Richard H Gracely

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint Evoked pain measures in fibromyalgia
    Richard H Gracely
    Department of Medicine, University of Michigan Health System, Ann Arbor VAMC, Ann Arbor, MI 48109 0483, USA
    Best Pract Res Clin Rheumatol 17:593-609. 2003
  2. ncbi request reprint Comparison of clinical and evoked pain measures in fibromyalgia
    Richard E Harris
    Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan 48106, USA
    J Pain 7:521-7. 2006
  3. ncbi request reprint Cerebrospinal fluid corticotropin-releasing factor concentration is associated with pain but not fatigue symptoms in patients with fibromyalgia
    Samuel A McLean
    Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
    Neuropsychopharmacology 31:2776-82. 2006
  4. pmc Traditional Chinese acupuncture and placebo (sham) acupuncture are differentiated by their effects on mu-opioid receptors (MORs)
    Richard E Harris
    Department of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 47:1077-85. 2009
  5. doi request reprint Comorbid somatic symptoms and functional status in patients with fibromyalgia and chronic fatigue syndrome: sensory amplification as a common mechanism
    Michael E Geisser
    Chronic Pain and Fatigue Research Center, Dept of Internal Medicine, Div of Rheumatology, Univ of Michigan, Ann Arbor, MI 48108, USA
    Psychosomatics 49:235-42. 2008
  6. ncbi request reprint Evidence of augmented central pain processing in idiopathic chronic low back pain
    Thorsten Giesecke
    University of Michigan, Ann Arbor, MI 48106, USA
    Arthritis Rheum 50:613-23. 2004
  7. ncbi request reprint The association between experimental and clinical pain measures among persons with fibromyalgia and chronic fatigue syndrome
    Michael E Geisser
    Chronic Pain and Fatigue Research Center, Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI, USA
    Eur J Pain 11:202-7. 2007
  8. ncbi request reprint Treatment of fibromyalgia with formula acupuncture: investigation of needle placement, needle stimulation, and treatment frequency
    Richard E Harris
    Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI 48106, USA
    J Altern Complement Med 11:663-71. 2005
  9. ncbi request reprint Characterization and consequences of pain variability in individuals with fibromyalgia
    Richard E Harris
    Chronic Pain and Fatigue Research Center, University of Michigan Medical Center, 24 Frank Lloyd Wright Drive, PO Box 385, Ann Arbor, MI 48106, USA
    Arthritis Rheum 52:3670-4. 2005
  10. doi request reprint A psychophysical study of auditory and pressure sensitivity in patients with fibromyalgia and healthy controls
    Michael E Geisser
    Chronic Pain and Fatigue Research Center, Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan 48108, USA
    J Pain 9:417-22. 2008

Detail Information

Publications43

  1. ncbi request reprint Evoked pain measures in fibromyalgia
    Richard H Gracely
    Department of Medicine, University of Michigan Health System, Ann Arbor VAMC, Ann Arbor, MI 48109 0483, USA
    Best Pract Res Clin Rheumatol 17:593-609. 2003
    ....
  2. ncbi request reprint Comparison of clinical and evoked pain measures in fibromyalgia
    Richard E Harris
    Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan 48106, USA
    J Pain 7:521-7. 2006
    ..05). Pain sensitivity as assessed by random paradigms was associated with improvements in clinical FM pain. Sophisticated pain testing paradigms might be responsive to change in clinical trials...
  3. ncbi request reprint Cerebrospinal fluid corticotropin-releasing factor concentration is associated with pain but not fatigue symptoms in patients with fibromyalgia
    Samuel A McLean
    Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
    Neuropsychopharmacology 31:2776-82. 2006
    ..Further studies are needed to better understand the nature of the association between CSF CRF and pain symptoms in FM...
  4. pmc Traditional Chinese acupuncture and placebo (sham) acupuncture are differentiated by their effects on mu-opioid receptors (MORs)
    Richard E Harris
    Department of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 47:1077-85. 2009
    ..These findings suggest that divergent MOR processes may mediate clinically relevant analgesic effects for acupuncture and sham acupuncture...
  5. doi request reprint Comorbid somatic symptoms and functional status in patients with fibromyalgia and chronic fatigue syndrome: sensory amplification as a common mechanism
    Michael E Geisser
    Chronic Pain and Fatigue Research Center, Dept of Internal Medicine, Div of Rheumatology, Univ of Michigan, Ann Arbor, MI 48108, USA
    Psychosomatics 49:235-42. 2008
    ..Somatic symptoms are common in conditions such as fibromyalgia (FM) and chronic fatigue syndrome (CFS)...
  6. ncbi request reprint Evidence of augmented central pain processing in idiopathic chronic low back pain
    Thorsten Giesecke
    University of Michigan, Ann Arbor, MI 48106, USA
    Arthritis Rheum 50:613-23. 2004
    ..We compared the results of both of these methods as applied to patients with idiopathic CLBP (n = 11), patients with widespread pain (fibromyalgia; n = 16), and healthy control subjects (n = 11)...
  7. ncbi request reprint The association between experimental and clinical pain measures among persons with fibromyalgia and chronic fatigue syndrome
    Michael E Geisser
    Chronic Pain and Fatigue Research Center, Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI, USA
    Eur J Pain 11:202-7. 2007
    ..These findings merit consideration when designing experimental studies of clinical pain associated with FM and CFS...
  8. ncbi request reprint Treatment of fibromyalgia with formula acupuncture: investigation of needle placement, needle stimulation, and treatment frequency
    Richard E Harris
    Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI 48106, USA
    J Altern Complement Med 11:663-71. 2005
    ..DESIGN/SETTINGS/SUBJECTS: A single-site, single-blind, randomized trial of 114 participants diagnosed with fibromyalgia for at least 1 year was performed...
  9. ncbi request reprint Characterization and consequences of pain variability in individuals with fibromyalgia
    Richard E Harris
    Chronic Pain and Fatigue Research Center, University of Michigan Medical Center, 24 Frank Lloyd Wright Drive, PO Box 385, Ann Arbor, MI 48106, USA
    Arthritis Rheum 52:3670-4. 2005
    ..We used electronic assessment data derived from a study of patients with fibromyalgia (FM) to examine variability of pain over time and to investigate the implications of pain fluctuation in the context of a clinical trial...
  10. doi request reprint A psychophysical study of auditory and pressure sensitivity in patients with fibromyalgia and healthy controls
    Michael E Geisser
    Chronic Pain and Fatigue Research Center, Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan 48108, USA
    J Pain 9:417-22. 2008
    ..Further research is needed to examine the neural substrates associated with this abnormality and its role in the etiology and maintenance of FM...
  11. doi request reprint Dynamic levels of glutamate within the insula are associated with improvements in multiple pain domains in fibromyalgia
    Richard E Harris
    University of Michigan, Chronic Pain and Fatigue Research Center, Ann Arbor, MI 48106, USA
    Arthritis Rheum 58:903-7. 2008
    ..This study was carried out to investigate the relationship between changing levels of Glu within the insula and changes in multiple pain domains in patients with FM...
  12. pmc Augmented central pain processing in vulvodynia
    Johnson P Hampson
    Chronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan 48106, USA
    J Pain 14:579-89. 2013
    ..Moreover, differing central activity between VVD subgroups suggests heterogeneous pathologies within this diagnosis...
  13. ncbi request reprint Momentary relationship between cortisol secretion and symptoms in patients with fibromyalgia
    Samuel A McLean
    Chronic Pain and Fatigue Research Center, University of Michigan Medical Center, 24 Frank Lloyd Wright Drive, PO Box 385, Ann Arbor, MI 48106, USA
    Arthritis Rheum 52:3660-9. 2005
    ....
  14. ncbi request reprint The relationship between depression, clinical pain, and experimental pain in a chronic pain cohort
    Thorsten Giesecke
    University of Michigan, Ann Arbor, USA
    Arthritis Rheum 52:1577-84. 2005
    ..This study evaluated the effect of symptoms of depression and/or clinically diagnosed major depressive disorder (MDD) on pain processing in patients with fibromyalgia (FM)...
  15. ncbi request reprint Quantitative sensory testing in vulvodynia patients and increased peripheral pressure pain sensitivity
    Jutta Giesecke
    Chronic Pain and Fatigue Research Program, Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan 48109 0708, USA
    Obstet Gynecol 104:126-33. 2004
    ..To assess both regional (vulvar) and overall (generalized) pain sensitivity in women with vulvodynia to determine whether both are increased, suggestive of altered central pain processing...
  16. ncbi request reprint Pain assessment in patients with fibromyalgia syndrome: a consideration of methods for clinical trials
    David A Williams
    Department of Medicine, Division of Rheumatology, University of Michigan, Ann Arbor 48106, USA
    Clin J Pain 20:348-56. 2004
    ..Baseline characteristics, characteristics over time, and compliance were evaluated for each of the methods...
  17. ncbi request reprint Decreased central mu-opioid receptor availability in fibromyalgia
    Richard E Harris
    Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan 48109, USA
    J Neurosci 27:10000-6. 2007
    ..These findings indicate altered endogenous opioid analgesic activity in FM and suggest a possible reason for why exogenous opiates appear to have reduced efficacy in this population...
  18. pmc Biology and therapy of fibromyalgia. Functional magnetic resonance imaging findings in fibromyalgia
    David A Williams
    Chronic Pain and Fatigue Research Center, Department of Internal Medicine, Division of Rheumatology, University of Michigan Health System, University of Michigan, Ann Arbor, MI, USA
    Arthritis Res Ther 8:224. 2006
    ..This article provides an overview of the nociceptive system as it functions normally, reviews functional brain imaging methods, and integrates the existing literature utilizing fMRI to study central pain mechanisms in fibromyalgia...
  19. ncbi request reprint Effect of test order on sensitivity in vulvodynia
    Barbara D Reed
    Department of Family Medicine, Chronic Pain and Fatigue Research Program, University of Michigan, Ann Arbor 48109 0708, USA
    J Reprod Med 52:199-206. 2007
    ..To assess the effect of order of sensitivity testing at the vulva and thumb on the sensitivity determined at the second site tested among women with and without vulvodynia...
  20. ncbi request reprint Knee pain and radiographic osteoarthritis interact in the prediction of levels of self-reported disability
    David A Williams
    The University of Michigan, Ann Arbor, MI 48106, USA
    Arthritis Rheum 51:558-61. 2004
    ..To determine predictors of disability depending on whether joint deformity and pain reporting exist independently or concurrently...
  21. ncbi request reprint Subgrouping of fibromyalgia patients on the basis of pressure-pain thresholds and psychological factors
    Thorsten Giesecke
    University of Michigan, Ann Arbor, USA
    Arthritis Rheum 48:2916-22. 2003
    ..In this study, we attempt to identify patient subsets by incorporating these features as well as the degree of hyperalgesia/tenderness, which is a key neurobiologic feature of this illness...
  22. pmc Cough, pain and dyspnoea: similarities and differences
    Richard H Gracely
    Department of Medicine, University of Michigan Health System, VA Ann Arbor Healthcare System, Ann Arbor, MI 48106, USA
    Pulm Pharmacol Ther 20:433-7. 2007
    ..We briefly review here the afferent and central pathways and psychophysics of pain, dyspnoea and urge to cough...
  23. ncbi request reprint When it's hard to breathe, maybe pain doesn't matter. Focus on "Dyspnea as a noxious sensation: inspiratory threshold loading may trigger diffuse noxious inhibitory controls in humans"
    Robert B Banzett
    J Neurophysiol 97:959-60. 2007
  24. ncbi request reprint A pain psychologist's view of tenderness in fibromyalgia
    Richard H Gracely
    J Rheumatol 34:912-3. 2007
  25. ncbi request reprint Functional magnetic resonance imaging evidence of augmented pain processing in fibromyalgia
    Richard H Gracely
    National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, USA
    Arthritis Rheum 46:1333-43. 2002
    ....
  26. doi request reprint Intraoral measurement of tactile and filament-prick pain threshold using shortened Semmes-Weinstein monofilaments
    Osamu Komiyama
    Department of Clinical Oral Physiology, Nihon University School of Dentistry at Matsudo, 2 870 1 Sakaecho nishi, Matsudo, Chiba, Japan
    Clin J Pain 24:16-21. 2008
    ....
  27. ncbi request reprint Using fMRI to dissociate sensory encoding from cognitive evaluation of heat pain intensity
    Jian Kong
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Hum Brain Mapp 27:715-21. 2006
    ..We hypothesize that these two regions play a crucial role in bridging the encoding of pain sensation and the cognitive processing of sensory input...
  28. ncbi request reprint Sex effects on heart rate variability in fibromyalgia and Gulf War illness
    Phyllis K Stein
    Washington University School of Medicine, St Louis, MO 63108, USA
    Arthritis Rheum 51:700-8. 2004
    ..To investigate autonomic abnormalities in male and female fibromyalgia (FM) and Gulf War illness (GWI) patients by comparing heart rate variability (HRV) with that of age- and sex-matched healthy controls...
  29. ncbi request reprint What do tender points measure? Influence of distress on 4 measures of tenderness
    Frank Petzke
    Chronic Pain and Fatigue Research Center, Georgetown University Medical Center, Washington, DC, USA
    J Rheumatol 30:567-74. 2003
    ..To examine the relationship between current pain, distress, and ascending and random measures of tenderness...
  30. ncbi request reprint Is seeing believing? Functional imaging of hysterical anesthesia
    Richard H Gracely
    Neurology 60:1410-1. 2003
  31. ncbi request reprint Visual analog pain scores and the need for analgesia
    Samuel A McLean
    Acad Emerg Med 10:1012-3; author reply 1013. 2003
  32. ncbi request reprint Increased pain sensitivity in fibromyalgia: effects of stimulus type and mode of presentation
    Frank Petzke
    Department of Anesthesiology, University of Cologne, Cologne, Germany
    Pain 105:403-13. 2003
    ..The increased sensitivity to both pressure and thermal stimuli for threshold and suprathreshold stimuli in FM patients is consistent with central augmentation of pain processing...
  33. ncbi request reprint Comparative study of electronic vs. paper VAS ratings: a randomized, crossover trial using healthy volunteers
    Robert N Jamison
    Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Pain 99:341-7. 2002
    ..Multivariate analyses showed equivalent stimuli to be rated much the same whether entered on paper VAS or PTC touch screen VAS (P < 0.0001). Support was found for the validity of the computer version of the VAS scale...
  34. ncbi request reprint Increased systemic catecholamines in complex regional pain syndrome and relationship to psychological factors: a pilot study
    R Norman Harden
    Rehabilitation Institute of Chicago, Center for Pain Studies, 446 E Ontario, Ste 1011, Chicago, IL 60611, USA
    Anesth Analg 99:1478-85; table of contents. 2004
    ..Definitive studies are needed to examine these hypotheses in detail...
  35. ncbi request reprint Psychophysical outcomes from a randomized pilot study of manual, electro, and sham acupuncture treatment on experimentally induced thermal pain
    Jian Kong
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    J Pain 6:55-64. 2005
    ..This suggests that attributes of the deqi sensation may be useful clinical indicators of effective treatment...
  36. ncbi request reprint Ambulatory monitoring of physical activity and symptoms in fibromyalgia and chronic fatigue syndrome
    Willem J Kop
    Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
    Arthritis Rheum 52:296-303. 2005
    ....
  37. ncbi request reprint Differences in unpleasantness induced by experimental pressure pain between patients with fibromyalgia and healthy controls
    Frank Petzke
    Department of Anesthesiology of the University of Cologne, Germany
    Eur J Pain 9:325-35. 2005
    ..Clinical pain in patients with FM was perceived to be more unpleasant than the evoked pain stimuli. These results are consistent with the concept that chronic pain may reduce the relative unpleasantness of evoked pain sensations...
  38. ncbi request reprint Efficacy of milnacipran in patients with fibromyalgia
    R Michael Gendreau
    Cypress Biosciences, 4350 Executive Drive, San Diego, CA 92121, USA
    J Rheumatol 32:1975-85. 2005
    ..Milnacipran, a nontricyclic compound that inhibits the reuptake of both serotonin and norepinephrine, may provide many of the beneficial effects of TCA with a superior side effect profile...
  39. ncbi request reprint Effect of dexamethasone and dipyrone on lingual and inferior alveolar nerve hypersensitivity following third molar extractions: preliminary report
    Robert P Barron
    Department of Oral Medicine, Hebrew University School of Dental Medicine, Hadassah Medical Center, Jerusalem, Israel
    J Orofac Pain 18:62-8. 2004
    ..To study the effect of dexamethazone and dipyrone on sensory changes in the innervation territories of the inferior alveolar, infraorbital, and lingual nerves caused by third molar extractions...
  40. ncbi request reprint Quantitative sensory testing in trigeminal nerve damage assessment
    Eli Eliav
    UMDNJ New Jersey Dental School Newark, New Jersey 07, USA
    J Orofac Pain 18:339-44. 2004
    ..In this article specific clinical uses of QST are described and its clinical applicability is demonstrated. Future studies should be directed at exploring the use of QST in the diagnosis and classification of further nerve pathologies...
  41. ncbi request reprint Facial arthralgia and myalgia: can they be differentiated by trigeminal sensory assessment?
    Eli Eliav
    Department of Oral Diagnosis Oral Medicine and Radiology, Hadassah Faculty of Dental Medicine, The Hebrew University, P O Box 12272, Jerusalem 91120, Israel
    Pain 104:481-90. 2003
    ..In patients with muscle-related facial pain there was significant elevation of the electrical detection threshold in the AUT region...
  42. ncbi request reprint Stability and reliability of detection thresholds for human A-Beta and A-delta sensory afferents determined by cutaneous electrical stimulation
    Christine N Sang
    Department of Anesthesia, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Pain Symptom Manage 25:64-73. 2003
    ..0 is uncommon. We propose that, in the presence of mechanical allodynia, a pain threshold/detection threshold of less than 2.0 suggests that altered central nervous system processing of Abeta input may contribute to allodynia...
  43. ncbi request reprint Periaqueductal gray-evoked dorsal root reflex is frequency dependent
    Yuan Bo Peng
    Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, 20892 4410, Bethesda, MD, USA
    Brain Res 976:217-26. 2003
    ..Transection at the thoracic spinal level completely eliminated PAG-induced DRRs. In conclusion, both PAG and peripheral stimulation produced DRRs in a frequency dependent manner. Stimulus intensity has no significant effect on DRRs...