Brian B Graham

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc Significant intrapulmonary Schistosoma egg antigens are not present in schistosomiasis-associated pulmonary hypertension
    Brian B Graham
    Department of Medicine, Program in Translational Lung Research, University of Colorado Denver, Denver, CO, USA
    Pulm Circ 1:456-61. 2011
  2. pmc Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling
    Brian B Graham
    Program in Translational Lung Research, Pulmonary and Critical Care Medicine, University of Colorado, Denver, Colorado, USA
    Am J Pathol 177:1549-61. 2010
  3. ncbi request reprint Schistosomiasis-associated pulmonary hypertension: pulmonary vascular disease: the global perspective
    Brian B Graham
    Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado at Denver, Aurora, CO 80045, USA
    Chest 137:20S-29S. 2010
  4. ncbi request reprint Pathology of pulmonary hypertension
    Rubin M Tuder
    Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, 12700 East 19th Avenue, Research Complex 2, room 9001, Aurora, CO 80045, USA Electronic address
    Clin Chest Med 34:639-50. 2013
  5. pmc Cigarette smoke triggers code red: p21CIP1/WAF1/SDI1 switches on danger responses in the lung
    Rubin M Tuder
    Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado Denver, School of Medicine, 4200 East 9th Avenue, Campus Box C272, Denver, CO 80262, USA
    Am J Respir Cell Mol Biol 39:1-6. 2008
  6. pmc TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation
    Valeria M Borges
    Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA
    Am J Physiol Lung Cell Mol Physiol 297:L586-95. 2009
  7. pmc Targeting energetic metabolism: a new frontier in the pathogenesis and treatment of pulmonary hypertension
    Rubin M Tuder
    Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, USA
    Am J Respir Crit Care Med 185:260-6. 2012

Collaborators

Detail Information

Publications7

  1. pmc Significant intrapulmonary Schistosoma egg antigens are not present in schistosomiasis-associated pulmonary hypertension
    Brian B Graham
    Department of Medicine, Program in Translational Lung Research, University of Colorado Denver, Denver, CO, USA
    Pulm Circ 1:456-61. 2011
    ..This suggests that retained and persistent parasite proteins are not contributing to a localized immune response in the pathogenesis of this disease...
  2. pmc Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling
    Brian B Graham
    Program in Translational Lung Research, Pulmonary and Critical Care Medicine, University of Colorado, Denver, Colorado, USA
    Am J Pathol 177:1549-61. 2010
    ..Our data indicate that experimental schistosomiasis causes PH and potentially relies on up-regulated IL-13 signaling...
  3. ncbi request reprint Schistosomiasis-associated pulmonary hypertension: pulmonary vascular disease: the global perspective
    Brian B Graham
    Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado at Denver, Aurora, CO 80045, USA
    Chest 137:20S-29S. 2010
    ..Further research is needed into the pathogenic mechanism by which this parasitic infection results in pulmonary vascular remodeling and PH, which also may be informative regarding the etiology of other types of PH...
  4. ncbi request reprint Pathology of pulmonary hypertension
    Rubin M Tuder
    Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, 12700 East 19th Avenue, Research Complex 2, room 9001, Aurora, CO 80045, USA Electronic address
    Clin Chest Med 34:639-50. 2013
    ..There was correlation between perivascular inflammation, remodeling, and hemodynamics. This article summarizes the pathologic features of the normal and abnormal pulmonary circulation, and correlations with animal models. ..
  5. pmc Cigarette smoke triggers code red: p21CIP1/WAF1/SDI1 switches on danger responses in the lung
    Rubin M Tuder
    Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado Denver, School of Medicine, 4200 East 9th Avenue, Campus Box C272, Denver, CO 80262, USA
    Am J Respir Cell Mol Biol 39:1-6. 2008
    ..Molecular switches, ontologically designed for the protection of the host, are now hijacked by injurious stresses (such as cigarette smoke), leading to organ damage...
  6. pmc TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation
    Valeria M Borges
    Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA
    Am J Physiol Lung Cell Mol Physiol 297:L586-95. 2009
    ..These findings suggest that the presence of TNFalpha in the lung can alter the response of phagocytes to apoptotic cells leading to inflammatory cell recruitment and proinflammatory mediator production...
  7. pmc Targeting energetic metabolism: a new frontier in the pathogenesis and treatment of pulmonary hypertension
    Rubin M Tuder
    Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, USA
    Am J Respir Crit Care Med 185:260-6. 2012
    ..These investigations have led to novel approaches in the diagnosis and therapy of pulmonary hypertension...