Neil A Goldenberg

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc Outcomes of mentored, grant-funded fellowship training in haemostasis /thrombosis: findings from a nested case-control survey study
    N A Goldenberg
    Section of Hematology Oncology Bone Marrow Transplantation and the Mountain States Regional Hemophilia and Thrombosis Center, Department of Pediatrics, University of Colorado, Aurora, CO 80045 0507, USA
    Haemophilia 18:326-31. 2012
  2. pmc Validation of upper extremity post-thrombotic syndrome outcome measurement in children
    Neil A Goldenberg
    Department of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation and the Mountain States Hemophilia and Thrombosis Center, University of Colorado Denver and The Children s Hospital, Aurora, CO, USA
    J Pediatr 157:852-5. 2010
  3. pmc Post-thrombotic syndrome in children: a systematic review of frequency of occurrence, validity of outcome measures, and prognostic factors
    Neil A Goldenberg
    Department of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation and the Mountain States Regional Hemophilia and Thrombosis Center, Univ of Colorado Denver and The Children s Hospital, Aurora, CO 80045, USA
    Haematologica 95:1952-9. 2010
  4. doi request reprint The "parallel-cohort RCT": Novel design aspects and application in the Kids-DOTT trial of pediatric venous thromboembolism
    Neil A Goldenberg
    Dept of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation and Mountain States Regional Hemophilia and Thrombosis Center, Univ of Colorado Denver and The Children s Hospital, Aurora, CO, USA
    Contemp Clin Trials 31:131-3. 2010
  5. pmc Percutaneous mechanical and pharmacomechanical thrombolysis for occlusive deep vein thrombosis of the proximal limb in adolescent subjects: findings from an institution-based prospective inception cohort study of pediatric venous thromboembolism
    Neil A Goldenberg
    Department of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation and Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado, Aurora, Colorado 80045, USA
    J Vasc Interv Radiol 22:121-32. 2011
  6. doi request reprint Cardiac findings and long-term thromboembolic outcomes following pulmonary embolism in children: a combined retrospective-prospective inception cohort study
    Hayley S Hancock
    Department of Pediatrics, University of Colorado School of Medicine, Children s Hospital Colorado, Aurora, Colorado 80045, USA
    Cardiol Young 23:344-52. 2013
  7. doi request reprint Biomarkers of hypercoagulability and inflammation in childhood-onset arterial ischemic stroke
    Timothy J Bernard
    Department of Pediatrics, Section of Child Neurology, Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado Denver and The Children s Hospital, Aurora, CO 80045 0507, USA
    J Pediatr 156:651-6. 2010
  8. pmc The roles of anatomic factors, thrombophilia, and antithrombotic therapies in childhood-onset arterial ischemic stroke
    Timothy J Bernard
    Department of Pediatrics, Section of Child Neurology, Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado Denver and The Children s Hospital, Aurora, Colorado, USA
    Thromb Res 127:6-12. 2011
  9. doi request reprint Acute prognostic factors for post-thrombotic syndrome in children with limb DVT: a bi-institutional cohort study
    Courtney A Lyle
    Department of Pediatrics, Division of Hematology Oncology, University of California San Diego and Rady Children s Hospital, San Diego, CA, USA
    Thromb Res 131:37-41. 2013
  10. doi request reprint Anticoagulation in childhood-onset arterial ischemic stroke with non-moyamoya arteriopathy: findings from the Colorado and German (COAG) collaboration
    Timothy J Bernard
    Pediatric Neurology, B155, The Children s Hospital, Denver, 13123 East 16th Avenue, Aurora, CO 80045, USA
    Stroke 40:2869-71. 2009

Collaborators

Detail Information

Publications42

  1. pmc Outcomes of mentored, grant-funded fellowship training in haemostasis /thrombosis: findings from a nested case-control survey study
    N A Goldenberg
    Section of Hematology Oncology Bone Marrow Transplantation and the Mountain States Regional Hemophilia and Thrombosis Center, Department of Pediatrics, University of Colorado, Aurora, CO 80045 0507, USA
    Haemophilia 18:326-31. 2012
    ....
  2. pmc Validation of upper extremity post-thrombotic syndrome outcome measurement in children
    Neil A Goldenberg
    Department of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation and the Mountain States Hemophilia and Thrombosis Center, University of Colorado Denver and The Children s Hospital, Aurora, CO, USA
    J Pediatr 157:852-5. 2010
    ..Interrater reliability in an independent validation cohort (n = 38) of children with or without upper extremity deep venous thrombosis was 97%-100%...
  3. pmc Post-thrombotic syndrome in children: a systematic review of frequency of occurrence, validity of outcome measures, and prognostic factors
    Neil A Goldenberg
    Department of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation and the Mountain States Regional Hemophilia and Thrombosis Center, Univ of Colorado Denver and The Children s Hospital, Aurora, CO 80045, USA
    Haematologica 95:1952-9. 2010
    ..This systematic review was conducted to critically evaluate pediatric evidence on frequency of occurrence, validity of outcome measures, and prognostic indicators of post-thrombotic syndrome...
  4. doi request reprint The "parallel-cohort RCT": Novel design aspects and application in the Kids-DOTT trial of pediatric venous thromboembolism
    Neil A Goldenberg
    Dept of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation and Mountain States Regional Hemophilia and Thrombosis Center, Univ of Colorado Denver and The Children s Hospital, Aurora, CO, USA
    Contemp Clin Trials 31:131-3. 2010
    ....
  5. pmc Percutaneous mechanical and pharmacomechanical thrombolysis for occlusive deep vein thrombosis of the proximal limb in adolescent subjects: findings from an institution-based prospective inception cohort study of pediatric venous thromboembolism
    Neil A Goldenberg
    Department of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation and Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado, Aurora, Colorado 80045, USA
    J Vasc Interv Radiol 22:121-32. 2011
    ..The present report is an evaluation of experience with adjunctive percutaneous mechanical thrombolysis (PMT) and/or percutaneous pharmacomechanical thrombolysis (PPMT) in such patients...
  6. doi request reprint Cardiac findings and long-term thromboembolic outcomes following pulmonary embolism in children: a combined retrospective-prospective inception cohort study
    Hayley S Hancock
    Department of Pediatrics, University of Colorado School of Medicine, Children s Hospital Colorado, Aurora, Colorado 80045, USA
    Cardiol Young 23:344-52. 2013
    ..Right ventricular dysfunction was rare in follow-up. These data indicate that acute heart strain is common, but chronic cardiac dysfunction is rare, following aggressive management of acute pulmonary embolism in children...
  7. doi request reprint Biomarkers of hypercoagulability and inflammation in childhood-onset arterial ischemic stroke
    Timothy J Bernard
    Department of Pediatrics, Section of Child Neurology, Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado Denver and The Children s Hospital, Aurora, CO 80045 0507, USA
    J Pediatr 156:651-6. 2010
    ....
  8. pmc The roles of anatomic factors, thrombophilia, and antithrombotic therapies in childhood-onset arterial ischemic stroke
    Timothy J Bernard
    Department of Pediatrics, Section of Child Neurology, Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado Denver and The Children s Hospital, Aurora, Colorado, USA
    Thromb Res 127:6-12. 2011
    ..Consensus-based guidelines have been developed, but future research must emphasize identification of additional prognostic factors and the initiation of cooperative randomized controlled clinical trials...
  9. doi request reprint Acute prognostic factors for post-thrombotic syndrome in children with limb DVT: a bi-institutional cohort study
    Courtney A Lyle
    Department of Pediatrics, Division of Hematology Oncology, University of California San Diego and Rady Children s Hospital, San Diego, CA, USA
    Thromb Res 131:37-41. 2013
    ....
  10. doi request reprint Anticoagulation in childhood-onset arterial ischemic stroke with non-moyamoya arteriopathy: findings from the Colorado and German (COAG) collaboration
    Timothy J Bernard
    Pediatric Neurology, B155, The Children s Hospital, Denver, 13123 East 16th Avenue, Aurora, CO 80045, USA
    Stroke 40:2869-71. 2009
    ..We sought to investigate the safety of extended anticoagulation in childhood arterial ischemic stroke with nonmoyamoya arteriopathy, for which the risk of recurrent stroke is high...
  11. doi request reprint The institution-based prospective inception cohort study: design, implementation, and quality assurance in pediatric thrombosis and stroke research
    Timothy J Bernard
    Department of Pediatrics, Section of Child Neurology, University of Colorado, Aurora, USA
    Semin Thromb Hemost 39:10-4. 2013
    ..Following multicenter validation, its findings can inform the design and execution of much-needed randomized controlled clinical trials...
  12. pmc A thrombolytic regimen for high-risk deep venous thrombosis may substantially reduce the risk of postthrombotic syndrome in children
    Neil A Goldenberg
    University of Colorado at Denver and Health Sciences Center, Department of Pediatrics, Section of Hematology, Center for Cancer and Blood Disorders, The Children s Hospital, Denver, CO 80045, USA
    Blood 110:45-53. 2007
    ..These findings suggest that the use of a thrombolysis regimen may safely and substantially reduce the risk of PTS in children with occlusive lower-extremity acute DVT, providing the basis for a future clinical trial...
  13. pmc Towards a consensus-based classification of childhood arterial ischemic stroke
    Timothy J Bernard
    Sections of Child Neurology and Hemophilia and Thrombosis Center, Department of Pediatrics, School of Public Health, University of Colorado, Aurora, CO, USA
    Stroke 43:371-7. 2012
    ..In contrast, current classification and nomenclature in childhood AIS are often overlapping or contradictory. Our purpose was to develop a comprehensive consensus-based classification system for childhood AIS...
  14. pmc Childhood arterial ischemic stroke: a review of etiologies, antithrombotic treatments, prognostic factors, and priorities for future research
    Courtney A Lyle
    Division of Hematology Oncology, Department of Pediatrics, University of California, San Diego, California, USA
    Semin Thromb Hemost 37:786-93. 2011
    ..We also identify priorities for future research...
  15. doi request reprint Monitoring hypercoagulability and hypofibrinolysis following acute venous Thromboembolism in children: application of the CloFAL assay in a prospective inception cohort study
    Christopher Bombardier
    Department of Pediatrics, University of Colorado School of Medicine and Children s Hospital Colorado, Aurora, CO 80045, USA
    Thromb Res 130:343-9. 2012
    ..These findings indicate the utility of the CloFAL assay in monitoring plasma coagulative and fibrinolytic capacities in children with VTE. Studies of its potential role in outcome prediction are ongoing...
  16. doi request reprint Simultaneous thrombin and plasmin generation capacities in normal and abnormal states of coagulation and fibrinolysis in children and adults
    Mindy L Simpson
    Rush University Medical Center, Department of Pediatrics, Section of Hematology Oncology, Chicago, IL 60612, USA
    Thromb Res 127:317-23. 2011
    ..Plasma coagulative and fibrinolytic potentials in normal children and adults, and in representative pathologically altered hemostatic states, were evaluated via simultaneous assessment of thrombin and plasmin generation...
  17. doi request reprint Antithrombotic treatments, outcomes, and prognostic factors in acute childhood-onset arterial ischaemic stroke: a multicentre, observational, cohort study
    Neil A Goldenberg
    Department of Pediatrics, University of Colorado Denver, Children s Hospital, and Mountain States Regional Hemophilia and Thrombosis Center, Aurora, CO, USA
    Lancet Neurol 8:1120-7. 2009
    ..We aimed to describe frequencies and predictors of acute treatments and early outcomes in the International Pediatric Stroke Study (IPSS), a large international series of childhood AIS...
  18. ncbi request reprint Lemierre's and Lemierre's-like syndromes in children: survival and thromboembolic outcomes
    Neil A Goldenberg
    Department of Pediatrics, University of Colorado Health Sciences Center, The Children s Hospital, Denver, Colorado, USA
    Pediatrics 116:e543-8. 2005
    ....
  19. doi request reprint Antithrombotic therapies: anticoagulation and thrombolysis
    Ruchika Goel
    Division of Hematology and Oncology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA
    Pediatr Clin North Am 60:1463-74. 2013
    ....
  20. pmc Overweight and obesity are increased in childhood-onset cerebrovascular disease
    Virginia Pearson
    School of Medicine, University of Colorado Denver, Aurora, CO 80045, USA
    J Child Neurol 28:517-9. 2013
    ..In conclusion, the prevalence of overweight/obese was significantly increased in cerebral sinovenous thrombosis patients as compared to both national and local controls. Results should be evaluated in a larger multi-institutional cohort...
  21. doi request reprint Treatment, survival, and thromboembolic outcomes of thrombotic storm in children
    Marilyn J Manco-Johnson
    Department of Pediatrics, The Children s Hospital, University of Colorado School of Medicine, Aurora, CO 80045, USA
    J Pediatr 161:682-8.e1. 2012
    ..To describe the course and management of thrombotic storm in 8 children...
  22. ncbi request reprint Elevated plasma factor VIII and D-dimer levels as predictors of poor outcomes of thrombosis in children
    Neil A Goldenberg
    Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Health Sciences Center and The Children s Hospital, 1056 E 19th Ave, B 115, Denver, CO 80218, USA
    N Engl J Med 351:1081-8. 2004
    ....
  23. doi request reprint High prevalence of thrombophilic traits in children with family history of thromboembolism
    Meghan J Calhoon
    Section of Hematology, Oncology, and Bone Marrow Transplantation, Department of Pediatrics, and the Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado Denver and The Children s Hospital, Aurora, CO 80045, USA
    J Pediatr 157:485-9. 2010
    ....
  24. doi request reprint Venous thromboembolism in children
    Neil A Goldenberg
    Mountain States Regional Hemophilia and Thrombosis Center, P O Box 6507, Mail Stop F 416, Aurora, CO 80045 0507, USA
    Pediatr Clin North Am 55:305-22, vii. 2008
    ..Prognostic indicators and long-term outcomes are considered, with emphasis on available evidence underlying current knowledge and key questions for further investigation...
  25. doi request reprint Pediatric arterial ischemic stroke
    Timothy J Bernard
    Mountain States Regional Hemophilia and Thrombosis Center, P O Box 6507, Mail Stop F 416, Aurora, CO 80045 0507, USA
    Pediatr Clin North Am 55:323-38, viii. 2008
    ..Long-term outcomes of recurrent AIS and neuromotor, speech, cognitive, and behavioral deficits are considered. Emphasis is on evidence underlying current knowledge and key questions for further investigation...
  26. doi request reprint The methylenetetrahydrofolate reductase polymorphism (MTHFR c.677C>T) and elevated plasma homocysteine levels in a U.S. pediatric population with incident thromboembolism
    Emily Joachim
    Department of Pediatrics and the Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado and Children s Hospital Colorado, Aurora, CO, USA Department of Medicine and the Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado and Children s Hospital Colorado, Aurora, CO, USA
    Thromb Res 132:170-4. 2013
    ..The objectives of this study were to determine the prevalences of elevated tHcy and MTHFR variant in a pediatric population with VTE or arterial ischemic stroke (AIS), and to determine associations with thrombus outcomes...
  27. doi request reprint Institution-based prospective inception cohort studies in neonatal rare disease research
    Jennifer Armstrong-Wells
    Department of Pediatrics, Section of Neurology, University of Colorado, Aurora CO, USA
    Semin Fetal Neonatal Med 16:355-8. 2011
    ....
  28. doi request reprint Treatment of childhood arterial ischemic stroke
    Timothy J Bernard
    Department of Pediatrics, University of Colorado, The Children s Hospital, Denver, CO 80045, USA
    Ann Neurol 63:679-96. 2008
    ..Ongoing and future multicenter cohort study efforts, and ultimately devoted pediatric clinical trials, will be essential to establish comprehensive evidence-based guidelines for the treatment of childhood AIS...
  29. doi request reprint Anti-Xa stability of diluted dalteparin for pediatric use
    Neil A Goldenberg
    Mountain States Regional Hemophilia and Thrombosis Center and Coagulation Research Laboratory, University of Colorado and the Children s Hospital, Aurora, CO 80045, USA
    Ann Pharmacother 42:511-5. 2008
    ..However, dalteparin is commonly available in the US in a concentrated form that requires dilution for accurate administration in infants and young children...
  30. doi request reprint Pediatric arterial ischemic stroke
    Timothy J Bernard
    Mountain States Regional Hemophilia and Thrombosis Center, Aurora, CO 80045 0507, USA
    Hematol Oncol Clin North Am 24:167-80. 2010
    ..Long-term outcomes of recurrent AIS and neuromotor, speech, cognitive, and behavioral deficits are considered. Emphasis is on evidence underlying current knowledge and key questions for further investigation...
  31. pmc Craniocervical arterial dissection in children: diagnosis and treatment
    Nicholas V Stence
    University of Colorado Hemophilia and Thrombosis Center, P O Box 6507, Aurora, CO, 80045 0507, USA
    Curr Treat Options Neurol 13:636-48. 2011
    ..We also educate our patients with CCAD about the signs and symptoms of recurrence and the importance of emergent evaluation...
  32. doi request reprint Venous thromboembolism in children
    Neil A Goldenberg
    Mountain States Regional Hemophilia and Thrombosis Center, Aurora, CO 80045 0507, USA
    Hematol Oncol Clin North Am 24:151-66. 2010
    ..Prognostic indicators and long-term outcomes are considered, with emphasis on available evidence underlying current knowledge and key questions for further investigation...
  33. doi request reprint L-Carnitine plus cilostazol versus cilostazol alone for the treatment of claudication in patients with peripheral artery disease: a multicenter, randomized, double-blind, placebo-controlled trial
    Neil A Goldenberg
    Department of Medicine, Division of Hematology, University of Colorado School of Medicine, Aurora, CO 80045, USA
    Vasc Med 17:145-54. 2012
    ..145 for cilostazol/placebo (p = 0.048). QOL measures were also improved in the cilostazol/l-carnitine group. These findings support larger trials of l-carnitine in combination with cilostazol in the treatment of IC...
  34. pmc Risk factors for in-hospital venous thromboembolism in children: a case-control study employing diagnostic validation
    Brian R Branchford
    Department of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation, University of Colorado Denver and Children s Hospital Colorado, Aurora, CO 80045 0507, USA
    Haematologica 97:509-15. 2012
    ..The objective of this study is to determine risk factors for the development of in-hospital venous thromboembolism in children...
  35. ncbi request reprint Long-term outcomes of venous thrombosis in children
    Neil A Goldenberg
    Section of Hematology, Oncology, and Bone Marrow Transplantation, Department of Pediatrics, University of Colorado Health Sciences Center The Children s Hospital, Denver, CO 80045 0507, USA
    Curr Opin Hematol 12:370-6. 2005
    ....
  36. ncbi request reprint A new global assay of coagulation and fibrinolysis
    Neil A Goldenberg
    Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Health Sciences Center The Children s Hospital, Denver, CO, USA
    Thromb Res 116:345-56. 2005
    ..In this research, a global assay that measures both coagulation and fibrinolytic capacities was developed and investigated...
  37. ncbi request reprint Brief communication: duration of platelet dysfunction after a 7-day course of Ibuprofen
    Neil A Goldenberg
    Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado Health Sciences Center, Aurora, Colorado 80045 0507, USA
    Ann Intern Med 142:506-9. 2005
    ..Despite a paucity of evidence, clinicians routinely advise that patients discontinue using nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, at least 1 week before most surgical procedures...
  38. doi request reprint Athletic participation in severe hemophilia: bleeding and joint outcomes in children on prophylaxis
    Cassie Ross
    Department of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation and Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado Denver and Children s Hospital, Aurora, Colorado 80045 0507, USA
    Pediatrics 124:1267-72. 2009
    ....
  39. doi request reprint Varied opinions on thrombolysis for venous thromboembolism in infants and children: findings from a survey of pediatric hematology-oncology specialists
    Donald L Yee
    Department of Pediatrics, Hematology Oncology Section, Baylor College of Medicine, Houston, Texas 77030, USA
    Pediatr Blood Cancer 53:960-6. 2009
    ..Recent guidelines discourage routine use of thrombolytic agents for treatment of venous thromboembolism (VTE) in pediatric patients, but actual practice patterns are unknown...
  40. pmc Improving academic leadership and oversight in large industry-sponsored clinical trials: the ARO-CRO model
    Neil A Goldenberg
    Department of Medicine, Section of Hematology Oncology, University of Colorado, Aurora, CO, USA
    Blood 117:2089-92. 2011
    ..Although numerous models can be entertained, the ARO-CRO model is uniquely structured to meet the demand for greater assurance of integrity in clinical trials and the needs of each stakeholder in the process...
  41. doi request reprint Tacrolimus as an alternative to cyclosporine in the maintenance phase of immunosuppressive therapy for severe aplastic anemia in children
    Abdulrahman Alsultan
    Center for Cancer and Blood Disorders, The Children s Hospital, University of Colorado Denver, Aurora, Colorado 80045, USA
    Pediatr Blood Cancer 52:626-30. 2009
    ....
  42. ncbi request reprint Pediatric hemostasis and use of plasma components
    Neil A Goldenberg
    Section of Hematology, Oncology, and Bone Marrow Transplantation, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO, USA
    Best Pract Res Clin Haematol 19:143-55. 2006
    ..This chapter reviews evidence to support the use of plasma and plasma derivatives for pediatric patients...