Research Topics
Genomes and GenesSpecies | Pierre Antoine GourraudSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Linkage disequilibrium organization of the human KIR superlocus: implications for KIR data analysesPierre Antoine Gourraud
Department of Neurology, University of California, 513 Parnassus Avenue, San Francisco, CA 94143, USA
Immunogenetics 62:729-40. 2010..The present study provides a rationale for analyzing associations of KIR polymorphisms by taking into account the complex LD structure of the KIR region...
Why statistics matter: limited inter-rater agreement prevents using the psoriasis area and severity index as a unique determinant of therapeutic decision in psoriasisPierre Antoine Gourraud
Department of Neurology, UCSF School of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
J Invest Dermatol 132:2171-5. 2012..The ICC is preferable to the commonly used statistics (r and ρ) for assessing the inter-rater agreement reliability of asymmetrically distributed scores such as the PASI...
Standard methods for the management of immunogenetic dataPierre Antoine Gourraud
Department of Neurology, University of California, San Francisco, CA, USA
Methods Mol Biol 882:197-213. 2012....
The role of human leukocyte antigen matching in the development of multiethnic "haplobank" of induced pluripotent stem cell linesPierre Antoine Gourraud
Department of Neurology, University of California San Francisco School of Medicine, San Francisco, California, USA
Stem Cells 30:180-6. 2012..The constitution of a haplobank of iPSC lines is achievable through a large-scale concerted worldwide collaboration...
When is the absence of evidence, evidence of absence? Use of equivalence-based analyses in genetic epidemiology and a conclusion for the KIF1B rs10492972*C allelic association in multiple sclerosisPierre Antoine Gourraud
Department of Neurology, School of Medicine, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143 0435, USA
Genet Epidemiol 35:568-71. 2011..The data gathered for KIF1B in MS also underscore the need for very large sample sizes with the appropriate equivalence statistical methods in order to exclude reported false-positive results...
Refining the association of MHC with multiple sclerosis in African AmericansJoseph P McElroy
Department of Neurology, University of California, San Francisco, CA 94143, USA
Hum Mol Genet 19:3080-8. 2010....
Aggregation of multiple sclerosis genetic risk variants in multiple and single case familiesPierre Antoine Gourraud
Department of Neurology, School of Medicine, University of California at San Francisco, San Francisco, CA, USA
Ann Neurol 69:65-74. 2011..We aimed at investigating the aggregation of genetic MS risk markers in individuals by comparing multiple- and single-case families...
Analytical methods for disease association studies with immunogenetic dataJill A Hollenbach
Center for Genetics, Children s Hospital and Research Center Oakland, Oakland, CA, USA
Methods Mol Biol 882:245-66. 2012..case-control vs. family data) as well as the specific research hypotheses being tested. This paper describes the various study and analysis categories used for such analyses, including the advantages and limitations of such techniques...
The genetics of multiple sclerosis: an up-to-date reviewPierre Antoine Gourraud
Department of Neurology, University of California San Francisco, San Francisco, CA 94143 0435, USA
Immunol Rev 248:87-103. 2012....
Analytical methods for immunogenetic population dataSteven J Mack
Center for Genetics, Children s Hospital and Research Center Oakland, Oakland, CA, USA
Methods Mol Biol 882:215-44. 2012..The extent to which the data and analyses are appropriate to each other should be determined before any analyses are performed...
A genome-wide association study of brain lesion distribution in multiple sclerosisPierre Antoine Gourraud
Department of Neurology, School of Medicine, University of California, San Francisco, 675 Nelson Rising Lane, Suite 215, San Francisco, CA 94158, USA
Brain 136:1012-24. 2013....
Evaluating the genomic and sequence integrity of human ES cell lines; comparison to normal genomesWalter D Funk
BioTime, Inc, Alameda, CA, USA
Stem Cell Res 8:154-64. 2012..The combined application of cytogenetic and molecular technologies provides a detailed understanding of genomic and sequence profiles of GMP produced ES lines for potential use as therapeutic agents...
Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis datasetPouya Khankhanian
Department of Neurology, University of California, San Francisco, CA 94143 0435, USA
BMC Genomics 11:626. 2010..Attempts at replication of these genetic results in human studies, however, have reached conflicting conclusions...
Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosisEllen M Mowry
Multiple Sclerosis Center, Department of Neurology, University of California at San Francisco, San Francisco, CA, USA
Ann Neurol 72:234-40. 2012..We sought to determine whether vitamin D status is associated with developing new T2 lesions or contrast-enhancing lesions on brain magnetic resonance imaging (MRI) in relapsing multiple sclerosis (MS)...
A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32Wendy Cozen
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
Blood 119:469-75. 2012..In a separate analysis, the DRB1*0701 allele was associated with a decreased risk of NSHL (OR = 0.5, 95% confidence interval = 0.4, 0.7). These data support the importance of the HLA class II region in NSHL etiology...
B cell exchange across the blood-brain barrier in multiple sclerosisH Christian von Büdingen
Department of Neurology, UCSF, San Francisco, California 94158, USA
J Clin Invest 122:4533-43. 2012..These data also provide a powerful approach to identify and monitor B cells in the PB that correspond to clonally amplified populations in the CNS in MS and other inflammatory states...
An admission bioclinical score to predict 1-year outcomes in patients undergoing aneurysm coilingVincent Degos
Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94110, USA
Stroke 43:1253-9. 2012..Our goal was to develop, compare, and validate a predictive score for 1-year outcomes in patients with coiled subarachnoid hemorrhage...
A community standard for immunogenomic data reporting and analysis: proposal for a STrengthening the REporting of Immunogenomic Studies statementJ A Hollenbach
Center for Genetics, Children s Hospital and Research Center Oakland, Oakland, CA, USA
Tissue Antigens 78:333-44. 2011..As with the STREGA guidelines, the intent behind STREIS is not to dictate the design of immunogenomic studies, but to ensure consistent and transparent reporting of research, facilitating the synthesis of HLA and KIR data across studies...
