John Gorcsan

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi Echocardiography for cardiac resynchronization therapy: recommendations for performance and reporting--a report from the American Society of Echocardiography Dyssynchrony Writing Group endorsed by the Heart Rhythm Society
    John Gorcsan
    University of Pittsburgh, Pittsburgh, Pennsylvania 15213 2582, USA
    J Am Soc Echocardiogr 21:191-213. 2008
  2. ncbi Ventricular resynchronization is the principle mechanism of benefit with cardiac resynchronization therapy
    John Gorcsan
    University of Pittsburgh, Scaife 564, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Heart Fail Rev 17:737-46. 2012
  3. ncbi The role of tissue Doppler and strain imaging in predicting response to CRT
    John Gorcsan
    The Cardiovascular Institute, University of Pittsburgh, Scaife Hall 564, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Europace 10:iii80-7. 2008
  4. ncbi Cardiac resynchronization in 2008: an echo approach
    John Gorcsan
    The Cardiovascular Institute, University of Pittsburgh, Scaife Hall 564, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Curr Cardiol Rep 10:211-7. 2008
  5. ncbi Relationship of echocardiographic dyssynchrony to long-term survival after cardiac resynchronization therapy
    John Gorcsan
    University of Pittsburgh, Scaife 564, 200 Lothrop St, Pittsburgh, PA 15213 2582, USA
    Circulation 122:1910-8. 2010
  6. ncbi Combined longitudinal and radial dyssynchrony predicts ventricular response after resynchronization therapy
    John Gorcsan
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 2582, USA
    J Am Coll Cardiol 50:1476-83. 2007
  7. ncbi Left ventricular mechanical dyssynchrony in acute onset cardiomyopathy: association of its resolution with improvements in ventricular function
    Hidekazu Tanaka
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    JACC Cardiovasc Imaging 4:445-56. 2011
  8. ncbi Echocardiographic assessment of myocardial strain
    John Gorcsan
    University of Pittsburgh, Pittsburgh, PA, USA
    J Am Coll Cardiol 58:1401-13. 2011
  9. ncbi Role of echocardiography to determine candidacy for cardiac resynchronization therapy
    John Gorcsan
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 2582, USA
    Curr Opin Cardiol 23:16-22. 2008
  10. ncbi Echocardiographic assessment of ventricular dyssynchrony
    John Gorcsan
    University of Pittsburgh, Scaife Hall 564, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Curr Heart Fail Rep 5:31-7. 2008

Research Grants

  1. CARDIAC PERFORMANCE BY QUANTITATIVE ECHOCARDIOGRAPHY
    John Gorcsan; Fiscal Year: 2007
  2. Identifying and Facilitating Ventricular Recovery on Mechanical Support
    John Gorcsan; Fiscal Year: 2007
  3. Identifying and Facilitating Ventricular Recovery on Mechanical Support
    John Gorcsan; Fiscal Year: 2009

Detail Information

Publications76

  1. ncbi Echocardiography for cardiac resynchronization therapy: recommendations for performance and reporting--a report from the American Society of Echocardiography Dyssynchrony Writing Group endorsed by the Heart Rhythm Society
    John Gorcsan
    University of Pittsburgh, Pittsburgh, Pennsylvania 15213 2582, USA
    J Am Soc Echocardiogr 21:191-213. 2008
    ..Since this is rapidly changing field with new information being added frequently, future modification and refinements in approach are anticipated to continue...
  2. ncbi Ventricular resynchronization is the principle mechanism of benefit with cardiac resynchronization therapy
    John Gorcsan
    University of Pittsburgh, Scaife 564, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Heart Fail Rev 17:737-46. 2012
    ..However, the weight of evidence from a pathophysiological basis to the recent long-term patient outcome data strongly support the notion that resynchronization is the principle mechanism of benefit from CRT...
  3. ncbi The role of tissue Doppler and strain imaging in predicting response to CRT
    John Gorcsan
    The Cardiovascular Institute, University of Pittsburgh, Scaife Hall 564, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Europace 10:iii80-7. 2008
    ..The prevailing hypothesis is that echocardiography may be superior to the electrocardiogram to qualify abnormalities in regional mechanical activation, because QRS widening is only a surrogate for ventricular dyssynchrony...
  4. ncbi Cardiac resynchronization in 2008: an echo approach
    John Gorcsan
    The Cardiovascular Institute, University of Pittsburgh, Scaife Hall 564, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Curr Cardiol Rep 10:211-7. 2008
    ..Echocardiographic assessment of dyssynchrony continues to evolve, with new information being added continually, and appears to have promise for future clinical applications...
  5. ncbi Relationship of echocardiographic dyssynchrony to long-term survival after cardiac resynchronization therapy
    John Gorcsan
    University of Pittsburgh, Scaife 564, 200 Lothrop St, Pittsburgh, PA 15213 2582, USA
    Circulation 122:1910-8. 2010
    ..The ability of echocardiographic dyssynchrony to predict response to cardiac resynchronization therapy (CRT) has been unclear...
  6. ncbi Combined longitudinal and radial dyssynchrony predicts ventricular response after resynchronization therapy
    John Gorcsan
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 2582, USA
    J Am Coll Cardiol 50:1476-83. 2007
    ....
  7. ncbi Left ventricular mechanical dyssynchrony in acute onset cardiomyopathy: association of its resolution with improvements in ventricular function
    Hidekazu Tanaka
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    JACC Cardiovasc Imaging 4:445-56. 2011
    ..The purpose of this study was to evaluate mechanical dyssynchrony in patients with acute onset cardiomyopathy with narrow QRS interval, and its association with improvements in left ventricular (LV) function...
  8. ncbi Echocardiographic assessment of myocardial strain
    John Gorcsan
    University of Pittsburgh, Pittsburgh, PA, USA
    J Am Coll Cardiol 58:1401-13. 2011
    ....
  9. ncbi Role of echocardiography to determine candidacy for cardiac resynchronization therapy
    John Gorcsan
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 2582, USA
    Curr Opin Cardiol 23:16-22. 2008
    ....
  10. ncbi Echocardiographic assessment of ventricular dyssynchrony
    John Gorcsan
    University of Pittsburgh, Scaife Hall 564, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Curr Heart Fail Rep 5:31-7. 2008
    ..This article reviews current echocardiographic methods to quantify ventricular dyssynchrony, their strengths and limitations, and the proposed and potential expanding clinical applications...
  11. ncbi Comparative mechanical activation mapping of RV pacing to LBBB by 2D and 3D speckle tracking and association with response to resynchronization therapy
    Hidekazu Tanaka
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    JACC Cardiovasc Imaging 3:461-71. 2010
    ....
  12. ncbi Quantifying the role of regional dyssynchrony on global left ventricular performance
    Bouchra Lamia
    Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    JACC Cardiovasc Imaging 2:1350-6. 2009
    ....
  13. ncbi Relation of elevation in cardiac troponin I to clinical severity, cardiac dysfunction, and pulmonary congestion in patients with subarachnoid hemorrhage
    Masaki Tanabe
    Division of Cardiology, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Cardiol 102:1545-50. 2008
    ..Even mild increases in cTnI were associated with diastolic dysfunction and pulmonary congestion...
  14. ncbi Quantification of radial mechanical dyssynchrony in patients with left bundle branch block and idiopathic dilated cardiomyopathy without conduction delay by tissue displacement imaging
    L Elif Sade
    Division of Cardiology, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213-2582, USA
    Am J Cardiol 94:514-8. 2004
    ..001 vs normal). An interesting subset of patients with IDC without conduction delay (36%) had dyssynchrony with anteroseptal to posterior wall delays of 169 +/- 56 ms (p <0.001 vs normal), similar to patients with LBBB...
  15. ncbi Benefit of cardiac resynchronization therapy to a patient with a narrow QRS complex and ventricular dyssynchrony identified by tissue synchronization imaging
    Kaoru Dohi
    University of Pittsburgh, Scaife 564, 200 Lothrop Street, Pittsburgh, PA 15213-2582, USA
    Eur J Echocardiogr 6:455-60. 2005
    ..Echocardiographic tissue synchronization imaging may play a role in identifying mechanical dyssynchrony in patients with narrow QRS duration who may potentially benefit from cardiac resynchronization therapy...
  16. ncbi Right ventricular function following cardiac resynchronization therapy
    Navin Rajagopalan
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Am J Cardiol 100:1434-6. 2007
    ..In conclusion, CRT resulted in improved RV function measured as RV S(m). CRT had beneficial effects on RV function independent of improvement in left ventricular ejection fraction...
  17. ncbi Usefulness of echocardiographic tissue synchronization imaging to predict acute response to cardiac resynchronization therapy
    John Gorcsan
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 93:1178-81. 2004
    ..Although a subgroup without acute improvement had later decreases in end-systolic volume, suggesting that acute response underestimates long-term effects, TSI has potential to assist in guiding CRT...
  18. ncbi A mechanism for immediate reduction in mitral regurgitation after cardiac resynchronization therapy: insights from mechanical activation strain mapping
    Hideaki Kanzaki
    University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213-2582, USA
    J Am Coll Cardiol 44:1619-25. 2004
    ..Improved coordinated timing of mechanical activation of papillary muscle insertion sites appears to be a mechanistic contributor to immediate MR reduction by CRT...
  19. ncbi Dynamic and site-specific impact of ventricular pacing on left ventricular ejection fraction
    David Schwartzman
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Heart Rhythm 7:813-9. 2010
    ..Interactions between pacing site and LVEF remain unclear...
  20. ncbi The relationship of QRS morphology and mechanical dyssynchrony to long-term outcome following cardiac resynchronization therapy
    Hideyuki Hara
    The Cardiovascular Institute, University of Pittsburgh, Scaife 564, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Eur Heart J 33:2680-91. 2012
    ....
  21. ncbi Effect of concordance between sites of left ventricular pacing and dyssynchrony on acute electrocardiographic and echocardiographic parameters in patients with heart failure undergoing cardiac resynchronization therapy
    Maninder Bedi
    Cardiovascular Electrophysiology Section, Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Clin Cardiol 29:498-502. 2006
    ..The effect of concordance on the intermediate and long-term response to BIV pacing deserves further evaluation...
  22. ncbi Differential effects of left ventricular pacing sites in an acute canine model of contraction dyssynchrony
    Lauren Johnson
    Cardiovascular Systems Laboratory, Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Physiol Heart Circ Physiol 293:H3046-55. 2007
    ..The dissociation between changes in synchrony and global LV performance with CRTf suggests that regional analysis from a single plane may not be sufficient to adequately characterize contraction synchrony...
  23. ncbi Usefulness of echocardiographic dyssynchrony in patients with borderline QRS duration to assist with selection for cardiac resynchronization therapy
    Olusegun Oyenuga
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    JACC Cardiovasc Imaging 3:132-40. 2010
    ..To test the hypothesis that echocardiographic dyssynchrony may assist in the selection of patients with borderline QRS duration for cardiac resynchronization therapy (CRT)...
  24. ncbi A novel two-dimensional echocardiographic image analysis system using artificial intelligence-learned pattern recognition for rapid automated ejection fraction
    Maxime Cannesson
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 2582, USA
    J Am Coll Cardiol 49:217-26. 2007
    ..We sought to test the hypothesis that a novel 2-dimensional echocardiographic image analysis system using artificial intelligence-learned pattern recognition can rapidly and reproducibly calculate ejection fraction (EF)...
  25. ncbi Velocity vector imaging to quantify ventricular dyssynchrony and predict response to cardiac resynchronization therapy
    Maxime Cannesson
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 98:949-53. 2006
    ..Baseline electrocardiographic QRS duration was not predictive in the same patients. In conclusion, echocardiographic velocity vector imaging has potential for clinical utility...
  26. ncbi Effects of radial left ventricular dyssynchrony on cardiac performance using quantitative tissue Doppler radial strain imaging
    Kaoru Dohi
    Division of Cardiovascular Disease, Critical Care Medicine Department, University of Pittsburgh, Pittsburgh, Pennsylvania 15213-2582, USA
    J Am Soc Echocardiogr 19:475-82. 2006
    ..05 individually, r = 0.80 overall) and stroke work (r = -0.88 +/- 0.12 individually, r = -0.82 overall). Angle-corrected radial strain imaging has clinical potential to quantify mechanical dyssynchrony and effects of biventricular pacing...
  27. ncbi Novel speckle-tracking radial strain from routine black-and-white echocardiographic images to quantify dyssynchrony and predict response to cardiac resynchronization therapy
    Matthew S Suffoletto
    The Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA 15213-2582, USA
    Circulation 113:960-8. 2006
    ..05). CONCLUSIONS: Speckle-tracking radial strain can quantify dyssynchrony and predict immediate and long-term response to CRT and has potential for clinical application...
  28. ncbi Effects of modulation of left ventricular contractile state and loading conditions on tissue Doppler myocardial performance index
    Maxime Cannesson
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA 15213-2582, USA
    Am J Physiol Heart Circ Physiol 290:H1952-9. 2006
    ..All the above increases and decreases and r values were significant (P < 0.05 vs. baseline). In conclusion, TD MPI can rapidly quantify alterations in LV contractile state but is affected by acute alterations in preload and afterload...
  29. ncbi Differential exercise performance on ventricular assist device support
    Marc A Simon
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Heart Lung Transplant 24:1506-12. 2005
    ..Patients on LVAD support have better exercise tolerance than BiVAD-supported patients. This highlights the importance of right ventricular function to exercise tolerance in HF patients, and may have implications for future VAD design...
  30. ncbi Utility of echocardiographic radial strain imaging to quantify left ventricular dyssynchrony and predict acute response to cardiac resynchronization therapy
    Kaoru Dohi
    University of Pittsburgh, Pennsylvania, USA
    Am J Cardiol 96:112-6. 2005
    ....
  31. ncbi Physiological relevance of quantifying segmental contraction synchrony
    Lauren Johnson
    Cardiovascular Systems Laboratory, Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Pacing Clin Electrophysiol 35:174-87. 2012
    ..We report the development and physiological relevance of a novel method to quantify LV segmental contraction synchrony...
  32. ncbi Echocardiographic speckle tracking radial strain imaging to assess ventricular dyssynchrony in a pacing model of resynchronization therapy
    Masaki Tanabe
    The Cardiovascular Institute and Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Am Soc Echocardiogr 21:1382-8. 2008
    ..Our aim was to assess a new speckle tracking regional strain algorithm by comparison with angle-corrected tissue Doppler (TD) in an animal model of left bundle branch block and cardiac resynchronization therapy...
  33. ncbi Elevated cardiac troponin I and relationship to persistence of electrocardiographic and echocardiographic abnormalities after aneurysmal subarachnoid hemorrhage
    Marilyn Hravnak
    University of Pittsburgh Schools of Nursing, Pittsburgh, PA, USA
    Stroke 40:3478-84. 2009
    ..We hypothesized that post-aSAH cardiac injury, detected by elevated cardiac troponin I (cTnI), is related to aSAH severity and associated with electrocardiographic and structural echocardiographic abnormalities that are persistent...
  34. ncbi Left ventricular remodeling and myocardial recovery on mechanical circulatory support
    Marc A Simon
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA, USA
    J Card Fail 16:99-105. 2010
    ..Myocardial recovery after ventricular assist devices (VAD) is rare but appears more common in nonischemic cardiomyopathies (NICM). We sought to evaluate left ventricular (LV) end diastolic diameter (LVEDD) for predicting recovery after VAD...
  35. ncbi Left ventricular assist device support and myocardial recovery in recent onset cardiomyopathy
    John P Boehmer
    Penn State University College of Medicine, Hershey, PA, USA
    J Card Fail 18:755-61. 2012
    ..Myocardial recovery is more evident in recent onset nonischemic cardiomyopathy (ROCM); however, the prevalence of BTR in this subset has not been addressed...
  36. ncbi Left ventricular systolic torsion correlates global cardiac performance during dyssynchrony and cardiac resynchronization therapy
    Bouchra Lamia
    Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, USA
    Am J Physiol Heart Circ Physiol 300:H853-8. 2011
    ..12, P = 0.61 and r = 0.08, P = 0.73, respectively). Thus, we conclude that LV torsion is primarily altered by dyssynchrony, and CRT that restores LV performance also restores torsion...
  37. ncbi Impact of scar burden by single-photon emission computed tomography myocardial perfusion imaging on patient outcomes following cardiac resynchronization therapy
    Evan C Adelstein
    Cardiovascular Institute, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Eur Heart J 32:93-103. 2011
    ..Ischaemic heart disease negatively impacts response to cardiac resynchronization therapy (CRT), yet the impact of infarct scar burden on clinical outcomes and its interaction with mechanical dyssynchrony have not been well described...
  38. ncbi Usefulness of three-dimensional speckle tracking strain to quantify dyssynchrony and the site of latest mechanical activation
    Hidekazu Tanaka
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 105:235-42. 2010
    ..05). In conclusion, 3-D speckle tracking can successfully quantify 3-D dyssynchrony and site the latest mechanical activation. This approach may play a clinical role in management of patients on CRT...
  39. ncbi Prediction of response to cardiac resynchronization therapy by speckle tracking echocardiography using different software approaches
    Hidekazu Tanaka
    University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    J Am Soc Echocardiogr 22:677-84. 2009
    ....
  40. ncbi Right ventricular dyssynchrony in patients with pulmonary hypertension is associated with disease severity and functional class
    Angel Lopez-Candales
    Cardiovascular Institute at the University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Cardiovasc Ultrasound 3:23. 2005
    ..Abnormalities in right ventricular function are known to occur in patients with pulmonary arterial hypertension...
  41. ncbi Influence of hand-carried ultrasound on bedside patient treatment decisions for consultative cardiology
    John Gorcsan
    University of Pittsburgh, Scaife Hall S 564, 200 Lothrop St, Pittsburgh, PA 15213, USA
    J Am Soc Echocardiogr 17:50-5. 2004
    ..91-0.96). Goal-directed HCU has the potential to influence bedside patient treatment decisions and expedite health care...
  42. ncbi Myocardial recovery using ventricular assist devices: prevalence, clinical characteristics, and outcomes
    Marc A Simon
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Circulation 112:I32-6. 2005
    ..For most BTR subjects presenting with acute inflammatory cardiomyopathy, ventricular recovery was maintained long-term. VAD support as BTR should be considered in the care of acute myocarditis and PPCM...
  43. ncbi Electrocardiographically concealed variation in left ventricular capture: a case with implications for resynchronization therapy in ischemic cardiomyopathy
    Sara R Grimley
    Cardiovascular Institute, University of Pittsburgh, Pennsylvania 15213, USA
    Heart Rhythm 3:739-42. 2006
  44. ncbi Influence of alterations in loading on mitral annular velocity by tissue Doppler echocardiography and its associated ability to predict filling pressures
    Didier C Jacques
    Division of Cardiology, University of Pittsburgh, 200 Lothrop St, Pittsburgh, PA 15213, USA
    Chest 126:1910-8. 2004
    ..E/E' was more predictive of LV filling pressures in the presence of diastolic dysfunction...
  45. ncbi Image-guided cardiac resynchronization
    David Schwartzman
    Cardiovascular Institute, University of Pittsburgh, UPMC Presbyterian, B535, Pittsburgh, PA 15213 2582, USA
    Europace 12:877-80. 2010
    ..To facilitate placement of left ventricular leads during cardiac resynchronization therapy system implantation...
  46. ncbi Measures of left ventricular dyssynchrony and the correlation to clinical and echocardiographic response after cardiac resynchronization therapy
    Raed Abdelhadi
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 102:598-601. 2008
    ..The change in longitudinal but not radial measures of LV dyssynchrony correlates with improved physical quality-of-life score in intermediate term follow-up...
  47. ncbi Predicting hyperresponse among pacemaker-dependent nonischemic cardiomyopathy patients upgraded to cardiac resynchronization
    Evan Adelstein
    Cardiovascular Institute at the University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Cardiovasc Electrophysiol 22:905-11. 2011
    ..We examined the clinical characteristics of pacemaker-dependent patients who exhibit hyperresponse (i.e., normalization of LV function) with CRT upgrade...
  48. ncbi Left ventricular pacing lead implantation: potential utility of multimodal image integration
    Orly Goitein
    Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Heart Rhythm 3:91-4. 2006
  49. ncbi Comparison of outcomes for patients with nonischemic cardiomyopathy taking intravenous inotropes versus those weaned from or never taking inotropes at cardiac resynchronization therapy
    Evan Adelstein
    Heart and Vascular Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Cardiol 110:857-61. 2012
    ..In conclusion, inotrope therapy before CRT is an important marker of adverse outcomes after implantation in patients with nonischemic cardiomyopathy, with inotrope dependence denoting irreversible end-stage HF unresponsive to CRT...
  50. ncbi A micro-ribonucleic acid signature associated with recovery from assist device support in 2 groups of patients with severe heart failure
    Ravi Ramani
    Heart and Vascular Institute, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    J Am Coll Cardiol 58:2270-8. 2011
    ....
  51. ncbi Regional correlation by color-coded tissue Doppler to quantify improvements in mechanical left ventricular synchrony after biventricular pacing therapy
    Hideaki Kanzaki
    Cardiovascular Institute, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213-2582, USA
    Am J Cardiol 92:752-5. 2003
    ..The synchrony index in patients with heart failure was less than that in controls at baseline (r = 0.60 +/- 0.13 vs 0.94 +/- 0.02; p <0.01), but improved at 6 months after CRT (r = 0.77 +/- 0.09; p <0.05 vs baseline)...
  52. ncbi Clinical and demographic predictors of outcomes in recent onset dilated cardiomyopathy: results of the IMAC (Intervention in Myocarditis and Acute Cardiomyopathy)-2 study
    Dennis M McNamara
    Cardiovascular Institute, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    J Am Coll Cardiol 58:1112-8. 2011
    ..We sought to determine clinical and demographic predictors of recovery of left ventricular function for subjects with recent onset cardiomyopathy (ROCM)...
  53. ncbi Dyssynchrony by speckle-tracking echocardiography and response to cardiac resynchronization therapy: results of the Speckle Tracking and Resynchronization (STAR) study
    Hidekazu Tanaka
    University of Pittsburgh, Scaife Hall 564, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Eur Heart J 31:1690-700. 2010
    ..The Speckle Tracking and Resynchronization (STAR) study used a prospective multi-centre design to test the hypothesis that speckle-tracking echocardiography can predict response to cardiac resynchronization therapy (CRT)...
  54. ncbi Impact of catheter ablation on pulmonary vein morphology and mechanical function
    David Schwartzman
    University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Cardiovasc Electrophysiol 15:161-7. 2004
    ..Although the magnitude of the increase infers a state of pulmonary vein stenosis, there have been no reports of direct visualization of the ablation zone...
  55. ncbi Meeting highlights of the 15th annual Scientific Sessions of the American Society of Echocardiography: June 26 to 30, 2004
    John Gorcsan
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Am Coll Cardiol 44:2111-6. 2004
    ....
  56. ncbi Utility of echocardiographic tissue synchronization imaging to redirect left ventricular lead placement for improved cardiac resynchronization therapy
    Kaoru Dohi
    University of Pittsburgh, Pittsburgh, Pennsylvania 15213-2582, USA
    Pacing Clin Electrophysiol 28:461-5. 2005
    ..Pacing at the new lead site resulted in a 30% increase in stroke volume and symptomatic improvement. TSI in this case redirected lead position in a clinical nonresponder, resulting in a favorable response to CRT...
  57. ncbi Ventricular arrhythmia risk after subarachnoid hemorrhage
    J Michael Frangiskakis
    Cardiovascular Institute, University of Pittsburgh Medical Center, S572 Scaife Hall, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Neurocrit Care 10:287-94. 2009
    ..Our objective was to test the relationships between QTc prolongation, VA, and survival after SAH...
  58. ncbi Positive effect of darbepoetin on peri-infarction remodeling in a porcine model of myocardial ischemia-reperfusion
    Catalin Toma
    Cardiovascular Institute, University of Pittsburgh Medical Center, Scaife Hall S559, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    J Mol Cell Cardiol 43:130-6. 2007
    ..Although the infarct size was not reduced, there was a limited decrease in interstitial fibrosis, increased capillary area and regional functional improvement in darbepoetin-treated animals...
  59. ncbi Second-generation tissue Doppler with angle-corrected color-coded wall displacement for quantitative assessment of regional left ventricular function
    L Elif Sade
    Division of Cardiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 92:554-60. 2003
    ..43) for visual assessment with caliper data as the standard of reference. Angle-corrected displacement imaging was superior to routine visual assessment and is a promising new method to quantify regional left ventricular function...
  60. ncbi Usefulness of angle corrected tissue Doppler to assess segmental left ventricular function during dobutamine stress echocardiography in patients with and without coronary artery disease
    L Elif Sade
    Cardiovascular Institute, University of Pittsburgh, Pennsylvania, USA
    Am J Cardiol 96:141-7. 2005
    ....
  61. ncbi A practical approach to imaging dyssynchrony for cardiac resynchronization therapy
    Olusegun A Oyenuga
    University of Pittsburgh, Scaife 564, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Heart Fail Rev 16:397-410. 2011
    ..The technical features, strengths and limitations, and clinical evidence for these methods are discussed, including a practical clinical approach...
  62. ncbi Non-invasive assessment of myocardial recovery on chronic left ventricular assist device: results associated with successful device removal
    John Gorcsan
    Division of Cardiology, University of Pittsburgh, S564 Scaife Hall, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    J Heart Lung Transplant 22:1304-13. 2003
    ..We hypothesized that on-line quantitative echocardiography during trials of decreased device support alone or in combination with exercise cardiopulmonary testing can assess cardiac recovery to predict successful device removal...
  63. ncbi Utility of hand-carried ultrasound for consultative cardiology
    John Gorcsan
    Division of Cardiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Echocardiography 20:463-9. 2003
    ..Hand-carried ultrasound has promise to have an immediate impact on bedside patient management though expediting and facilitating the delivery of medical care...
  64. ncbi Role of radial strain and displacement imaging to quantify wall motion dyssynchrony in patients with left ventricular mechanical dyssynchrony and chronic right ventricular pressure overload
    Kaoru Dohi
    Mie University Graduate School of Medicine, Tsu, Japan
    Am J Cardiol 101:1206-12. 2008
    ....
  65. ncbi American College of Cardiology/American Heart Association clinical competence statement on echocardiography: a report of the American College of Cardiology/American Heart Association/American College of Physicians--American Society of Internal Medicine Ta
    Miguel A Quinones
    Circulation 107:1068-89. 2003
  66. ncbi Results of the Predictors of Response to CRT (PROSPECT) trial
    Eugene S Chung
    Lindner Clinical Trial Center, Cincinnati, OH 45219, USA
    Circulation 117:2608-16. 2008
    ..In a prospective, multicenter setting, the Predictors of Response to CRT (PROSPECT) study tested the performance of these parameters to predict CRT response...
  67. ncbi Speckle-tracking radial strain reveals left ventricular dyssynchrony in patients with permanent right ventricular pacing
    Laurens F Tops
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 50:1180-8. 2007
    ..Speckle-tracking strain analysis was used to assess the effects of permanent right ventricular (RV) pacing on the heterogeneity in timing of regional wall strain and left ventricular (LV) dyssynchrony...
  68. ncbi Left ventricular dyssynchrony acutely after myocardial infarction predicts left ventricular remodeling
    Sjoerd A Mollema
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 50:1532-40. 2007
    ..We sought to identify predictors of left ventricular (LV) remodeling after acute myocardial infarction...
  69. ncbi Usefulness of tissue Doppler velocity and strain dyssynchrony for predicting left ventricular reverse remodeling response after cardiac resynchronization therapy
    Cheuk Man Yu
    Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Am J Cardiol 100:1263-70. 2007
    ..In conclusion, parameters of tissue Doppler longitudinal velocity, but not longitudinal strain, predicted LV reverse remodeling after CRT...
  70. ncbi Cardiac resynchronization therapy: Part 2--issues during and after device implantation and unresolved questions
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 46:2168-82. 2005
    ..Finally, open questions concerning when to combine CRT with implantable cardioverter-defibrillator therapy and the cost-effectiveness of CRT are discussed...
  71. ncbi Cardiac resynchronization therapy: Part 1--issues before device implantation
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 46:2153-67. 2005
    ..In addition, the value of LV scar tissue and venous anatomy for the selection of potential candidates for CRT are discussed...
  72. ncbi Normal values of left ventricular systolic and diastolic function derived from signal-averaged acoustic quantification waveforms: a multicenter study
    Kirk T Spencer
    Section of Cardiology, University of Chicago, Medical Center, Illinois 60637, USA
    J Am Soc Echocardiogr 16:1244-51. 2003
    ....
  73. ncbi Meeting highlights of the 14th annual scientific sessions of the American Society of Echocardiography: June 11 to 14, 2003, in Las Vegas, Nevada
    Linda D Gillam
    Hartford Hospital, Hartford, Connecticut 06102-8000, USA
    J Am Coll Cardiol 42:2149-55. 2003
  74. ncbi ACC/AHA clinical competence statement on echocardiography: a report of the American College of Cardiology/American Heart Association/American College of Physicians-American Society of Internal Medicine Task Force on clinical competence
    Miguel A Quinones
    J Am Soc Echocardiogr 16:379-402. 2003
  75. ncbi ACC/AHA clinical competence statement on echocardiography: a report of the American College of Cardiology/American Heart Association/American College of Physicians-American Society of Internal Medicine Task Force on Clinical Competence
    Miguel A Quinones
    J Am Coll Cardiol 41:687-708. 2003
  76. ncbi Guidelines and recommendations for digital echocardiography
    James D Thomas
    American Society of Echocardiography, 1500 Sunday Drive, Suite 102, Raleigh, NC 27607, USA
    J Am Soc Echocardiogr 18:287-97. 2005

Research Grants7

  1. CARDIAC PERFORMANCE BY QUANTITATIVE ECHOCARDIOGRAPHY
    John Gorcsan; Fiscal Year: 2007
    ..walk test, and ejection fraction) will be assessed at 6 mo. and 1 year. These studies will provide valuable insight to the correct utilization of these extensive therapies and provide abundant opportunities for mentoring of trainees. ..
  2. Identifying and Facilitating Ventricular Recovery on Mechanical Support
    John Gorcsan; Fiscal Year: 2007
    ..We will use novel non-invasive cardiac testing to identify recovery of the heart on LVAD and develop a unique control system to facilitate cardiac recovery. ..
  3. Identifying and Facilitating Ventricular Recovery on Mechanical Support
    John Gorcsan; Fiscal Year: 2009
    ..We will use novel non-invasive cardiac testing to identify recovery of the heart on LVAD and develop a unique control system to facilitate cardiac recovery. ..