Pattie S Green

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Neuronal expression of myeloperoxidase is increased in Alzheimer's disease
    Pattie S Green
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Neurochem 90:724-33. 2004
  2. pmc Combined statin and niacin therapy remodels the high-density lipoprotein proteome
    Pattie S Green
    Department of Medicine, University of Washington, Seattle, WA, USA
    Circulation 118:1259-67. 2008
  3. ncbi request reprint Addition of extended-release niacin to statin therapy: effects on atherosclerotic progression
    Pattie S Green
    Department of Medicine, University of Washington, Seattle, WA, 98108, USA
    Phys Sportsmed 37:160-1. 2009
  4. ncbi request reprint Estrogen therapy fails to alter amyloid deposition in the PDAPP model of Alzheimer's disease
    Pattie S Green
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Endocrinology 146:2774-81. 2005
  5. pmc Aerobic exercise improves cognition for older adults with glucose intolerance, a risk factor for Alzheimer's disease
    Laura D Baker
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA
    J Alzheimers Dis 22:569-79. 2010
  6. ncbi request reprint Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein A-I
    Baohai Shao
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Biol Chem 281:9001-4. 2006
  7. pmc Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trial
    Angela J Hanson
    Geriatric Research, Veterans Affairs Puget Sound Health Care System, University of Washington School of Medicine, Seattle, Washington, USA
    JAMA Neurol 70:972-80. 2013
  8. pmc Cognitive response to estradiol in postmenopausal women is modified by high cortisol
    Laura D Baker
    Department of Psychiatry and Behavioral Science, University of Washington School of Medicine, Seattle, WA, USA
    Neurobiol Aging 33:829.e9-20. 2012
  9. pmc Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial
    Suzanne Craft
    Geriatric Research, Education, and Clinical Center, S 182, Veterans Affairs Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98108, USA
    Arch Neurol 69:29-38. 2012
  10. pmc Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-beta in memory-impaired older adults
    Mark A Reger
    Geriatric Research, Education, and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA
    J Alzheimers Dis 13:323-31. 2008

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Neuronal expression of myeloperoxidase is increased in Alzheimer's disease
    Pattie S Green
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Neurochem 90:724-33. 2004
    ..The increase in neuronal myeloperoxidase expression we observed in Alzheimer disease brains raises the possibility that the enzyme contributes to the oxidative stress implicated in the pathogenesis of the neurodegenerative disorder...
  2. pmc Combined statin and niacin therapy remodels the high-density lipoprotein proteome
    Pattie S Green
    Department of Medicine, University of Washington, Seattle, WA, USA
    Circulation 118:1259-67. 2008
    ..We hypothesized that an intervention that increases HDL levels-combined statin and niacin therapy-might reverse these changes...
  3. ncbi request reprint Addition of extended-release niacin to statin therapy: effects on atherosclerotic progression
    Pattie S Green
    Department of Medicine, University of Washington, Seattle, WA, 98108, USA
    Phys Sportsmed 37:160-1. 2009
    ....
  4. ncbi request reprint Estrogen therapy fails to alter amyloid deposition in the PDAPP model of Alzheimer's disease
    Pattie S Green
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Endocrinology 146:2774-81. 2005
    ..Our observations indicate that long-term estrogen therapy does not alter amyloid pathology in PDAPP mice, an animal model of Alzheimer's disease, and question the role of estrogen in Abeta deposition in brain...
  5. pmc Aerobic exercise improves cognition for older adults with glucose intolerance, a risk factor for Alzheimer's disease
    Laura D Baker
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA
    J Alzheimers Dis 22:569-79. 2010
    ..Although replication in a larger sample is needed, our findings potentially have important therapeutic implications for a growing number of adults at increased risk of cognitive decline...
  6. ncbi request reprint Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein A-I
    Baohai Shao
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Biol Chem 281:9001-4. 2006
    ....
  7. pmc Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trial
    Angela J Hanson
    Geriatric Research, Veterans Affairs Puget Sound Health Care System, University of Washington School of Medicine, Seattle, Washington, USA
    JAMA Neurol 70:972-80. 2013
    ..Lipid-depleted (LD) apolipoproteins are less effective at binding and clearing Aβ, and LD Aβ peptides are more toxic to neurons. However, not much is known about the lipid states of these proteins in human cerebrospinal fluid...
  8. pmc Cognitive response to estradiol in postmenopausal women is modified by high cortisol
    Laura D Baker
    Department of Psychiatry and Behavioral Science, University of Washington School of Medicine, Seattle, WA, USA
    Neurobiol Aging 33:829.e9-20. 2012
    ..Our findings indicate that cognitive and physiological responses to estradiol are adversely affected by elevated stress hormone levels of cortisol in healthy postmenopausal women...
  9. pmc Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial
    Suzanne Craft
    Geriatric Research, Education, and Clinical Center, S 182, Veterans Affairs Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98108, USA
    Arch Neurol 69:29-38. 2012
    ..To examine the effects of intranasal insulin administration on cognition, function, cerebral glucose metabolism, and cerebrospinal fluid biomarkers in adults with amnestic mild cognitive impairment or Alzheimer disease (AD)...
  10. pmc Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-beta in memory-impaired older adults
    Mark A Reger
    Geriatric Research, Education, and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA
    J Alzheimers Dis 13:323-31. 2008
    ..These findings suggest that groups with different genetic risks for AD may show differential dose-response curves following intranasal insulin administration...
  11. ncbi request reprint Myeloperoxidase and inflammatory proteins: pathways for generating dysfunctional high-density lipoprotein in humans
    Tomas Vaisar
    Department of Medicine, HSB BB512, Box 356426, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA
    Curr Atheroscler Rep 9:417-24. 2007
    ..Thus, oxidative modifications to HDL and changes in its protein composition might be useful biomarkers-and perhaps mediators-of CVD...
  12. pmc Effects of aerobic exercise on mild cognitive impairment: a controlled trial
    Laura D Baker
    Departments of Psychiatry and BehavioralScience, University of Washington School of Medicine, Seattle, Washington, USA
    Arch Neurol 67:71-9. 2010
    ..To examine the effects of aerobic exercise on cognition and other biomarkers associated with Alzheimer disease pathology for older adults with mild cognitive impairment, and assess the role of sex as a predictor of response...
  13. pmc Matrix metalloproteinase-9 reduces islet amyloid formation by degrading islet amyloid polypeptide
    Kathryn Aston-Mourney
    Veterans Affairs Puget Sound Health Care System, Seattle, Washington 98108, USA
    J Biol Chem 288:3553-9. 2013
    ..Approaches to increase islet MMP-9 activity could reduce or prevent amyloid deposition and its toxic effects in type 2 diabetes...
  14. pmc Diet intervention and cerebrospinal fluid biomarkers in amnestic mild cognitive impairment
    Jennifer L Bayer-Carter
    Geriatric Research, Education, and Clinical Center, Veterans Affairs Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98108, USA
    Arch Neurol 68:743-52. 2011
    ....
  15. ncbi request reprint Acrolein impairs ATP binding cassette transporter A1-dependent cholesterol export from cells through site-specific modification of apolipoprotein A-I
    Baohai Shao
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Biol Chem 280:36386-96. 2005
    ..Thus, acrolein might contribute to atherogenesis by impairing cholesterol removal from the artery wall...
  16. ncbi request reprint Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study
    G Stennis Watson
    Geriatric Research, Education, and Clinical Center, Research and Development Service, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA
    Am J Geriatr Psychiatry 13:950-8. 2005
    ..Authors evaluated the effects of the PPAR-gamma agonist rosiglitazone on cognition and plasma levels of the APP derivative beta-amyloid (Abeta) in humans...
  17. pmc Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL
    Tomas Vaisar
    Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195, USA
    J Clin Invest 117:746-56. 2007
    ....
  18. pmc MMP-9 sheds the beta2 integrin subunit (CD18) from macrophages
    Tomas Vaisar
    Department of Medicine, School of Medicine, University of Washington, Seattle, Washington 98195, USA
    Mol Cell Proteomics 8:1044-60. 2009
    ....
  19. pmc Neprilysin impedes islet amyloid formation by inhibition of fibril formation rather than peptide degradation
    Sakeneh Zraika
    Department of Medicine, Veterans Affairs Puget Sound Health Care System and University of Washington, Seattle, Washington 98108, USA
    J Biol Chem 285:18177-83. 2010
    ..These findings suggest that targeting the role of neprilysin in IAPP fibril assembly, in addition to IAPP cleavage by other peptidases, may provide a novel approach to reduce and/or prevent islet amyloid deposition in type 2 diabetes...
  20. doi request reprint Spectral index for assessment of differential protein expression in shotgun proteomics
    Xiaoyun Fu
    Department of Medicine, School of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Proteome Res 7:845-54. 2008
    ..Therefore, it should be useful for biomarker discovery and comparisons of protein expression between normal and disease states...
  21. pmc Peripheral amyloid-beta levels regulate amyloid-beta clearance from the central nervous system
    Marcos A Marques
    Geriatric Research, Education, and Clinical Center, Seattle, WA, USA
    J Alzheimers Dis 16:325-9. 2009
    ..We found that elevating peripheral Abetalevels significantly decreased [125I]-Abeta(1-40) brain clearance, thus supporting the hypothesis that peripheral Abeta levels regulate Abeta clearance from the central nervous system...
  22. ncbi request reprint Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults
    Mark A Fishel
    Department of Neurology, University of Washington, Seattle, WA 98108, USA
    Arch Neurol 62:1539-44. 2005
    ..Hyperinsulinemia induces inflammation and is a risk factor for Alzheimer disease. Thus, insulin abnormalities may contribute to Alzheimer disease pathophysiology through effects on the inflammatory network...
  23. pmc GLT-1 loss accelerates cognitive deficit onset in an Alzheimer's disease animal model
    Paramita Mookherjee
    Department of Pathology, University of Washington School of Medicine, Seattle, WA, USA
    J Alzheimers Dis 26:447-55. 2011
    ..These results suggest that deficits in glutamate transporter function compound the effects of familial AD AβPP/PS1 mutant transgenes in younger animals and thus may contribute to early occurring pathogenic processes associated with AD...
  24. pmc Monocyte-to-macrophage differentiation: synthesis and secretion of a complex extracellular matrix
    Mary Y Chang
    Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Biol Chem 287:14122-35. 2012
    ....
  25. ncbi request reprint Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species
    Subramaniam Pennathur
    Department of Medicine, School of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Biol Chem 279:42977-83. 2004
    ..Thus, nitrated HDL might represent a previously unsuspected link between nitrosative stress, atherosclerosis, and inflammation...
  26. ncbi request reprint Effects of chronic glucocorticoid administration on insulin-degrading enzyme and amyloid-beta peptide in the aged macaque
    J Jacob Kulstad
    Geriatric Research, Education, and Clinical Center, Veteran s Affairs Puget Sound Health Care System, Seattle, Washington 98108, USA
    J Neuropathol Exp Neurol 64:139-46. 2005
    ..These findings support the notion that glucocorticoids regulate IDE and provide a mechanism whereby increased glucocorticoid levels may contribute to AD pathology...
  27. ncbi request reprint Estrogen-like compounds for ischemic neuroprotection
    James W Simpkins
    Department of Pharmacology and Neuroscience, 3500 Camp Bowie Blvd, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Stroke 35:2648-51. 2004
    ..These potent, nonfeminizing estrogen analogues are prime candidates for use in stroke neuroprotection...
  28. ncbi request reprint nNOS is involved in estrogen mediated neuroprotection in neuroblastoma cells
    Yi Wen
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, 3500 Camp Bowie Blvd, Fort Worth, TX 76107l, USA
    Neuroreport 15:1515-8. 2004
    ..In SK-N-SH cells, the major estrogen receptor isoforms is estrogen receptor beta. Our current study suggests that increased activity of nNOS may be involved in the neuroprotection conferred by 17beta-estradiol...