Albert M Gordon

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Cooperative activation of skeletal and cardiac muscle
    A M Gordon
    Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, USA
    Adv Exp Med Biol 538:371-8; discussion 378-9. 2003
  2. pmc Calcium regulation of skeletal muscle thin filament motility in vitro
    A M Gordon
    Department of Physiology and Biophysics, University of Washington, Seattle 98195, USA
    Biophys J 72:1295-307. 1997
  3. ncbi request reprint Regulation of contraction in striated muscle
    A M Gordon
    Department of Physiology and Biophysics, University of Washington, Seattle, Washington 98195 7290, USA
    Physiol Rev 80:853-924. 2000
  4. pmc Ca2+ regulation of rabbit skeletal muscle thin filament sliding: role of cross-bridge number
    Bo Liang
    Department of Physiology and Biophysics, University of Washington, Seattle, Washington 98195, USA
    Biophys J 85:1775-86. 2003
  5. pmc Thin filament near-neighbour regulatory unit interactions affect rabbit skeletal muscle steady-state force-Ca(2+) relations
    Michael Regnier
    Department of Bioengineering, University of Washington, Seattle, WA 98195, USA
    J Physiol 540:485-97. 2002
  6. ncbi request reprint Molecular and cellular aspects of muscle contraction. General discussion part II
    A M Gordon
    Department of Physiology and Biophysics, University of Washington, Seattle 98195 7290, USA
    Adv Exp Med Biol 538:661-9, 687-8. 2003
  7. ncbi request reprint Skeletal and cardiac muscle contractile activation: tropomyosin "rocks and rolls"
    A M Gordon
    Department of Physiology and Biophysics, University of Washington, Seattle, WA, USA
    News Physiol Sci 16:49-55. 2001
  8. pmc Influence of length on force and activation-dependent changes in troponin c structure in skinned cardiac and fast skeletal muscle
    D A Martyn
    Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA
    Biophys J 80:2798-808. 2001
  9. pmc A simple model with myofilament compliance predicts activation-dependent crossbridge kinetics in skinned skeletal fibers
    D A Martyn
    Department of Bioengineering, Box 357962, University of Washington, Seattle, WA 98195, USA
    Biophys J 83:3425-34. 2002
  10. pmc Ca2+ - and cross-bridge-dependent changes in N- and C-terminal structure of troponin C in rat cardiac muscle
    D A Martyn
    Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA
    Biophys J 80:360-70. 2001

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Cooperative activation of skeletal and cardiac muscle
    A M Gordon
    Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, USA
    Adv Exp Med Biol 538:371-8; discussion 378-9. 2003
  2. pmc Calcium regulation of skeletal muscle thin filament motility in vitro
    A M Gordon
    Department of Physiology and Biophysics, University of Washington, Seattle 98195, USA
    Biophys J 72:1295-307. 1997
    ..Comparison of motility results with the force-pCa relationship in fibers suggests that relatively few cross-bridges are needed to make filaments move, but many have to be cycling to make the regulated filament move at maximum speed...
  3. ncbi request reprint Regulation of contraction in striated muscle
    A M Gordon
    Department of Physiology and Biophysics, University of Washington, Seattle, Washington 98195 7290, USA
    Physiol Rev 80:853-924. 2000
    ..9) Different Tn subunit isoforms can modulate the cross-bridge detachment rate as shown by studies with mutant regulatory proteins in myotubes and in in vitro motility assays. (ABSTRACT TRUNCATED)..
  4. pmc Ca2+ regulation of rabbit skeletal muscle thin filament sliding: role of cross-bridge number
    Bo Liang
    Department of Physiology and Biophysics, University of Washington, Seattle, Washington 98195, USA
    Biophys J 85:1775-86. 2003
    ..These data are consistent with unloaded filament sliding speed being limited by the number of cycling cross-bridges so that maximal speed is attained with a critical, low level of actomyosin interactions...
  5. pmc Thin filament near-neighbour regulatory unit interactions affect rabbit skeletal muscle steady-state force-Ca(2+) relations
    Michael Regnier
    Department of Bioengineering, University of Washington, Seattle, WA 98195, USA
    J Physiol 540:485-97. 2002
    ..The results suggest that cooperative activation of skeletal muscle fibres occurs primarily through spread of activation to near-neighbour FUs along the thin filament (via head-to-tail tropomyosin interactions)...
  6. ncbi request reprint Molecular and cellular aspects of muscle contraction. General discussion part II
    A M Gordon
    Department of Physiology and Biophysics, University of Washington, Seattle 98195 7290, USA
    Adv Exp Med Biol 538:661-9, 687-8. 2003
  7. ncbi request reprint Skeletal and cardiac muscle contractile activation: tropomyosin "rocks and rolls"
    A M Gordon
    Department of Physiology and Biophysics, University of Washington, Seattle, WA, USA
    News Physiol Sci 16:49-55. 2001
    ..Variations in activation properties account for functional differences between these muscle types...
  8. pmc Influence of length on force and activation-dependent changes in troponin c structure in skinned cardiac and fast skeletal muscle
    D A Martyn
    Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA
    Biophys J 80:2798-808. 2001
    ..On the other hand, in cardiac muscle, both force and activation-dependent changes in cTnC structure were influenced by SL. Additionally, the effect of SL on cardiac muscle activation was itself dependent on active, cycling cross-bridges...
  9. pmc A simple model with myofilament compliance predicts activation-dependent crossbridge kinetics in skinned skeletal fibers
    D A Martyn
    Department of Bioengineering, Box 357962, University of Washington, Seattle, WA 98195, USA
    Biophys J 83:3425-34. 2002
    ....
  10. pmc Ca2+ - and cross-bridge-dependent changes in N- and C-terminal structure of troponin C in rat cardiac muscle
    D A Martyn
    Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA
    Biophys J 80:360-70. 2001
    ..These data suggest that both Ca2+ and cycling cross-bridges perturb the N-terminal structure of cTnC at Cys-84, while C-terminal structure is altered by site II Ca2+-binding, but not cross-bridges...
  11. pmc Ca2+ and cross-bridge-induced changes in troponin C in skinned skeletal muscle fibers: effects of force inhibition
    D A Martyn
    Department of Bioengineering, University of Washington, Seattle, Washington 98195 USA
    Biophys J 76:1480-93. 1999
    ..66 +/- 0.04 of pCa 4.0 control. These results indicate that cross-bridge binding in the rigor state alters sTnC structure, whereas cycling cross-bridges have little influence at either submaximum or maximum activating [Ca2+]...
  12. ncbi request reprint Motility assays of calcium regulation of actin filaments
    M A LaMadrid
    Dept of Physiology and Biophysics, Dept of Radiology, University of Washington, Seattle, Washington 98195, USA
    Results Probl Cell Differ 36:133-48. 2002
  13. ncbi request reprint Familial hypertrophic cardiomyopathy mutations in troponin I (K183D, G203S, K206Q) enhance filament sliding
    Jan Kohler
    Molekular und Zellphysiologie, Medizinische Hochschule, D 30625 Hannover, Germany
    Physiol Genomics 14:117-28. 2003
    ....