Francisco Gonzalez Scarano

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Microglia as mediators of inflammatory and degenerative diseases
    F Gonzalez-Scarano
    Department of Neurology, University of Pennsylvania Medical Center, Philadelphia 19104 6146, USA
    Annu Rev Neurosci 22:219-40. 1999
  2. ncbi request reprint The neuropathogenesis of AIDS
    Francisco González-Scarano
    Department of Neurology, 3 West Gates, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Philadelphia 19104 4283, USA
    Nat Rev Immunol 5:69-81. 2005
  3. ncbi request reprint Microarray analysis of activated mixed glial (microglia) and monocyte-derived macrophage gene expression
    Andrew V Albright
    Department of Neurology, University of Pennsylvania, 255 Clinical Research Building, 415 Curie Boulevard, Philadelphia, PA 19104 6146, USA
    J Neuroimmunol 157:27-38. 2004
  4. pmc Annexin 2: a novel human immunodeficiency virus type 1 Gag binding protein involved in replication in monocyte-derived macrophages
    Elena V Ryzhova
    Department of Neurology and Microbiology, University of Pennsylvania, 3 W Gates, 3400 Spruce Street, Philadelphia, Pennsylvania 19104 4283, USA
    J Virol 80:2694-704. 2006

Research Grants

  1. ROLE OF MICROGLIA IN HIV/DEMENTIA
    Francisco Gonzalez Scarano; Fiscal Year: 2005
  2. Genetics of Simian Immunodeficiency Virus Encephalopathy
    Francisco Gonzalez Scarano; Fiscal Year: 2007
  3. SHORT-TERM TRAINING FOR MINORITY STUDENTS
    Francisco Gonzalez Scarano; Fiscal Year: 2007
  4. TRAINING IN NEUROVIROLOGY
    Francisco Gonzalez Scarano; Fiscal Year: 2007
  5. ROLE OF MICROGLIA IN HIV/DEMENTIA
    Francisco Gonzalez Scarano; Fiscal Year: 2004
  6. MICROGLIA AND HIV DEMENTIA
    Francisco Gonzalez Scarano; Fiscal Year: 1999
  7. G PROTEIN COUPLED RECEPTORS AND HIV DEMENTIA
    Francisco Gonzalez Scarano; Fiscal Year: 2001
  8. Characterization of the La Crosse Virus glycoprotein fusion peptide
    Francisco Gonzalez Scarano; Fiscal Year: 2009

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Microglia as mediators of inflammatory and degenerative diseases
    F Gonzalez-Scarano
    Department of Neurology, University of Pennsylvania Medical Center, Philadelphia 19104 6146, USA
    Annu Rev Neurosci 22:219-40. 1999
    ..In this review we discuss the role of microglia in three diseases in which their activity is at least partially deleterious: HIV, multiple sclerosis, and Alzheimer's disease...
  2. ncbi request reprint The neuropathogenesis of AIDS
    Francisco González-Scarano
    Department of Neurology, 3 West Gates, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Philadelphia 19104 4283, USA
    Nat Rev Immunol 5:69-81. 2005
    ..Here, we discuss the studies that are being carried out to determine the respective contributions of infection, and monocyte and macrophage activation, to disease progression...
  3. ncbi request reprint Microarray analysis of activated mixed glial (microglia) and monocyte-derived macrophage gene expression
    Andrew V Albright
    Department of Neurology, University of Pennsylvania, 255 Clinical Research Building, 415 Curie Boulevard, Philadelphia, PA 19104 6146, USA
    J Neuroimmunol 157:27-38. 2004
    ....
  4. pmc Annexin 2: a novel human immunodeficiency virus type 1 Gag binding protein involved in replication in monocyte-derived macrophages
    Elena V Ryzhova
    Department of Neurology and Microbiology, University of Pennsylvania, 3 W Gates, 3400 Spruce Street, Philadelphia, Pennsylvania 19104 4283, USA
    J Virol 80:2694-704. 2006
    ..Cumulatively, our data suggest that Anx2 is essential for the proper assembly of HIV in MDM...

Research Grants25

  1. ROLE OF MICROGLIA IN HIV/DEMENTIA
    Francisco Gonzalez Scarano; Fiscal Year: 2005
    ..These results will expand our understanding of lentiviral infection of macrophages, and potentially provide an additional target for therapeutic intervention in HIV and HAD. ..
  2. Genetics of Simian Immunodeficiency Virus Encephalopathy
    Francisco Gonzalez Scarano; Fiscal Year: 2007
    ..These experiments will help clarify the role of genetic sequestration in the development of SIV encephalitis, and by extension, in its human counterpart. ..
  3. SHORT-TERM TRAINING FOR MINORITY STUDENTS
    Francisco Gonzalez Scarano; Fiscal Year: 2007
    ....
  4. TRAINING IN NEUROVIROLOGY
    Francisco Gonzalez Scarano; Fiscal Year: 2007
    ..Core services available within the University of Pennsylvania include protein sequencing, peptide and oligonucleotide synthesis, transgenic and 'knock-out' technology, microarray analysis, automated DNA sequencing and many others. ..
  5. ROLE OF MICROGLIA IN HIV/DEMENTIA
    Francisco Gonzalez Scarano; Fiscal Year: 2004
    ..The results from these experiments will strengthen knowledge about the interactions between HIV-1 and microglial cells. ..
  6. MICROGLIA AND HIV DEMENTIA
    Francisco Gonzalez Scarano; Fiscal Year: 1999
    ..The results of these studies should help delineate the rational treatment of HIVD. ..
  7. G PROTEIN COUPLED RECEPTORS AND HIV DEMENTIA
    Francisco Gonzalez Scarano; Fiscal Year: 2001
    ..The results of these studies will further our understanding of the pathophysiology of HIV dementia. ..
  8. Characterization of the La Crosse Virus glycoprotein fusion peptide
    Francisco Gonzalez Scarano; Fiscal Year: 2009
    ..abstract_text> ..