Anitha P Govind
Affiliation: University of Chicago
- Up-regulation of nicotinic receptors by nicotine varies with receptor subtypeHeather Walsh
Department of Neurobiology, University of Chicago, Chicago, IL 60637, USA
J Biol Chem 283:6022-32. 2008....
- Nicotine-induced upregulation of nicotinic receptors: underlying mechanisms and relevance to nicotine addictionAnitha P Govind
Department of Neurobiology, University of Chicago, Abbot Hall 402 MC0926, Chicago, IL 60637, USA
Biochem Pharmacol 78:756-65. 2009..In this commentary, we review how nicotinic acetylcholine receptors (nAChRs) are upregulated by nicotine exposure, the potential posttranslational events that appear to cause it and how upregulation is linked to nicotine addiction...
- Intermittent nicotine exposure upregulates nAChRs in VTA dopamine neurons and sensitises locomotor responding to the drugLorinda K Baker
Department of Psychiatry and Behavioral Neuroscience, The University of Chicago, Chicago, IL, USA
Eur J Neurosci 37:1004-11. 2013..Thus, intermittent activation and upregulation by nicotine of nAChRs in DA neurons in the VTA may contribute to the development of behavioral sensitisation and increased liability for nicotine addiction...
- Nicotine-induced upregulation of native neuronal nicotinic receptors is caused by multiple mechanismsAnitha P Govind
Department of Neurobiology, University of Chicago, Chicago, Illinois 60637, USA
J Neurosci 32:2227-38. 2012..We conclude that nicotine-induced upregulation is composed of multiple processes occurring at different rates with different underlying causes...