L K Gordon

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Orbital inflammatory disease: a diagnostic and therapeutic challenge
    L K Gordon
    Jules Stein Eye Institute, University of California at Los Angeles and Greater Los Angeles Veterans Affairs Healthcare System, Los Angeles, CA, USA
    Eye (Lond) 20:1196-206. 2006
  2. pmc Peripheral myelin protein-22 (PMP22) modulates alpha 6 integrin expression in the human endometrium
    Rajiv G Rao
    Department of Pathology and Laboratory Medicine, University of California, Los Angeles, USA
    Reprod Biol Endocrinol 9:56. 2011
  3. pmc Steroid hormone regulation of EMP2 expression and localization in the endometrium
    Madhuri Wadehra
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Reprod Biol Endocrinol 6:15. 2008
  4. ncbi request reprint Longitudinal cohort study of patients with birdshot chorioretinopathy. IV. Visual field results at baseline
    Lynn K Gordon
    Ocular Inflammatory Disease Center, Jules Stein Eye Institute and the Department of Ophthalmology, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, CA 90095, USA
    Am J Ophthalmol 144:829-837. 2007
  5. ncbi request reprint Standardized visual field assessment for patients with birdshot chorioretinopathy
    Lynn K Gordon
    Ophthalmology Section, Greater Los Angeles VA Healthcare System, Los Angeles, CA 90095, USA
    Ocul Immunol Inflamm 14:325-32. 2006
  6. ncbi request reprint Diagnostic dilemmas in orbital inflammatory disease
    Lynn K Gordon
    Jules Stein Eye Institute, University of California Los Angeles and Greater Los Angeles VA Healthcare System, Los Angeles, CA, USA
    Ocul Immunol Inflamm 11:3-15. 2003
  7. ncbi request reprint Epithelial membrane protein-2 is expressed in discrete anatomical regions of the eye
    Madhuri Wadehra
    Department of Pathology and Laboratory Medicine, Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095, USA
    Exp Mol Pathol 74:106-12. 2003
  8. ncbi request reprint The tetraspan protein EMP2 regulates expression of caveolin-1
    Ashley Forbes
    Molecular Biology Institute, David Geffen School of Medicine, UCLA, Los Angeles, California 90095, USA
    J Biol Chem 282:26542-51. 2007
  9. ncbi request reprint Surveillance of the eye and vision in clinical trials of CP-675,206 for metastatic melanoma
    Bradley R Straatsma
    Department of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, Los Angeles, California 90095, USA
    Am J Ophthalmol 143:958-969. 2007
  10. ncbi request reprint BetaB1-crystallin: identification of a candidate ciliary body uveitis antigen
    David Stempel
    Department of Ophthalmology, University of California Los Angeles, Jules Stein Eye Institute, 100 Stein Plaza, Los Angeles, CA 90095, USA
    Invest Ophthalmol Vis Sci 44:203-9. 2003

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Orbital inflammatory disease: a diagnostic and therapeutic challenge
    L K Gordon
    Jules Stein Eye Institute, University of California at Los Angeles and Greater Los Angeles Veterans Affairs Healthcare System, Los Angeles, CA, USA
    Eye (Lond) 20:1196-206. 2006
    ....
  2. pmc Peripheral myelin protein-22 (PMP22) modulates alpha 6 integrin expression in the human endometrium
    Rajiv G Rao
    Department of Pathology and Laboratory Medicine, University of California, Los Angeles, USA
    Reprod Biol Endocrinol 9:56. 2011
    ..In this study, we first characterized the expression of PMP22 in the human menstrual cycle and began to characterize its function in the endometrium...
  3. pmc Steroid hormone regulation of EMP2 expression and localization in the endometrium
    Madhuri Wadehra
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Reprod Biol Endocrinol 6:15. 2008
    ..Because EMP2 is differentially expressed in the various stages of the murine and human estrous cycle, we tested the hypothesis that the steroid hormones progesterone and estrogen influence EMP2 expression and localization...
  4. ncbi request reprint Longitudinal cohort study of patients with birdshot chorioretinopathy. IV. Visual field results at baseline
    Lynn K Gordon
    Ocular Inflammatory Disease Center, Jules Stein Eye Institute and the Department of Ophthalmology, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, CA 90095, USA
    Am J Ophthalmol 144:829-837. 2007
    ....
  5. ncbi request reprint Standardized visual field assessment for patients with birdshot chorioretinopathy
    Lynn K Gordon
    Ophthalmology Section, Greater Los Angeles VA Healthcare System, Los Angeles, CA 90095, USA
    Ocul Immunol Inflamm 14:325-32. 2006
    ..To adapt a standardized technique for assessment of visual fields to the study of patients with birdshot chorioretinopathy and to describe visual field patterns and changes over time for affected individuals...
  6. ncbi request reprint Diagnostic dilemmas in orbital inflammatory disease
    Lynn K Gordon
    Jules Stein Eye Institute, University of California Los Angeles and Greater Los Angeles VA Healthcare System, Los Angeles, CA, USA
    Ocul Immunol Inflamm 11:3-15. 2003
    ..The purpose of this review is to provide an overview of the spectrum of diseases known as OID, with emphasis on specific diagnostic challenges in the evaluation and management of patients with idiopathic OID...
  7. ncbi request reprint Epithelial membrane protein-2 is expressed in discrete anatomical regions of the eye
    Madhuri Wadehra
    Department of Pathology and Laboratory Medicine, Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095, USA
    Exp Mol Pathol 74:106-12. 2003
    ..This distribution is distinct from other TM4SF proteins and may relate to a role in apical membrane recycling...
  8. ncbi request reprint The tetraspan protein EMP2 regulates expression of caveolin-1
    Ashley Forbes
    Molecular Biology Institute, David Geffen School of Medicine, UCLA, Los Angeles, California 90095, USA
    J Biol Chem 282:26542-51. 2007
    ..These findings elucidate a new mechanism of caveolin-1 regulation and define an additional role for EMP2 as a key regulator of cell membrane composition...
  9. ncbi request reprint Surveillance of the eye and vision in clinical trials of CP-675,206 for metastatic melanoma
    Bradley R Straatsma
    Department of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, Los Angeles, California 90095, USA
    Am J Ophthalmol 143:958-969. 2007
    ..To determine the ocular safety of CP-675,206 (Pfizer, New York, New York, USA), a fully human anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody in clinical trials of immunotherapy of metastatic melanoma...
  10. ncbi request reprint BetaB1-crystallin: identification of a candidate ciliary body uveitis antigen
    David Stempel
    Department of Ophthalmology, University of California Los Angeles, Jules Stein Eye Institute, 100 Stein Plaza, Los Angeles, CA 90095, USA
    Invest Ophthalmol Vis Sci 44:203-9. 2003
    ..In this study, a recombinantly isolated pANCA monoclonal antibody was used to identify the corresponding antigenic target(s) in the ciliary body...
  11. doi request reprint A comparison of semiautomated versus manual Goldmann kinetic perimetry in patients with visually significant glaucoma
    Adriana M Ramirez
    David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    J Glaucoma 17:111-7. 2008
    ..To determine if semiautomated kinetic perimetry (SKP) is reproducible and comparable to Goldmann manual kinetic perimetry (GVF)...
  12. ncbi request reprint Co-expression of heat shock transcription factors 1 and 2 in rat retinal ganglion cells
    Jacky M K Kwong
    Department of Ophthalmology, University of California Los Angeles, Los Angeles, CA 90095 7000, USA
    Neurosci Lett 405:191-5. 2006
    ..Our findings suggest that both heat shock transcription factors 1 and 2 are linked to the heat shock response in retinal ganglion cells...
  13. ncbi request reprint Longitudinal cohort study of patients with birdshot chorioretinopathy. I. Baseline clinical characteristics
    Dominique Monnet
    Service d Ophtalmologie, Hôpital Cochin and Université Paris 5, 27 rue du Faubourg Saint Jacques, 75679 Paris Cedex 14, France
    Am J Ophthalmol 141:135-42. 2006
    ..To describe baseline clinical characteristics of a cohort of 80 patients with birdshot chorioretinopathy in anticipation of a longitudinal study, and to identify relationships between visual acuity, symptoms, and ophthalmic findings...
  14. ncbi request reprint Birdshot chorioretinopathy
    Kayur H Shah
    Ocular Inflammatory Disease Center, Jules Stein Eye Institute, and the Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 7000, USA
    Surv Ophthalmol 50:519-41. 2005
    ..Further study is needed to determine the optimal methods for treating and monitoring patients with birdshot chorioretinopathy...
  15. ncbi request reprint Epithelial membrane protein-2 regulates surface expression of alphavbeta3 integrin in the endometrium
    Madhuri Wadehra
    Department of Pathology and Laboratory, University of California, Los Angeles, CA 90095, USA
    Dev Biol 287:336-45. 2005
    ....
  16. ncbi request reprint Surveillance of the eye and vision in a clinical trial of MART1-transformed dendritic cells for metastatic melanoma
    Lynn K Gordon
    Department of Ophthalmology, and the Jules Stein Eye Institute, and the UCLA Jonsson Comprehensive Cancer Center, University of California at Los Angeles, 100 Stein Plaza, Los Angeles, CA 90095 7000, USA
    Control Clin Trials 25:400-7. 2004
    ..To report the protocol for surveillance of the eye and vision in a clinical trial of MART1-transduced dendritic cells for metastatic melanoma...
  17. doi request reprint Tubulointerstitial nephritis and uveitis syndrome: a case with an autoimmune reactivity against retinal and renal antigens
    Kaori Shimazaki
    Molecular Biology Institute, University of California, David Geffen School of Medicine, Los Angeles, California 90095, USA
    Ocul Immunol Inflamm 16:51-3. 2008
    ..A previous report detected a renal antigen recognized by the serum of a TINU patient. In this report the authors extend these observations to document seroreactivity against a retinal antigen of similar size...
  18. pmc The need for standardization of antiretinal antibody detection and measurement
    Farzin Forooghian
    Division of Epidemiology and Clinical Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Ophthalmol 146:489-95. 2008
    ..To review the current literature on the detection and measurement of antiretinal antibodies...
  19. doi request reprint Frequency of anti-retinal antibodies in normal human serum
    Kaori Shimazaki
    Molecular Biology Institute, University of California, Los Angeles David Geffen School of Medicine, Los Angeles, California, USA
    J Neuroophthalmol 28:5-11. 2008
    ..The purpose of this work was to identify the profile of anti-retinal IgG antibodies in serum used as controls in laboratory testing...
  20. ncbi request reprint Identification of candidate microbial sequences from inflammatory lesion of giant cell arteritis
    Lynn K Gordon
    Jules Stein Eye Institute, UCLA School of Medicine and the Greater Los Angeles Veterans Affairs Healthcare System, Los Angeles, CA 90095 1732, USA
    Clin Immunol 111:286-96. 2004
    ..An examination of serum from GCA(+) individuals (in contrast to healthy age-matched controls) showed the presence of IgG which recognized in vitro translated proteins from these clones...
  21. ncbi request reprint Etanercept associated optic neuropathy
    Vicky Chang
    Clin Experiment Ophthalmol 35:680-2. 2007
    ..Such cases demonstrate the importance of prompt ophthalmologic evaluation of visual changes in patients being treated with anti-TNF-alpha antagonists...
  22. ncbi request reprint Epithelial membrane protein 2 modulates infectivity of Chlamydia muridarum (MoPn)
    Kaori Shimazaki
    Molecular Biology Institute, Los Angeles, CA 90095, USA
    Microbes Infect 9:1003-10. 2007
    ..These findings identify EMP2 as a candidate host protein involved in infection of C. muridarum (MoPn)...
  23. ncbi request reprint The tetraspan protein EMP2 increases surface expression of class I major histocompatibility complex proteins and susceptibility to CTL-mediated cell death
    Madhuri Wadehra
    Department of Pathology and Laboratory Medicine, University of California at Los Angeles, Los Angeles, CA 90095 1722, USA
    Clin Immunol 107:129-36. 2003
    ..This study demonstrates an unexpected role for a tetraspan protein in CTL-mediated cell death and MHC1 surface trafficking...
  24. ncbi request reprint Uveitis seroreactivity to candidate pANCA antigens: mycobacterial HupB and histone H1(69-171)
    Hallie Kassan
    Jules Stein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Ocul Immunol Inflamm 13:191-8. 2005
    ..Histone H1 (H1) and mycobacterial HupB (HupB) are recently identified candidate pANCA antigens. This study addresses the hypothesis that H1 and HupB are targets of disease-associated seroreactivity in pANCA+ uveitis...
  25. ncbi request reprint Retinal ganglion cell disorders: types and treatments
    Leonard A Levin
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA
    Prog Retin Eye Res 21:465-84. 2002

Research Grants2

  1. Beta-B1 Crystallin - a New Candidate Uveitis Autoantigen
    Lynn Gordon; Fiscal Year: 2003
    ..abstract_text> ..
  2. Novel Therapies to Prevent Blindness Caused by Proliferative Vitreoretinopathy
    David G Telander; Fiscal Year: 2010
    ..The relevance to public health would be to use the observations that result from this study and develop a new therapy that will either prevent or effectively treat PVR. ..