J E Grant

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi Open-label pilot study of memantine in the treatment of compulsive buying
    Jon E Grant
    Department of Psychiatry, University of Minnesota, School of Medicine, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 24:119-26. 2012
  2. ncbi Understanding and treating kleptomania: new models and new treatments
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Isr J Psychiatry Relat Sci 43:81-7. 2006
  3. pmc Impulse control disorders: updated review of clinical characteristics and pharmacological management
    Liana Schreiber
    Department of Psychiatry, Ambulatory Research Center, University of Minnesota Medical Center Minneapolis, MN, USA
    Front Psychiatry 2:1. 2011
  4. doi Neurocognitive deficits associated with shoplifting in young adults
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, MN 55454, USA
    Compr Psychiatry 53:1049-55. 2012
  5. pmc Neurocognitive dysfunction in strategic and non-strategic gamblers
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Prog Neuropsychopharmacol Biol Psychiatry 38:336-40. 2012
  6. doi Prevalence, correlates, and comorbidity of DSM-IV obsessive-compulsive personality disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    J Psychiatr Res 46:469-75. 2012
  7. doi A cognitive comparison of pathological skin picking and trichotillomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    J Psychiatr Res 45:1634-8. 2011
  8. pmc Neuropsychological deficits associated with cannabis use in young adults
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, United States
    Drug Alcohol Depend 121:159-62. 2012
  9. ncbi Late-onset obsessive compulsive disorder: clinical characteristics and psychiatric comorbidity
    Jon E Grant
    Department of Psychiatry, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychiatry Res 152:21-7. 2007
  10. pmc Sexual orientation of men with pathological gambling: prevalence and psychiatric comorbidity in a treatment-seeking sample
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Compr Psychiatry 47:515-8. 2006

Research Grants

Detail Information

Publications108 found, 100 shown here

  1. ncbi Open-label pilot study of memantine in the treatment of compulsive buying
    Jon E Grant
    Department of Psychiatry, University of Minnesota, School of Medicine, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 24:119-26. 2012
    ..Memantine, an N-methyl-D-aspartate receptor antagonist, appears to reduce glutamate excitability and improve impulsive behaviors, suggesting it may help individuals with CB...
  2. ncbi Understanding and treating kleptomania: new models and new treatments
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Isr J Psychiatry Relat Sci 43:81-7. 2006
    ..Subtyping of individuals with kleptomania may be a useful way to better understand this behavior and decide on effective treatment interventions...
  3. pmc Impulse control disorders: updated review of clinical characteristics and pharmacological management
    Liana Schreiber
    Department of Psychiatry, Ambulatory Research Center, University of Minnesota Medical Center Minneapolis, MN, USA
    Front Psychiatry 2:1. 2011
    ..This article presents a brief overview about the clinical characteristics of ICDs and pharmacological treatment options for individuals with ICDs...
  4. doi Neurocognitive deficits associated with shoplifting in young adults
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, MN 55454, USA
    Compr Psychiatry 53:1049-55. 2012
    ..Shoplifting is a relatively common behavior in young adults, but the demographic and neuropsychological correlates of shoplifting remain poorly characterized in this context...
  5. pmc Neurocognitive dysfunction in strategic and non-strategic gamblers
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Prog Neuropsychopharmacol Biol Psychiatry 38:336-40. 2012
    ..Whether or not putative pathological gambling subtypes differ in terms of their clinical and cognitive profiles has received little attention...
  6. doi Prevalence, correlates, and comorbidity of DSM-IV obsessive-compulsive personality disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    J Psychiatr Res 46:469-75. 2012
    ..The results highlight the need for further research to identify common pathophysiological elements common to OCPD and associated disorders...
  7. doi A cognitive comparison of pathological skin picking and trichotillomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    J Psychiatr Res 45:1634-8. 2011
    ..The extent to which these disorders share a common cognitive phenotype, however, has yet to be examined. This study sought to compare inhibitory control processes in individuals with PSP or TTM...
  8. pmc Neuropsychological deficits associated with cannabis use in young adults
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, United States
    Drug Alcohol Depend 121:159-62. 2012
    ..It is unclear whether such impairment can occur in the absence of potential confounding influences of co-morbid axis-I disorders and use of other illicit substances...
  9. ncbi Late-onset obsessive compulsive disorder: clinical characteristics and psychiatric comorbidity
    Jon E Grant
    Department of Psychiatry, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychiatry Res 152:21-7. 2007
    ....
  10. pmc Sexual orientation of men with pathological gambling: prevalence and psychiatric comorbidity in a treatment-seeking sample
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Compr Psychiatry 47:515-8. 2006
    ..04). Psychiatric comorbidity and impairment are high in gay and bisexual men with PG. Research is needed to optimize patient care for gay and bisexual men with PG...
  11. ncbi Neuropsychological functioning in kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Behav Res Ther 45:1663-70. 2007
    ..693, p=0.004). As a group, subjects with kleptomania did not demonstrate deficits on neuropsychological testing. Greater kleptomania symptom severity, however, was correlated with impairment in executive functioning...
  12. doi Legal consequences of kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychiatr Q 80:251-9. 2009
    ..Kleptomania is associated with significant legal repercussions. The findings emphasize the need for rigorous treatment approaches to target kleptomania symptoms and prevent re-offending...
  13. ncbi The neurobiology of substance and behavioral addictions
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    CNS Spectr 11:924-30. 2006
    ....
  14. ncbi Sexual obsessions and clinical correlates in adults with obsessive-compulsive disorder
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, 55454, USA
    Compr Psychiatry 47:325-9. 2006
    ..These preliminary results suggest that sexual obsessions are fairly common among individuals with OCD and may be associated with important clinical characteristics...
  15. pmc Pathological skin picking in individuals with body dysmorphic disorder
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Gen Hosp Psychiatry 28:487-93. 2006
    ..The objective of this study was to examine the prevalence and clinical correlates of pathological skin picking (PSP) in a large sample of individuals with body dysmorphic disorder (BDD)...
  16. ncbi Multicenter investigation of the opioid antagonist nalmefene in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Am J Psychiatry 163:303-12. 2006
    ..The authors examined the efficacy and tolerability of the opioid antagonist nalmefene in the treatment of adults with pathological gambling...
  17. ncbi Update on pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Curr Psychiatry Rep 8:53-8. 2006
    ..Although PG is a disabling disorder that continues to represent a clinical challenge for the healthcare professional, our current knowledge of pharmacotherapy and psychosocial interventions offers potentially effective treatment options...
  18. pmc Pharmacological treatment of adolescent pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Int J Adolesc Med Health 22:129-38. 2010
    ....
  19. pmc Compulsive aspects of impulse-control disorders
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue Minneapolis, MN 55454, USA
    Psychiatr Clin North Am 29:539-51, x. 2006
    ..The construct of compulsivity as related to ICDs and OCD warrants additional investigation to identify the similarities and differences and to examine the implications for prevention and treatment strategies...
  20. ncbi Escitalopram treatment of pathological gambling with co-occurring anxiety: an open-label pilot study with double-blind discontinuation
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, Minnesota 55454, USA
    Int Clin Psychopharmacol 21:203-9. 2006
    ..Larger, longer, placebo-controlled, double-blind studies are needed to evaluate further the safety and tolerability of escitalopram in the treatment of PG and co-occurring anxiety...
  21. pmc Pathologic gambling and bankruptcy
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Compr Psychiatry 51:115-20. 2010
    ..Although prior studies have examined rates of bankruptcy in pathologic gambling (PG), there are only limited data regarding the clinical correlates of those with PG who declare bankruptcy because of gambling...
  22. doi A double-blind, placebo-controlled study of the opiate antagonist, naltrexone, in the treatment of kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Biol Psychiatry 65:600-6. 2009
    ..This study examined the efficacy and tolerability of the opioid antagonist naltrexone in adults with kleptomania who have urges to steal...
  23. ncbi N-acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: a pilot study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Biol Psychiatry 62:652-7. 2007
    ..N-acetyl cysteine (NAC), an amino acid, seems to restore extracellular glutamate concentration in the nucleus accumbens and therefore offers promise in reducing addictive behavior...
  24. ncbi Addicted to hair pulling? How an alternate model of trichotillomania may improve treatment outcome
    Jon E Grant
    Psychiatry Department, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Harv Rev Psychiatry 15:80-5. 2007
  25. pmc Relationship of nicotine dependence, subsyndromal and pathological gambling, and other psychiatric disorders: data from the National Epidemiologic Survey on Alcohol and Related Conditions
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 70:334-43. 2009
    ..Nicotine dependence frequently co-occurs with subsyndromal and pathological levels of gambling. The relationship of nicotine dependence, levels of gambling pathology, and other psychiatric disorders, however, is incompletely understood...
  26. pmc Clinical characteristics of trichotillomania with trichophagia
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Compr Psychiatry 49:579-84. 2008
    ..Little is known about trichophagia in individuals with trichotillomania. Although studies have mentioned the behavior, no previous studies have examined clinical correlates of trichophagia...
  27. ncbi N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Arch Gen Psychiatry 66:756-63. 2009
    ..N-acetylcysteine, an amino acid, seems to restore the extracellular glutamate concentration in the nucleus accumbens and, therefore, offers promise in the reduction of compulsive behavior...
  28. pmc Predicting response to opiate antagonists and placebo in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopharmacology (Berl) 200:521-7. 2008
    ..No studies have systematically examined predictors of medication treatment outcome in PG. Understanding clinical variables related to treatment outcome should help generate treatment algorithms for PG...
  29. ncbi Update on pathological skin picking
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Curr Psychiatry Rep 11:283-8. 2009
    ..Although the disorder is common, appropriate treatments for PSP are limited. Pharmacotherapeutic and certain cognitive-behavioral interventions have demonstrated promise in treating this disorder and need to be explored further...
  30. pmc Late-onset pathological gambling: clinical correlates and gender differences
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Psychiatr Res 43:380-7. 2009
    ..Late-onset PG is relatively common and has distinct clinical characteristics suggesting that this population might benefit from unique prevention and treatment strategies...
  31. ncbi A double-blind, placebo-controlled study of the opiate antagonist naltrexone in the treatment of pathological gambling urges
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    J Clin Psychiatry 69:783-9. 2008
    ..This study examined the efficacy and tolerability of the opioid antagonist naltrexone in adults with PG who have urges to gamble...
  32. pmc Gender-related differences in individuals seeking treatment for kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    CNS Spectr 13:235-45. 2008
    ..Few empirical investigations have been performed in kleptomania, particularly with respect to gender-related influences...
  33. ncbi Frontal white matter integrity in borderline personality disorder with self-injurious behavior
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, University of Minnesota, Minneapolis, MN, USA
    J Neuropsychiatry Clin Neurosci 19:383-90. 2007
    ..Women with borderline personality disorder-self-injurious behavior exhibit decreased white matter microstructural integrity in inferior frontal brain regions that may include components of orbito-frontal circuitry...
  34. doi A Structured Clinical Interview for Kleptomania (SCI-K): preliminary validity and reliability testing
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Int J Methods Psychiatr Res 15:83-94. 2006
    ..These findings require replication in larger groups, including non-psychiatric populations, to examine their generalizability...
  35. ncbi Clinical characteristics and psychiatric comorbidity of pyromania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 68:1717-22. 2007
    ..This study details the demographic and phenomenological features of individuals with DSM-IV lifetime pyromania...
  36. ncbi Impulse-control disorders in adolescent psychiatric inpatients: co-occurring disorders and sex differences
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 68:1584-92. 2007
    ..To examine in a sex-sensitive manner the frequencies, clinical correlates, and patterns of co-occurrence of impulse-control disorders in adolescent psychiatric inpatients...
  37. ncbi Lamotrigine treatment of pathologic skin picking: an open-label study
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 68:1384-91. 2007
    ..Although pathologic skin picking is a relatively common behavior, treatment data are limited. We hypothesized that lamotrigine would reduce the symptoms of pathologic skin picking...
  38. ncbi [Kleptomania: clinical characteristics and treatment]
    Jon E Grant
    Departmento de Psiquiatria, School of Medicine, University of Minnesota, Minnesota 55454, USA
    Rev Bras Psiquiatr 30:S11-5. 2008
    ..Despite its relatively long history, kleptomania remains poorly understood to the general public, clinicians, and sufferers...
  39. ncbi Examination of gender in pathologic grooming behaviors
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychiatr Q 78:259-67. 2007
    ..Further research is needed to validate our findings and identify whether treatments should be specially tailored differently for men and women with grooming disorders...
  40. ncbi Impulse control disorders in adults with obsessive compulsive disorder
    Jon E Grant
    Butler Hospital and the Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02906, USA
    J Psychiatr Res 40:494-501. 2006
    ..These preliminary results suggest that there is a low prevalence of ICDs among individuals with OCD, although certain ICDs (skin picking) appear to be more common...
  41. ncbi Clinical characteristics and psychiatric comorbidity in males with exhibitionism
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School and Butler Hospital, Providence, R I, USA
    J Clin Psychiatry 66:1367-71. 2005
    ..This study was constructed to detail the demographic and phenomenological features of males with exhibitionism...
  42. ncbi Comorbidity of impulse control disorders in pathological gamblers
    J E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454 1495, USA
    Acta Psychiatr Scand 108:203-7. 2003
    ..To investigate the rate of impulse control disorders among pathological gamblers and examine the relationship of comorbidity to gambling severity...
  43. ncbi Paroxetine treatment of pathological gambling: a multi-centre randomized controlled trial
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, Minnesota 55454 1495, USA
    Int Clin Psychopharmacol 18:243-9. 2003
    ..Paroxetine consistently demonstrated an advantage over placebo on the Clinical Global Impressions scale; however, a larger sample size may have registered significant differences...
  44. ncbi Advances in the pharmacological treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454 1495, USA
    J Gambl Stud 19:85-109. 2003
    ..We also discuss dosage strategies, the duration of treatment, issues surrounding medication compliance, and approaches to treatment-refractory pathological gambling, such as pharmacological and behavioral augmentation...
  45. ncbi Effectiveness of pharmacotherapy for pathological gambling: a chart review
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, Minnesota 55454 1495, USA
    Ann Clin Psychiatry 14:155-61. 2002
    ..Naltrexone, or augmentation of naltrexone with an SSRI, appears to be most effective in relieving gambling symptoms...
  46. doi Dronabinol, a cannabinoid agonist, reduces hair pulling in trichotillomania: a pilot study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopharmacology (Berl) 218:493-502. 2011
    ..Trichotillomania is characterized by repetitive pulling causing noticeable hair loss. Pharmacological treatment data for trichotillomania are limited...
  47. ncbi Parental bonding in pathological gambling disorder
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454 1495, USA
    Psychiatr Q 73:239-47. 2002
    ..These preliminary findings suggest that neglectful parenting appears to be associated with pathological gambling disorder...
  48. pmc Personality disorders in gay, lesbian, bisexual, and transgender chemically dependent patients
    Jon E Grant
    Department of Psychiatry, University of MinnesotaSchool of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Am J Addict 20:405-11. 2011
    ..6%), and avoidant (n = 71; 49.0%) personality disorders. Preliminary data suggest that there is a high prevalence of personality disorders in the GLBT population undergoing chemical dependency treatment. ..
  49. doi Nalmefene in the treatment of pathological gambling: multicentre, double-blind, placebo-controlled study
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Br J Psychiatry 197:330-1. 2010
    ..These findings suggest that medication dosing may be an important consideration in achieving symptom control...
  50. ncbi An open-label study of naltrexone in the treatment of kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis 55454 1495, USA
    J Clin Psychiatry 63:349-56. 2002
    ..The present study was designed to test the short-term efficacy and safety of naltrexone in the treatment of kleptomania...
  51. ncbi A case of kleptomania and compulsive sexual behavior treated with naltrexone
    J E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis 55454 1495, USA
    Ann Clin Psychiatry 13:229-31. 2001
    ..Discontinuation and rechallenge with the medication provides further support that improvement was due to naltrexone. Naltrexone in high doses show promise for the treatment of both kleptomania and compulsive sexual behavior...
  52. ncbi Body dysmorphic disorder in patients with anorexia nervosa: prevalence, clinical features, and delusionality of body image
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    Int J Eat Disord 32:291-300. 2002
    ..We hypothesized that body dysmorphic disorder would be underdiagnosed in patients with anorexia nervosa and that comorbidity with body dysmorphic disorder would result in greater overall dysfunction...
  53. ncbi Demographic and clinical features of 131 adult pathological gamblers
    J E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis 55454 1495, USA
    J Clin Psychiatry 62:957-62. 2001
    ..This study was constructed to detail the demographic and phenomenological features of pathological gamblers...
  54. ncbi Changes in psychiatric consultations over ten years
    J E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA
    Gen Hosp Psychiatry 23:261-5. 2001
    ..The 2000 patients appeared to have more severe psychiatric illness and to be more medically complicated. These findings have implications in the context of cost effective health care...
  55. ncbi Prevalence and clinical features of body dysmorphic disorder in adolescent and adult psychiatric inpatients
    J E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis 55454 1495, USA
    J Clin Psychiatry 62:517-22. 2001
    ..Because of the shame and humiliation that BDD patients suffer, we hypothesized that, unless specifically screened for at the time of admission, BDD would be underdiagnosed in psychiatric inpatients...
  56. pmc Imaginal desensitisation plus motivational interviewing for pathological gambling: randomised controlled trial
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Br J Psychiatry 195:266-7. 2009
    ..People who failed to respond to Gamblers Anonymous reported significantly greater reduction in pathological gambling symptoms following later assignment to IDMI. Abstinence was achieved by 63.6% during the acute IDMI treatment period...
  57. ncbi Adolescent kleptomania treated with naltrexone--a case report
    J E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis 55454, USA
    Eur Child Adolesc Psychiatry 11:92-5. 2002
    ..This report presents a case of an adolescent with kleptomania who responded to naltrexone. The clinical features of kleptomania are reviewed, as are available data on the treatment of this distressing and often disabling disorder...
  58. ncbi Perceived stress in kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, Minnesota 55454 1495, USA
    Psychiatr Q 74:251-8. 2003
    ..31, df = 15, p = .000). People with kleptomania have higher levels of perceived stress than people with MDD, and the perceived stress decreases as the kleptomania symptoms are treated...
  59. ncbi Dissociative symptoms in pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopathology 36:200-3. 2003
    ..The purpose of this investigation was to shed light on a possible link between dissociation and pathological gambling, a relatively common disorder whose phenomenology remains understudied...
  60. pmc A double-blind, placebo-controlled trial of lamotrigine for pathological skin picking: treatment efficacy and neurocognitive predictors of response
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    J Clin Psychopharmacol 30:396-403. 2010
    ..However, these neurocognitive data suggest that lamotrigine may be valuable in a subset of patients who exhibit relatively impaired cognitive flexibility...
  61. doi A clinical comparison of pathologic skin picking and obsessive-compulsive disorder
    Jon E Grant
    Department of Psychiatry, Ambulatory Research Center, University of Minnesota Medical Center, Minneapolis, MN 55454, USA
    Compr Psychiatry 51:347-52. 2010
    ..This study sought to examine the clinical similarities between PSP and OCD...
  62. pmc Recognizing and treating body dysmorphic disorder
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 17:205-10. 2005
    ..Body dysmorphic disorder (BDD) is a relatively common and often-disabling obsessive compulsive spectrum disorder that often goes unrecognized in clinical practice...
  63. doi A double-blind, placebo-controlled study of N-acetyl cysteine plus naltrexone for methamphetamine dependence
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Eur Neuropsychopharmacol 20:823-8. 2010
    ..The question of whether a larger, well-powered sample would have detected differences between NAC plus naltrexone and placebo deserves further examination...
  64. pmc Memantine shows promise in reducing gambling severity and cognitive inflexibility in pathological gambling: a pilot study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopharmacology (Berl) 212:603-12. 2010
    ..Memantine, an N-methyl D-aspartate receptor antagonist, appears to reduce glutamate excitability and improve impulsive decision making, suggesting it may help individuals with PG...
  65. pmc A 6-month follow-up of imaginal desensitization plus motivational interviewing in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 23:3-10. 2011
    ..This study sought to examine whether those benefits were maintained 6 months post-treatment...
  66. ncbi Tobacco use and pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 17:237-41. 2005
    ..An improved understanding of the relationship would be helpful in treating individuals with co-occurring pathological gambling and nicotine dependence...
  67. pmc Shopping problems among high school students
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Compr Psychiatry 52:247-52. 2011
    ..An assessment of adolescent shopping behavior along a continuum of severity and its relationship to other behaviors and health issues is incompletely understood...
  68. ncbi Impulse control disorders in adult psychiatric inpatients
    Jon E Grant
    Department of Psychiatry, University of Minnesota, 2450 Riverside Ave, Minneapolis, MN 55454
    Am J Psychiatry 162:2184-8. 2005
    ..The authors' goal was to examine the prevalence of impulse control disorders in psychiatric inpatients...
  69. pmc Stealing among high school students: prevalence and clinical correlates
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    J Am Acad Psychiatry Law 39:44-52. 2011
    ..Significant distress and loss of control over this behavior suggest that stealing often has significant associated morbidity...
  70. pmc Prevalence and correlates of fire-setting in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)
    Carlos Blanco
    Department of Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Box 69, New York, NY 10032, USA
    J Clin Psychiatry 71:1218-25. 2010
    ..To estimate the prevalence, sociodemographic correlates, comorbidity, and rates of mental health service utilization of fire-setters in the general population...
  71. ncbi Pharmacotherapy outcome in older pathological gamblers: a preliminary investigation
    Jon E Grant
    Department of Psychiatry and Human Behavior, Butler Hospital and Brown Medical School, 345 Blackstone Blvd, Providence, RI 02906, USA
    J Geriatr Psychiatry Neurol 17:9-12. 2004
    ..The present findings indicate that many older pathological gamblers respond to "off-label" use of pharmacotherapy. The present findings are preliminary. Further studies with larger samples are needed to confirm these findings...
  72. ncbi Characteristics of pathological gamblers with a problem gambling parent
    Liana Schreiber
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, Minnesota 55454, USA
    Am J Addict 18:462-9. 2009
    ..Treatment approaches may need to be tailored for specific problems secondary to gambling and gender issues based on the history of having a problem gambling parent...
  73. pmc Substance use disorders in individuals with body dysmorphic disorder
    Jon E Grant
    Butler Hospital and the Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02906, USA
    J Clin Psychiatry 66:309-16; quiz 404-5. 2005
    ..Little is known about substance use disorders (SUDs) in individuals with body dysmorphic disorder (BDD). Although studies have examined SUD comorbidity in BDD, no previous studies have examined clinical correlates of SUD comorbidity...
  74. ncbi Gender differences in pathological gamblers seeking medication treatment
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Ave, Minneapolis, MN 55454 1495, USA
    Compr Psychiatry 43:56-62. 2002
    ..There appear to be some gender differences in the clinical features of PGD, and these differences may have treatment implications...
  75. pmc Substance use disorders in an obsessive compulsive disorder clinical sample
    Maria C Mancebo
    Butler Hospital, Providence, RI 02906, USA
    J Anxiety Disord 23:429-35. 2009
    ..Individuals with a juvenile-onset of OCD or comorbid BPD may be especially vulnerable to SUDs. Further research is needed to identify risk factors for SUDs and to better understand their impact on OCD course...
  76. ncbi Preliminary validity and reliability testing of a structured clinical interview for pathological gambling
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Psychiatry Res 128:79-88. 2004
    ..The SCI-PG demonstrated excellent reliability and validity in diagnosing PG in subjects presenting with gambling problems. These findings require replication in other groups to examine their generalizability...
  77. ncbi Childhood-onset pathologic skin picking: clinical characteristics and psychiatric comorbidity
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Compr Psychiatry 48:388-93. 2007
    ....
  78. ncbi Characteristics of geriatric patients seeking medication treatment for pathologic gambling disorder
    J E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis 55454-1495, USA
    J Geriatr Psychiatry Neurol 14:125-9. 2001
    ..There appear to be some differences in the clinical features of PGD among geriatric subjects, and these differences may have treatment implications...
  79. doi Motor inhibition and cognitive flexibility in pathologic skin picking
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Prog Neuropsychopharmacol Biol Psychiatry 34:208-11. 2010
    ..This study sought to assess motor inhibitory control and aspects of cognitive flexibility in a sample of individuals with PSP...
  80. ncbi Impulse control disorders: clinical characteristics and pharmacological management
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital, Providence, Rhode Island 02906, USA
    Ann Clin Psychiatry 16:27-34. 2004
    ....
  81. ncbi Temperament and early environmental influences in kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis 55454 1495, USA
    Compr Psychiatry 43:223-8. 2002
    ..These findings suggest that an understanding of early parenting behavior and a dimensional approach to the personality of kleptomaniacs may offer insight into this disorder and provide clues to treatment strategies...
  82. pmc Correlates of occupational disability in a clinical sample of obsessive-compulsive disorder
    Maria C Mancebo
    Butler Hospital, Providence, RI 02906, USA
    Compr Psychiatry 49:43-50. 2008
    ..This study aimed to examine correlates of occupational disability in a large, clinical sample of individuals with a primary diagnosis of obsessive-compulsive disorder (OCD)...
  83. ncbi Clinical characteristics and associated psychopathology of 22 patients with kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454 1495, USA
    Compr Psychiatry 43:378-84. 2002
    ..We conclude that kleptomania is a distressing and disabling disorder associated with high rates of psychiatric comorbidity...
  84. ncbi Dissociative symptoms in kleptomania
    Jon E Grant
    Department of Psychiatry and Human Behavior, Butler Hospital Brown Medical School, 345 Blackstone Blvd, Providence, RI 02906, USA
    Psychol Rep 94:77-82. 2004
    ..There were no statistically significant differences by sex. Because kleptomania patients seeking treatment with medication may differ from others with kleptomania, further studies are needed...
  85. ncbi Pathological gambling. Current status and new treatments
    Suck Won Kim
    Department of Psychiatry, University of Minnesota Medical School, USA
    Minn Med 85:48-50, 52. 2002
    ..A brief clinical description of PGD is followed by a summary of published drug treatment outcomes and the basic principles of medication treatment in office practice...
  86. ncbi Double-blind naltrexone and placebo comparison study in the treatment of pathological gambling
    S W Kim
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, Minnesota 55454-1495, USA
    Biol Psychiatry 49:914-21. 2001
    ..CONCLUSIONS: Results suggest that naltrexone is effective in reducing the symptoms of pathologic gambling. Until further studies corroborate the present findings, our report should be interpreted cautiously...
  87. pmc A neurocognitive comparison of cognitive flexibility and response inhibition in gamblers with varying degrees of clinical severity
    B L Odlaug
    Department of Psychiatry, Ambulatory Research Center, University of Minnesota, Minneapolis, MN 55454, USA
    Psychol Med 41:2111-9. 2011
    ....
  88. ncbi Treatment of compulsive sexual behaviour with naltrexone and serotonin reuptake inhibitors: two case studies
    N C Raymond
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Int Clin Psychopharmacol 17:201-5. 2002
    ..Although more research is needed to determine the mechanism that leads to the excessive sexual behaviour in individuals with CSB, the present case reports suggest that naltrexone may be effective in treating some cases of CSB...
  89. ncbi Personality dimensions in pathological gambling disorder and obsessive-compulsive disorder
    S W Kim
    Department of Psychiatry, University of Minnesota School of Medicine, F256 2A West, 2450 Riverside Avenue, Minneapolis, MN 55454 1495, USA
    Psychiatry Res 104:205-12. 2001
    ..These results suggest that the personality dimensions of pathological gamblers may differ significantly from both those of OCD patients and normal controls...
  90. ncbi An open naltrexone treatment study in pathological gambling disorder
    S W Kim
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis 55454 1495, USA
    Int Clin Psychopharmacol 16:285-9. 2001
    ..The present findings provide evidence that naltrexone may be effective in the treatment of pathological gambling disorder. The present report is preliminary and controlled trials are needed to confirm these findings...
  91. ncbi Treatment of agitation and aggression in four demented patients using ECT
    J E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota 55454 1495, USA
    J ECT 17:205-9. 2001
    ..Four case studies are presented that show its efficacy in treating behavioral symptoms in demented patients. We suggest that ECT is beneficial in these potentially life-threatening behavioral disturbances...
  92. ncbi The psychopharmacology of pathological gambling
    S W Kim
    Department of Psychiatry, University of Minnesota, School of Medicine, Minneapolis, MN 55454-1495, USA
    Semin Clin Neuropsychiatry 6:184-94. 2001
    ..Finally, we discuss a research agenda to be addressed in future drug treatment studies in pathological gambling...
  93. ncbi Kleptomania: clinical characteristics and relationship to substance use disorders
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, 55454, USA
    Am J Drug Alcohol Abuse 36:291-5. 2010
    ..Although categorized as an impulse control disorder, kleptomania has many features in common with substance use disorders...
  94. ncbi A possible association of recurrent streptococcal infections and acute onset of obsessive-compulsive disorder
    Suck Won Kim
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, Minnesota, USA
    J Neuropsychiatry Clin Neurosci 16:252-60. 2004
    ..In this article, we review the microbial characteristics of GABHS and the subsequent immune responses to GABHS as a possible etiology of PANDAS...
  95. ncbi Trichotillomania and Pathologic Skin Picking: clinical comparison with an examination of comorbidity
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, Minnesota 55454, USA
    Ann Clin Psychiatry 20:57-63. 2008
    ..We sought to examine the similarities and differences between these three groups from a clinical viewpoint...
  96. ncbi Pathological gambling and mood disorders: clinical associations and treatment implications
    Suck Won Kim
    Department of Psychiatry, University of Minnesota Medical School, F282 2A West, 2450 Riverside Avenue, Minneapolis, 55454, USA
    J Affect Disord 92:109-16. 2006
    ..Traditionally, mood and gambling symptoms have been known to overlap. In the present review we attempt to examine the diagnostic associations and implications for treatment...
  97. pmc Naltrexone effect on physiological and subjective response to a cold pressor task
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, 7 170 Weaver Densford Hall, 308 Harvard St SE, Minneapolis, MN 55455, United States
    Biol Psychol 77:233-6. 2008
    ..No significant differences were found for other measures assessed. Further research is necessary to determine the subpopulations in which these effects are of greatest magnitude and the long term safety implications of these effects...
  98. ncbi N-acetyl cysteine in the treatment of grooming disorders
    Brian L Odlaug
    J Clin Psychopharmacol 27:227-9. 2007
  99. ncbi A double-blind placebo-controlled study of the efficacy and safety of paroxetine in the treatment of pathological gambling
    Suck Won Kim
    Department of Psychiatry, University of Minnesota, Minneapolis, USA
    J Clin Psychiatry 63:501-7. 2002
    ..This randomized, double-blind, placebo-controlled study investigated the efficacy and tolerability of paroxetine in the treatment of pathological gambling...
  100. pmc Medication management of pathological gambling
    Jon E Grant
    University of Minnesota Medical School, USA
    Minn Med 89:44-8. 2006
    ....
  101. ncbi SPECT imaging and treatment of pyromania
    Jon E Grant
    J Clin Psychiatry 67:998. 2006

Research Grants2

  1. Cognitive-Behavioral Therapy for Pathological Gambling
    Jon Grant; Fiscal Year: 2007
    ..This award would provide me with the necessary background for further studies in the treatment of pathological gambling and the training for an independent patient-oriented research career. ..