S S Gottlieb

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. doi request reprint The effects of adenosine A(1) receptor antagonism in patients with acute decompensated heart failure and worsening renal function: the REACH UP study
    Stephen S Gottlieb
    University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21209, USA
    J Card Fail 16:714-9. 2010
  2. doi request reprint Beta-blockers post-MI: an example of age discrimination?
    Stephen Gottlieb
    Department of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA
    Postgrad Med 112:28-33. 2002
  3. ncbi request reprint Adenosine A1 antagonists and the cardiorenal syndrome
    Stephen S Gottlieb
    University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Curr Heart Fail Rep 5:105-9. 2008
  4. doi request reprint Effects of BG9928, an adenosine A₁ receptor antagonist, in patients with congestive heart failure
    Stephen S Gottlieb
    University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    J Clin Pharmacol 51:899-907. 2011
  5. ncbi request reprint A double-blind placebo-controlled pilot study of controlled-release paroxetine on depression and quality of life in chronic heart failure
    Stephen S Gottlieb
    University of Maryland School of Medicine and the Baltimore VAMC, Baltimore, MD, USA
    Am Heart J 153:868-73. 2007
  6. pmc Relation of depression to severity of illness in heart failure (from Heart Failure And a Controlled Trial Investigating Outcomes of Exercise Training [HF-ACTION])
    Stephen S Gottlieb
    University of Maryland, Baltimore, Maryland, USA
    Am J Cardiol 103:1285-9. 2009
  7. ncbi request reprint Highlights of the 2006 scientific sessions of the Heart Failure Society of America: Seattle, Washington, September 10-13, 2006
    Stephen S Gottlieb
    University of Maryland, Baltimore, Maryland 21201, USA
    J Am Coll Cardiol 49:608-15. 2007
  8. ncbi request reprint The influence of age, gender, and race on the prevalence of depression in heart failure patients
    Stephen S Gottlieb
    Department of Medicine, University of Maryland School of Medicine, and Baltimore Veterans Administration Medical Center, 21201, USA
    J Am Coll Cardiol 43:1542-9. 2004
  9. ncbi request reprint Tolerability of beta-blocker initiation and titration in the Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF)
    Stephen S Gottlieb
    University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Circulation 105:1182-8. 2002
  10. ncbi request reprint Effects of BG9719 (CVT-124), an A1-adenosine receptor antagonist, and furosemide on glomerular filtration rate and natriuresis in patients with congestive heart failure
    S S Gottlieb
    Department of Medicine, University of Maryland School of Medicine, Baltimore 21201, USA
    J Am Coll Cardiol 35:56-9. 2000

Detail Information

Publications46

  1. doi request reprint The effects of adenosine A(1) receptor antagonism in patients with acute decompensated heart failure and worsening renal function: the REACH UP study
    Stephen S Gottlieb
    University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21209, USA
    J Card Fail 16:714-9. 2010
    ....
  2. doi request reprint Beta-blockers post-MI: an example of age discrimination?
    Stephen Gottlieb
    Department of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA
    Postgrad Med 112:28-33. 2002
    ..Underutilization of these drugs among the elderly is disconcerting given their benefit...
  3. ncbi request reprint Adenosine A1 antagonists and the cardiorenal syndrome
    Stephen S Gottlieb
    University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Curr Heart Fail Rep 5:105-9. 2008
    ..Ongoing studies should be able to demonstrate whether adenosine A1 antagonists can be used to improve renal function without adversely affecting patients with heart failure...
  4. doi request reprint Effects of BG9928, an adenosine A₁ receptor antagonist, in patients with congestive heart failure
    Stephen S Gottlieb
    University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    J Clin Pharmacol 51:899-907. 2011
    ..Single intravenous BG9928 doses of up to 1.0 mg/kg were well tolerated and increased sodium excretion without worsening renal function. Further studies are needed to determine the clinical benefit of adenosine A₁ receptor antagonism...
  5. ncbi request reprint A double-blind placebo-controlled pilot study of controlled-release paroxetine on depression and quality of life in chronic heart failure
    Stephen S Gottlieb
    University of Maryland School of Medicine and the Baltimore VAMC, Baltimore, MD, USA
    Am Heart J 153:868-73. 2007
    ....
  6. pmc Relation of depression to severity of illness in heart failure (from Heart Failure And a Controlled Trial Investigating Outcomes of Exercise Training [HF-ACTION])
    Stephen S Gottlieb
    University of Maryland, Baltimore, Maryland, USA
    Am J Cardiol 103:1285-9. 2009
    ..Addressing depression might improve symptoms in patients with HF...
  7. ncbi request reprint Highlights of the 2006 scientific sessions of the Heart Failure Society of America: Seattle, Washington, September 10-13, 2006
    Stephen S Gottlieb
    University of Maryland, Baltimore, Maryland 21201, USA
    J Am Coll Cardiol 49:608-15. 2007
  8. ncbi request reprint The influence of age, gender, and race on the prevalence of depression in heart failure patients
    Stephen S Gottlieb
    Department of Medicine, University of Maryland School of Medicine, and Baltimore Veterans Administration Medical Center, 21201, USA
    J Am Coll Cardiol 43:1542-9. 2004
    ..The goal of this study was to determine the prevalence of depression in an out-patient heart failure (HF) population; its relationship to quality of life (QOL); and the impact of gender, race, and age...
  9. ncbi request reprint Tolerability of beta-blocker initiation and titration in the Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF)
    Stephen S Gottlieb
    University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Circulation 105:1182-8. 2002
    ..beta-Blockade improves survival when administered over a long period of time to patients with heart failure. However, the time course of any possible deterioration during the titration phase has not been reported...
  10. ncbi request reprint Effects of BG9719 (CVT-124), an A1-adenosine receptor antagonist, and furosemide on glomerular filtration rate and natriuresis in patients with congestive heart failure
    S S Gottlieb
    Department of Medicine, University of Maryland School of Medicine, Baltimore 21201, USA
    J Am Coll Cardiol 35:56-9. 2000
    ..To determine the effects of furosemide and the selective A1 adenosine receptor BG9719 on renal function in patients with congestive heart failure (CHF)...
  11. ncbi request reprint BG9719 (CVT-124), an A1 adenosine receptor antagonist, protects against the decline in renal function observed with diuretic therapy
    Stephen S Gottlieb
    University of Maryland School of Medicine and the D V A Medical Center, Baltimore, MD, USA
    Circulation 105:1348-53. 2002
    ..Adenosine may adversely affect renal function via its effects on renal arterioles and tubuloglomerular feedback, but effects of adenosine blockade in humans receiving furosemide and ACE inhibitors is unknown...
  12. ncbi request reprint Are all beta-blockers the same for chronic heart failure?
    S S Gottlieb
    Division of Cardiology, University of Maryland Medical Systems, 22 South Greene Street, Baltimore, MD 21201, USA
    Curr Cardiol Rep 3:124-9. 2001
    ..The beta-blockers differ regarding beta-selectivity, vasodilation properties, and perhaps other ancillary properties. At present, the importance and consequences of these differences are unknown...
  13. ncbi request reprint Nesiritide does not improve renal function in patients with chronic heart failure and worsening serum creatinine
    David J Wang
    Department of Medicine, University of Maryland School of Medicine, and Baltimore Veterans Administration Medical Center, USA
    Circulation 110:1620-5. 2004
    ..However, studies of brain natriuretic peptide in patients with heart failure have come to conflicting conclusions about effects on glomerular filtration rate (GFR), effective renal plasma flow, natriuresis, and diuresis...
  14. ncbi request reprint Effect of chronic changes in heart rate on congestive heart failure
    Krishnamurti Rao
    The University of Maryland School of Medicine and the Baltimore Veteran s Affairs Medical Center, Baltimore, Maryland, USA
    J Card Fail 13:269-74. 2007
    ..We therefore sought to evaluate the impact of different heart rates on ejection fraction, 6-minute walk, and peak oxygen consumption (VO2) in heart failure patients...
  15. doi request reprint A randomized, controlled trial of the renal effects of ultrafiltration as compared to furosemide in patients with acute decompensated heart failure
    Hobart L Rogers
    University of Maryland School of Pharmacy, Baltimore, Maryland, USA
    J Card Fail 14:1-5. 2008
    ....
  16. pmc New York Heart Association functional class predicts exercise parameters in the current era
    Stuart D Russell
    Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Am Heart J 158:S24-30. 2009
    ..Using baseline data from the HF-ACTION (Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing) study, we examined this relationship...
  17. ncbi request reprint Acute congestive heart failure in the emergency department
    Robert L Rogers
    Division of Emergency Medicine, Department of Medicine, University of Maryland School of Medicine, 110 South Paca Street, Sixth Floor, Suite 200, Baltimore, MD 21201, USA
    Cardiol Clin 24:115-23, vii. 2006
    ..The approach to the critically ill patient who has heart failure should be multidisciplinary and involve the emergency physician and the cardiologist who will care for the patient...
  18. ncbi request reprint Effect of kidney transplantation on left ventricular systolic dysfunction and congestive heart failure in patients with end-stage renal disease
    Ravinder K Wali
    Division of Nephrology, Department of Medicine, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    J Am Coll Cardiol 45:1051-60. 2005
    ..We examined the impact of kidney transplantation on left ventricular ejection fraction (LVEF) in end-stage renal disease (ESRD) patients with congestive heart failure (CHF)...
  19. pmc Association between depressive symptoms and fibrosis markers: the Cardiovascular Health Study
    Willem J Kop
    Department of Medicine, University of Maryland, Baltimore, MD 21201, United States
    Brain Behav Immun 24:229-35. 2010
    ..Depression is associated with an increased risk of heart failure and other age-related diseases. This study examined the association between depressive symptoms and fibrosis markers in adults aged 65 years and above...
  20. doi request reprint Test-retest reliability of assessment for intraventricular dyssynchrony by tissue Doppler imaging echocardiography
    Mark R Vesely
    Division of Cardiology, Department of Medicine, University of Maryland Hospital and School of Medicine, Baltimore, MD, USA
    Am J Cardiol 101:645-50. 2008
    ..35). Bland-Altman analysis demonstrated wide confidence intervals, exceeding the diagnostic cutoff values for the respective criteria. In conclusion, the accurate assessment of IVD by TDI may be limited by poor test-retest reliability...
  21. doi request reprint Exploration of patients' readiness for an eHealth management program for chronic heart failure: a preliminary study
    Eun Shim Nahm
    University of Maryland School of Nursing, Baltimore, MD 21201, USA
    J Cardiovasc Nurs 23:463-71. 2008
    ..The findings showed the participants' high readiness to use the proposed eHealth program if access and training were provided. This study used a small convenience sample. Further studies are needed with larger, diverse samples...
  22. ncbi request reprint Renal effects of adenosine A1-receptor antagonists in congestive heart failure
    S S Gottlieb
    Division of Cardiology, University of Maryland School of Medicine, Baltimore 21201, USA
    Drugs 61:1387-93. 2001
    ..CVT-124 increased sodium excretion without decreasing glomerular filtration rate. These data suggest that adenosine might be an important determinant of renal function in patients with heart failure...
  23. ncbi request reprint Comparative effects of three beta blockers (atenolol, metoprolol, and propranolol) on survival after acute myocardial infarction
    S S Gottlieb
    Department of Medicine and Epidemiology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 87:823-6. 2001
    ..Although the use of beta blockade after AMI has major prognostic importance, the present study suggests that the specific beta blocker chosen will have little influence on mortality...
  24. ncbi request reprint Effect of metoprolol on absolute myocardial blood flow in patients with heart failure secondary to ischemic or nonischemic cardiomyopathy
    Susan K Bennett
    Division of Nuclear Medicine and Cardiology, The University of Maryland Medical Center and School of Medicine, Baltimore, Maryland 21201 1595, USA
    Am J Cardiol 89:1431-4. 2002
  25. ncbi request reprint Current concepts for the neurohormonal management of left ventricular dysfunction after myocardial infarction
    Keyur B Shah
    University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Curr Heart Fail Rep 1:161-7. 2004
    ..In particular, the roles of endothelin, matrix metalloproteinases, and cytokines in remodeling are being investigated, with the potential to result in better outcomes for patients...
  26. ncbi request reprint Quality of life and psychological status of patients with implantable cardioverter defibrillators
    E Friedmann
    University of Maryland School of Nursing, 655 W Lombard Street, Baltimore, MD 21201 1579, USA
    J Interv Card Electrophysiol 17:65-72. 2006
    ....
  27. ncbi request reprint Relationship of depression, anxiety, and social isolation to chronic heart failure outpatient mortality
    Erika Friedmann
    School of Nursing, University of Maryland, Baltimore, MD 21201, USA
    Am Heart J 152:940.e1-8. 2006
    ..The Psychosocial Factors Outcome Study (PFOS) investigated the prevalence of depression and anxiety and the relationship of psychosocial factors to mortality in outpatients with heart failure (HF)...
  28. ncbi request reprint The adequacy of laboratory monitoring in patients treated with spironolactone for congestive heart failure
    Keyur B Shah
    Department of Medicine, The University of Maryland School of Medicine and the Baltimore Veterans Affairs Medical Center, Baltimore, Maryland, USA
    J Am Coll Cardiol 46:845-9. 2005
    ..This study was designed to determine the adequacy of monitoring patients receiving spironolactone as well as spironolactone's relationship to hyperkalemia...
  29. ncbi request reprint Exercise in the geriatric patient with congestive heart failure
    S S Gottlieb
    Department of Medicine, Division of Cardiology, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Am J Geriatr Cardiol 10:264-8. 2001
    ..However, they are less likely to tolerate an exercise program and may not improve their quality of life if the exercise is excessive. Caution is warranted when exercise is prescribed to elderly patients with heart failure...
  30. ncbi request reprint The prognostic importance of different definitions of worsening renal function in congestive heart failure
    Stephen S Gottlieb
    Division of Cardiology, University of Maryland School of Medicine and the D V A Medical Center, Baltimore, Maryland 21201, USA
    J Card Fail 8:136-41. 2002
    ..We therefore compared the prognostic importance of various definitions of worsening renal function in 1,002 patients hospitalized for congestive heart failure (CHF)...
  31. doi request reprint Changes in psychosocial distress in outpatients with heart failure with implantable cardioverter defibrillators
    Sue A Thomas
    University of Maryland, School of Nursing, Baltimore, Maryland 21201 1579, USA
    Heart Lung 38:109-20. 2009
    ..A significant proportion of ICD recipients were depressed or anxious, or had diminished social support even after 2 years. Investigation of strategies to improve ICD recipients' psychosocial status is warranted...
  32. ncbi request reprint Sex, digitalis, and the sodium pump
    Mordecai P Blaustein
    Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Mol Interv 3:68-72, 50. 2003
    ..Blaustein and colleagues delve into the report and discuss possible explanations for these findings, suggest alternative ones, and advocate for enrolling greater numbers of women in clinical studies...
  33. ncbi request reprint Robust gene expression with amplified RNA from biopsy-sized human heart tissue
    Brian R Barrows
    Department of Physiology, University of Maryland Baltimore, Baltimore, MD 21201, USA
    J Mol Cell Cardiol 42:260-4. 2007
    ..Ability to measure gene expression from nanogram amounts of RNA will provide new opportunities to predict progression to symptomatic heart failure, and to identify potential targets for therapy...
  34. ncbi request reprint The characteristics and prognostic importance of NT-ProBNP concentrations in critically ill patients
    Keyur B Shah
    University of Maryland School of Medicine, Baltimore, USA
    Am J Med 120:1071-7. 2007
    ..We evaluate amino-terminal brain natriuretic peptide (NT-proBNP) in the medical ICU, specifically its correlation with noncardiac admission diagnosis and prognosis of critically ill patients...
  35. ncbi request reprint B-type natriuretic peptide and N-terminal pro B-type natriuretic peptide are depressed in obesity despite higher left ventricular end diastolic pressures
    Jennifer A Taylor
    The University of Maryland School of Medicine and the Baltimore Veteran s Affairs Medical Center, Baltimore, MD, USA
    Am Heart J 152:1071-6. 2006
    ..The relationship between these markers and left ventricular end diastolic pressure (LVEDP) in obesity has not been elucidated...
  36. doi request reprint Diuretics: still the mainstay of treatment
    David J Wang
    Department of Medicine, University of Maryland School of Medicine, and Baltimore Veterans Administration Medical Center, Baltimore, MD, USA
    Crit Care Med 36:S89-94. 2008
    ..Diuretics improve symptoms but should be used in addition to other agents that improve the long-term outcome of patients with heart failure...
  37. ncbi request reprint Impedance cardiography: more questions than answers
    David J Wang
    Division of Cardiology, University of Maryland School of Medicine, MD 21201, USA
    Curr Cardiol Rep 8:180-6. 2006
    ..There are limited data demonstrating any improved outcomes using ICG in the clinical setting. Given the available data, ICG use should be limited to the research setting...
  38. ncbi request reprint Metoprolol reverses left ventricular remodeling in patients with asymptomatic systolic dysfunction: the REversal of VEntricular Remodeling with Toprol-XL (REVERT) trial
    Wilson S Colucci
    Cardiovascular Medicine, Boston University Medical Center, 88 E Newton St, Boston, MA 02118, USA
    Circulation 116:49-56. 2007
    ..We investigated whether beta-blocker therapy ameliorates left ventricular remodeling in asymptomatic patients with left ventricular systolic dysfunction...
  39. ncbi request reprint Metoprolol CR/XL in female patients with heart failure: analysis of the experience in Metoprolol Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF)
    Jalal K Ghali
    Cardiac Centers of Louisiana, Shreveport, LA 71103, USA
    Circulation 105:1585-91. 2002
    ..Underrepresentation of women in heart failure clinical trials has limited conclusions regarding the effect of various management strategies on survival in women with heart failure and decreased left ventricular ejection fraction (LVEF)...
  40. ncbi request reprint Consistency of the beneficial effect of metoprolol succinate extended release across a wide range dose of angiotensin-converting enzyme inhibitors and digitalis
    Jalal K Ghali
    Cardiac Centers of Louisiana, 2551 Greenwood Road, Suite 350, Shreveport, LA 71103, USA
    J Card Fail 10:452-9. 2004
    ....
  41. ncbi request reprint Relationship between heart failure treatment and development of worsening renal function among hospitalized patients
    Javed Butler
    Vanderbilt University, Nashville, Tenn, USA
    Am Heart J 147:331-8. 2004
    ..Whether treatment for HF contributes to WRF is unknown. In this study, we sought to assess whether acute treatment for patients who were hospitalized with HF contributes to WRF...
  42. ncbi request reprint Cardiac resynchronization therapy for heart failure
    Stephen S Gottlieb
    N Engl J Med 347:1803-4; author reply 1803-4. 2002
  43. ncbi request reprint Incidence, predictors at admission, and impact of worsening renal function among patients hospitalized with heart failure
    Daniel E Forman
    Section of Cardiology, Boston Medical Center, Boston, Massachusetts 02188, USA
    J Am Coll Cardiol 43:61-7. 2004
    ..The goal of this study was to determine the prevalence of worsening renal function (WRF) among hospitalized heart failure (HF) patients, clinical predictors of WRF, and hospital outcomes associated with WRF...
  44. ncbi request reprint Vasopressin v(2) receptor blockade with tolvaptan versus fluid restriction in the treatment of hyponatremia
    Mihai Gheorghiade
    Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA
    Am J Cardiol 97:1064-7. 2006
    ..No differences in adverse events were observed between the groups. In conclusion, tolvaptan appears to be more effective than fluid restriction at correcting hyponatremia in hospitalized subjects, without an increase in adverse events...
  45. ncbi request reprint Perioperative beta-blockade: a survey of physician attitudes in the department of Veterans Affairs
    Martin J London
    Department of Anesthesia and Perioperative Care, San Francisco Veterans Affairs Medical Center, University of California, San Francisco, CA, USA
    J Cardiothorac Vasc Anesth 18:14-24. 2004
    ..To delineate clinician opinion on the efficacy, safety, and logistics of perioperative beta-adrenergic blockade for patients undergoing noncardiac surgery...
  46. ncbi request reprint Implantable cardioverter-defibrillator therapy after myocardial infarction
    Keyur B Shah
    N Engl J Med 352:1039-41; author reply 1039-41. 2005