmc Association between menopausal transition stages and developing urinary incontinence
    L Elaine Waetjen
    Department of Obstetrics and Gynecology, University of California, Davis, CA
    Obstet Gynecol 114:989-98. 2009
    ..To estimate whether menopause transition stage is independently associated with the development of incontinence symptoms...
  28. pmc Light to moderate alcohol consumption and disability: variable benefits by health status
    Arun S Karlamangla
    Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA
    Am J Epidemiol 169:96-104. 2009
    ..Alcohol consumption in moderation might reduce the risk of developing physical disability in older adults in good health but not in those in poor health...
  29. doi request reprint Yoga reduces inflammatory signaling in fatigued breast cancer survivors: A randomized controlled trial
    Julienne E Bower
    UCLA Department of Psychology, Los Angeles, CA, United States UCLA Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA, United States Cousins Center for Psychoneuroimmunology, Semel Institute at UCLA, Los Angeles, CA, United States Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, CA, United States Electronic address
    Psychoneuroendocrinology 43:20-9. 2014
    ....
  30. ncbi request reprint Menopause transition stage and endogenous estradiol and follicle-stimulating hormone levels are not related to cognitive performance: cross-sectional results from the study of women's health across the nation (SWAN)
    Crystal Luetters
    David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    J Womens Health (Larchmt) 16:331-44. 2007
    ..We sought to describe the cross-sectional relation between menopause status, estradiol (E(2)), follicle-stimulating hormone (FSH), and measured cognitive function...
  31. ncbi request reprint Obesity and cardiovascular risk factors in younger breast cancer survivors: The Cancer and Menopause Study (CAMS)
    Dena R Herman
    Division of Cancer Prevention and Control Research, UCLA Jonsson Comprehensive Cancer Center, A2 125 CHS, Box 956900, Los Angeles, CA, 90095 6900, USA
    Breast Cancer Res Treat 93:13-23. 2005
    ....
  32. pmc Bone mineral density changes during the menopause transition in a multiethnic cohort of women
    Joel S Finkelstein
    Endocrine Unit, Department of Medicine, Massachusetts General Hospital, 50 Blossom Street, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 93:861-8. 2008
    ..Rates of bone loss across the menopause transition and factors associated with variation in menopausal bone loss are poorly understood...
  33. ncbi request reprint Vitamin D, parathyroid hormone levels and bone mineral density in community-dwelling older women: the Rancho Bernardo Study
    Denise G Von Muhlen
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093, USA
    Osteoporos Int 16:1721-6. 2005
    ..20). However, after the threshold vitamin D level of 120 nmol/l, all PTH values were below 65 ng/l. Further studies are necessary to identify the optimal vitamin D levels necessary to prevent secondary hyperparathyroidism...
  34. ncbi request reprint Hyperkyphotic posture and risk of future osteoporotic fractures: the Rancho Bernardo study
    Mei Hua Huang
    Division of Geriatrics, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, California 90095, USA
    J Bone Miner Res 21:419-23. 2006
    ..In 596 community-dwelling women, we found that with increasing kyphosis, there was a significant trend of increasing fracture risk that was independent of previous history of fractures or BMD...
  35. ncbi request reprint The association between mammographic breast density and bone mineral density in the study of women's health across the nation
    Carolyn J Crandall
    David Geffen School of Medicine at University of California, Los Angeles, CA 90024, USA
    Ann Epidemiol 17:575-83. 2007
    ..Bone mineral density and mammographic breast density are each associated with markers of lifetime estrogen exposure. The association between mammographic breast density and bone mineral density in early perimenopausal women is unknown...
  36. ncbi request reprint Feelings of Usefulness to Others, Disability, and Mortality in Older Adults: the MacArthur Study of Successful Aging
    Tara L Gruenewald
    Department of Medicine Geriatrics, UCLA Geffen School of Medicine, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095 1687, USA
    J Gerontol B Psychol Sci Soc Sci 62:P28-37. 2007
    ..This suggests that feelings of usefulness may shape health trajectories in older adults...
  37. ncbi request reprint Complementary and alternative medicine use among American women: findings from The National Health Interview Survey, 2002
    Dawn M Upchurch
    School of Public Health, University of California, Los Angeles, Los Angeles, California
    J Womens Health (Larchmt) 16:102-13. 2007
    ..This study identified sociodemographic, health, and lifestyle factors associated with use of various types of CAM among women in the United States and examined health conditions and reasons for use...
  38. ncbi request reprint Hyperkyphotic posture and risk of injurious falls in older persons: the Rancho Bernardo Study
    Deborah M Kado
    David Geffen School of Medicine, Los Angeles, CA 90095, USA
    J Gerontol A Biol Sci Med Sci 62:652-7. 2007
    ..Improved identification of those at risk for falls could lead to effective interventions. Because hyperkyphotic posture is associated with impaired physical functioning, we hypothesized that kyphosis may also be associated with falls...
  39. pmc A sociobehavioral model of acupuncture use, patterns, and satisfaction among women in the United States, 2002
    Dawn M Upchurch
    UCLA School of Public Health, Los Angeles, CA 90095 1772, USA
    Womens Health Issues 18:62-71. 2008
    ..To examine the correlates of recent acupuncture use among American women, applying a sociobehavioral model of utilization of conventional health care. Patterns of use, satisfaction, and reasons for acupuncture use are also examined...
  40. pmc Increases in serum estrone sulfate level are associated with increased mammographic density during menopausal hormone therapy
    Carolyn J Crandall
    David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90024, USA
    Cancer Epidemiol Biomarkers Prev 17:1674-81. 2008
    ..Menopausal hormone therapy increases mammographic density. We determined whether increases in serum estrone sulfate (E(1)S) levels during menopausal hormone therapy predict increased mammographic density...
  41. pmc Presence of vasomotor symptoms is associated with lower bone mineral density: a longitudinal analysis
    Carolyn J Crandall
    Department of Internal Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    Menopause 16:239-46. 2009
    ..To determine whether women with vasomotor symptoms (VMS) have lower bone mineral density (BMD) than do women without VMS...
  42. pmc Increased mortality risk in older adults with persistently low or declining feelings of usefulness to others
    Tara L Gruenewald
    University of California, Los Angeles, USA
    J Aging Health 21:398-425. 2009
    ..This study seeks to determine if persistently low or declining feelings of usefulness to others in later life predict increased mortality hazard in older adults...
  43. pmc Predictors of breast discomfort among women initiating menopausal hormone therapy
    Carolyn J Crandall
    Department, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90024, USA
    Menopause 17:462-70. 2010
    ..The aim of this study was to analyze the determinants of breast discomfort among postmenopausal women initiating menopausal hormone therapy (HT)...
  44. pmc Association of menopausal vasomotor symptoms with increased bone turnover during the menopausal transition
    Carolyn J Crandall
    Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90024, USA
    J Bone Miner Res 26:840-9. 2011
    ..We conclude that among early perimenopausal and late perimenopausal women, those with VMS had higher bone turnover than those without VMS. Prior to the final menstrual period, VMS may be a marker for risk of adverse bone health...
  45. ncbi request reprint Increase in epinephrine excretion is associated with cognitive decline in elderly men: MacArthur studies of successful aging
    Arun S Karlamangla
    Division of Geriatrics, David Geffen School of Medicine at UCLA, 10945 Le Conte 2339, Los Angeles, CA 90095 1687, USA
    Psychoneuroendocrinology 30:453-60. 2005
    ..Our objective was to investigate whether increase over time in urinary epinephrine excretion in older adults was associated with subsequent cognitive decline...
  46. ncbi request reprint The effects of hormone therapy on the markers of inflammation and endothelial function and plasma matrix metalloproteinase-9 level in postmenopausal women: the postmenopausal estrogen progestin intervention (PEPI) trial
    Peifeng Hu
    Multicampus Program in Geriatric Medicine and Gerontology, UCLA School of Medicine, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095 1687, USA
    Atherosclerosis 185:347-52. 2006
    ....
  47. pmc Hyperkyphotic posture and poor physical functional ability in older community-dwelling men and women: the Rancho Bernardo study
    Deborah M Kado
    Division of Geriatrics, Department of Medicine, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suite 2339, Los Angeles, CA, USA
    J Gerontol A Biol Sci Med Sci 60:633-7. 2005
    ..Our study objective was to determine the association between hyperkyphotic posture and physical functional limitations...
  48. ncbi request reprint The effects of megestrol acetate suspension for elderly patients with reduced appetite after hospitalization: a phase II randomized clinical trial
    David B Reuben
    UCLA Multicampus Program in Geriatric Medicine and Gerontology, University of California at Los Angeles, Los Angeles, California 90095, USA
    J Am Geriatr Soc 53:970-5. 2005
    ..To provide preliminary evidence on the effectiveness and optimal dosage of megestrol acetate for older persons with impaired appetite after hospitalization...
  49. ncbi request reprint Neurocognitive performance in breast cancer survivors exposed to adjuvant chemotherapy and tamoxifen
    Steven A Castellon
    Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA, USA
    J Clin Exp Neuropsychol 26:955-69. 2004
    ..We highlight ways in which these data converge with other recent studies to suggest that systemic chemotherapy, especially in combination with tamoxifen, can have adverse yet subtle effects on cognitive functioning...
  50. pmc Longitudinal patterns and predictors of alcohol consumption in the United States
    Alison A Moore
    David Geffen School of Medicine at UCLA, Division of Geriatrics, 10945 Le Conte Ave, Suite 2339, Los Angeles, CA 90095 1687, USA
    Am J Public Health 95:458-65. 2005
    ..We examined demographic predictors of longitudinal patterns in alcohol consumption...
  51. ncbi request reprint Association of breast cancer and its therapy with menopause-related symptoms
    Carolyn Crandall
    Division of General Internal Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, 90095 7023, USA
    Menopause 11:519-30. 2004
    ..To study the relationship between current menopause status, occurrence of menopause transition during cancer treatment, and prevalence and severity of possible menopause-related symptoms...
  52. ncbi request reprint Breast cancer in younger women: reproductive and late health effects of treatment
    Patricia A Ganz
    University of California Los Angeles Schools of Medicine and Public Health, USA
    J Clin Oncol 21:4184-93. 2003
    ..In 1997, we initiated a cohort study to evaluate quality of life (QOL) and reproductive health outcomes in younger female breast cancer survivors. Materials and..
  53. ncbi request reprint Hip fracture risk assessment using composite indices of femoral neck strength: the Rancho Bernardo study
    Arun S Karlamangla
    Division of Geriatrics, UCLA School of Medicine, 10945 Le Conte Avenue, Suite 2339, Box 951687, Los Angeles, CA 90095 1687, USA
    Osteoporos Int 15:62-70. 2004
    ..This needs further exploration in larger cohorts and in different population sub-groups...
  54. ncbi request reprint Variation in nutrient intakes by ethnicity: results from the Study of Women's Health Across the Nation (SWAN)
    Mei Hua Huang
    Division of Geriatrics, School of Medicine, University of California, Los Angeles, Los Angeles 90095 1687, California, USA
    Menopause 9:309-19. 2002
    ..To use food frequency questionnaires to summarize the macro- and micronutrient intakes of women of diverse ethnicity in the Study of Women's Health Across the Nation...
  55. ncbi request reprint Continuing education: Comprehensive menopausal assessment: an approach to managing vasomotor and urogenital symptoms in breast cancer survivors
    Laura Zibecchi
    Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA, USA
    Oncol Nurs Forum 30:393-407. 2003
    ..To describe the development and implementation of a comprehensive menopausal assessment (CMA) and intervention program for women with a history of breast cancer...
  56. pmc Demographic, behavioral, and health correlates of complementary and alternative medicine and prayer use among midlife women: 2002
    Dawn M Upchurch
    UCLA School of Public Health, Los Angeles, California 90095 1772, USA
    J Womens Health (Larchmt) 19:23-30. 2010
    ..We also examined the extent to which women used CAM for treatment of health conditions, including menopausal symptoms, and for general health and well-being...
  57. ncbi request reprint Postmenopausal hormone therapy and change in mammographic density
    Gail A Greendale
    Division of Geriatric Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    J Natl Cancer Inst 95:30-7. 2003
    ..Mammographic density is an independent risk factor for breast cancer. Postmenopausal hormone use is associated with an increase in mammographic density, but the magnitude of the density increase is unknown...
  58. ncbi request reprint Hyperkyphotic posture predicts mortality in older community-dwelling men and women: a prospective study
    Deborah M Kado
    Division of Geriatrics, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, California 90095, USA
    J Am Geriatr Soc 52:1662-7. 2004
    ..To determine the association between hyperkyphotic posture and rate of mortality and cause-specific mortality in older persons...
  59. ncbi request reprint Relationships among body weight, joint moments generated during functional activities, and hip bone mass in older adults
    Man Ying Wang
    Department of Kinesiology, California State University, Northridge, CA, USA
    Clin Biomech (Bristol, Avon) 21:717-25. 2006
    ..To investigate the relationships among hip joint moments produced during functional activities and hip bone mass in sedentary older adults...
  60. ncbi request reprint Association of new-onset breast discomfort with an increase in mammographic density during hormone therapy
    Carolyn J Crandall
    Divisions of General Internal Medicine, The David Geffen School of Medicine at UCLA, University of California Los Angeles, 911 Broxton Avenue, Los Angeles, CA 90024, USA
    Arch Intern Med 166:1578-84. 2006
    ..Postmenopausal use of estrogen and progestin therapy increases breast density and breast discomfort. Whether this increase in breast density is heralded by new-onset breast discomfort is unknown...
  61. ncbi request reprint Relation of oxytocin to psychological stress responses and hypothalamic-pituitary-adrenocortical axis activity in older women
    Shelley E Taylor
    Department of Psychology, University of California, Los Angeles, CA 90095, USA
    Psychosom Med 68:238-45. 2006
    ....
  62. ncbi request reprint Comparing a supine radiologic versus standing clinical measurement of kyphosis in older women: the Fracture Intervention Trial
    Deborah M Kado
    Division of Geriatrics, Department of Medicine, The David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095, USA
    Spine (Phila Pa 1976) 31:463-7. 2006
    ..A study of agreement between different measures of kyphosis, a clinical standing measure (Debrunner kyphometer; Protek AG, Bern, Switzerland) versus a supine radiologic measure (Cobb angle)...
  63. ncbi request reprint Progestins affect mechanism of estrogen-induced C-reactive protein stimulation
    David B Reuben
    Multicampus Program in Geriatric Medicine and Gerontology, David Geffen School of Medicine at University of California, Los Angeles 90095 1687, USA
    Am J Med 119:167.e1-8. 2006
    ..To determine whether the mechanisms of C-reactive protein production differ depending on the presence or absence of a progestin in the regimen...
  64. ncbi request reprint Dietary genistein intake and cognitive performance in a multiethnic cohort of midlife women
    Mei Hua Huang
    Division of Geriatrics, Department of Medicine, University of California, Los Angeles, CA 90095, USA
    Menopause 13:621-30. 2006
    ..To examine the relationship between food frequency questionnaire estimated isoflavone intakes and cognitive performance...
  65. ncbi request reprint Lower-extremity biomechanics during forward and lateral stepping activities in older adults
    Man Ying Wang
    Musculoskeletal Biomechanics Research Laboratory, Department of Biokinesiology and Physical Therapy, University of Southern California, 1540 E Alcazar St, CHP 155, Los Angeles, CA 90033, USA
    Clin Biomech (Bristol, Avon) 18:214-21. 2003
    ..To characterize the lower-extremity biomechanics associated with stepping activities in older adults...
  66. pmc Squatting exercises in older adults: kinematic and kinetic comparisons
    Sean Flanagan
    Musculoskeletal Biomechanics Research Laboratory, Department of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA 90089, USA
    Med Sci Sports Exerc 35:635-43. 2003
    ..This study characterized the lower-extremity peak joint angles, peak moments, powers, work, impulse, and muscle recruitment patterns (electromyographic; EMG) associated with two types of squatting activities in elders...
  67. ncbi request reprint Bone mass response to discontinuation of long-term hormone replacement therapy: results from the Postmenopausal Estrogen/Progestin Interventions (PEPI) Safety Follow-up Study
    Gail A Greendale
    University of California at Los Angeles School of Medicine, 10945 Le Conte Ave, Suite 2339, Los Angeles, CA 90095 1687, USA
    Arch Intern Med 162:665-72. 2002
    ..However, the pharmacological doses of estrogens and progestins used are not truly "replacement" in nature...
  68. ncbi request reprint Relation of daily urinary hormone patterns to vasomotor symptoms in a racially/ethnically diverse sample of midlife women: study of women's health across the nation
    Ellen B Gold
    Division of Epidemiology, Department of Public Health Sciences, School of Medicine, University of California, Davis, CA 95616, USA
    Reprod Sci 14:786-97. 2007
    ....
  69. pmc Yoga for persistent fatigue in breast cancer survivors: a randomized controlled trial
    Julienne E Bower
    Department of Psychology, University of California Los Angeles, CA 90095, USA
    Cancer 118:3766-75. 2012
    ..Cancer-related fatigue afflicts up to 33% of breast cancer survivors, yet there are no empirically validated treatments for this symptom...
  70. ncbi request reprint Longitudinal trajectories of heavy drinking in adults in the United States of America
    Arun Karlamangla
    Dvision of Geriatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1687, USA
    Addiction 101:91-9. 2006
    ..To estimate age, period, cohort and other demographic influences on heavy alcohol consumption and trajectories of heavy drinking in American adults...
  71. pmc Factors associated with worsening and improving urinary incontinence across the menopausal transition
    L Elaine Waetjen
    Department of Obstetrics and Gynecology and Statistics, University of California, Davis, California, USA
    Obstet Gynecol 111:667-77. 2008
    ..To evaluate whether the menopausal transition is associated with worsening of urinary incontinence symptoms over 6 years in midlife women...
  72. ncbi request reprint Risk factors for stress fracture among young female cross-country runners
    Jennifer L Kelsey
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA, and Clinical Research Center, Helen Hayes Hospital, West Haverstraw, NY, USA
    Med Sci Sports Exerc 39:1457-63. 2007
    ..To identify risk factors for stress fracture among young female distance runners...
  73. ncbi request reprint Ethnic variation in bone density in premenopausal and early perimenopausal women: effects of anthropometric and lifestyle factors
    Joel S Finkelstein
    Endocrine Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA org
    J Clin Endocrinol Metab 87:3057-67. 2002
    ..Femoral neck BMD is highest in African-Americans and similar in Chinese, Japanese, and Caucasians. These findings may explain why Caucasian women have higher fracture rates than African-Americans and Asians...
  74. ncbi request reprint Cognitive functioning and sex steroid hormone gene polymorphisms in women at midlife
    Howard M Kravitz
    Department of Psychiatry, Rush University Medical Center, Chicago, Illinois 60612, USA
    Am J Med 119:S94-S102. 2006
    ..We conclude that selected genes involved in estrogen synthesis and metabolism may be associated with performance differences on cognitive function tests. Also, the relevant estrogen-related polymorphisms may vary by race/ethnicity...
  75. ncbi request reprint Ethnic variation in bone turnover in pre- and early perimenopausal women: effects of anthropometric and lifestyle factors
    Joel S Finkelstein
    Endocrine Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA org
    J Clin Endocrinol Metab 87:3051-6. 2002
    ..Other factors, such as differences in bone accretion, are likely responsible for much of the ethnic variation in adult BMD...
  76. ncbi request reprint Effects of alcohol and cigarette smoking on change in serum estrone levels in postmenopausal women randomly assigned to fixed doses of conjugated equine estrogens with or without a progestin
    Anna M McDivit
    The Cleveland Clinic, General Internal Medicine, Cleveland, OH, USA
    Menopause 15:382-5. 2008
    ..To determine the effects of alcohol and smoking on serum estrone levels among women assigned to hormone therapy...
  77. ncbi request reprint Body size and ethnicity are associated with menstrual cycle alterations in women in the early menopausal transition: The Study of Women's Health across the Nation (SWAN) Daily Hormone Study
    Nanette Santoro
    Division of Reproductive Endocrinology, Department of Obstetrics, Gynecology and Women s Health, Albert Einstein College of Medicine, New York, New York 10461, USA
    J Clin Endocrinol Metab 89:2622-31. 2004
    ..Comparisons to younger women indirectly support the inhibin hypothesis, which proposes that the initiating event in the menopausal transition is the loss of inhibin negative feedback on FSH secondary to a diminished follicular reserve...
  78. ncbi request reprint Mammographic density in a multiethnic cohort
    Laurel A Habel
    Division of Research, Kaiser Permanente, Oakland, CA 94612, USA
    Menopause 14:891-9. 2007
    ..To compare mammographic density among premenopausal and early perimenopausal women from four racial/ethnic groups and to examine density and acculturation among Japanese and Chinese women...
  79. ncbi request reprint Correlates of sexual function among multi-ethnic middle-aged women: results from the Study of Women's Health Across the Nation (SWAN)
    Nancy E Avis
    Department of Public Health Sciences, Section on Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston Salem, NC 27157 1063, USA
    Menopause 12:385-98. 2005
    ....
  80. ncbi request reprint Physical activity and changes in weight and waist circumference in midlife women: findings from the Study of Women's Health Across the Nation
    Barbara Sternfeld
    Division of Research, Kaiser Permanente, Oakland, CA 94611, USA
    Am J Epidemiol 160:912-22. 2004
    ....
  81. ncbi request reprint Hormone predictors of bone mineral density changes during the menopausal transition
    MaryFran R Sowers
    Department of Epidemiology, School of Public Health, University of Michigan, 339 East Liberty Street, Suite 310, Ann Arbor, MI 48104, USA
    J Clin Endocrinol Metab 91:1261-7. 2006
    ..OBJECTIVE AND CONTEXT: Our objective was to examine predictability of reproductive hormone concentrations for bone mineral density (BMD) loss during the menopausal transition...
  82. ncbi request reprint The relationship of longitudinal change in reproductive hormones and vasomotor symptoms during the menopausal transition
    John F Randolph
    L4228 Women s Hospital, University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, Michigan 48109 0276, USA
    J Clin Endocrinol Metab 90:6106-12. 2005
    ..Vasomotor symptoms are reported by 65-76% of women traversing the menopausal transition and are a primary reason for medical intervention during this life stage...
  83. ncbi request reprint Diet and lifestyle factors associated with premenstrual symptoms in a racially diverse community sample: Study of Women's Health Across the Nation (SWAN)
    Ellen B Gold
    Department of Public Health Sciences, University of California Davis School of Medicine, Davis, California 95616, USA
    J Womens Health (Larchmt) 16:641-56. 2007
    ....
  84. ncbi request reprint The effect of oral contraceptives on bone mass and stress fractures in female runners
    Kristin L Cobb
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305, and Clinical Research Center, Helen Hayes Hospital, West Haverstraw, NY, USA
    Med Sci Sports Exerc 39:1464-73. 2007
    ..To determine the effect of oral contraceptives (OC) on bone mass and stress fracture incidence in young female distance runners...
  85. doi request reprint Physical activity and mammographic density in a cohort of midlife women
    Nina Oestreicher
    Kaiser Permanente Division of Research, Oakland, CA 94612, USA
    Med Sci Sports Exerc 40:451-6. 2008
    ..Physical activity (PA) is one of few modifiable breast cancer risk factors. There have been few studies of the relation between PA and mammographic density, especially in multiethnic populations...

Research Grants17

  1. Dietary and serum phytoestrogens and women's health conditions in midlife
    Gail Greendale; Fiscal Year: 2009
    ..g., hot flashes) or the maintenance of health (e.g., bone density preservation). ..
  2. The Yoga for Hyperkyphosis Trial
    Gail Greendale; Fiscal Year: 2007
    ..At the end of this phase we will again measure study endpoints to assess whether participants have maintained the physical function achieved at the end of the RCT. ..
  3. Study of Woman's Health Across the Nation - UCLA
    Gail Greendale; Fiscal Year: 2007
    ..We will build upon the rich foundation developed during SWAN I and II and link these data to important menopauserelated and health outcomes in SWAN III. ..
  4. Sex Steroids & Mammographic Density in the Postmenopause
    Gail Greendale; Fiscal Year: 2007
    ..We will quantify the relations between the hormone and genetic exposures measured in this project and mammographic density (at baseline as well as change in density between baseline and 12 months). ..
  5. SEX STEROIDS AND MAMMOGRAM DENSITY IN THE POSTMENOPAUSE
    Gail Greendale; Fiscal Year: 2001
    ..The investigators state that this may serve as the first in a series of investigations that would allow identification of those women at higher risk of developing breast toxicity from postmenopausal supplemental hormone use. ..
  6. Dietary and serum phytoestrogens and women's health conditions in midlife
    Gail A Greendale; Fiscal Year: 2010
    ..g., hot flashes) or the maintenance of health (e.g., bone density preservation). ..