Jon E Grant

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. doi request reprint A randomized, placebo-controlled trial of N-acetylcysteine plus imaginal desensitization for nicotine-dependent pathological gamblers
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841 South Maryland Ave, MC 3077, Chicago, IL 60637
    J Clin Psychiatry 75:39-45. 2014
  2. ncbi request reprint A proof of concept study of tolcapone for pathological gambling: relationships with COMT genotype and brain activation
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA Electronic address
    Eur Neuropsychopharmacol 23:1587-96. 2013
  3. ncbi request reprint Phenomenology and treatment of behavioural addictions
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA
    Can J Psychiatry 58:252-9. 2013
  4. pmc White matter abnormalities in skin picking disorder: a diffusion tensor imaging study
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA
    Neuropsychopharmacology 38:763-9. 2013
  5. doi request reprint Memantine reduces stealing behavior and impulsivity in kleptomania: a pilot study
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois 60637, USA
    Int Clin Psychopharmacol 28:106-11. 2013
  6. pmc Telescoping phenomenon in pathological gambling: association with gender and comorbidities
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, IL 60637, USA
    J Nerv Ment Dis 200:996-8. 2012
  7. doi request reprint Skin picking disorder
    Jon E Grant
    Department of Psychiatry and Behavioral Neurosciences, University of Chicago, USA
    Am J Psychiatry 169:1143-9. 2012
  8. pmc Gender-related clinical and neurocognitive differences in individuals seeking treatment for pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, United States
    J Psychiatr Res 46:1206-11. 2012
  9. pmc A pilot study of impulsivity and compulsivity in pathological gambling
    Carlos Blanco
    Department of Psychiatry, Columbia University, New York, NY 10032, United States
    Psychiatry Res 167:161-8. 2009
  10. ncbi request reprint Multicenter investigation of the opioid antagonist nalmefene in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Am J Psychiatry 163:303-12. 2006

Detail Information

Publications80

  1. doi request reprint A randomized, placebo-controlled trial of N-acetylcysteine plus imaginal desensitization for nicotine-dependent pathological gamblers
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841 South Maryland Ave, MC 3077, Chicago, IL 60637
    J Clin Psychiatry 75:39-45. 2014
    ..This study examined the addition of N-acetylcysteine to imaginal desensitization in adults with co-occurring nicotine dependence and pathological gambling...
  2. ncbi request reprint A proof of concept study of tolcapone for pathological gambling: relationships with COMT genotype and brain activation
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA Electronic address
    Eur Neuropsychopharmacol 23:1587-96. 2013
    ..Objective genetic and fMRI markers hold promise in the search for targeting treatment and elucidating brain mechanisms associated with optimal clinical outcomes...
  3. ncbi request reprint Phenomenology and treatment of behavioural addictions
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA
    Can J Psychiatry 58:252-9. 2013
    ..Few studies have examined the efficacy of pharmacological and psychological treatment for the various behavioural addictions, and therefore, currently, no treatment recommendations can be made...
  4. pmc White matter abnormalities in skin picking disorder: a diffusion tensor imaging study
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA
    Neuropsychopharmacology 38:763-9. 2013
    ..This study adds considerable support to the notion that-in addition to the phenomenological and comorbid overlap between SPD and trichotillomania-these disorders likely share overlapping neurobiology...
  5. doi request reprint Memantine reduces stealing behavior and impulsivity in kleptomania: a pilot study
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois 60637, USA
    Int Clin Psychopharmacol 28:106-11. 2013
    ..Memantine was generally well tolerated. This study shows the effectiveness of memantine in reducing urges to shoplift and shoplifting behavior along with improving impulsivity, mood, anxiety, and psychosocial functioning...
  6. pmc Telescoping phenomenon in pathological gambling: association with gender and comorbidities
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, IL 60637, USA
    J Nerv Ment Dis 200:996-8. 2012
    ..This study presents evidence for a gender-specific course of PG unrelated to psychiatric comorbidities and suggests a need for greater clinical focus on the gender differences of gambling behavior...
  7. doi request reprint Skin picking disorder
    Jon E Grant
    Department of Psychiatry and Behavioral Neurosciences, University of Chicago, USA
    Am J Psychiatry 169:1143-9. 2012
    ..Based on clinical experience and research findings, the authors recommend several management approaches to skin picking disorder...
  8. pmc Gender-related clinical and neurocognitive differences in individuals seeking treatment for pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, United States
    J Psychiatr Res 46:1206-11. 2012
    ..The aim of this study was to investigate clinical and cognitive differences in treatment-seeking people with pathological gambling as a function of gender...
  9. pmc A pilot study of impulsivity and compulsivity in pathological gambling
    Carlos Blanco
    Department of Psychiatry, Columbia University, New York, NY 10032, United States
    Psychiatry Res 167:161-8. 2009
    ....
  10. ncbi request reprint Multicenter investigation of the opioid antagonist nalmefene in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Am J Psychiatry 163:303-12. 2006
    ..The authors examined the efficacy and tolerability of the opioid antagonist nalmefene in the treatment of adults with pathological gambling...
  11. pmc Prevalence and correlates of fire-setting in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)
    Carlos Blanco
    Department of Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Box 69, New York, NY 10032, USA
    J Clin Psychiatry 71:1218-25. 2010
    ..To estimate the prevalence, sociodemographic correlates, comorbidity, and rates of mental health service utilization of fire-setters in the general population...
  12. pmc Late-onset pathological gambling: clinical correlates and gender differences
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Psychiatr Res 43:380-7. 2009
    ..Late-onset PG is relatively common and has distinct clinical characteristics suggesting that this population might benefit from unique prevention and treatment strategies...
  13. ncbi request reprint Late-onset obsessive compulsive disorder: clinical characteristics and psychiatric comorbidity
    Jon E Grant
    Department of Psychiatry, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychiatry Res 152:21-7. 2007
    ....
  14. pmc Strategic vs nonstrategic gambling: characteristics of pathological gamblers based on gambling preference
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA
    Ann Clin Psychiatry 23:105-12. 2011
    ..Although prior studies have examined various clinical characteristics of pathological gambling (PG), limited data exist regarding the clinical correlates of PG based on preferred forms of gambling...
  15. doi request reprint Characteristics of pathological gamblers with a problem gambling parent
    Liana Schreiber
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, Minnesota 55454, USA
    Am J Addict 18:462-9. 2009
    ..Treatment approaches may need to be tailored for specific problems secondary to gambling and gender issues based on the history of having a problem gambling parent...
  16. doi request reprint Neurocognitive deficits associated with shoplifting in young adults
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, MN 55454, USA
    Compr Psychiatry 53:1049-55. 2012
    ..Shoplifting is a relatively common behavior in young adults, but the demographic and neuropsychological correlates of shoplifting remain poorly characterized in this context...
  17. doi request reprint Cognitive task performance and frequency of alcohol usage in young adults
    Arit M Harvanko
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, MN 55454, USA
    J Addict Med 6:106-11. 2012
    ..The goal of our study was to examine cognitive effects of alcohol in young adults at varied levels of alcohol usage using well-validated computerized cognitive measures...
  18. pmc Relationship of nicotine dependence, subsyndromal and pathological gambling, and other psychiatric disorders: data from the National Epidemiologic Survey on Alcohol and Related Conditions
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 70:334-43. 2009
    ..Nicotine dependence frequently co-occurs with subsyndromal and pathological levels of gambling. The relationship of nicotine dependence, levels of gambling pathology, and other psychiatric disorders, however, is incompletely understood...
  19. pmc Memantine shows promise in reducing gambling severity and cognitive inflexibility in pathological gambling: a pilot study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopharmacology (Berl) 212:603-12. 2010
    ..Memantine, an N-methyl D-aspartate receptor antagonist, appears to reduce glutamate excitability and improve impulsive decision making, suggesting it may help individuals with PG...
  20. ncbi request reprint N-acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: a pilot study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Biol Psychiatry 62:652-7. 2007
    ..N-acetyl cysteine (NAC), an amino acid, seems to restore extracellular glutamate concentration in the nucleus accumbens and therefore offers promise in reducing addictive behavior...
  21. ncbi request reprint Longitudinal course of pharmacotherapy in obsessive-compulsive disorder
    Jon E Grant
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois 60637, USA
    Int Clin Psychopharmacol 28:200-5. 2013
    ..This 5-year prospective study sought to better understand the long-term course of SRI utilization among individuals with OCD...
  22. doi request reprint Pathologic skin picking
    Brian L Odlaug
    University of Minnesota, Ambulatory Research Center, Department of Psychiatry, Minneapolis, USA
    Am J Drug Alcohol Abuse 36:296-303. 2010
    ..Pathologic skin picking (PSP) is characterized by the repetitive and compulsive picking of skin which results in tissue damage...
  23. pmc The Gambling Symptom Assessment Scale (G-SAS): a reliability and validity study
    Suck Won Kim
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Psychiatry Res 166:76-84. 2009
    ..The correlations between the G-SAS and the PG-YBOCS and Clinical Global Impression rating were excellent. Findings suggest that the G-SAS is reliable and valid in assessing changes in symptoms during a drug treatment study...
  24. pmc A double-blind, placebo-controlled trial of lamotrigine for pathological skin picking: treatment efficacy and neurocognitive predictors of response
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    J Clin Psychopharmacol 30:396-403. 2010
    ..However, these neurocognitive data suggest that lamotrigine may be valuable in a subset of patients who exhibit relatively impaired cognitive flexibility...
  25. pmc Predicting response to opiate antagonists and placebo in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopharmacology (Berl) 200:521-7. 2008
    ..No studies have systematically examined predictors of medication treatment outcome in PG. Understanding clinical variables related to treatment outcome should help generate treatment algorithms for PG...
  26. doi request reprint A Structured Clinical Interview for Kleptomania (SCI-K): preliminary validity and reliability testing
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Int J Methods Psychiatr Res 15:83-94. 2006
    ..These findings require replication in larger groups, including non-psychiatric populations, to examine their generalizability...
  27. ncbi request reprint Update on pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Curr Psychiatry Rep 8:53-8. 2006
    ..Although PG is a disabling disorder that continues to represent a clinical challenge for the healthcare professional, our current knowledge of pharmacotherapy and psychosocial interventions offers potentially effective treatment options...
  28. pmc Shopping problems among high school students
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Compr Psychiatry 52:247-52. 2011
    ..An assessment of adolescent shopping behavior along a continuum of severity and its relationship to other behaviors and health issues is incompletely understood...
  29. doi request reprint Prediction of alcohol and gambling problems in young adults by using a measure of decision making
    Arit M Harvanko
    From the Department of Psychiatry AMH, LRNS, University of Minnesota Medical Center, Minneapolis and Department of Psychiatry and Behavioral Neuroscience JEG, Pritzker School of Medicine, University of Chicago, Chicago, IL
    J Addict Med 7:314-9. 2013
    ..This study aimed to determine whether risky decision making on a cognitive task is predictive of increasing gambling behaviors and alcohol use...
  30. doi request reprint A double-blind, placebo-controlled study of the opiate antagonist, naltrexone, in the treatment of kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Biol Psychiatry 65:600-6. 2009
    ..This study examined the efficacy and tolerability of the opioid antagonist naltrexone in adults with kleptomania who have urges to steal...
  31. pmc Pathological skin picking in individuals with body dysmorphic disorder
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Gen Hosp Psychiatry 28:487-93. 2006
    ..The objective of this study was to examine the prevalence and clinical correlates of pathological skin picking (PSP) in a large sample of individuals with body dysmorphic disorder (BDD)...
  32. pmc Neurocognitive dysfunction in strategic and non-strategic gamblers
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Prog Neuropsychopharmacol Biol Psychiatry 38:336-40. 2012
    ..Whether or not putative pathological gambling subtypes differ in terms of their clinical and cognitive profiles has received little attention...
  33. doi request reprint Cigarette smoking status in pathological gamblers: association with impulsivity and cognitive flexibility
    Marc E Mooney
    University of Minnesota, Department of Psychiatry, Minneapolis, MN 55454, USA
    Drug Alcohol Depend 117:74-7. 2011
    ..This study evaluated impulsivity and cognitive flexibility in a sample of pathological gamblers with differing smoking status...
  34. doi request reprint Motor inhibition and cognitive flexibility in pathologic skin picking
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Prog Neuropsychopharmacol Biol Psychiatry 34:208-11. 2010
    ..This study sought to assess motor inhibitory control and aspects of cognitive flexibility in a sample of individuals with PSP...
  35. doi request reprint A clinical comparison of pathologic skin picking and obsessive-compulsive disorder
    Jon E Grant
    Department of Psychiatry, Ambulatory Research Center, University of Minnesota Medical Center, Minneapolis, MN 55454, USA
    Compr Psychiatry 51:347-52. 2010
    ..This study sought to examine the clinical similarities between PSP and OCD...
  36. doi request reprint Quality of life and clinical severity in pathological skin picking and trichotillomania
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    J Anxiety Disord 24:823-9. 2010
    ..Quality of life was not associated with symptom severity. Larger studies should examine further the impact PSP and TTM have on quality of life as well as the role quality of life itself plays in the severity and duration of illness...
  37. doi request reprint Dronabinol, a cannabinoid agonist, reduces hair pulling in trichotillomania: a pilot study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopharmacology (Berl) 218:493-502. 2011
    ..Trichotillomania is characterized by repetitive pulling causing noticeable hair loss. Pharmacological treatment data for trichotillomania are limited...
  38. doi request reprint A cognitive comparison of pathological skin picking and trichotillomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    J Psychiatr Res 45:1634-8. 2011
    ..The extent to which these disorders share a common cognitive phenotype, however, has yet to be examined. This study sought to compare inhibitory control processes in individuals with PSP or TTM...
  39. ncbi request reprint A double-blind, placebo-controlled study of the opiate antagonist naltrexone in the treatment of pathological gambling urges
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    J Clin Psychiatry 69:783-9. 2008
    ..This study examined the efficacy and tolerability of the opioid antagonist naltrexone in adults with PG who have urges to gamble...
  40. ncbi request reprint Childhood-onset pathologic skin picking: clinical characteristics and psychiatric comorbidity
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Compr Psychiatry 48:388-93. 2007
    ....
  41. ncbi request reprint Clinical characteristics and psychiatric comorbidity of pyromania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 68:1717-22. 2007
    ..This study details the demographic and phenomenological features of individuals with DSM-IV lifetime pyromania...
  42. ncbi request reprint Examination of gender in pathologic grooming behaviors
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychiatr Q 78:259-67. 2007
    ..Further research is needed to validate our findings and identify whether treatments should be specially tailored differently for men and women with grooming disorders...
  43. doi request reprint Legal consequences of kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychiatr Q 80:251-9. 2009
    ..Kleptomania is associated with significant legal repercussions. The findings emphasize the need for rigorous treatment approaches to target kleptomania symptoms and prevent re-offending...
  44. pmc Sexual orientation of men with pathological gambling: prevalence and psychiatric comorbidity in a treatment-seeking sample
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Compr Psychiatry 47:515-8. 2006
    ..04). Psychiatric comorbidity and impairment are high in gay and bisexual men with PG. Research is needed to optimize patient care for gay and bisexual men with PG...
  45. doi request reprint Prevalence, correlates, and comorbidity of DSM-IV obsessive-compulsive personality disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    J Psychiatr Res 46:469-75. 2012
    ..The results highlight the need for further research to identify common pathophysiological elements common to OCPD and associated disorders...
  46. pmc A 6-month follow-up of imaginal desensitization plus motivational interviewing in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 23:3-10. 2011
    ..This study sought to examine whether those benefits were maintained 6 months post-treatment...
  47. ncbi request reprint Lamotrigine treatment of pathologic skin picking: an open-label study
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 68:1384-91. 2007
    ..Although pathologic skin picking is a relatively common behavior, treatment data are limited. We hypothesized that lamotrigine would reduce the symptoms of pathologic skin picking...
  48. ncbi request reprint Safety of high-dose naltrexone treatment: hepatic transaminase profiles among outpatients
    Suck Won Kim
    Department of Psychiatry, Medical School, University of Minnesota, Minneapolis, 55454 1495, USA
    Clin Neuropharmacol 29:77-9. 2006
    ..This study was carried out to test the hypothesis that the hepatic safety profile of prolonged high-dose oral naltrexone (150 mg/d) is acceptable if over-the-counter analgesic use is restricted...
  49. doi request reprint Nalmefene in the treatment of pathological gambling: multicentre, double-blind, placebo-controlled study
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Br J Psychiatry 197:330-1. 2010
    ..These findings suggest that medication dosing may be an important consideration in achieving symptom control...
  50. ncbi request reprint Frontal white matter integrity in borderline personality disorder with self-injurious behavior
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, University of Minnesota, Minneapolis, MN, USA
    J Neuropsychiatry Clin Neurosci 19:383-90. 2007
    ..Women with borderline personality disorder-self-injurious behavior exhibit decreased white matter microstructural integrity in inferior frontal brain regions that may include components of orbito-frontal circuitry...
  51. ncbi request reprint Advances in the pharmacological treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454 1495, USA
    J Gambl Stud 19:85-109. 2003
    ..We also discuss dosage strategies, the duration of treatment, issues surrounding medication compliance, and approaches to treatment-refractory pathological gambling, such as pharmacological and behavioral augmentation...
  52. pmc Imaginal desensitisation plus motivational interviewing for pathological gambling: randomised controlled trial
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Br J Psychiatry 195:266-7. 2009
    ..People who failed to respond to Gamblers Anonymous reported significantly greater reduction in pathological gambling symptoms following later assignment to IDMI. Abstinence was achieved by 63.6% during the acute IDMI treatment period...
  53. ncbi request reprint Escitalopram treatment of pathological gambling with co-occurring anxiety: an open-label pilot study with double-blind discontinuation
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, Minnesota 55454, USA
    Int Clin Psychopharmacol 21:203-9. 2006
    ..Larger, longer, placebo-controlled, double-blind studies are needed to evaluate further the safety and tolerability of escitalopram in the treatment of PG and co-occurring anxiety...
  54. ncbi request reprint Pathological gambling and mood disorders: clinical associations and treatment implications
    Suck Won Kim
    Department of Psychiatry, University of Minnesota Medical School, F282 2A West, 2450 Riverside Avenue, Minneapolis, 55454, USA
    J Affect Disord 92:109-16. 2006
    ..Traditionally, mood and gambling symptoms have been known to overlap. In the present review we attempt to examine the diagnostic associations and implications for treatment...
  55. doi request reprint Personality disorders and dimensions in pathological gambling
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA
    J Pers Disord 26:381-92. 2012
    ..Further exploration of these disorders and dimensions of personality may encourage a more inclusively global treatment approach...
  56. ncbi request reprint Augmentation with naltrexone to treat compulsive sexual behavior: a case series
    Nancy C Raymond
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 22:56-62. 2010
    ..We hypothesized that naltrexone would reduce the urges and behaviors associated with CSB...
  57. ncbi request reprint Update on pathological skin picking
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Curr Psychiatry Rep 11:283-8. 2009
    ..Although the disorder is common, appropriate treatments for PSP are limited. Pharmacotherapeutic and certain cognitive-behavioral interventions have demonstrated promise in treating this disorder and need to be explored further...
  58. pmc Pathologic gambling and bankruptcy
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Compr Psychiatry 51:115-20. 2010
    ..Although prior studies have examined rates of bankruptcy in pathologic gambling (PG), there are only limited data regarding the clinical correlates of those with PG who declare bankruptcy because of gambling...
  59. pmc Pharmacological treatment of adolescent pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Int J Adolesc Med Health 22:129-38. 2010
    ....
  60. doi request reprint N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Arch Gen Psychiatry 66:756-63. 2009
    ..N-acetylcysteine, an amino acid, seems to restore the extracellular glutamate concentration in the nucleus accumbens and, therefore, offers promise in the reduction of compulsive behavior...
  61. ncbi request reprint Tobacco use and pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 17:237-41. 2005
    ..An improved understanding of the relationship would be helpful in treating individuals with co-occurring pathological gambling and nicotine dependence...
  62. ncbi request reprint An open-label study of naltrexone in the treatment of kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis 55454 1495, USA
    J Clin Psychiatry 63:349-56. 2002
    ..The present study was designed to test the short-term efficacy and safety of naltrexone in the treatment of kleptomania...
  63. ncbi request reprint Pathological gambling. Current status and new treatments
    Suck Won Kim
    Department of Psychiatry, University of Minnesota Medical School, USA
    Minn Med 85:48-50, 52. 2002
    ..A brief clinical description of PGD is followed by a summary of published drug treatment outcomes and the basic principles of medication treatment in office practice...
  64. ncbi request reprint A double-blind placebo-controlled study of the efficacy and safety of paroxetine in the treatment of pathological gambling
    Suck Won Kim
    Department of Psychiatry, University of Minnesota, Minneapolis, USA
    J Clin Psychiatry 63:501-7. 2002
    ..This randomized, double-blind, placebo-controlled study investigated the efficacy and tolerability of paroxetine in the treatment of pathological gambling...
  65. ncbi request reprint Understanding and treating kleptomania: new models and new treatments
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Isr J Psychiatry Relat Sci 43:81-7. 2006
    ..Subtyping of individuals with kleptomania may be a useful way to better understand this behavior and decide on effective treatment interventions...
  66. ncbi request reprint Paroxetine treatment of pathological gambling: a multi-centre randomized controlled trial
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, Minnesota 55454 1495, USA
    Int Clin Psychopharmacol 18:243-9. 2003
    ..Paroxetine consistently demonstrated an advantage over placebo on the Clinical Global Impressions scale; however, a larger sample size may have registered significant differences...
  67. ncbi request reprint Alcohol craving in outpatients with alcohol dependence: rate and clinical correlates
    Gihyun Yoon
    Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota 55417, USA
    J Stud Alcohol 67:770-7. 2006
    ..We also examined the relationship between alcohol craving and the clinical characteristics of alcohol-dependent patients...
  68. pmc Impulsivity in the general population: a national study
    Jaime Chamorro
    Department of Psychiatry, Columbia University New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY, USA
    J Psychiatr Res 46:994-1001. 2012
    ..Most existing knowledge about impulsivity comes from clinical samples. To date, no study has estimated the prevalence of impulsivity and examined its correlates in the general population...
  69. doi request reprint Kleptomania: clinical characteristics and relationship to substance use disorders
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, 55454, USA
    Am J Drug Alcohol Abuse 36:291-5. 2010
    ..Although categorized as an impulse control disorder, kleptomania has many features in common with substance use disorders...
  70. pmc Clinical characteristics of trichotillomania with trichophagia
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Compr Psychiatry 49:579-84. 2008
    ..Little is known about trichophagia in individuals with trichotillomania. Although studies have mentioned the behavior, no previous studies have examined clinical correlates of trichophagia...
  71. doi request reprint Clinical characteristics and medical complications of pathologic skin picking
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Gen Hosp Psychiatry 30:61-6. 2008
    ..This study sought to detail the phenomenology and medical consequences of pathologic skin picking (PSP)...
  72. pmc Emotion regulation and impulsivity in young adults
    Liana R N Schreiber
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, MN, USA
    J Psychiatr Res 46:651-8. 2012
    ....
  73. ncbi request reprint Open-label pilot study of memantine in the treatment of compulsive buying
    Jon E Grant
    Department of Psychiatry, University of Minnesota, School of Medicine, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 24:119-26. 2012
    ..Memantine, an N-methyl-D-aspartate receptor antagonist, appears to reduce glutamate excitability and improve impulsive behaviors, suggesting it may help individuals with CB...
  74. ncbi request reprint Neuropsychological functioning in kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Behav Res Ther 45:1663-70. 2007
    ..693, p=0.004). As a group, subjects with kleptomania did not demonstrate deficits on neuropsychological testing. Greater kleptomania symptom severity, however, was correlated with impairment in executive functioning...
  75. ncbi request reprint Paraphilias in adult psychiatric inpatients
    Patrick J Marsh
    Department of Psychiatry, University of South Florida, Tampa, FL 33613, USA
    Ann Clin Psychiatry 22:129-34. 2010
    ..The goal of the present study was to examine the prevalence of paraphilias in an adult inpatient psychiatric population...
  76. ncbi request reprint Impulse-control disorders in adolescent psychiatric inpatients: co-occurring disorders and sex differences
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 68:1584-92. 2007
    ..To examine in a sex-sensitive manner the frequencies, clinical correlates, and patterns of co-occurrence of impulse-control disorders in adolescent psychiatric inpatients...
  77. pmc Stealing among high school students: prevalence and clinical correlates
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    J Am Acad Psychiatry Law 39:44-52. 2011
    ..Significant distress and loss of control over this behavior suggest that stealing often has significant associated morbidity...
  78. ncbi request reprint Trichotillomania and Pathologic Skin Picking: clinical comparison with an examination of comorbidity
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, Minnesota 55454, USA
    Ann Clin Psychiatry 20:57-63. 2008
    ..We sought to examine the similarities and differences between these three groups from a clinical viewpoint...
  79. pmc Neuropsychological deficits associated with cannabis use in young adults
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, United States
    Drug Alcohol Depend 121:159-62. 2012
    ..It is unclear whether such impairment can occur in the absence of potential confounding influences of co-morbid axis-I disorders and use of other illicit substances...
  80. doi request reprint Personality dimensions and disorders in pathological gambling
    Brian L Odlaug
    Department of Public Health, University of Copenhagen, Copenhagen, Denmark
    Curr Opin Psychiatry 26:107-12. 2013
    ..This review presents the most current research in personality dimensions and disorders with respect to pathological gambling...