Affiliation: University of Washington
- Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosisJ D Graves
Department of Immunology, University of Washington Medical Center, Seattle, Washington 98195, USA
J Biol Chem 276:14909-15. 2001..In conclusion, Mst1 activity is regulated by both phosphorylation and proteolysis, suggesting that protein kinase and caspase pathways work in concert to regulate cell death...
- PROTEIN KINASE MST1 AND APOPTOSISJOHNATHAN GRAVES; Fiscal Year: 2002..This may contribute to our understanding of the pathogenesis of human diseases, such as congenital and aquired immunodeficiencies, viral infection, leukemias and lymphomas, where alterations in cell survival have been implicated. ..