Michael Foster Green

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Development of a computerized assessment for visual masking
    Michael Foster Green
    Department of Psychiatry and Biobehavioral Sciences, UCLA, USA
    Int J Methods Psychiatr Res 11:83-9. 2002
  2. pmc Has the generalized deficit become the generalized criticism?
    Michael F Green
    Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA 90024 1759, USA
    Schizophr Bull 39:257-62. 2013
  3. pmc Social cognition in schizophrenia, Part 1: performance across phase of illness
    Michael F Green
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095 6968, USA
    Schizophr Bull 38:854-64. 2012
  4. pmc Social cognition in schizophrenia
    Michael F Green
    University of California, Los Angeles, Semel Institute for Neuroscience and Human Behavior, 300 Medical Plaza, Room 2263, Los Angeles, CA 90095 6968, USA
    Schizophr Bull 34:670-2. 2008
  5. doi request reprint Functional co-primary measures for clinical trials in schizophrenia: results from the MATRICS Psychometric and Standardization Study
    Michael F Green
    Semel Institute for Neuroscience and Human Behavior, UCLA, 300 Medical Plaza, Rm 2263, Los Angeles, CA 90095 6968, USA
    Am J Psychiatry 165:221-8. 2008
  6. ncbi request reprint Stimulating the development of drug treatments to improve cognition in schizophrenia
    Michael F Green
    Semel Neuropsychiatric Institute, Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Annu Rev Clin Psychol 3:159-80. 2007
  7. ncbi request reprint Cognitive impairment and functional outcome in schizophrenia and bipolar disorder
    Michael F Green
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, and the VA Greater Los Angeles Healthcare System 90095 6968, USA
    J Clin Psychiatry 67:3-8; discussion 36-42. 2006
  8. pmc Social cognition in schizophrenia: an NIMH workshop on definitions, assessment, and research opportunities
    Michael F Green
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Schizophr Bull 34:1211-20. 2008
  9. ncbi request reprint Regional brain activity associated with visual backward masking
    Michael F Green
    Department of Psychiatry and Behavioral Sciences, Geffen School of Medicine at University of California, Los Angeles, CA 90095 6968, USA
    J Cogn Neurosci 17:13-23. 2005
  10. ncbi request reprint The FOCIS international survey on psychiatrists' opinions on cognition in schizophrenia
    Michael F Green
    UCLA Neuropsychiatric Institute, Medical Plaza Building 300, Rm 2263, Los Angeles, CA 90095 6968, USA
    Schizophr Res 74:253-61. 2005

Research Grants

  1. EARLY VISUAL PROCESSING IN SCHIZOPHRENIA
    Michael Green; Fiscal Year: 2005
  2. The Genetics of Endophenotypes and Schizophrenia
    Michael Green; Fiscal Year: 2007
  3. EARLY VISUAL PROCESSING IN SCHIZOPHRENIA
    Michael Green; Fiscal Year: 2007
  4. EARLY VISUAL PROCESSING IN SCHIZOPHRENIA
    Michael F Green; Fiscal Year: 2010
  5. 3/6-The Genetics of Endophenotypes and Schizophrenia
    Michael F Green; Fiscal Year: 2010
  6. EARLY VISUAL PROCESSING IN SCHIZOPHRENIA
    Michael Green; Fiscal Year: 2000
  7. Social Cognition and Functioning in Schizophrenia
    Michael F Green; Fiscal Year: 2010

Detail Information

Publications75

  1. ncbi request reprint Development of a computerized assessment for visual masking
    Michael Foster Green
    Department of Psychiatry and Biobehavioral Sciences, UCLA, USA
    Int J Methods Psychiatr Res 11:83-9. 2002
    ....
  2. pmc Has the generalized deficit become the generalized criticism?
    Michael F Green
    Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA 90024 1759, USA
    Schizophr Bull 39:257-62. 2013
    ..This commentary is intended to help clarify the distinctions between these 2 situations so that concerns will be expressed in a more selective, less reflexive, manner...
  3. pmc Social cognition in schizophrenia, Part 1: performance across phase of illness
    Michael F Green
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095 6968, USA
    Schizophr Bull 38:854-64. 2012
    ..An accompanying article prospectively examines the longitudinal stability of social cognition and prediction of functional outcome in the first-episode sample...
  4. pmc Social cognition in schizophrenia
    Michael F Green
    University of California, Los Angeles, Semel Institute for Neuroscience and Human Behavior, 300 Medical Plaza, Room 2263, Los Angeles, CA 90095 6968, USA
    Schizophr Bull 34:670-2. 2008
    ..The articles in this theme summarize data-based studies that have attempted to build or strengthen such bridges to better understand the neural bases of social cognitive impairment in schizophrenia...
  5. doi request reprint Functional co-primary measures for clinical trials in schizophrenia: results from the MATRICS Psychometric and Standardization Study
    Michael F Green
    Semel Institute for Neuroscience and Human Behavior, UCLA, 300 Medical Plaza, Rm 2263, Los Angeles, CA 90095 6968, USA
    Am J Psychiatry 165:221-8. 2008
    ..e., a co-primary) that is considered functionally meaningful. The goal of the current study was to describe steps to evaluate four potential co-primary measures for psychometric properties and validity...
  6. ncbi request reprint Stimulating the development of drug treatments to improve cognition in schizophrenia
    Michael F Green
    Semel Neuropsychiatric Institute, Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Annu Rev Clin Psychol 3:159-80. 2007
    ..This review describes how an area that was primarily of academic interest (cognition in schizophrenia) became a focus of public health concerns and drug-development policy...
  7. ncbi request reprint Cognitive impairment and functional outcome in schizophrenia and bipolar disorder
    Michael F Green
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, and the VA Greater Los Angeles Healthcare System 90095 6968, USA
    J Clin Psychiatry 67:3-8; discussion 36-42. 2006
    ..In addition, cognitive deficits adversely affect functional outcomes in bipolar disorder. This evidence suggests that cognition can be considered a reasonable target for intervention in both schizophrenia and bipolar disorder...
  8. pmc Social cognition in schizophrenia: an NIMH workshop on definitions, assessment, and research opportunities
    Michael F Green
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Schizophr Bull 34:1211-20. 2008
    ..The importance of translational interdisciplinary research teams was emphasized. The current article presents a summary of these discussions...
  9. ncbi request reprint Regional brain activity associated with visual backward masking
    Michael F Green
    Department of Psychiatry and Behavioral Sciences, Geffen School of Medicine at University of California, Los Angeles, CA 90095 6968, USA
    J Cogn Neurosci 17:13-23. 2005
    ..These latter regions (including ventral LO, inferior parietal, anterior cingulate, and thalamus) may form the neural substrate of backward masking...
  10. ncbi request reprint The FOCIS international survey on psychiatrists' opinions on cognition in schizophrenia
    Michael F Green
    UCLA Neuropsychiatric Institute, Medical Plaza Building 300, Rm 2263, Los Angeles, CA 90095 6968, USA
    Schizophr Res 74:253-61. 2005
    ....
  11. ncbi request reprint Forward and backward visual masking in unaffected siblings of schizophrenic patients
    Michael F Green
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at University of California, Los Angeles, USA
    Biol Psychiatry 59:446-51. 2006
    ..Visual masking tasks assess the earliest stages of visual processing. This study examined visual masking performance for forward and backward masking tasks in siblings of schizophrenic patients and healthy comparison subjects...
  12. ncbi request reprint Does risperidone improve verbal working memory in treatment-resistant schizophrenia?
    M F Green
    UCLA Department of Psychiatry and Biobehavioral Sciences 90024 1759, USA
    Am J Psychiatry 154:799-804. 1997
    ....
  13. ncbi request reprint Approaching a consensus cognitive battery for clinical trials in schizophrenia: the NIMH-MATRICS conference to select cognitive domains and test criteria
    Michael F Green
    Neuropsychiatric Institute, Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA
    Biol Psychiatry 56:301-7. 2004
    ..The results from this meeting constitute the initial steps for reaching a consensus cognitive battery for clinical trials in schizophrenia...
  14. ncbi request reprint Backward masking in unmedicated schizophrenic patients in psychotic remission: possible reflection of aberrant cortical oscillation
    M F Green
    Department of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles 90024 1759, USA
    Am J Psychiatry 156:1367-73. 1999
    ..Performance deficits in remitted patients would constitute converging support for this hypothesis...
  15. pmc Visual masking in schizophrenia: overview and theoretical implications
    Michael F Green
    VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    Schizophr Bull 37:700-8. 2011
    ..Finally, we will suggest a possible mechanism that could explain the patterns of masking findings and other visual processing findings in schizophrenia...
  16. doi request reprint Evaluation of functionally meaningful measures for clinical trials of cognition enhancement in schizophrenia
    Michael F Green
    Semel Institute of Neuroscience and Human Behavior, UCLA, Los Angeles, USA
    Am J Psychiatry 168:400-7. 2011
    ..The authors examined the reliability, validity, and practicality of functionally meaningful measures...
  17. pmc Visual masking by object substitution in schizophrenia
    M F Green
    VA Desert Pacific Mental Illness Research, Education, and Clinical Center, Los Angeles, CA, USA
    Psychol Med 41:1489-96. 2011
    ..So far, masking paradigms used in schizophrenia research have been unable to separate these two processes...
  18. pmc Functional neuroanatomy of visual masking deficits in schizophrenia
    Michael F Green
    Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA 90095 6968, USA
    Arch Gen Psychiatry 66:1295-303. 2009
    ..Patients with schizophrenia reliably show deficits on visual masking, and these procedures have been used to explore vulnerability to schizophrenia, probe underlying neural circuits, and help explain functional outcome...
  19. pmc Perception measurement in clinical trials of schizophrenia: promising paradigms from CNTRICS
    Michael F Green
    Semel Institute, UCLA, CA, USA
    Schizophr Bull 35:163-81. 2009
    ..This manuscript describes the ways in which each of these tasks met the criteria used by the breakout group to evaluate and recommend tasks for further development...
  20. ncbi request reprint Social cognition in schizophrenia: recommendations from the measurement and treatment research to improve cognition in schizophrenia new approaches conference
    Michael F Green
    Department of Psychiatry and Behavioral Sciences, Geffen School of Medicine, Los Angeles, CA 90095, USA
    Schizophr Bull 31:882-7. 2005
    ..One of the objectives of this group was to generate recommendations for subsequent human and animal studies, and these research agendas are summarized in this report...
  21. ncbi request reprint Prepulse facilitation and prepulse inhibition in schizophrenia patients and their unaffected siblings
    Jonathan K Wynn
    Department of Psychology MED, University of Southern California, Los Angeles, California 90073, USA
    Biol Psychiatry 55:518-23. 2004
    ..It is less clear whether these information processing deficits extend to prepulse facilitation (PPF), which measures a later stage of generalized alerting or orienting...
  22. ncbi request reprint Cognitive impairment and functional outcome in schizophrenia and bipolar disorder
    Michael F Green
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, USA
    J Clin Psychiatry 67:e12. 2006
    ..Impairments are present in unaffected relatives of patients with schizophrenia or bipolar disorder, can serve as an endophenotype for both illnesses, and are linked to community functioning...
  23. pmc Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of Schizophrenia
    Neal R Swerdlow
    Department of Psychiatry, University of California San Diego, San Diego, California, USA
    Schizophr Res 92:237-51. 2007
    ..Genetic studies now often employ multiple, geographically dispersed test sites to accommodate the need for large and complex study samples. Here, we assessed the feasibility of using PPI in multi-site studies...
  24. ncbi request reprint Biosocial pathways to functional outcome in schizophrenia
    John Brekke
    University of Southern California, School of Social Work, MC 0411, Los Angeles, CA 90089 0411, USA
    Schizophr Res 80:213-25. 2005
    ..Biosocial models are preeminent in the study of schizophrenia, yet there has been little empirical testing of these models...
  25. ncbi request reprint Visual masking as a probe for abnormal gamma range activity in schizophrenia
    Michael Foster Green
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, California 90024 1759, USA
    Biol Psychiatry 53:1113-9. 2003
    ..We conducted two experiments to determine whether visual masking procedures can reveal underlying abnormalities in gamma range oscillations in schizophrenia...
  26. ncbi request reprint The neurocognitive effects of low-dose haloperidol: a two-year comparison with risperidone
    Michael F Green
    Veterans Affairs VISN 22 Mental Illness Research Education and Clinical Center, Los Angeles, California, USA
    Biol Psychiatry 51:972-8. 2002
    ..This study examined the neurocognitive effects of low-dose haloperidol compared with risperidone over a 2-year period...
  27. ncbi request reprint Cross-ethnic differences in perception of emotion in schizophrenia
    John S Brekke
    School of Social Work, University of Southern California, Los Angeles, CA 90089 0411, USA
    Schizophr Res 77:289-98. 2005
    ..It was hypothesized that ethnic minorities would have lower POE scores than Caucasians, and that the differences on POE would remain significant after controlling for neurocognition...
  28. ncbi request reprint Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS
    Michael F Green
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, USA
    Schizophr Res 72:41-51. 2004
    ..These steps are apt to have important implications for clinical trials of cognition-enhancing agents in schizophrenia...
  29. pmc Increased extent of object-selective cortex in schizophrenia
    Jonathan K Wynn
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, USA
    Psychiatry Res 164:97-105. 2008
    ..The findings of abnormal spatial organization of LO in schizophrenia patients may converge with behavioral evidence of deficits in schizophrenia patients for object-recognition tasks that are believed to be mediated by LO activity...
  30. pmc Using event related potentials to explore stages of facial affect recognition deficits in schizophrenia
    Jonathan K Wynn
    VA Greater Los Angeles Healthcare System, MIRECC, Building 210, Los Angeles, CA 90073, USA
    Schizophr Bull 34:679-87. 2008
    ..Our results imply that abnormalities in the later stage of feature decoding could potentially underlie emotion identification deficits in schizophrenia...
  31. pmc Effects of olanzapine, risperidone and haloperidol on prepulse inhibition in schizophrenia patients: a double-blind, randomized controlled trial
    Jonathan K Wynn
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA
    Schizophr Res 95:134-42. 2007
    ..The results are discussed in terms of animal models, neural substrates, and treatment implications...
  32. pmc Errorless learning for training individuals with schizophrenia at a community mental health setting providing work experience
    Robert S Kern
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Schizophr Bull 35:807-15. 2009
    ..There were no group differences on self-esteem, job satisfaction, or work stress. The findings provide modest support for the extensions of EL to community settings for enhancing work performance...
  33. ncbi request reprint Self-efficacy and neurocognition may be related to coping responses in recent-onset schizophrenia
    Joseph Ventura
    UCLA, Department of Psychiatry and Biobehavioral Sciences, 300 Medical Plaza, Room 2243, Los Angeles, CA 90095 6968, USA
    Schizophr Res 69:343-52. 2004
    ..42, p < 0.05). Multiple regression indicated that self-efficacy and sustained attention accounted for 56% of the variance in the use of problem-focused coping, strategies by schizophrenia patients...
  34. pmc Impaired anticipatory event-related potentials in schizophrenia
    Jonathan K Wynn
    VA Greater Los Angeles Healthcare System, University of California, Los Angeles, USA
    Int J Psychophysiol 77:141-9. 2010
    ..Schizophrenia patients demonstrate diminished motor- and non-motor-related anticipatory processing, which may have wide-ranging adverse functional consequences...
  35. ncbi request reprint Neurocognitive performance and functional disability in the psychosis prodrome
    Tara A Niendam
    Department of Psychology, University of California, Los Angeles, Los Angeles, CA 90095 1563, USA
    Schizophr Res 84:100-11. 2006
    ..This study evaluates the pattern of neuropsychological deficits and their association with clinical symptomatology and social functioning in individuals identified as ultra-high-risk (UHR) for psychosis...
  36. ncbi request reprint Extensions of errorless learning for social problem-solving deficits in schizophrenia
    Robert S Kern
    Department of Psychiatry and Biobehavioral Sciences, UCLA Neuropsychiatric Institute and Hospital, Los Angeles, CA, USA
    Am J Psychiatry 162:513-9. 2005
    ..However, errorless learning's applicability to broader, more complex functions is unknown. The present study tested the extension of errorless learning for deficits in social problem-solving skills in patients with schizophrenia...
  37. ncbi request reprint The neurocognitive effects of aripiprazole: an open-label comparison with olanzapine
    Robert S Kern
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, Los Angeles, CA 90073, and Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
    Psychopharmacology (Berl) 187:312-20. 2006
    ..Cognitive deficits are a core feature of schizophrenia. As a target of intervention, improvements in cognition may lead to improvements in functional outcome...
  38. ncbi request reprint Applications of errorless learning for improving work performance in persons with schizophrenia
    Robert S Kern
    UCLA Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA, USA
    Am J Psychiatry 159:1921-6. 2002
    ..The present study tested a training method called errorless learning (which theoretically compensates for neurocognitive impairments) for efficacy at teaching entry-level job tasks to persons with serious and persistent mental illness...
  39. pmc Social cognitive skills training in schizophrenia: an initial efficacy study of stabilized outpatients
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Schizophr Res 107:47-54. 2009
    ....
  40. doi request reprint Emotional intelligence in schizophrenia
    Kimmy S Kee
    Psychology Program, California State University Channel Islands, USA
    Schizophr Res 107:61-8. 2009
    ..D., Salovey, P., Caruso, D.R., 2002. Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT): User's Manual. Multi-Health Systems, Inc., Toronto, Ontario)...
  41. ncbi request reprint Is emotion processing a predictor of functional outcome in schizophrenia?
    Kimmy S Kee
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, USA
    Schizophr Bull 29:487-97. 2003
    ..These findings suggest that emotion processing is a key determinant of work functioning/independent living for individuals with serious mental illness...
  42. pmc Impaired implicit learning in schizophrenia
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, USA
    Neuropsychology 22:606-17. 2008
    ..Discussion focuses on possible explanations for schizophrenia patients' poor probabilistic classification task performance...
  43. pmc Affective traits in schizophrenia and schizotypy
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA
    Schizophr Bull 34:856-74. 2008
    ..Results are discussed in terms of their implications for treatment, etiological models, and future research to advance the study of affective traits in schizophrenia and schizotypy...
  44. ncbi request reprint The timing of negative symptom exacerbations in relationship to positive symptom exacerbations in the early course of schizophrenia
    Joseph Ventura
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles 300 UCLA Medical Plaza, Room 2243, Los Angeles, CA 90095 6968, USA
    Schizophr Res 69:333-42. 2004
    ..Results suggest that the timing of some negative symptom exacerbations is linked to that of positive symptom exacerbations during the early course of schizophrenia...
  45. ncbi request reprint Do the siblings of schizophrenia patients demonstrate affect perception deficits?
    Kimmy S Kee
    University of California, Los Angeles, CA, USA
    Schizophr Res 67:87-94. 2004
    ..These findings demonstrate that subtle deficits in affect perception are detectable in the unaffected siblings of schizophrenia patients when multiple measures of different types of affect perception abilities are used in combination...
  46. ncbi request reprint Lateralized lexical decision in schizophrenia: hemispheric specialization and interhemispheric lexicality priming
    Katherine L Narr
    Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095 1769, USA
    J Abnorm Psychol 112:623-32. 2003
    ..Results suggest that schizophrenia is associated with impaired monitoring and with increased interhemispheric automatic information transfer rather than with changed hemispheric specialization for language or error monitoring...
  47. pmc Further support for the role of dysfunctional attitudes in models of real-world functioning in schizophrenia
    William P Horan
    VA Greater Los Angeles Healthcare System, University of California, Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA 90073, USA
    J Psychiatr Res 44:499-505. 2010
    ..These findings support the value of dysfunctional attitudes for understanding the determinants of outcome in schizophrenia and suggest that therapeutic interventions targeting these attitudes may facilitate functional recovery...
  48. pmc Mismatch negativity, social cognition, and functioning in schizophrenia patients
    Jonathan K Wynn
    Mental Illness Research, Education and Clinical Center, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California, USA
    Biol Psychiatry 67:940-7. 2010
    ..Prior studies found associations between mismatch negativity (MMN), an event-related potential response indexing early auditory processing, and functioning in schizophrenia patients...
  49. pmc Integrity of emotional and motivational states during the prodromal, first-episode, and chronic phases of schizophrenia
    Cindy M Yee
    Department of Psychology, University of California, Los Angeles, Los Angeles, CA 90095 1563, USA
    J Abnorm Psychol 119:71-82. 2010
    ....
  50. pmc Regional brain activity during early visual perception in unaffected siblings of schizophrenia patients
    Junghee Lee
    Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California 90095 6968, USA
    Biol Psychiatry 68:78-85. 2010
    ..We examined the neural substrates of visual backward performance in unaffected sibling of schizophrenia patients using functional magnetic resonance imaging (fMRI)...
  51. pmc The Cognitive Assessment Interview (CAI): development and validation of an empirically derived, brief interview-based measure of cognition
    Joseph Ventura
    Semel Institute for Neuroscience and Human Behavior, Geffen School of Medicine at UCLA, United States
    Schizophr Res 121:24-31. 2010
    ....
  52. pmc Electrophysiological correlates of emotional responding in schizophrenia
    William P Horan
    Department of Psychiatry, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    J Abnorm Psychol 119:18-30. 2010
    ..However, they showed a disruption in a later component associated with sustained attentional processing of emotional stimuli...
  53. pmc Stability of visual masking performance in recent-onset schizophrenia: an 18-month longitudinal study
    Junghee Lee
    Semel Institute for Neuroscience and Human Behavior at UCLA, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, United States
    Schizophr Res 103:266-74. 2008
    ..Furthermore, the stable performance was observed across all four masking conditions. The findings of this study provide further support for the view that visual masking deficits reflect a possible vulnerability marker for schizophrenia...
  54. ncbi request reprint Modulation of attention during visual masking in schizophrenia
    Yuri Rassovsky
    UCLA Department of Psychiatry and Biobehavioral Sciences, 760 Westwood Plaza C8 747 NPI, Los Angeles, CA 90024 1759, USA
    Am J Psychiatry 162:1533-5. 2005
    ..Schizophrenia patients consistently demonstrate performance deficits on visual masking procedures. The present study examined whether attentional manipulation would improve subjects' performance on visual masking...
  55. ncbi request reprint Exploring the short term visual store in schizophrenia using the attentional blink
    Jonathan K Wynn
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, United States
    J Psychiatr Res 40:599-605. 2006
    ..The findings suggest that the enhanced AB effect in schizophrenia reflects an abnormality in their short term visual memory, as opposed to their enhanced susceptibility to visual masking...
  56. ncbi request reprint Does anhedonia in schizophrenia reflect faulty memory for subjectively experienced emotions?
    William P Horan
    Aftercare Research Program, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, 90095, USA
    J Abnorm Psychol 115:496-508. 2006
    ..In-the-moment pleasure and short-term retention for emotional experiences thus appear to be relatively intact in schizophrenia. Alternative explanations for the hedonic deficit in this disorder are discussed...
  57. ncbi request reprint An analysis of categorical perception of facial emotion in schizophrenia
    Kimmy S Kee
    California State University Channel Islands, United States
    Schizophr Res 87:228-37. 2006
    ....
  58. ncbi request reprint Baseline neurocognitive deficits in the CATIE schizophrenia trial
    Richard S E Keefe
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    Neuropsychopharmacology 31:2033-46. 2006
    ..Multiple analyses suggested that a broad cognitive deficit characterizes this sample. These deficits are modestly related to negative symptoms and essentially independent of positive symptom severity...
  59. ncbi request reprint Neurocognitive and social cognitive correlates of formal thought disorder in schizophrenia patients
    Kenneth L Subotnik
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, 90095 6968, USA
    Schizophr Res 85:84-95. 2006
    ..This pattern of findings is consistent with the view that neurocognitive and, possibly, social cognitive deficits underlie these two aspects of formal thinking disturbance in schizophrenia...
  60. ncbi request reprint Sensorimotor gating, orienting and social perception in schizophrenia
    Jonathan K Wynn
    Department of Psychiatry and Biobehavioral Science, Geffen School of Medicine at UCLA, United States
    Schizophr Res 73:319-25. 2005
    ..By showing a link between sensorimotor gating and social perception, this study supports social cognition's potential role as a mediator of the relationship between neurocognition and social functioning in schizophrenia...
  61. ncbi request reprint Visual processing in schizophrenia: Structural equation modeling of visual masking performance
    Yuri Rassovsky
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, 760 Westwood Plaza C8 747 NPI, Los Angeles, CA 90024 1759, USA
    Schizophr Res 78:251-60. 2005
    ..The results also support theories of the different mechanisms underlying performance on these measures...
  62. ncbi request reprint Identification of separable cognitive factors in schizophrenia
    Keith H Nuechterlein
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, USA
    Schizophr Res 72:29-39. 2004
    ..These separable cognitive dimensions also have broader relevance to future research aimed at understanding the nature and structure of core cognitive deficits in schizophrenia...
  63. ncbi request reprint NIMH-MATRICS survey on assessment of neurocognition in schizophrenia
    Robert S Kern
    UCLA Department of Psychiatry and Biobehavioral Sciences, Los Angeles, California, USA
    Schizophr Res 72:11-9. 2004
    ..This article presents the results of the pre-conference survey that was the first step in the RAND process towards development of the NIMH-MATRICS consensus battery to assess cognition in schizophrenia...
  64. pmc Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at University of California Los Angeles, Los Angeles, California 90095 6968, USA
    Schizophr Res 103:218-28. 2008
    ....
  65. ncbi request reprint Event-related gamma activity in schizophrenia patients during a visual backward-masking task
    Jonathan K Wynn
    Department of Psychology, UCLA, Los Angeles, CA, USA
    Am J Psychiatry 162:2330-6. 2005
    ..This study examined event-related gamma range activity during a visual backward-masking task in schizophrenia patients and normal comparison subjects...
  66. doi request reprint The MATRICS Consensus Cognitive Battery, part 1: test selection, reliability, and validity
    Keith H Nuechterlein
    Department of Psychology, UCLA Semel Institute for Neuroscience and Human Behavior, 300 Medical Plaza, Rm 2251, Los Angeles, CA 90095 6968, USA
    Am J Psychiatry 165:203-13. 2008
    ....
  67. doi request reprint The MATRICS Consensus Cognitive Battery, part 2: co-norming and standardization
    Robert S Kern
    Department of Psychology, Geffen School of Medicine, University of California, Los Angeles CA 90073, USA
    Am J Psychiatry 165:214-20. 2008
    ..S. community sample with the battery administered as a unit...
  68. ncbi request reprint Paracontrast and metacontrast in schizophrenia: clarifying the mechanism for visual masking deficits
    Yuri Rassovsky
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, USA
    Schizophr Res 71:485-92. 2004
    ..These results bolster previous conclusions that schizophrenic patients show deficits on visual masking tasks even when masking on those tasks occurs entirely through the interruption mechanism...
  69. pmc Remember and know judgments during recognition in chronic schizophrenia
    Theo G M van Erp
    Department of Psychology, UCLA, Los Angeles, CA 90095, USA
    Schizophr Res 100:181-90. 2008
    ..Taken together, these findings are consistent with a deficit in recollection and increased reliance on familiarity in making recognition memory judgments in chronic schizophrenia...
  70. ncbi request reprint A relationship between neurocognitive impairment and functional impairment in bipolar disorder: a pilot study
    Lori L Altshuler
    Department of Psychiatry, VA Greater Los Angeles Healthcare System, West Los Angeles Medical Center, Los Angeles, CA, USA
    Psychiatry Res 157:289-93. 2008
    ..Poor verbal memory and executive function were associated with functional impairment, suggesting that functional disability may be restricted to a subgroup of cognitively impaired bipolar patients...
  71. ncbi request reprint Neurocognitive function in clinically stable men with bipolar I disorder or schizophrenia and normal control subjects
    Lori L Altshuler
    Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, California, USA
    Biol Psychiatry 56:560-9. 2004
    ..The degree and pattern of impairment between psychiatric groups have rarely been compared, especially when subjects are psychiatrically stable...
  72. pmc Do patients with schizophrenia benefit from a self-referential memory bias?
    Philippe Olivier Harvey
    Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles 90073 1003, United States
    Schizophr Res 127:171-7. 2011
    ..It is not known whether schizophrenia patients benefit from such a memory boost for self-referenced information...
  73. pmc Altered dynamic coupling of lateral occipital complex during visual perception in schizophrenia
    Philippe Olivier Harvey
    Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA
    Neuroimage 55:1219-26. 2011
    ..However, the functional connectivity of LO with other brain regions during visual perception has not been directly investigated in schizophrenia...
  74. pmc Bifactor and item response theory analyses of interviewer report scales of cognitive impairment in schizophrenia
    Steven P Reise
    Department of Psychology, University of California, Los Angeles, CA 90095, USA
    Psychol Assess 23:245-61. 2011
    ..This suggests that these interview-based measures of cognitive deficits could be shortened without loss of measurement precision...
  75. pmc The MCCB impairment profile for schizophrenia outpatients: results from the MATRICS psychometric and standardization study
    Robert S Kern
    UCLA Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, Los Angeles, CA 90073, United States
    Schizophr Res 126:124-31. 2011
    ....

Research Grants22

  1. EARLY VISUAL PROCESSING IN SCHIZOPHRENIA
    Michael Green; Fiscal Year: 2005
    ..This will be accomplished with assessments of social cognition (abilities needed to perceive, interpret, and process social information) and social functioning. ..
  2. The Genetics of Endophenotypes and Schizophrenia
    Michael Green; Fiscal Year: 2007
    ..Findings of heritable deficits in specific measures will be used to guide the next generation of studies of the genetics of schizophrenia. ..
  3. EARLY VISUAL PROCESSING IN SCHIZOPHRENIA
    Michael Green; Fiscal Year: 2007
    ....
  4. EARLY VISUAL PROCESSING IN SCHIZOPHRENIA
    Michael F Green; Fiscal Year: 2010
    ....
  5. 3/6-The Genetics of Endophenotypes and Schizophrenia
    Michael F Green; Fiscal Year: 2010
    ..Once we understand the genetic architecture of these abnormalities, new medications that aim to improve the functioning and quality of life of schizophrenia patients can be developed. ..
  6. EARLY VISUAL PROCESSING IN SCHIZOPHRENIA
    Michael Green; Fiscal Year: 2000
    ..Identification of these basic cognitive components will help us to refine our conceptualization of the specific aspects of cognition that are associated with vulnerability to schizophrenia. ..
  7. Social Cognition and Functioning in Schizophrenia
    Michael F Green; Fiscal Year: 2010
    ....