MICHAEL ISAAC GORAN

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi request reprint Interactive multimedia for promoting physical activity (IMPACT) in children
    Michael I Goran
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Obes Res 13:762-71. 2005
  2. pmc Subcutaneous adipose tissue macrophage infiltration is associated with hepatic and visceral fat deposition, hyperinsulinemia, and stimulation of NF-κB stress pathway
    Kim Anne Le
    Department of Preventive Medicine, Childhood Obesity Research Center, University of Southern California, Los Angeles, California, USA
    Diabetes 60:2802-9. 2011
  3. pmc Ethnic differences in pancreatic fat accumulation and its relationship with other fat depots and inflammatory markers
    Kim Anne Le
    Department of Preventive Medicine, Childhood Obesity Research Center, University of Southern California, Los Angeles, California, USA
    Diabetes Care 34:485-90. 2011
  4. pmc Insulin sensitivity as an independent predictor of fat mass gain in Hispanic adolescents
    Tanja C Adam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Diabetes Care 32:2114-5. 2009
  5. pmc Combined association of maternal and paternal family history of diabetes with plasma leptin and adiponectin in overweight Hispanic children
    C Koebnick
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089 9008, USA
    Diabet Med 25:1043-8. 2008
  6. doi request reprint The obesogenic effect of high fructose exposure during early development
    Michael I Goran
    Department of Preventive Medicine and Childhood Obesity Research Centre, University of Southern California, 2250 Alcazar Street, Los Angeles, CA 90089, USA
    Nat Rev Endocrinol 9:494-500. 2013
  7. pmc Liver fat has a stronger association with risk factors for type 2 diabetes in African-American compared with Hispanic adolescents
    Tanya L Alderete
    University of Southern California, Department of Preventive Medicine, Childhood Obesity Research Center, 2250 Alcazar Street, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 98:3748-54. 2013
  8. ncbi request reprint High rates of fructose malabsorption are associated with reduced liver fat in obese African Americans
    Ryan W Walker
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    J Am Coll Nutr 31:369-74. 2012
  9. doi request reprint High fructose corn syrup and diabetes prevalence: a global perspective
    Michael I Goran
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA
    Glob Public Health 8:55-64. 2013
  10. doi request reprint Targeting adipose tissue inflammation to treat the underlying basis of the metabolic complications of obesity
    Michael I Goran
    Department of Preventive Medicine and Childhood Obesity Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Nestle Nutr Inst Workshop Ser 73:49-60; discussion p61-6. 2012

Research Grants

  1. INTRA-ABDOMINAL FAT AND RISK OF DISEASE IN ADOLESCENTS
    Michael Goran; Fiscal Year: 2005
  2. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2006
  3. INTRA-ABDOMINAL FAT AND RISK OF DISEASE IN ADOLESCENTS
    Michael Goran; Fiscal Year: 2006
  4. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2007
  5. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2006
  6. INTRA-ABDOMINAL FAT AND RISK OF DISEASE IN ADOLESCENTS
    Michael Goran; Fiscal Year: 2007
  7. USC Center for Transdisciplinary Research on Energetics*
    Michael Goran; Fiscal Year: 2007
  8. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2009
  9. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2004
  10. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2005

Detail Information

Publications94

  1. ncbi request reprint Interactive multimedia for promoting physical activity (IMPACT) in children
    Michael I Goran
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Obes Res 13:762-71. 2005
    ..To develop and examine the efficacy of a computer-based interactive multimedia curriculum for promoting physical activity in fourth grade children...
  2. pmc Subcutaneous adipose tissue macrophage infiltration is associated with hepatic and visceral fat deposition, hyperinsulinemia, and stimulation of NF-κB stress pathway
    Kim Anne Le
    Department of Preventive Medicine, Childhood Obesity Research Center, University of Southern California, Los Angeles, California, USA
    Diabetes 60:2802-9. 2011
    ....
  3. pmc Ethnic differences in pancreatic fat accumulation and its relationship with other fat depots and inflammatory markers
    Kim Anne Le
    Department of Preventive Medicine, Childhood Obesity Research Center, University of Southern California, Los Angeles, California, USA
    Diabetes Care 34:485-90. 2011
    ..Our aim was to assess ethnic and sex differences in PFF and its relationship to other fat depots, circulating free fatty acids (FFA), insulin secretion and sensitivity, and inflammation in obese adolescents and young adults...
  4. pmc Insulin sensitivity as an independent predictor of fat mass gain in Hispanic adolescents
    Tanja C Adam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Diabetes Care 32:2114-5. 2009
    ..The purpose of this study was to examine the relationship between changes in insulin sensitivity and subsequent changes in fat mass in obese Hispanic children over 3 consecutive years...
  5. pmc Combined association of maternal and paternal family history of diabetes with plasma leptin and adiponectin in overweight Hispanic children
    C Koebnick
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089 9008, USA
    Diabet Med 25:1043-8. 2008
    ....
  6. doi request reprint The obesogenic effect of high fructose exposure during early development
    Michael I Goran
    Department of Preventive Medicine and Childhood Obesity Research Centre, University of Southern California, 2250 Alcazar Street, Los Angeles, CA 90089, USA
    Nat Rev Endocrinol 9:494-500. 2013
    ..These changes ultimately favour the long-term development of obesity and associated metabolic risk. ..
  7. pmc Liver fat has a stronger association with risk factors for type 2 diabetes in African-American compared with Hispanic adolescents
    Tanya L Alderete
    University of Southern California, Department of Preventive Medicine, Childhood Obesity Research Center, 2250 Alcazar Street, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 98:3748-54. 2013
    ..Although overweight and obese African-Americans (AAs) have less visceral adipose tissue (VAT) and liver fat (LF) than Hispanics, they have a similar risk for type 2 diabetes...
  8. ncbi request reprint High rates of fructose malabsorption are associated with reduced liver fat in obese African Americans
    Ryan W Walker
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    J Am Coll Nutr 31:369-74. 2012
    ..We hypothesized that fructose malabsorption in African Americans may reduce hepatic delivery of fructose, thus contributing to lower liver fat deposition compared to Hispanics...
  9. doi request reprint High fructose corn syrup and diabetes prevalence: a global perspective
    Michael I Goran
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA
    Glob Public Health 8:55-64. 2013
    ..5.22 mmol/L, p=0.03) despite similarities in obesity and total sugar and calorie availability. These results suggest that countries with higher availability of HFCS have a higher prevalence of type 2 diabetes independent of obesity...
  10. doi request reprint Targeting adipose tissue inflammation to treat the underlying basis of the metabolic complications of obesity
    Michael I Goran
    Department of Preventive Medicine and Childhood Obesity Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Nestle Nutr Inst Workshop Ser 73:49-60; discussion p61-6. 2012
    ..In this paper, we will review the hypothesis linking excess adipose tissue to increased disease risk through adipose tissue inflammation...
  11. pmc Genetic-related and carbohydrate-related factors affecting liver fat accumulation
    Michael I Goran
    Department of Preventive Medicine, Childhood Obesity Research Center, Keck School of Medicine, The University of Southern California, Los Angeles, California, USA
    Curr Opin Clin Nutr Metab Care 15:392-6. 2012
    ..In addition, this review highlights how some of these contributions to liver fat vary across the population in terms of ethnic-specific effects...
  12. pmc Validity of new child-specific thoracic gas volume prediction equations for air-displacement plethysmography
    Paul B Higgins
    Department of Nutrition Sciences, University of Alabama at Birmingham, AL, USA
    BMC Pediatr 6:18. 2006
    ..To determine the validity of the recently developed child-specific thoracic gas volume (TGV) prediction equations for use in air-displacement plethysmography (ADP) in diverse pediatric populations...
  13. pmc Fasting indicators of insulin sensitivity: effects of ethnicity and pubertal status
    Tanja C Adam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Diabetes Care 34:994-9. 2011
    ....
  14. pmc Deterioration of insulin sensitivity and beta-cell function in overweight Hispanic children during pubertal transition: a longitudinal assessment
    Michael I Goran
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
    Int J Pediatr Obes 1:139-45. 2006
    ..To examine 1-year changes in insulin dynamics in overweight Hispanic children at high-risk of type 2 diabetes as a function of body composition and pubertal transition...
  15. pmc Low prevalence of pediatric type 2 diabetes: where's the epidemic?
    Michael I Goran
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089 9008, USA
    J Pediatr 152:753-5. 2008
  16. pmc Effects of PNPLA3 on liver fat and metabolic profile in Hispanic children and adolescents
    Michael I Goran
    Department of Preventive Medicine, Childhood Obesity Research Center, University of Southern California, Los Angeles, California, USA
    Diabetes 59:3127-30. 2010
    ..The purpose of this study was to examine the influence of PNPLA3 genotype on liver fat and other related metabolic outcomes in obese Hispanic children and adolescents...
  17. ncbi request reprint Impaired glucose tolerance and reduced beta-cell function in overweight Latino children with a positive family history for type 2 diabetes
    Michael I Goran
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 89:207-12. 2004
    ....
  18. pmc Persistence of pre-diabetes in overweight and obese Hispanic children: association with progressive insulin resistance, poor beta-cell function, and increasing visceral fat
    Michael I Goran
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Diabetes 57:3007-12. 2008
    ..To examine changes in risk factors in overweight and obese Hispanic children at high risk of developing type 2 diabetes...
  19. ncbi request reprint Estimating energy requirements: regression based prediction equations or multiples of resting metabolic rate
    Michael I Goran
    Institute for Prevention Research and Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Public Health Nutr 8:1184-6. 2005
    ..Its major departure from tradition, difference from current adult proposals, and time taken for acceptance are the disadvantages of the regression-based approach...
  20. ncbi request reprint Obesity and risk of type 2 diabetes and cardiovascular disease in children and adolescents
    Michael I Goran
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 88:1417-27. 2003
    ..Therefore, the purpose of this paper is to review the pathophysiology of type 2 diabetes and cardiovascular risk in obese children and adolescents...
  21. ncbi request reprint Influence of family history of type 2 diabetes on insulin sensitivity in prepubertal children
    Michael I Goran
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 88:192-5. 2003
    ..In conclusion, a positive FH for T2D does not seem to have any significant effect on insulin sensitivity, as assessed by the minimal model and associated risk factors for T2D in young children...
  22. ncbi request reprint Insulin resistance and associated compensatory responses in african-american and Hispanic children
    Michael I Goran
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
    Diabetes Care 25:2184-90. 2002
    ..The objective of this study was to compare insulin resistance relative to body fat and the associated compensatory responses in 57 healthy children living in Los Angeles, California (14 Caucasians, 15 African-Americans, and 28 Hispanics)...
  23. ncbi request reprint Energy expenditure, physical activity, and obesity in children
    M I Goran
    Institute for Prevention Research, Departments of Preventive Medicine and Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Pediatr Clin North Am 48:931-53. 2001
    ..These prevention efforts should begin in childhood because the behaviors are learned and continue through the lifetime...
  24. ncbi request reprint Metabolic precursors and effects of obesity in children: a decade of progress, 1990-1999
    M I Goran
    Institute for Prevention Research, The Department of Preventive Medicine, University of Southern California, Los Angeles, USA
    Am J Clin Nutr 73:158-71. 2001
    ....
  25. ncbi request reprint Longitudinal study on pubertal insulin resistance
    M I Goran
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Diabetes 50:2444-50. 2001
    ..The significant fall in DI suggests conservation in beta-cell function or an inadequate beta-cell response to the fall in S(I). The fall in S(I) was not associated with changes in body fat, visceral fat, IGF-I, androgens, or estradiol...
  26. ncbi request reprint Influence of total vs. visceral fat on insulin action and secretion in African American and white children
    M I Goran
    Institute for Prevention Research, Department of Preventive Medicine, University of Southern California, Los Angeles, 90033, USA
    Obes Res 9:423-31. 2001
    ..To examine whether total body fat (FAT) in general or visceral fat (VFAT) in particular is associated with greater metabolic risk in white and African American children...
  27. ncbi request reprint The metabolic syndrome in overweight Hispanic youth and the role of insulin sensitivity
    Martha L Cruz
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    J Clin Endocrinol Metab 89:108-13. 2004
    ..Improving insulin resistance may be crucial for the prevention of chronic disease in this at-risk population...
  28. ncbi request reprint Development of a prediction equation for insulin sensitivity from anthropometry and fasting insulin in prepubertal and early pubertal children
    Terry T K Huang
    Institute for Health Promotion and Disease Prevention Research, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Diabetes Care 25:1203-10. 2002
    ....
  29. ncbi request reprint Association between insulin sensitivity and post-glucose challenge plasma insulin values in overweight Latino youth
    Marc J Weigensberg
    Department of Physiology and Biophysics, University of Southern California, Los Angeles, California 90089, USA
    Diabetes Care 26:2094-9. 2003
    ....
  30. pmc Ethnic differences in insulin action in obese African-American and Latino adolescents
    Rebecca E Hasson
    University of Southern California, Department of Preventive Medicine, 2250 Alcazar Street, Clinical Sciences Center, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 95:4048-51. 2010
    ..It is unclear whether African-Americans demonstrate an exaggerated insulin response to an oral glucose challenge and whether any differences are seen in more obese children in advanced pubertal development...
  31. pmc The relation of sugar intake to beta cell function in overweight Latino children
    Jaimie N Davis
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Am J Clin Nutr 82:1004-10. 2005
    ..Few studies have investigated the association between sugar intake and insulin dynamics in children, and none have examined this association in overweight Latino youth...
  32. pmc Dietary intake and the metabolic syndrome in overweight Latino children
    Emily E Ventura
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    J Am Diet Assoc 108:1355-9. 2008
    ..Increases in soluble fiber through the daily consumption of fruits, vegetables, and beans may improve metabolic health in Latino children...
  33. ncbi request reprint Longitudinal changes in insulin sensitivity, insulin secretion, and beta-cell function during puberty
    Geoff D C Ball
    Department of Preventive Medicine, University of Southern California, Los Angeles, USA
    J Pediatr 148:16-22. 2006
    ..To determine longitudinal changes in insulin sensitivity (SI), insulin secretion, and beta-cell function during puberty in white and black youth...
  34. ncbi request reprint Influence of breastfeeding on obesity and type 2 diabetes risk factors in Latino youth with a family history of type 2 diabetes
    Jaimie N Davis
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Diabetes Care 30:784-9. 2007
    ..To determine whether breastfeeding is related to total adiposity, regional adiposity, and glucose and insulin dynamics in overweight Latino youth throughout puberty...
  35. ncbi request reprint Effect of changes in fat distribution on the rates of change of insulin response in children
    Terry T K Huang
    Institute for Health Promotion and Disease Prevention Research, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Obes Res 10:978-84. 2002
    ....
  36. doi request reprint Birth weight and body composition in overweight Latino youth: a longitudinal analysis
    Louise A Kelly
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Obesity (Silver Spring) 16:2524-8. 2008
    ....
  37. ncbi request reprint Insulin sensitivity and blood pressure in black and white children
    Martha L Cruz
    Institute for Health Promotion and Disease Prevention Research and Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles 90089 9008, USA
    Hypertension 40:18-22. 2002
    ..In conclusion, the relationship between insulin sensitivity and systolic blood pressure is evident early in life. Black ethnicity and low insulin sensitivity contribute independently to higher blood pressure in children...
  38. ncbi request reprint Dietary fat intake and insulin resistance in black and white children
    Marc J Weigensberg
    Department of Pediatrics, University of Southern California, Los Angeles, CA 90089, USA
    Obes Res 13:1630-7. 2005
    ..The purpose of this study was to determine whether dietary fat intake above current Acceptable Macronutrient Distribution Range (AMDR) guidelines was associated with greater insulin resistance in black and white children...
  39. ncbi request reprint Decreased beta-cell function in overweight Latino children with impaired fasting glucose
    Marc J Weigensberg
    Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Diabetes Care 28:2519-24. 2005
    ..To determine whether overweight Latino children with impaired fasting glucose (IFG) (> or = 100 mg/dl) have increased insulin resistance or decreased beta-cell function compared with those with normal fasting glucose (NFG)...
  40. ncbi request reprint Insulin sensitivity, cardiorespiratory fitness, and physical activity in overweight Hispanic youth
    Geoff D C Ball
    Department of Preventive Medicine, Los Angeles County University of Southern California Medical Center, University of Southern California, Los Angeles, California 90089, USA
    Obes Res 12:77-85. 2004
    ..To determine whether cardiorespiratory fitness and/or physical activity (PA) were related to measures of insulin sensitivity and secretion independent of body composition in overweight Hispanic children...
  41. pmc Randomized control trial to improve adiposity and insulin resistance in overweight Latino adolescents
    Jaimie N Davis
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Obesity (Silver Spring) 17:1542-8. 2009
    ..In conclusion, this intense, culturally tailored intervention resulted in no significant intervention effects on measured risk factors with the exception of a beneficial effect on glycemic response to oral glucose...
  42. ncbi request reprint Influence of gender, BMI and Hispanic ethnicity on physical activity in children
    Courtney Byrd-Williams
    University of Southern California, Department of Preventive Medicine, Keck School of Medicine, and Institute for Prevention Research, Los Angeles, California 90033, USA
    Int J Pediatr Obes 2:159-66. 2007
    ..The purpose of this study was to examine the association between overweight status and physical activity (PA) among gender and ethnic (Hispanic vs. non-Hispanic) sub-groups in elementary school-age children...
  43. ncbi request reprint Unique effect of visceral fat on insulin sensitivity in obese Hispanic children with a family history of type 2 diabetes
    Martha L Cruz
    Departments of Preventive Medicine and Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Diabetes Care 25:1631-6. 2002
    ..This study aimed to establish whether total fat or central fat was related to measures of insulin in obese Hispanic children with a family history of type 2 diabetes...
  44. ncbi request reprint Feasibility of a home-based versus classroom-based nutrition intervention to reduce obesity and type 2 diabetes in Latino youth
    Jaimie N Davis
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Int J Pediatr Obes 2:22-30. 2007
    ....
  45. pmc Persistence of the metabolic syndrome over 3 annual visits in overweight Hispanic children: association with progressive risk for type 2 diabetes
    Emily E Ventura
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    J Pediatr 155:535-41. 2009
    ..To examine an association between persistent metabolic syndrome (MetS) and the risk for type 2 diabetes in overweight Hispanic children...
  46. ncbi request reprint Insulin-like growth factor-I is inversely related to adiposity in overweight Latino children
    Claudia M Toledo-Corral
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089 9073, USA
    J Pediatr Endocrinol Metab 21:855-64. 2008
    ..02, p = 0.85). Correlations with visceral and subcutaneous adipose tissue yielded similar results. These results demonstrate that IGF-I, IGFBP-1 and IGFBP-3 are all inversely related to adiposity in Hispanic children...
  47. pmc Cortisol is negatively associated with insulin sensitivity in overweight Latino youth
    Tanja C Adam
    University of Southern California, Department of Preventive Medicine, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 95:4729-35. 2010
    ..The purpose of the present study was to investigate the cross-sectional and longitudinal associations of serum morning cortisol and aspects of insulin action in Latino children and adolescents (8-13 yr) at risk for type 2 diabetes...
  48. ncbi request reprint Parental history and risk of type 2 diabetes in overweight Latino adolescents: a longitudinal analysis
    Louise A Kelly
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Diabetes Care 30:2700-5. 2007
    ....
  49. ncbi request reprint Relation between acanthosis nigricans and insulin sensitivity in overweight Hispanic children at risk for type 2 diabetes
    Hassan A Kobaissi
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Health Sciences Campus, 1540 Alcazar Street, Rm 208 D, Los Angeles, CA 90033, USA
    Diabetes Care 27:1412-6. 2004
    ....
  50. pmc Interventions for improving metabolic risk in overweight Latino youth
    Jaimie N Davis
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, USA
    Int J Pediatr Obes 5:451-5. 2010
    ..In conclusion, ST, CAST, and a modified carbohydrate nutrition program with separate parental classes were all successful components of the interventions that decreased obesity and related metabolic diseases...
  51. pmc Association of breakfast skipping with visceral fat and insulin indices in overweight Latino youth
    Katharine E Alexander
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Obesity (Silver Spring) 17:1528-33. 2009
    ..Eating breakfast is associated with lower visceral adiposity in overweight Latino youth. Interventions focused on increasing breakfast consumption are warranted...
  52. ncbi request reprint Ethnic disparity in the relationship between obesity and plasma insulin-like growth factors: the multiethnic cohort
    Katherine Delellis Henderson
    Keck School of Medicine, University of Southern California, Los Angeles, California 90033 0800, USA
    Cancer Epidemiol Biomarkers Prev 15:2298-302. 2006
    ....
  53. pmc Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption
    Jaimie N Davis
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Am J Clin Nutr 92:1522-7. 2010
    ..Animal models have also shown that PNPLA3 expression can be regulated by dietary carbohydrate...
  54. pmc A brief dietary screener: appropriate for overweight Latino adolescents?
    Jaimie N Davis
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 2250 Alcazar St, Building CSC, Suite 200, Los Angeles, CA 90033, USA
    J Am Diet Assoc 109:725-9. 2009
    ....
  55. pmc Acute effects of stress-reduction Interactive Guided Imagery(SM) on salivary cortisol in overweight Latino adolescents
    Marc J Weigensberg
    Department of Pediatrics, Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
    J Altern Complement Med 15:297-303. 2009
    ....
  56. ncbi request reprint Cardiovascular fitness and the metabolic syndrome in overweight latino youths
    Gabriel Q Shaibi
    Department of Biokinesiology and Physical Therapy, University of Southern California, Health Sciences Campus, Los Angeles, CA 90033, USA
    Med Sci Sports Exerc 37:922-8. 2005
    ..To determine whether cardiovascular fitness (.)VO(2max) is associated with the metabolic syndrome and its individual features in overweight Latino youths...
  57. pmc Reducing sedentary behavior in minority girls via a theory-based, tailored classroom media intervention
    Donna Spruijt-Metz
    Keck School of Medicine, University of Southern California, Alhambra, California 91803, USA
    Int J Pediatr Obes 3:240-8. 2008
    ..To develop, implement and test an innovative, theory-based classroom media intervention known as Get Moving! to increase physical activity and decrease sedentary behaviors in predominantly Latina middle school girls...
  58. pmc A high-sugar/low-fiber meal compared with a low-sugar/high-fiber meal leads to higher leptin and physical activity levels in overweight Latina females
    Donna Spruijt-Metz
    University of Southern California, Keck School of Medicine, USC IPR, 1000 S Fremont, Unit 8, Room 4101, Alhambra, CA 91803, USA
    J Am Diet Assoc 109:1058-63. 2009
    ..High-sugar meals sustain glucose and leptin levels longer, which may play an important role in modulating levels of physical activity in this group at high risk for obesity-related disease...
  59. pmc Association between the metabolic syndrome and serum cortisol in overweight Latino youth
    Marc J Weigensberg
    Department of Pediatrics, University of Southern California, 2250 Alcazar Street, CSC 200, Los Angeles, California 90089 9073, USA
    J Clin Endocrinol Metab 93:1372-8. 2008
    ..The purpose of this report is to investigate the associations between metabolic syndrome (MS) and levels of morning serum cortisol in a cohort of overweight Latino youth...
  60. pmc Aerobic and strength training reduces adiposity in overweight Latina adolescents
    Jaimie N Davis
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Med Sci Sports Exerc 41:1494-503. 2009
    ....
  61. ncbi request reprint The metabolic syndrome in children and adolescents
    Martha L Cruz
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, CHP Room 208 D, Los Angeles, CA 90089, USA
    Curr Diab Rep 4:53-62. 2004
    ..This article focuses on the above issues, as well as on the impact of the syndrome on two major disease outcomes, type 2 diabetes and cardiovascular disease...
  62. pmc Identification of brown adipose tissue in mice with fat-water IDEAL-MRI
    Houchun H Hu
    Ming Hsieh Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089 2564, USA
    J Magn Reson Imaging 31:1195-202. 2010
    ....
  63. ncbi request reprint Associations of dietary sugar and glycemic index with adiposity and insulin dynamics in overweight Latino youth
    Jaimie N Davis
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Am J Clin Nutr 86:1331-8. 2007
    ..Few studies have examined the relation between dietary carbohydrate quality, adiposity, and insulin dynamics in children...
  64. ncbi request reprint Relation between mothers' child-feeding practices and children's adiposity
    Donna Spruijt-Metz
    Department of Preventive Medicine, The University of Southern California, Alhambra, CA 91803, USA
    Am J Clin Nutr 75:581-6. 2002
    ..The prevalence of obesity in American children is currently estimated to be 25%. Poor nutritional habits during childhood have been directly related to pediatric obesity...
  65. pmc Comparison of fat-water MRI and single-voxel MRS in the assessment of hepatic and pancreatic fat fractions in humans
    Houchun H Hu
    Magnetic Resonance Engineering Laboratory, Ming Hsieh Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, California, USA
    Obesity (Silver Spring) 18:841-7. 2010
    ..We conclude that IDEAL is equally accurate in characterizing hepatic fat content as MRS, and is potentially better suited for fat quantification in smaller organs such as the pancreas...
  66. pmc Increased physical activity and reduced adiposity in overweight Hispanic adolescents
    Courtney E Byrd-Williams
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Med Sci Sports Exerc 42:478-84. 2010
    ....
  67. pmc Inverse relation between dietary fiber intake and visceral adiposity in overweight Latino youth
    Jaimie N Davis
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Am J Clin Nutr 90:1160-6. 2009
    ..To date, no studies have assessed the longitudinal changes of dietary intake on metabolic risk factors in Latino youth...
  68. pmc Cardiorespiratory fitness predicts changes in adiposity in overweight Hispanic boys
    Courtney E Byrd-Williams
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Obesity (Silver Spring) 16:1072-7. 2008
    ..These results suggest that cardiorespiratory fitness may be an important determinant of changes in adiposity in overweight Hispanic boys but not in girls...
  69. ncbi request reprint Aerobic fitness among Caucasian, African-American, and Latino youth
    Gabriel Q Shaibi
    Department of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, California, USA
    Ethn Dis 16:120-5. 2006
    ....
  70. ncbi request reprint Effects of resistance training on insulin sensitivity in overweight Latino adolescent males
    Gabriel Q Shaibi
    Department of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA 90033, USA
    Med Sci Sports Exerc 38:1208-15. 2006
    ..Therefore, we examined the effects of a 16-wk resistance training exercise intervention on insulin sensitivity in youth at high risk for developing type 2 diabetes...
  71. pmc Lower bone mineral content in hypertensive compared with normotensive overweight Latino children and adolescents
    Afrooz Afghani
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Am J Hypertens 20:190-6. 2007
    ..In adults, hypertension has been shown to be inversely correlated with bone mineral content (BMC); however, the association between blood pressure (BP) and BMC has not been studied in pediatrics...
  72. ncbi request reprint Bone, muscle, and fat: sex-related differences in prepubertal children
    Kiumars Arfai
    Department of Radiology, Childrens Hospital Los Angeles, 4650 Sunset Blvd, Mail Stop 81, Los Angeles, CA 90027, USA
    Radiology 224:338-44. 2002
    ..To determine whether there are sex-related differences in vertebral cross-sectional dimensions, in paraspinous muscle area, and in the amount of fat in the subcutaneous and visceral compartments of prepubertal boys and girls...
  73. pmc Persistence of the metabolic syndrome and its influence on carotid artery intima media thickness in overweight Latino children
    Claudia M Toledo-Corral
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089 9073, United States
    Atherosclerosis 206:594-8. 2009
    ..The objective of this study was to examine the influence of persistence of the metabolic syndrome (Mets) and its individual components over a 3-year period on carotid intima media thickness (CIMT) in overweight Latino children...
  74. ncbi request reprint Using genetic admixture to explain racial differences in insulin-related phenotypes
    Barbara A Gower
    Department of Nutrition Sciences, The University of Alabama at Birmingham, Birmingham, Alabama 35294 3360, USA
    Diabetes 52:1047-51. 2003
    ....
  75. ncbi request reprint Validity of body mass index compared with other body-composition screening indexes for the assessment of body fatness in children and adolescents
    Zuguo Mei
    Division of Nutrition and Physical Activity, Centers for Disease Control and Prevention, Atlanta, GA 30341 3724, USA
    Am J Clin Nutr 75:978-85. 2002
    ..Validation studies of height- and weight-based indexes of body fatness in children and adolescents have examined only small samples of school-age children...
  76. ncbi request reprint Contribution of insulin secretion and clearance to glucose-induced insulin concentration in african-american and caucasian children
    Barbara A Gower
    Department of Nutrition Sciences and Clinical Nutrition Research Center, University of Alabama at Birmingham 35294 3360, USA
    J Clin Endocrinol Metab 87:2218-24. 2002
    ..The insulin secretion data await verification that the kinetic parameters used apply to children and AA...
  77. ncbi request reprint Predicting total body fat from anthropometry in Latino children
    Terry T K Huang
    Energy Metabolism Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging and Gerald J and Dorothy R Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA
    Obes Res 11:1192-9. 2003
    ..To develop prediction equations for total body fat specific to Latino children, using demographic and anthropometric measures...
  78. ncbi request reprint Body-composition assessment via air-displacement plethysmography in adults and children: a review
    David A Fields
    Department of Internal Medicine, The Center for Human Nutrition, Washington University, St Louis, USA
    Am J Clin Nutr 75:453-67. 2002
    ..Wide intersubject variations between methods are partly attributed to technical precision and biological error but to a large extent remain unexplained. On the basis of this review, future research goals are suggested...
  79. ncbi request reprint Prevention of type 2 diabetes in young people: a theoretical perspective
    Terry T Huang
    Energy Metabolism Laboratory, Jean Mayer USDA Human Nutrition Research Center, Tufts University, Boston, USA
    Pediatr Diabetes 4:38-56. 2003
    ....
  80. ncbi request reprint Impaired glucose tolerance in obese children and adolescents
    Michael I Goran
    N Engl J Med 347:290-2; author reply 290-2. 2002
  81. ncbi request reprint Adiponectin is lower among African Americans and is independently related to insulin sensitivity in children and adolescents
    Nikki C Bush
    Department of Nutrition Sciences, University of Alabama at Birmingham, 429 Webb Building, 1675 University Blvd, Birmingham, AL 35294 3360, USA
    Diabetes 54:2772-8. 2005
    ..In addition, higher acute insulin response to glucose explained lower adiponectin among African-American children...
  82. ncbi request reprint Adiponectin independently predicts metabolic syndrome in overweight Latino youth
    Gabriel Q Shaibi
    College of Nursing and Healthcare Innovation, Arizona State University, Phoenix, AZ 85069, USA
    J Clin Endocrinol Metab 92:1809-13. 2007
    ..Adiponectin may be important in the pathogenesis of insulin resistance and the metabolic syndrome in youth...
  83. ncbi request reprint Predicting abdominal adipose tissue in overweight Latino youth
    Geoff D C Ball
    University of Alberta, Edmonton, AB, Canada
    Int J Pediatr Obes 1:210-6. 2006
    ....
  84. ncbi request reprint Exercise and insulin resistance in youth
    Gabriel Q Shaibi
    College of Nursing and Healthcare Innovation, Arizona State University, Phoenix, AZ 85004, USA
    Exerc Sport Sci Rev 36:5-11. 2008
    ..A growing body of literature suggests that exercise may ameliorate insulin resistance and thus potentially reduce the long-term diabetes risk in overweight youth...
  85. pmc Examining metabolic syndrome definitions in overweight Hispanic youth: a focus on insulin resistance
    Gabriel Q Shaibi
    College of Nursing and Healthcare Innovation, Arizona State University, Phoenix, Arizona, USA
    J Pediatr 152:171-6. 2008
    ..To examine the prevalence of the metabolic syndrome in overweight Hispanic youth according to 3 published pediatric definitions. Furthermore, the relationship of each definition to directly measured insulin resistance was examined...
  86. ncbi request reprint Frequency of hypoglycaemia during the intravenous glucose tolerance test in overweight children
    Martha L Cruz
    Department of Health Promotion, College of Health Sciences, University of Texas at El Paso, El Paso, TX 79902, USA
    Int J Pediatr Obes 2:122-5. 2007
    ..5% subjects). In addition, only 1.9% of subjects (n=4) had plasma glucose<60 mg/dl at any time during the FSIVGTT. The frequency of hypoglycaemia during the insulin modified FSIVGTT is very low in overweight Hispanic youth...
  87. pmc Associations among insulin, estrogen, and fat mass gain over the pubertal transition in African-American and European-American girls
    Krista Casazza
    Department of Nutrition Sciences, University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham, AL 35294 3360, USA
    J Clin Endocrinol Metab 93:2610-5. 2008
    ..Age at menarche (AgeM) is earlier in African-American (AA) than in European-American (EA) girls. Neither the physiological cause nor the health implications of this difference are known...
  88. ncbi request reprint Associations of adiposity with measured and self-reported academic performance in early adolescence
    Terry T K Huang
    Endocrinology, Nutrition, and Growth Branch, National Institute of Child Health and Human Development, 6100 Executive Boulevard, 4B11, Rockville, MD 20852, USA
    Obesity (Silver Spring) 14:1839-45. 2006
    ..To examine the associations of adiposity with measured and self-reported academic performance independently of demographics and physical activity among U.S. adolescents...
  89. ncbi request reprint Early ethnic difference in insulin-like growth factor-1 is associated with African genetic admixture
    Paul B Higgins
    Department of Nutrition Sciences and the Clinical Nutrition Research Center, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Pediatr Res 58:850-4. 2005
    ..01 for both). Thus, our data suggest that the greater IGF-1 of AA relative to EA children could have a genetic basis...
  90. ncbi request reprint Impaired glucose tolerance and bone mineral content in overweight latino children with a family history of type 2 diabetes
    Afrooz Afghani
    College of Health Sciences, Touro University International, 5665 Plaza Dr, Third Floor, Cypress, CA 90630, USA
    Diabetes Care 28:372-8. 2005
    ..We examined the hypothesis that bone mineral content (BMC) and bone mineral density (BMD) will be lower in children with impaired glucose tolerance (IGT) versus normal glucose tolerance (NGT)...
  91. ncbi request reprint Overweight as a risk factor in children: a focus on ethnicity
    Shawna D Nesbitt
    University of Texas Southwestern Medical Center at Dallas, Dallas 75390 8899, USA
    Ethn Dis 14:94-110. 2004
    ..This summary article reviews the data on cardiovascular risk factors and overweight in ethnic children and adolescents, and culminates in a practical algorithm for evaluating overweight children for cardiovascular risk...
  92. ncbi request reprint A festschrift for Roland L. Weinsier: nutrition scientist, educator, and clinician
    Douglas C Heimburger
    Department of Nutrition Sciences, Clinical Nutrition Research Center, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Obes Res 11:1246-62. 2003
    ..Sadly, Roland Weinsier died on November 27, 2002. He will be missed and remembered by many as a revered and beloved teacher, mentor, healer, and scholar...
  93. doi request reprint Cardiorespiratory fitness is strongly related to the metabolic syndrome in adolescents: response to Janssen and Cramp
    Gabriel Q Shaibi
    Diabetes Care 31:e8; author reply e9. 2008
  94. ncbi request reprint Developmental trajectories of overweight during childhood: role of early life factors
    Chaoyang Li
    University of Kansas Medical Center, Kansas City, Kansas, USA
    Obesity (Silver Spring) 15:760-71. 2007
    ..Our goal was to identify developmental trajectories of overweight in children and to assess early life influences on these trajectories...

Research Grants27

  1. INTRA-ABDOMINAL FAT AND RISK OF DISEASE IN ADOLESCENTS
    Michael Goran; Fiscal Year: 2005
    ....
  2. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2006
    ..The findings will be valuable for the design of treatment and prevention interventions in this high-risk population. ..
  3. INTRA-ABDOMINAL FAT AND RISK OF DISEASE IN ADOLESCENTS
    Michael Goran; Fiscal Year: 2006
    ....
  4. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2007
    ..The findings will be valuable for the design of treatment and prevention interventions in this high-risk population. ..
  5. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2006
    ..The findings will be valuable for the design of treatment and prevention interventions in this high-risk population. ..
  6. INTRA-ABDOMINAL FAT AND RISK OF DISEASE IN ADOLESCENTS
    Michael Goran; Fiscal Year: 2007
    ....
  7. USC Center for Transdisciplinary Research on Energetics*
    Michael Goran; Fiscal Year: 2007
    ..Our overall vision is based on the concept that preventing obesity and promoting health in children will improve long-term cancer control in the population. ..
  8. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2009
    ....
  9. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2004
    ..abstract_text> ..
  10. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2005
    ..The findings will be valuable for the design of treatment and prevention interventions in this high-risk population. ..
  11. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2004
    ..abstract_text> ..
  12. INTRA-ABDOMINAL FAT AND RISK OF DISEASE IN ADOLESCENTS
    Michael Goran; Fiscal Year: 2000
    ....
  13. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2001
    ..abstract_text> ..
  14. INTRA-ABDOMINAL FAT AND RISK OF DISEASE IN ADOLESCENTS
    Michael Goran; Fiscal Year: 2001
    ....
  15. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2002
    ..abstract_text> ..
  16. INTRA-ABDOMINAL FAT AND RISK OF DISEASE IN ADOLESCENTS
    Michael Goran; Fiscal Year: 2002
    ..abstract_text> ..
  17. INTRA-ABDOMINAL FAT AND RISK OF DISEASE IN ADOLESCENTS
    Michael Goran; Fiscal Year: 2003
    ..abstract_text> ..
  18. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2003
    ..abstract_text> ..
  19. INTRA-ABDOMINAL FAT AND RISK OF DISEASE IN ADOLESCENTS
    Michael Goran; Fiscal Year: 2004
    ..abstract_text> ..
  20. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    Michael Goran; Fiscal Year: 2004
    ..abstract_text> ..
  21. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    MICHAEL ISAAC GORAN; Fiscal Year: 2010
    ....