JEFFREY GORSKI

Summary

Affiliation: University of Missouri-Kansas City
Country: USA

Publications

  1. ncbi request reprint New alternatively spliced form of galectin-3, a member of the beta-galactoside-binding animal lectin family, contains a predicted transmembrane-spanning domain and a leucine zipper motif
    Jeff P Gorski
    Division of Molecular Biology and Biochemistry, School of Biological Sciences, and Department of Oral Biology, Dental School, University of Missouri Kansas City, Kansas City, Missouri 64110, USA
    J Biol Chem 277:18840-8. 2002
  2. ncbi request reprint Biomineralization of bone: a fresh view of the roles of non-collagenous proteins
    JEFFREY PAUL GORSKI
    Center of Excellence in the Study of Musculoskeletal and Dental Tissues and Dept of Oral Biology, Sch Of Dentistry, Univ of Missouri Kansas City, Kansas City, MO 64108, USA
    Front Biosci (Landmark Ed) 16:2598-621. 2011
  3. ncbi request reprint Hypercalcemia during the osteogenic phase after rat marrow ablation coincides with increased bone resorption assessed by the NTx marker
    J P Gorski
    Division of Molecular Biology and Biochemistry, School of Biological Sciences, University of Missouri Kansas City, Kansas City, MO 64110, USA
    Bone 27:103-10. 2000
  4. pmc Potential role of proprotein convertase SKI-1 in the mineralization of primary bone
    Jeff P Gorski
    Department of Oral Biology, School of Dentistry, University of Missouri at Kansas City, Kansas City, MO 64108, USA
    Cells Tissues Organs 189:25-32. 2009
  5. pmc Eliminating exposure to aqueous solvents is necessary for the early detection and ultrastructural elemental analysis of sites of calcium and phosphorus enrichment in mineralizing UMR106-01 osteoblastic cultures
    Daniel Studer
    Institute of Anatomy, University of Bern, Bern, Switzerland
    Cells Tissues Organs 194:138-45. 2011
  6. ncbi request reprint Extracellular bone acidic glycoprotein-75 defines condensed mesenchyme regions to be mineralized and localizes with bone sialoprotein during intramembranous bone formation
    Jeff P Gorski
    Division of Biochemistry and Molecular Biology, School of Biological Sciences, School of Dentistry, University of Missouri Kansas City, Kansas City, Missouri 64108, USA
    J Biol Chem 279:25455-63. 2004
  7. pmc Inhibition of proprotein convertase SKI-1 blocks transcription of key extracellular matrix genes regulating osteoblastic mineralization
    Jeff P Gorski
    Center of Excellence in the Study of Musculoskeletal and Dental Tissues and Department of Oral Biology, School of Dentistry, University of Missouri Kansas City, Kansas City, Missouri 64108, USA
    J Biol Chem 286:1836-49. 2011
  8. pmc Association of specific proteolytic processing of bone sialoprotein and bone acidic glycoprotein-75 with mineralization within biomineralization foci
    Nichole T Huffman
    Bone Biology Program, Department of Oral Biology, School of Dentistry, University of Missouri, Kansas City, Missouri 64108, USA
    J Biol Chem 282:26002-13. 2007
  9. pmc Confocal laser Raman microspectroscopy of biomineralization foci in UMR 106 osteoblastic cultures reveals temporally synchronized protein changes preceding and accompanying mineral crystal deposition
    Chuanyi Wang
    Biomaterials Section, Department of Oral Biology, School of Dentistry, University of Missouri, Kansas City, Missouri 64108, USA
    J Biol Chem 284:7100-13. 2009

Research Grants

  1. MINERALIZATION OF PRIMARY BONE
    JEFFREY GORSKI; Fiscal Year: 2007
  2. BAG-75: UNIQUE MARKER OF PRIMARY BONE FORMATION
    JEFFREY GORSKI; Fiscal Year: 2003
  3. MINERALIZATION OF PRIMARY BONE
    JEFFREY GORSKI; Fiscal Year: 2005
  4. MINERALIZATION OF PRIMARY BONE
    JEFFREY GORSKI; Fiscal Year: 2006

Collaborators

Detail Information

Publications9

  1. ncbi request reprint New alternatively spliced form of galectin-3, a member of the beta-galactoside-binding animal lectin family, contains a predicted transmembrane-spanning domain and a leucine zipper motif
    Jeff P Gorski
    Division of Molecular Biology and Biochemistry, School of Biological Sciences, and Department of Oral Biology, Dental School, University of Missouri Kansas City, Kansas City, Missouri 64110, USA
    J Biol Chem 277:18840-8. 2002
    ..Gal-3TM1 is the first example of a galectin superfamily member capable of being expressed as a soluble protein and as a transmembrane protein...
  2. ncbi request reprint Biomineralization of bone: a fresh view of the roles of non-collagenous proteins
    JEFFREY PAUL GORSKI
    Center of Excellence in the Study of Musculoskeletal and Dental Tissues and Dept of Oral Biology, Sch Of Dentistry, Univ of Missouri Kansas City, Kansas City, MO 64108, USA
    Front Biosci (Landmark Ed) 16:2598-621. 2011
    ....
  3. ncbi request reprint Hypercalcemia during the osteogenic phase after rat marrow ablation coincides with increased bone resorption assessed by the NTx marker
    J P Gorski
    Division of Molecular Biology and Biochemistry, School of Biological Sciences, University of Missouri Kansas City, Kansas City, MO 64110, USA
    Bone 27:103-10. 2000
    ....
  4. pmc Potential role of proprotein convertase SKI-1 in the mineralization of primary bone
    Jeff P Gorski
    Department of Oral Biology, School of Dentistry, University of Missouri at Kansas City, Kansas City, MO 64108, USA
    Cells Tissues Organs 189:25-32. 2009
    ....
  5. pmc Eliminating exposure to aqueous solvents is necessary for the early detection and ultrastructural elemental analysis of sites of calcium and phosphorus enrichment in mineralizing UMR106-01 osteoblastic cultures
    Daniel Studer
    Institute of Anatomy, University of Bern, Bern, Switzerland
    Cells Tissues Organs 194:138-45. 2011
    ....
  6. ncbi request reprint Extracellular bone acidic glycoprotein-75 defines condensed mesenchyme regions to be mineralized and localizes with bone sialoprotein during intramembranous bone formation
    Jeff P Gorski
    Division of Biochemistry and Molecular Biology, School of Biological Sciences, School of Dentistry, University of Missouri Kansas City, Kansas City, Missouri 64108, USA
    J Biol Chem 279:25455-63. 2004
    ....
  7. pmc Inhibition of proprotein convertase SKI-1 blocks transcription of key extracellular matrix genes regulating osteoblastic mineralization
    Jeff P Gorski
    Center of Excellence in the Study of Musculoskeletal and Dental Tissues and Department of Oral Biology, School of Dentistry, University of Missouri Kansas City, Kansas City, Missouri 64108, USA
    J Biol Chem 286:1836-49. 2011
    ..Our results indicate that the differentiated phenotype of osteoblastic cells and possibly osteocytes depends upon the non-apoptotic actions of SKI-1...
  8. pmc Association of specific proteolytic processing of bone sialoprotein and bone acidic glycoprotein-75 with mineralization within biomineralization foci
    Nichole T Huffman
    Bone Biology Program, Department of Oral Biology, School of Dentistry, University of Missouri, Kansas City, Missouri 64108, USA
    J Biol Chem 282:26002-13. 2007
    ....
  9. pmc Confocal laser Raman microspectroscopy of biomineralization foci in UMR 106 osteoblastic cultures reveals temporally synchronized protein changes preceding and accompanying mineral crystal deposition
    Chuanyi Wang
    Biomaterials Section, Department of Oral Biology, School of Dentistry, University of Missouri, Kansas City, Missouri 64108, USA
    J Biol Chem 284:7100-13. 2009
    ..Finally, the low extent of spectral variability detected among different BMF at the same time point indicates that mineralization of individual BMF within a culture is synchronized...

Research Grants5

  1. MINERALIZATION OF PRIMARY BONE
    JEFFREY GORSKI; Fiscal Year: 2007
    ..Results of this work should better define the differences between primariy and lamellar bone, as well as aid in the diagnosis and treatment of osteoporosis and atherosclerosis. ..
  2. BAG-75: UNIQUE MARKER OF PRIMARY BONE FORMATION
    JEFFREY GORSKI; Fiscal Year: 2003
    ..Stimulation of appositional formation by lamellar bone would not be expected to have the same effect. These future functional studies require determination of the BAG-75 cDNA sequence. ..
  3. MINERALIZATION OF PRIMARY BONE
    JEFFREY GORSKI; Fiscal Year: 2005
    ..Results of this work should better define the differences between primariy and lamellar bone, as well as aid in the diagnosis and treatment of osteoporosis and atherosclerosis. ..
  4. MINERALIZATION OF PRIMARY BONE
    JEFFREY GORSKI; Fiscal Year: 2006
    ..Results of this work should better define the differences between primariy and lamellar bone, as well as aid in the diagnosis and treatment of osteoporosis and atherosclerosis. ..