Genomes and Genes
Benjamin A Goldstein
Affiliation: University of California
- An application of Random Forests to a genome-wide association dataset: methodological considerations & new findingsBenjamin A Goldstein
Division of Biostatistics, School of Public Health, University of California, Berkeley, CA, USA
BMC Genet 11:49. 2010..One such approach is the Random Forests (RF) algorithm. The use of RF for SNP discovery related to human disease has grown in recent years; however, most work has focused on small datasets or simulation studies which are limited...
- Variation within DNA repair pathway genes and risk of multiple sclerosisFarren B S Briggs
University of California, Berkeley, 94720, USA
Am J Epidemiol 172:217-24. 2010..Although other candidate genes examined here warrant further follow-up studies, collectively, these results derived from a well-powered study do not support a strong role for common variation within DNA repair pathway genes in MS...
- Breast cancer risk factors differ between Asian and white women with BRCA1/2 mutationsMonique A de Bruin
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
Fam Cancer 11:429-39. 2012..Further investigation of racial differences in BRCA1/2 mutation epidemiology could inform targeted cancer risk-reduction strategies...
- Trends in relative mortality between Hispanic and non-Hispanic whites initiating dialysis: a retrospective study of the US Renal Data SystemCristina M Arce
Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA
Am J Kidney Dis 62:312-21. 2013..It is unknown whether this association differs by age, has changed over time, or is due to differential access to kidney transplantation...
- Donor predictors of allograft use and recipient outcomes after heart transplantationKiran K Khush
Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA
Circ Heart Fail 6:300-9. 2013..We sought to identify donor predictors of allograft nonuse, and to determine whether these predictors are in fact associated with adverse recipient post-transplant outcomes...