Wayne K Goodman

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi request reprint Treatment of generalized anxiety disorder with escitalopram: pooled results from double-blind, placebo-controlled trials
    Wayne K Goodman
    Department of Psychiatry, University of Florida, PO Box 100256, Gainesville, FL 32610, USA
    J Affect Disord 87:161-7. 2005
  2. ncbi request reprint Risk of adverse behavioral effects with pediatric use of antidepressants
    Wayne K Goodman
    Department of Psychiatry, University of Florida College of Medicine, McKnight Brain Institute, Room L4 100, P O Box 100256, Gainesville, FL 32610 0256, USA
    Psychopharmacology (Berl) 191:87-96. 2007
  3. ncbi request reprint Obsessive-compulsive disorder in Tourette syndrome
    Wayne K Goodman
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Child Neurol 21:704-14. 2006
  4. ncbi request reprint Selecting pharmacotherapy for generalized anxiety disorder
    Wayne K Goodman
    Department of Psychiatry, University of Florida College of Medicine, Gainesville, FL 32611, USA
    J Clin Psychiatry 65:8-13. 2004
  5. doi request reprint Insight in pediatric obsessive-compulsive disorder: associations with clinical presentation
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL, USA
    Psychiatry Res 160:212-20. 2008
  6. ncbi request reprint Florida Obsessive-Compulsive Inventory: development, reliability, and validity
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Clin Psychol 63:851-9. 2007
  7. ncbi request reprint Clinical features associated with treatment-resistant pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Compr Psychiatry 49:35-42. 2008
  8. ncbi request reprint Clinical features of children and adolescents with obsessive-compulsive disorder and hoarding symptoms
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Compr Psychiatry 48:313-8. 2007
  9. pmc Sleep-related problems in pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Anxiety Disord 22:877-85. 2008
  10. ncbi request reprint Quality of life in youth with Tourette's syndrome and chronic tic disorder
    Eric A Storch
    Department of Psychiatry and Pediatrics, University of Florida, Gainesville, FL 32610, USA
    J Clin Child Adolesc Psychol 36:217-27. 2007

Research Grants

Detail Information

Publications71

  1. ncbi request reprint Treatment of generalized anxiety disorder with escitalopram: pooled results from double-blind, placebo-controlled trials
    Wayne K Goodman
    Department of Psychiatry, University of Florida, PO Box 100256, Gainesville, FL 32610, USA
    J Affect Disord 87:161-7. 2005
    ..Escitalopram 10 mg/day is an effective and well-tolerated antidepressant. Three randomized controlled trials recently evaluated the safety and efficacy of escitalopram in the treatment of generalized anxiety disorder (GAD)...
  2. ncbi request reprint Risk of adverse behavioral effects with pediatric use of antidepressants
    Wayne K Goodman
    Department of Psychiatry, University of Florida College of Medicine, McKnight Brain Institute, Room L4 100, P O Box 100256, Gainesville, FL 32610 0256, USA
    Psychopharmacology (Berl) 191:87-96. 2007
    ....
  3. ncbi request reprint Obsessive-compulsive disorder in Tourette syndrome
    Wayne K Goodman
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Child Neurol 21:704-14. 2006
    ....
  4. ncbi request reprint Selecting pharmacotherapy for generalized anxiety disorder
    Wayne K Goodman
    Department of Psychiatry, University of Florida College of Medicine, Gainesville, FL 32611, USA
    J Clin Psychiatry 65:8-13. 2004
    ....
  5. doi request reprint Insight in pediatric obsessive-compulsive disorder: associations with clinical presentation
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL, USA
    Psychiatry Res 160:212-20. 2008
    ..These findings suggest that OCD with poor insight may represent a distinct clinical feature that may require more intensive and multimodal treatment approaches...
  6. ncbi request reprint Florida Obsessive-Compulsive Inventory: development, reliability, and validity
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Clin Psychol 63:851-9. 2007
    ..A strength of the FOCI is that it offers a quick evaluation of both presence and severity of OCD symptoms. An important limitation is that the FOCI does not assess the severity of individual symptoms...
  7. ncbi request reprint Clinical features associated with treatment-resistant pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Compr Psychiatry 49:35-42. 2008
    ..The objective of the study was to identify clinical and sociodemographic characteristics that may differentiate youth with obsessive-compulsive disorder (OCD) who are resistant to treatment vs those who have a favorable response...
  8. ncbi request reprint Clinical features of children and adolescents with obsessive-compulsive disorder and hoarding symptoms
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Compr Psychiatry 48:313-8. 2007
    ..This study was conducted to examine whether pediatric patients with obsessive-compulsive disorder (OCD) and hoarding symptoms differed in terms of clinical characteristics from pediatric OCD patients without hoarding symptoms...
  9. pmc Sleep-related problems in pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Anxiety Disord 22:877-85. 2008
    ..These results suggest that SRPs are relatively common in youth with OCD, are associated with symptom severity, and warrant attention during assessment and treatment...
  10. ncbi request reprint Quality of life in youth with Tourette's syndrome and chronic tic disorder
    Eric A Storch
    Department of Psychiatry and Pediatrics, University of Florida, Gainesville, FL 32610, USA
    J Clin Child Adolesc Psychol 36:217-27. 2007
    ....
  11. ncbi request reprint Family accommodation in pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Clin Child Adolesc Psychol 36:207-16. 2007
    ..Family accommodation mediated the relation between symptom severity and parent-rated functional impairment...
  12. ncbi request reprint Peer victimization in children with obsessive-compulsive disorder: relations with symptoms of psychopathology
    Eric A Storch
    Department of Psychiatry and Department of Pediatrics, University of Florida, Box 100234, Gainesville, FL 32610, USA
    J Clin Child Adolesc Psychol 35:446-55. 2006
    ..Recognition of the magnitude of the problem and contribution problematic peer relations may play in comorbid psychological conditions is important for clinicians who see children with OCD...
  13. ncbi request reprint D-cycloserine does not enhance exposure-response prevention therapy in obsessive-compulsive disorder
    Eric A Storch
    Departments of Psychiatry, University of Florida, Florida 32610, USA
    Int Clin Psychopharmacol 22:230-7. 2007
    ..As this study is the first to explore this question and a number of methodological issues must be considered when interpreting the findings, the conclusions that may be drawn from our results are limited...
  14. doi request reprint Impact of comorbidity on cognitive-behavioral therapy response in pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Am Acad Child Adolesc Psychiatry 47:583-92. 2008
    ..To examine the impact of psychiatric comorbidity on cognitive-behavioral therapy response in children and adolescents with obsessive-compulsive disorder...
  15. ncbi request reprint Reliability and validity of the Yale Global Tic Severity Scale
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, 32610, USA
    Psychol Assess 17:486-91. 2005
    ..07-.20), and child ratings of depression (r = .02-.26) and anxiety (r = -.06 -.28). Findings suggest that the YGTSS is a reliable and valid instrument for the assessment of pediatric TS...
  16. ncbi request reprint Family-based cognitive-behavioral therapy for pediatric obsessive-compulsive disorder: comparison of intensive and weekly approaches
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Am Acad Child Adolesc Psychiatry 46:469-78. 2007
    ..To examine the relative efficacy of intensive versus weekly cognitive-behavioral therapy (CBT) for children and adolescents with obsessive-compulsive disorder (OCD)...
  17. ncbi request reprint The children's Yale-Brown obsessive-compulsive scale: psychometric properties of child- and parent-report formats
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA
    J Anxiety Disord 20:1055-70. 2006
    ..Exploratory factor analyses identified a two-factor structure in both measures comprised of disturbance and severity factors. This study provides preliminary support for the use of child- and parent-report versions of the CY-BOCS...
  18. ncbi request reprint Sequential cognitive-behavioral therapy for children with obsessive-compulsive disorder with an inadequate medication response: a case series of five patients
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, Florida 326110, USA
    Depress Anxiety 24:375-81. 2007
    ..Although a number of limitations of this preliminary report exist, this study provides preliminary support for the utility of an intensive intervention for youth with OCD who have had an inadequate response and/or adverse side effects...
  19. ncbi request reprint Factor analytic study of the Children's Yale-Brown Obsessive-Compulsive Scale
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesvile, FL 32610, USA
    J Clin Child Adolesc Psychol 34:312-9. 2005
    ..These findings suggest that the CY-BOCS Total Score may represent an inaccurate assessment of symptom severity and supports the use of the revised Severity and Disturbance factors in assessing illness severity...
  20. ncbi request reprint Further psychometric properties of the Tourette's Disorder Scale-Parent Rated version (TODS-PR)
    Eric A Storch
    Department of Psychiatry, University of Florida, Box 100234, Gainesville, FL 32610, USA
    Child Psychiatry Hum Dev 35:107-20. 2004
    ..The TODS-PR Total Score and factors showed good convergent validity with other measures of symptomatology and impairment. These findings suggest that the TODS-PR is a reliable and valid parent-rating scale for assessing TD symptoms...
  21. doi request reprint Convergent and discriminant validity of the Children's Yale-Brown Obsessive Compulsive Scale-Symptom Checklist
    Jason Gallant
    Department of Educational Psychology, University of Florida, Gainesville, FL 32610, United States
    J Anxiety Disord 22:1369-76. 2008
    ..These results provide initial psychometric support for the CY-BOCS-SC and support its use as a clinical and research instrument for assessing presence of a range of obsessive and compulsive symptoms in youth with OCD...
  22. ncbi request reprint Obsessive-compulsive disorder in youth with and without a chronic tic disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, Florida 32610, USA
    Depress Anxiety 25:761-7. 2008
    ..Implications of these findings on clinical presentation and treatment efficacy are highlighted...
  23. ncbi request reprint Clinical predictors of early fluoxetine treatment response in obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, Florida 32610, USA
    Depress Anxiety 23:429-33. 2006
    ..Furthermore, findings suggest early predictors of patients with certain characteristics who may ultimately need adjunctive care to facilitate response...
  24. ncbi request reprint Effect of comorbid tics on a clinically meaningful response to 8-week open-label trial of fluoxetine in obsessive compulsive disorder
    David S Husted
    Department of Psychiatry, University of Florida College of Medicine, P O Box 100256, Gainesville, FL 32610 0256, USA
    J Psychiatr Res 41:332-7. 2007
    ..Limitations include the relatively low number of tic subjects and the open-label nature of the study. Additional data are needed on how comorbid tics may affect SRI treatment response in OCD...
  25. doi request reprint Deep brain stimulation for intractable obsessive compulsive disorder: pilot study using a blinded, staggered-onset design
    Wayne K Goodman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
    Biol Psychiatry 67:535-42. 2010
    ..Prior promising results have been reported with deep brain stimulation (DBS) of the anterior limb of the internal capsule in cases with severe obsessive compulsive disorder (OCD) who had exhausted conventional therapies...
  26. pmc Cognitive behavioral therapy plus motivational interviewing improves outcome for pediatric obsessive-compulsive disorder: a preliminary study
    Lisa J Merlo
    Department of Psychiatry, University of Florida, Gainesville, Florida, USA
    Cogn Behav Ther 39:24-7. 2010
    ....
  27. doi request reprint Associations between miscellaneous symptoms and symptom dimensions in adults with obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610 USA
    Anxiety Stress Coping 21:199-212. 2008
    ..g., hierarchy development)...
  28. ncbi request reprint A measure of functional impairment in youth with Tourette's syndrome
    Eric A Storch
    Department of Psychiatry, University of Florida, Box 100234, Gainesville, FL 32610, USA
    J Pediatr Psychol 32:950-9. 2007
    ..The current study was undertaken to examine both tic-related impairment and impairment from other psychological problems in 59 youth (mean age 11.4 years, 69% male) with TS...
  29. pmc Deep brain stimulation in the internal capsule and nucleus accumbens region: responses observed during active and sham programming
    Michael S Okun
    Department of Neurology, Movement Disorders Center, University of Florida, PO Box 100236, Gainesville, FL 32610, USA
    J Neurol Neurosurg Psychiatry 78:310-4. 2007
    ..The stimulation-induced benefits and side effects can be reversibly and blindly applied to a variety of locations in this region...
  30. ncbi request reprint Associations between miscellaneous symptoms and symptom dimensions: an examination of pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Behav Res Ther 45:2593-603. 2007
    ..g., understanding which miscellaneous symptoms relate to certain dimensions) and treatment implications (e.g., hierarchy development)...
  31. doi request reprint A pilot study of vagus nerve stimulation (VNS) for treatment-resistant anxiety disorders
    Mark S George
    Department of Psychiatry, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Brain Stimul 1:112-21. 2008
    ....
  32. doi request reprint Cognitive-behavioral therapy for obsessive-compulsive disorder: a non-randomized comparison of intensive and weekly approaches
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Anxiety Disord 22:1146-58. 2008
    ..Since many people with OCD do not have access to trained CBT providers, intensive treatment may be a viable option in such cases...
  33. ncbi request reprint Reliability and validity of the Child Behavior Checklist Obsessive-Compulsive Scale
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, 32610, USA
    J Anxiety Disord 20:473-85. 2006
    ..Suggestions for cutoff scores are provided using results from ROC analyses. Overall, these findings suggest that the OCS-R is a reliable and valid instrument for the assessment of pediatric OCD...
  34. ncbi request reprint Cognitive-behavioral therapy for PANDAS-related obsessive-compulsive disorder: findings from a preliminary waitlist controlled open trial
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Am Acad Child Adolesc Psychiatry 45:1171-8. 2006
    ....
  35. pmc Psychometric properties of the Treatment-Emergent Activation and Suicidality Assessment Profile (TEASAP) in youth with OCD
    Regina Bussing
    Department of Psychiatry, Pediatrics and Clinical and Health Psychology, University of Florida, Box 100234, UFHSC, Gainesville, FL 32610 0234, USA
    Psychiatry Res 205:253-61. 2013
    ..Findings indicate that the TEASAP has acceptable psychometric properties in a clinical sample of youth with OCD and merits further study in larger samples for additional refinement of its measurement approaches...
  36. doi request reprint A trial of scheduled deep brain stimulation for Tourette syndrome: moving away from continuous deep brain stimulation paradigms
    Michael S Okun
    Department of Neurology, University of Florida Center for Movement Disorders and Neurorestoration, Gainesville, FL, USA
    JAMA Neurol 70:85-94. 2013
    ..To collect the information necessary to design the methods and outcome variables for a larger trial of scheduled deep brain stimulation (DBS) for Tourette syndrome...
  37. doi request reprint Right and left dorsolateral pre-frontal rTMS treatment of refractory depression: a randomized, sham-controlled trial
    William J Triggs
    Neurology Service and the Brain Rehabilitation Research Center of Excellence, Department of Veterans Affairs Medical Center, Gainesville, FL 32608 1197, USA
    Psychiatry Res 178:467-74. 2010
    ..2007), albeit not statistically significant. These results suggest that somatosensory stimuli that repeatedly engage the left hemisphere may be important to the achievement of therapeutic effect...
  38. ncbi request reprint A double-blind, placebo-controlled trial of olanzapine addition in fluoxetine-refractory obsessive-compulsive disorder
    Nathan A Shapira
    Department of Psychiatry, College of Medicine, University of Florida, Gainesville, Florida 32610 0256, USA
    Biol Psychiatry 55:553-5. 2004
    ..One of the few combination approaches to the treatment of obsessive-compulsive disorder (OCD) with encouraging support is the addition of an antipsychotic to a serotonin reuptake inhibitor...
  39. doi request reprint SSRI adverse events: how to monitor and manage
    Tanya K Murphy
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Int Rev Psychiatry 20:203-8. 2008
    ..With diligence to appropriate prescribing and monitoring, the benefits of therapy outweigh the potential of treatment related risk...
  40. ncbi request reprint Factor-analytic study of the Yale Global Tic Severity Scale
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Psychiatry Res 149:231-7. 2007
    ..These findings support the use of the original scoring structure in assessing pediatric tic severity...
  41. ncbi request reprint Further psychometric examination of the Tourette's Disorder Scales
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Child Psychiatry Hum Dev 38:89-98. 2007
    ..Excellent inter-rater agreement and convergent and divergent validity was found. These results provide further psychometric support for the TODS-PR and TODS-CR...
  42. ncbi request reprint Psychometric evaluation of the Children's Yale-Brown Obsessive-Compulsive Scale
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Psychiatry Res 129:91-8. 2004
    ..Findings suggest that the CY-BOCS is a reliable and valid instrument for the assessment of childhood obsessions and compulsions...
  43. ncbi request reprint Hope and coping in family members of patients with obsessive-compulsive disorder
    Gary R Geffken
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Anxiety Disord 20:614-29. 2006
    ..Coping mediated the relationship between hope and depressive symptoms. Given the importance of family members in treatment, clinical implications of these findings are discussed...
  44. ncbi request reprint Yale-Brown Obsessive Compulsive Scale: the dimensional structure revisited
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, Florida 32610, USA
    Depress Anxiety 22:28-35. 2005
    ..Reliability and convergent validity of these factors were generally satisfactory, although divergent validity was not entirely supported. Implications of these findings on scoring the Y-BOCS are discussed...
  45. ncbi request reprint Assessment of pediatric obsessive-compulsive disorder: a critical review of current methodology
    Lisa J Merlo
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Child Psychiatry Hum Dev 36:195-214. 2005
    ..Finally, a critical review is offered of major trends in the assessment of pediatric OCD (e.g., diagnostic interviews, self-report and parent-report measures, and clinician-administered inventories)...
  46. ncbi request reprint Relationship of movements and behaviors to Group A Streptococcus infections in elementary school children
    Tanya K Murphy
    Department of Psychiatry, College of Medicine, Gainesville, Florida 32610, USA
    Biol Psychiatry 61:279-84. 2007
    ..Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus (PANDAS) research is based on the hypothesis that infections trigger changes in behavior and movement in children...
  47. doi request reprint Concurrent validity of the Yale-Brown Obsessive-Compulsive Scale-Symptom Checklist
    Michael L Sulkowski
    University of Florida, FL, USA
    J Clin Psychol 64:1338-51. 2008
    ..54) with the STAI-T. These findings reveal some of the strengths and weaknesses of these two OCD instruments, and the results provide guidance for selecting scales that are suitable for measuring OCD symptoms...
  48. ncbi request reprint Long-term habituation of the smile response with deep brain stimulation
    Utaka S Springer
    Clinical and Health Psychology, McKnight Brain Institute, University of Florida, Gainsville, Florida 32610 0165, USA
    Neurocase 12:191-6. 2006
    ..The smiles could not be elicited even with long washout periods. These findings imply potential long-term habituation and changes in the neural chemistry (possibly neuroplasticity) induced by chronic DBS...
  49. ncbi request reprint Cognitive-behavioral therapy for obsessive-compulsive disorder: review of treatment techniques
    Gary R Geffken
    Department of Psychiatry, University of Florida Health Science Center, Gainesville, FL 32610, USA
    J Psychosoc Nurs Ment Health Serv 42:44-51. 2004
    ..This article provides a review of CBT for OCD. Issues related to treatment delivery and assessment are presented and highlighted by an individual example...
  50. ncbi request reprint Lessons learned in deep brain stimulation for movement and neuropsychiatric disorders
    Frank M Skidmore
    Department of Neurology, McKnight Brain Institute, University of Florida College of Medicine in Gainesville, 32610, USA
    CNS Spectr 11:521-36. 2006
    ..Also discussed are the emerging targets, what is known about the cognitive sequelae of DBS, and what has been learned about the complications and therapeutic failures...
  51. ncbi request reprint Immunology of obsessive-compulsive disorder
    Tanya K Murphy
    Department of Psychiatry, University of Florida School of Medicine, Gainesville, FL 32610, USA
    Psychiatr Clin North Am 29:445-69. 2006
    ..The assimilation of these study results should allow for elucidation of the immune system's role in the onset and maintenance of OCD...
  52. ncbi request reprint Cognitive-behavioral treatment for obsessive-compulsive disorder in an elderly male with concurrent medical constraints
    Adam Hirsh
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Am J Geriatr Psychiatry 14:380-1. 2006
  53. ncbi request reprint The neurocircuitry of obsessive-compulsive disorder and disgust
    David S Husted
    Department of Psychiatry, University of Florida College of Medicine, P O Box 100256 Gainesville, FL 32610 0256, USA
    Prog Neuropsychopharmacol Biol Psychiatry 30:389-99. 2006
    ..This review focuses on describing what is known to date concerning the neurocircuitry of disgust, and its relevance to the apparent neurocircuitry of OCD...
  54. ncbi request reprint Recognition and treatment of obsessive-compulsive disorder
    Wayne K Goodman
    Department of Psychiatry, University of Florida College of Medicine, Gainesville, USA
    J Clin Psychiatry 68:e30. 2007
    ..Neurosurgery, such as deep brain stimulation, has also been shown to be effective in select patients with debilitating and refractory OCD...
  55. ncbi request reprint Topiramate attenuates self-injurious behaviour in Prader-Willi Syndrome
    Nathan A Shapira
    Department of Psychiatry, Evelyn F and William L McKnight Brain Institute of the University of Florida, Gainsville 32610 0256, USA
    Int J Neuropsychopharmacol 5:141-5. 2002
    ....
  56. ncbi request reprint Cerebral blood flow changes in depressed patients after treatment with repetitive transcranial magnetic stimulation: evidence of individual variability
    Stephen E Nadeau
    Geriatric Research, Education and Clinical Center, Malcolm Randall Department of Veteran Affairs Medical Center, Gainseville, Florida 32608 1197, USA
    Neuropsychiatry Neuropsychol Behav Neurol 15:159-75. 2002
    ..To elucidate the neural mechanisms of depression...
  57. doi request reprint Deep brain stimulation for intractable psychiatric disorders
    Wayne K Goodman
    Department of Psychiatry, Friedman Brain Institute of the Mount Sinai School of Medicine, New York, New York 10029, USA
    Annu Rev Med 63:511-24. 2012
    ..g., hypomania). Further research is needed to test the efficacy and safety of DBS in psychiatric disorders, compare targets, and identify predictors of response...
  58. ncbi request reprint Effects of topiramate in adults with Prader-Willi syndrome
    Nathan A Shapira
    College of Medicine, University of Florida, Gainesville 32610, USA
    Am J Ment Retard 109:301-9. 2004
    ..e., skin-picking) that is characteristic of this syndrome. Potential benefits of topiramate for self-injury should be evaluated further in controlled trials...
  59. ncbi request reprint Deep brain stimulation for refractory obsessive-compulsive disorder
    Adam Burdick
    University of Florida, Department of Neurosurgery, PO Box 100265, Gainesville, FL, 32610, USA
    Front Biosci (Landmark Ed) 14:1880-90. 2009
    ..The promising early results of DBS for OCD are summarized, including a discussion of current targets and programming issues. Finally, the ethical implications of the procedure are briefly discussed...
  60. ncbi request reprint What's in a "smile?" Intra-operative observations of contralateral smiles induced by deep brain stimulation
    Michael S Okun
    Movement Disorders Center, University of Florida, Department of Neurology, McKnight Brain Institute, Gaineville, FL 32610, USA
    Neurocase 10:271-9. 2004
    ..To describe smiling and euphoria induced by deep brain stimulation (DBS)...
  61. ncbi request reprint A double-blind, placebo-controlled study of the efficacy and safety of controlled-release fluvoxamine in patients with obsessive-compulsive disorder
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Psychiatry 64:640-7. 2003
    ....
  62. ncbi request reprint Brain activation by disgust-inducing pictures in obsessive-compulsive disorder
    Nathan A Shapira
    Department of Psychiatry, College of Medicine, University of Florida, Gainesville, Florida, USA
    Biol Psychiatry 54:751-6. 2003
    ..There is growing interest in the role of disgust in the pathogenesis of obsessive-compulsive disorder (OCD)...
  63. ncbi request reprint Detecting pediatric autoimmune neuropsychiatric disorders associated with streptococcus in children with obsessive-compulsive disorder and tics
    Tanya K Murphy
    Department of Psychiatry, University of Florida, Gainesville, Florida 32610 0256, USA
    Biol Psychiatry 55:61-8. 2004
    ....
  64. doi request reprint Where does obsessive-compulsive disorder belong in DSM-V?
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, Florida, USA
    Depress Anxiety 25:336-47. 2008
    ..We conclude that a reclassification of OCD into a separate OCSD spectrum is premature and not supported by the currently available data...
  65. ncbi request reprint Suicidality as a possible side effect of antidepressant treatment
    Larry Culpepper
    Department of Family Medicine, Boston Medical Center, MA, USA
    J Clin Psychiatry 65:742-9. 2004
  66. ncbi request reprint A qualitative analysis of nonresponse: management of treatment-refractory obsessive-compulsive disorder
    Stefano Pallanti
    Department of Psychiatry, University of Florence, Italy
    J Clin Psychiatry 65:6-10. 2004
    ..More results are needed before the effectiveness of the nonpharmacologic treatments for OCD can be determined...
  67. ncbi request reprint Symptom stability in adult obsessive-compulsive disorder: data from a naturalistic two-year follow-up study
    David Mataix-Cols
    Department of Psychiatry, Imperial College School of Medicine, London, UK
    Am J Psychiatry 159:263-8. 2002
    ..This study systematically investigated the temporal stability of individual symptoms and symptom dimensions of OCD in adult patients who were followed prospectively for 2 years...
  68. ncbi request reprint Escitalopram for the treatment of GAD: efficacy across different subgroups and outcomes
    Dan J Stein
    University of Stellenbosch, Department of Psychiatry, P O Box 19063, Tygerberg, 7505, South Africa
    Ann Clin Psychiatry 17:71-5. 2005
    ..In this study, we determined whether the selective serotonin reuptake inhibitor escitalopram, was effective across different subgroups and outcomes (anxious symptoms, depressive symptoms, and quality of life)...
  69. ncbi request reprint Three-year outcomes in deep brain stimulation for highly resistant obsessive-compulsive disorder
    Benjamin D Greenberg
    Department of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital and Rhode Island Hospital, Providence, RI 02906, USA
    Neuropsychopharmacology 31:2384-93. 2006
    ..This open study found promising long-term effects of DBS in highly treatment-resistant OCD...
  70. doi request reprint Avoiding deep brain stimulation failures in Tourette syndrome
    Michael S Okun
    J Neurol Neurosurg Psychiatry 79:111-2. 2008
  71. ncbi request reprint Tourette syndrome: diagnosis, strategies, therapies, pathogenesis, and future research directions
    Lori L Olson
    College of Medicine, University of Missouri Columbia, Columbia, MO, USA
    J Child Neurol 21:630-41. 2006

Research Grants2

  1. Pilot Study of DBS for Treatment-Refractory OCD
    Herbert Ward; Fiscal Year: 2006
    ..If shown effective, DBS might replace ablative neurosurgery, but should still be considered the intervention of last resort in the most profoundly ill and intractable cases of OCD. ..
  2. SSRI-Induced Activation Syndrome In Pediatric OCD
    Tanya Murphy; Fiscal Year: 2007
    ..Development of an activation syndrome measurement tool will be useful in future large-scale clinical trials that test the relationship between activation syndrome and suicidality. ..