SUSAN MARIE GRAHAM

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi HIV-1 RNA may decline more slowly in semen than in blood following initiation of efavirenz-based antiretroviral therapy
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 7:e43086. 2012
  2. ncbi Antiretroviral treatment interruptions predict female genital shedding of genotypically resistant HIV-1 RNA
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, WA 98104 2499, USA
    J Acquir Immune Defic Syndr 60:511-8. 2012
  3. ncbi Post-prostatic massage fluid/urine as an alternative to semen for studying male genitourinary HIV-1 shedding
    Susan M Graham
    University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Sex Transm Infect 87:232-7. 2011
  4. ncbi Genital ulceration does not increase HIV-1 shedding in cervical or vaginal secretions of women taking antiretroviral therapy
    Susan M Graham
    University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Sex Transm Infect 87:114-7. 2011
  5. ncbi Antiretroviral adherence and development of drug resistance are the strongest predictors of genital HIV-1 shedding among women initiating treatment
    Susan M Graham
    University of Washington, Seattle, Washington 98104 2499, USA
    J Infect Dis 202:1538-42. 2010
  6. ncbi A systematic review of the quality of trials evaluating biomedical HIV prevention interventions shows that many lack power
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington, USA
    HIV Clin Trials 10:413-31. 2009
  7. ncbi Increased risk of genital ulcer disease in women during the first month after initiating antiretroviral therapy
    Susan M Graham
    Departments of Medicine, Epidemiology and Global Health, University of Washington, Seattle, WA 98104 2499, USA
    J Acquir Immune Defic Syndr 52:600-3. 2009
  8. ncbi A decrease in albumin in early SIV infection is related to viral pathogenicity
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington 98104, USA
    AIDS Res Hum Retroviruses 25:433-40. 2009
  9. ncbi A decrease in albumin in early HIV type 1 infection predicts subsequent disease progression
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington 98104, USA
    AIDS Res Hum Retroviruses 23:1197-200. 2007
  10. ncbi Higher pre-infection vitamin E levels are associated with higher mortality in HIV-1-infected Kenyan women: a prospective study
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    BMC Infect Dis 7:63. 2007

Research Grants

  1. Genital HIV-1 Shedding among Women Starting Second-Line Antiretroviral Therapy
    Susan Graham; Fiscal Year: 2007

Detail Information

Publications14

  1. ncbi HIV-1 RNA may decline more slowly in semen than in blood following initiation of efavirenz-based antiretroviral therapy
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 7:e43086. 2012
    ..Our objective was to study the time course and magnitude of seminal HIV-1 RNA decay after initiation of efavirenz-based ART among 13 antiretroviral-naïve Kenyan men...
  2. ncbi Antiretroviral treatment interruptions predict female genital shedding of genotypically resistant HIV-1 RNA
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, WA 98104 2499, USA
    J Acquir Immune Defic Syndr 60:511-8. 2012
    ..Our objective was to identify predictors of drug-resistant HIV-1 RNA in genital secretions after initiation of nonnucleoside reverse transcriptase inhibitor-based therapy...
  3. ncbi Post-prostatic massage fluid/urine as an alternative to semen for studying male genitourinary HIV-1 shedding
    Susan M Graham
    University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Sex Transm Infect 87:232-7. 2011
    ..Because semen collection is often impractical, the acceptability, feasibility and validity of post-prostatic massage fluid/urine (post-PMF/U) was evaluated for studying male genitourinary HIV-1 shedding...
  4. ncbi Genital ulceration does not increase HIV-1 shedding in cervical or vaginal secretions of women taking antiretroviral therapy
    Susan M Graham
    University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Sex Transm Infect 87:114-7. 2011
    ..The effect of GUD on HIV-1 shedding among ART-treated women is not known. The objective of this study was to test the hypothesis that genital ulcerations increase genital HIV-1-RNA shedding in women receiving ART...
  5. ncbi Antiretroviral adherence and development of drug resistance are the strongest predictors of genital HIV-1 shedding among women initiating treatment
    Susan M Graham
    University of Washington, Seattle, Washington 98104 2499, USA
    J Infect Dis 202:1538-42. 2010
    ..04). These results emphasize the importance of adherence to optimize the potential benefits of ART for reducing HIV-1 transmission risk...
  6. ncbi A systematic review of the quality of trials evaluating biomedical HIV prevention interventions shows that many lack power
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington, USA
    HIV Clin Trials 10:413-31. 2009
    ..We aimed to identify, describe, and evaluate the quality of RCTs studying biomedical interventions to prevent HIV acquisition by sexual transmission...
  7. ncbi Increased risk of genital ulcer disease in women during the first month after initiating antiretroviral therapy
    Susan M Graham
    Departments of Medicine, Epidemiology and Global Health, University of Washington, Seattle, WA 98104 2499, USA
    J Acquir Immune Defic Syndr 52:600-3. 2009
    ..To better define this risk, we monitored 134 women at ART initiation and monthly thereafter...
  8. ncbi A decrease in albumin in early SIV infection is related to viral pathogenicity
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington 98104, USA
    AIDS Res Hum Retroviruses 25:433-40. 2009
    ..These results suggest that both early and late events in SIV pathogenesis are influenced by properties of the infecting viral strain...
  9. ncbi A decrease in albumin in early HIV type 1 infection predicts subsequent disease progression
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington 98104, USA
    AIDS Res Hum Retroviruses 23:1197-200. 2007
    ..0, p = 0.008). Trends for an increased risk of mortality were also seen. A greater decrease in albumin levels accompanying HIV-1 acquisition may be a marker for changes in early infection associated with more rapid disease progression...
  10. ncbi Higher pre-infection vitamin E levels are associated with higher mortality in HIV-1-infected Kenyan women: a prospective study
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    BMC Infect Dis 7:63. 2007
    ..However, vitamin E supplementation has also been reported to increase CCR5 expression, which could increase HIV-1 replication. We hypothesized that vitamin E levels at HIV-1 acquisition may influence disease progression...
  11. ncbi Initiation of antiretroviral therapy leads to a rapid decline in cervical and vaginal HIV-1 shedding
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington, USA
    AIDS 21:501-7. 2007
    ..Antiretroviral therapy (ART) may decrease HIV-1 infectivity in women by reducing genital HIV-1 shedding...
  12. ncbi Prospective study of vaginal bacterial flora and other risk factors for vulvovaginal candidiasis
    R Scott McClelland
    Department of Medicine, University of Washington, Seattle, WA 98104, USA
    J Infect Dis 199:1883-90. 2009
    ..Our objective was to determine the relationship between vaginal bacterial flora and VVC...
  13. ncbi Treatment with antiretroviral therapy is not associated with increased sexual risk behavior in Kenyan female sex workers
    R Scott McClelland
    Department of Medicine, University of Washington, Seattle, USA
    AIDS 24:891-7. 2010
    ..The objective of this study was to test the hypothesis that sexual risk behavior would increase following initiation of antiretroviral therapy (ART) in Kenyan female sex workers (FSWs)...
  14. ncbi A prospective study of risk factors for bacterial vaginosis in HIV-1-seronegative African women
    R Scott McClelland
    Department of Medicine, University of Washington, Seattle, WA 98104, USA
    Sex Transm Dis 35:617-23. 2008
    ..Bacterial vaginosis (BV) is common and has been associated with increased HIV-1 susceptibility. The objective of this study was to identify risk factors for BV in African women at high risk for acquiring HIV-1...

Research Grants2

  1. Genital HIV-1 Shedding among Women Starting Second-Line Antiretroviral Therapy
    Susan Graham; Fiscal Year: 2007
    ..As HIV therapy is scaled up, research on drug resistance and the success of second-line treatment is crucial, and Dr. Graham is poised to make an important contribution in this area.. ..