Genomes and Genes




Affiliation: University of California
Country: USA


  1. Walker M, Hayes E, Saint D, Adaikan G, Abraham S, Goldin A, et al. Pharmacological and toxicological activity of RSD921, a novel sodium channel blocker. Biomed Pharmacother. 2018;106:510-522 pubmed publisher
    ..RSD921 primarily blocks sodium currents, and possesses antiarrhythmic and local anaesthetic activity. ..
  2. Makinson C, Dutt K, Lin F, Papale L, Shankar A, Barela A, et al. An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior. Exp Neurol. 2016;275 Pt 1:46-58 pubmed publisher
    ..These results expand the phenotypes associated with disruption of the Scn8a gene and demonstrate that an Scn8a mutation can both confer seizure protection and increase seizure susceptibility. ..