F D Goldman

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. pmc Defective expression of p56lck in an infant with severe combined immunodeficiency
    F D Goldman
    Department of Pediatrics, University of Iowa, Iowa City, Iowa 52242, USA
    J Clin Invest 102:421-9. 1998
  2. ncbi request reprint Hydroxychloroquine inhibits calcium signals in T cells: a new mechanism to explain its immunomodulatory properties
    F D Goldman
    Department of Pediatrics, University of Iowa, Iowa City, IA 52242, USA
    Blood 95:3460-6. 2000
  3. ncbi request reprint Aberrant T-cell antigen receptor-mediated responses in autoimmune lymphoproliferative syndrome
    Frederick D Goldman
    Department of Pediatrics, University of Iowa Hospitals and Clinics and Veterans Affairs Medical Center, Iowa City, 52242, USA
    Clin Immunol 104:31-9. 2002
  4. ncbi request reprint Chronic granulomatous disease presenting with disseminated intracranial aspergillosis
    Abdul Alsultan
    Department of Pediatrics, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
    Pediatr Blood Cancer 47:107-10. 2006
  5. pmc Characterization of primitive hematopoietic cells from patients with dyskeratosis congenita
    Frederick D Goldman
    Department of Pediatrics, Division of Hematology Oncology, University of Iowa Children s Hospital, Iowa City 52242, USA
    Blood 111:4523-31. 2008
  6. pmc Change in erythropoietin pharmacokinetics following hematopoietic transplantation
    J A Widness
    Department of Pediatrics, The College of Medicine, The University of Iowa, Iowa City, Iowa, USA
    Clin Pharmacol Ther 81:873-9. 2007
  7. ncbi request reprint Intact T cell responses in ataxia telangiectasia
    Farzana Pashankar
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    Clin Immunol 120:156-62. 2006
  8. pmc Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts
    Erik R Westin
    Interdisciplinary Program in Genetics, University of Iowa, Iowa City, IA 52242, USA
    Aging Cell 6:383-94. 2007
  9. ncbi request reprint gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes
    Sandrina Kinet
    Institut de Genetique Moleculaire de Montpellier, Centre National de Recherche Scientifique CNRS UMR 5535 IFR 22, Montpellier, France
    Blood 100:2546-53. 2002

Collaborators

Detail Information

Publications9

  1. pmc Defective expression of p56lck in an infant with severe combined immunodeficiency
    F D Goldman
    Department of Pediatrics, University of Iowa, Iowa City, Iowa 52242, USA
    J Clin Invest 102:421-9. 1998
    ..These data suggest that a deficiency in p56lck expression can produce a SCID phenotype in humans...
  2. ncbi request reprint Hydroxychloroquine inhibits calcium signals in T cells: a new mechanism to explain its immunomodulatory properties
    F D Goldman
    Department of Pediatrics, University of Iowa, Iowa City, IA 52242, USA
    Blood 95:3460-6. 2000
    ..Together, these findings suggest that disruption of TCR-crosslinking-dependent calcium signaling provides an additional mechanism to explain the immunomodulatory properties of HCQ...
  3. ncbi request reprint Aberrant T-cell antigen receptor-mediated responses in autoimmune lymphoproliferative syndrome
    Frederick D Goldman
    Department of Pediatrics, University of Iowa Hospitals and Clinics and Veterans Affairs Medical Center, Iowa City, 52242, USA
    Clin Immunol 104:31-9. 2002
    ..As DN T cells were essentially anergic, the clinical manifestations of autoimmunity are more likely to be a consequence of aberrant cytokine secretion within the CD4(+) T-cell subpopulation...
  4. ncbi request reprint Chronic granulomatous disease presenting with disseminated intracranial aspergillosis
    Abdul Alsultan
    Department of Pediatrics, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
    Pediatr Blood Cancer 47:107-10. 2006
    ..Whereas, optimal pharmacologic therapy is still unknown for CNS aspergillosis, voriconazole may have an advantage due to its ability to cross the blood brain barrier and excellent oral absorption and bioavailability...
  5. pmc Characterization of primitive hematopoietic cells from patients with dyskeratosis congenita
    Frederick D Goldman
    Department of Pediatrics, Division of Hematology Oncology, University of Iowa Children s Hospital, Iowa City 52242, USA
    Blood 111:4523-31. 2008
    ....
  6. pmc Change in erythropoietin pharmacokinetics following hematopoietic transplantation
    J A Widness
    Department of Pediatrics, The College of Medicine, The University of Iowa, Iowa City, Iowa, USA
    Clin Pharmacol Ther 81:873-9. 2007
    ..The association of EPO elimination with decreased bone marrow activity in patients undergoing transplantation conclusively establishes the bone marrow as a key determinant of EPO elimination in humans...
  7. ncbi request reprint Intact T cell responses in ataxia telangiectasia
    Farzana Pashankar
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    Clin Immunol 120:156-62. 2006
    ..This helps to explain the paucity of opportunistic infections encountered, unlike that encountered in other primary immunodeficiencies...
  8. pmc Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts
    Erik R Westin
    Interdisciplinary Program in Genetics, University of Iowa, Iowa City, IA 52242, USA
    Aging Cell 6:383-94. 2007
    ..Similar strategies may be useful for ameliorating the detrimental effects of telomere shortening in AD DC and other diseases associated with telomerase or telomere defects...
  9. ncbi request reprint gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes
    Sandrina Kinet
    Institut de Genetique Moleculaire de Montpellier, Centre National de Recherche Scientifique CNRS UMR 5535 IFR 22, Montpellier, France
    Blood 100:2546-53. 2002
    ..These studies reveal a mechanism via which gp120 may differentially modulate the fate of activated and quiescent T cells in vivo...