N A Goldenberg

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi Elevated plasma factor VIII and D-dimer levels as predictors of poor outcomes of thrombosis in children
    Neil A Goldenberg
    Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Health Sciences Center and The Children s Hospital, 1056 E 19th Ave, B 115, Denver, CO 80218, USA
    N Engl J Med 351:1081-8. 2004
  2. doi Venous thromboembolism in children
    Neil A Goldenberg
    Mountain States Regional Hemophilia and Thrombosis Center, P O Box 6507, Mail Stop F 416, Aurora, CO 80045 0507, USA
    Pediatr Clin North Am 55:305-22, vii. 2008
  3. doi Anti-Xa stability of diluted dalteparin for pediatric use
    Neil A Goldenberg
    Mountain States Regional Hemophilia and Thrombosis Center and Coagulation Research Laboratory, University of Colorado and the Children s Hospital, Aurora, CO 80045, USA
    Ann Pharmacother 42:511-5. 2008
  4. ncbi Influence of factor IX on overall plasma coagulability and fibrinolytic potential as measured by global assay: monitoring in haemophilia B
    N A Goldenberg
    Center for Cancer and Blood Disorders, Department of Pediatrics, University of Colorado at Denver and Health Sciences Center The Children s Hospital, Aurora, CO, USA
    Haemophilia 14:68-77. 2008
  5. ncbi Influence of factor VIII on overall coagulability and fibrinolytic potential of haemophilic plasma as measured by global assay: monitoring in haemophilia A
    N A Goldenberg
    Section of Hematology, Oncology, and Bone Marrow Transplantation, Department of Pediatrics, University of Colorado at Denver, Denver, USA
    Haemophilia 12:605-14. 2006
  6. ncbi Lemierre's and Lemierre's-like syndromes in children: survival and thromboembolic outcomes
    Neil A Goldenberg
    Department of Pediatrics, University of Colorado Health Sciences Center, The Children s Hospital, Denver, Colorado, USA
    Pediatrics 116:e543-8. 2005
  7. ncbi Long-term outcomes of venous thrombosis in children
    Neil A Goldenberg
    Section of Hematology, Oncology, and Bone Marrow Transplantation, Department of Pediatrics, University of Colorado Health Sciences Center The Children s Hospital, Denver, CO 80045 0507, USA
    Curr Opin Hematol 12:370-6. 2005
  8. ncbi A new global assay of coagulation and fibrinolysis
    Neil A Goldenberg
    Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Health Sciences Center The Children s Hospital, Denver, CO, USA
    Thromb Res 116:345-56. 2005
  9. ncbi Brief communication: duration of platelet dysfunction after a 7-day course of Ibuprofen
    Neil A Goldenberg
    Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado Health Sciences Center, Aurora, Colorado 80045 0507, USA
    Ann Intern Med 142:506-9. 2005
  10. ncbi Successful treatment of severe aplastic anemia in children using standardized immunosuppressive therapy with antithymocyte globulin and cyclosporine A
    Neil A Goldenberg
    Division of Hematology, Oncology, and BMT, Department of Pediatrics, UCHSC The Children s Hospital, Denver, Colorado 80128, USA
    Pediatr Blood Cancer 43:718-22. 2004

Research Grants

  1. Clinical Investigation in Pediatric Thrombosis
    Neil Goldenberg; Fiscal Year: 2007

Detail Information

Publications28

  1. ncbi Elevated plasma factor VIII and D-dimer levels as predictors of poor outcomes of thrombosis in children
    Neil A Goldenberg
    Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Health Sciences Center and The Children s Hospital, 1056 E 19th Ave, B 115, Denver, CO 80218, USA
    N Engl J Med 351:1081-8. 2004
    ....
  2. doi Venous thromboembolism in children
    Neil A Goldenberg
    Mountain States Regional Hemophilia and Thrombosis Center, P O Box 6507, Mail Stop F 416, Aurora, CO 80045 0507, USA
    Pediatr Clin North Am 55:305-22, vii. 2008
    ..Prognostic indicators and long-term outcomes are considered, with emphasis on available evidence underlying current knowledge and key questions for further investigation...
  3. doi Anti-Xa stability of diluted dalteparin for pediatric use
    Neil A Goldenberg
    Mountain States Regional Hemophilia and Thrombosis Center and Coagulation Research Laboratory, University of Colorado and the Children s Hospital, Aurora, CO 80045, USA
    Ann Pharmacother 42:511-5. 2008
    ..However, dalteparin is commonly available in the US in a concentrated form that requires dilution for accurate administration in infants and young children...
  4. ncbi Influence of factor IX on overall plasma coagulability and fibrinolytic potential as measured by global assay: monitoring in haemophilia B
    N A Goldenberg
    Center for Cancer and Blood Disorders, Department of Pediatrics, University of Colorado at Denver and Health Sciences Center The Children s Hospital, Aurora, CO, USA
    Haemophilia 14:68-77. 2008
    ....
  5. ncbi Influence of factor VIII on overall coagulability and fibrinolytic potential of haemophilic plasma as measured by global assay: monitoring in haemophilia A
    N A Goldenberg
    Section of Hematology, Oncology, and Bone Marrow Transplantation, Department of Pediatrics, University of Colorado at Denver, Denver, USA
    Haemophilia 12:605-14. 2006
    ..These findings indicate that the CloFAL assay may be useful as an adjunctive test to FVIII activity measurements in the therapeutic monitoring of haemophilia A...
  6. ncbi Lemierre's and Lemierre's-like syndromes in children: survival and thromboembolic outcomes
    Neil A Goldenberg
    Department of Pediatrics, University of Colorado Health Sciences Center, The Children s Hospital, Denver, Colorado, USA
    Pediatrics 116:e543-8. 2005
    ....
  7. ncbi Long-term outcomes of venous thrombosis in children
    Neil A Goldenberg
    Section of Hematology, Oncology, and Bone Marrow Transplantation, Department of Pediatrics, University of Colorado Health Sciences Center The Children s Hospital, Denver, CO 80045 0507, USA
    Curr Opin Hematol 12:370-6. 2005
    ....
  8. ncbi A new global assay of coagulation and fibrinolysis
    Neil A Goldenberg
    Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Health Sciences Center The Children s Hospital, Denver, CO, USA
    Thromb Res 116:345-56. 2005
    ..In this research, a global assay that measures both coagulation and fibrinolytic capacities was developed and investigated...
  9. ncbi Brief communication: duration of platelet dysfunction after a 7-day course of Ibuprofen
    Neil A Goldenberg
    Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado Health Sciences Center, Aurora, Colorado 80045 0507, USA
    Ann Intern Med 142:506-9. 2005
    ..Despite a paucity of evidence, clinicians routinely advise that patients discontinue using nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, at least 1 week before most surgical procedures...
  10. ncbi Successful treatment of severe aplastic anemia in children using standardized immunosuppressive therapy with antithymocyte globulin and cyclosporine A
    Neil A Goldenberg
    Division of Hematology, Oncology, and BMT, Department of Pediatrics, UCHSC The Children s Hospital, Denver, Colorado 80128, USA
    Pediatr Blood Cancer 43:718-22. 2004
    ..Given the heterogeneity of published data in US children, we sought to evaluate outcomes of a standardized immunosuppressive therapy (IST) regimen for severe aplastic anemia (SAA) at The Children's Hospital (Denver, CO)...
  11. doi Biomarkers of hypercoagulability and inflammation in childhood-onset arterial ischemic stroke
    Timothy J Bernard
    Department of Pediatrics, Section of Child Neurology, Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado Denver and The Children s Hospital, Aurora, CO 80045 0507, USA
    J Pediatr 156:651-6. 2010
    ....
  12. ncbi Use of global assays to understand clinical phenotype in congenital factor VII deficiency
    L A Greene
    Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA
    Haemophilia 19:765-72. 2013
    ..These preliminary findings suggest a novel potential link between a hyperfibrinolytic state in bleeding severity and congenital FVII deficiency, an observation that should be further explored...
  13. ncbi Maternal risk factors for term neonatal seizures: population-based study in Colorado, 1989-2003
    Deborah A Hall
    Department of Neurology, University of Colorado at Denver and Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    J Child Neurol 21:795-8. 2006
    ..Maternal diabetic vasculopathy can also be a contributing factor...
  14. ncbi Anticoagulation in childhood-onset arterial ischemic stroke with non-moyamoya arteriopathy: findings from the Colorado and German (COAG) collaboration
    Timothy J Bernard
    Pediatric Neurology, B155, The Children s Hospital, Denver, 13123 East 16th Avenue, Aurora, CO 80045, USA
    Stroke 40:2869-71. 2009
    ..We sought to investigate the safety of extended anticoagulation in childhood arterial ischemic stroke with nonmoyamoya arteriopathy, for which the risk of recurrent stroke is high...
  15. doi Pediatric arterial ischemic stroke
    Timothy J Bernard
    Mountain States Regional Hemophilia and Thrombosis Center, Aurora, CO 80045 0507, USA
    Hematol Oncol Clin North Am 24:167-80. 2010
    ..Long-term outcomes of recurrent AIS and neuromotor, speech, cognitive, and behavioral deficits are considered. Emphasis is on evidence underlying current knowledge and key questions for further investigation...
  16. doi Treatment of childhood arterial ischemic stroke
    Timothy J Bernard
    Department of Pediatrics, University of Colorado, The Children s Hospital, Denver, CO 80045, USA
    Ann Neurol 63:679-96. 2008
    ..Ongoing and future multicenter cohort study efforts, and ultimately devoted pediatric clinical trials, will be essential to establish comprehensive evidence-based guidelines for the treatment of childhood AIS...
  17. doi Pediatric arterial ischemic stroke
    Timothy J Bernard
    Mountain States Regional Hemophilia and Thrombosis Center, P O Box 6507, Mail Stop F 416, Aurora, CO 80045 0507, USA
    Pediatr Clin North Am 55:323-38, viii. 2008
    ..Long-term outcomes of recurrent AIS and neuromotor, speech, cognitive, and behavioral deficits are considered. Emphasis is on evidence underlying current knowledge and key questions for further investigation...
  18. pmc A thrombolytic regimen for high-risk deep venous thrombosis may substantially reduce the risk of postthrombotic syndrome in children
    Neil A Goldenberg
    University of Colorado at Denver and Health Sciences Center, Department of Pediatrics, Section of Hematology, Center for Cancer and Blood Disorders, The Children s Hospital, Denver, CO 80045, USA
    Blood 110:45-53. 2007
    ..These findings suggest that the use of a thrombolysis regimen may safely and substantially reduce the risk of PTS in children with occlusive lower-extremity acute DVT, providing the basis for a future clinical trial...
  19. doi The "parallel-cohort RCT": Novel design aspects and application in the Kids-DOTT trial of pediatric venous thromboembolism
    Neil A Goldenberg
    Dept of Pediatrics, Section of Hematology Oncology Bone Marrow Transplantation and Mountain States Regional Hemophilia and Thrombosis Center, Univ of Colorado Denver and The Children s Hospital, Aurora, CO, USA
    Contemp Clin Trials 31:131-3. 2010
    ....
  20. pmc Peri-procedural bridging with low molecular weight heparin in patients receiving warfarin for venous thromboembolism: a pediatric experience
    A Moruf
    University of Colorado School of Pharmacy, Aurora, CO, USA
    Thromb Res 130:612-5. 2012
    ..We sought to determine the risks of recurrent TE (both VTE and arterial TE [ATE]) and major bleeding with peri-procedural LMWH bridging in children receiving warfarin for VTE...
  21. doi Balancing risk and benefit in venous thromboembolism trials: concept for a bivariate endpoint trial design and analytic approach
    J M Kittelson
    Department of Biostatistics and Informatics, University of Colorado, Aurora, CO, USA
    J Thromb Haemost 11:1443-8. 2013
    ....
  22. doi Protein C deficiency
    N A Goldenberg
    Hemophilia and Thrombosis Center, Department of Pediatrics, University of Colorado Denver and The Children s Hospital, Aurora, CO, USA
    Haemophilia 14:1214-21. 2008
    ..Further research is needed to better delineate optimal preventive and therapeutic strategies...
  23. doi Antithrombotic treatments, outcomes, and prognostic factors in acute childhood-onset arterial ischaemic stroke: a multicentre, observational, cohort study
    Neil A Goldenberg
    Department of Pediatrics, University of Colorado Denver, Children s Hospital, and Mountain States Regional Hemophilia and Thrombosis Center, Aurora, CO, USA
    Lancet Neurol 8:1120-7. 2009
    ..We aimed to describe frequencies and predictors of acute treatments and early outcomes in the International Pediatric Stroke Study (IPSS), a large international series of childhood AIS...
  24. doi Tacrolimus as an alternative to cyclosporine in the maintenance phase of immunosuppressive therapy for severe aplastic anemia in children
    Abdulrahman Alsultan
    Center for Cancer and Blood Disorders, The Children s Hospital, University of Colorado Denver, Aurora, Colorado 80045, USA
    Pediatr Blood Cancer 52:626-30. 2009
    ....
  25. doi Varied opinions on thrombolysis for venous thromboembolism in infants and children: findings from a survey of pediatric hematology-oncology specialists
    Donald L Yee
    Department of Pediatrics, Hematology Oncology Section, Baylor College of Medicine, Houston, Texas 77030, USA
    Pediatr Blood Cancer 53:960-6. 2009
    ..Recent guidelines discourage routine use of thrombolytic agents for treatment of venous thromboembolism (VTE) in pediatric patients, but actual practice patterns are unknown...
  26. doi Venous thromboembolism in children
    Neil A Goldenberg
    Mountain States Regional Hemophilia and Thrombosis Center, Aurora, CO 80045 0507, USA
    Hematol Oncol Clin North Am 24:151-66. 2010
    ..Prognostic indicators and long-term outcomes are considered, with emphasis on available evidence underlying current knowledge and key questions for further investigation...
  27. doi High prevalence of thrombophilic traits in children with family history of thromboembolism
    Meghan J Calhoon
    Section of Hematology, Oncology, and Bone Marrow Transplantation, Department of Pediatrics, and the Mountain States Regional Hemophilia and Thrombosis Center, University of Colorado Denver and The Children s Hospital, Aurora, CO 80045, USA
    J Pediatr 157:485-9. 2010
    ....
  28. doi Impact of inherited thrombophilia on venous thromboembolism in children: a systematic review and meta-analysis of observational studies
    Guy Young
    Division of Hematology Oncology, Children s Hospital Los Angeles, Los Angeles, CA, USA
    Circulation 118:1373-82. 2008
    ..The aim of the present study was to estimate the impact of inherited thrombophilia (IT) on the risk of venous thromboembolism (VTE) onset and recurrence in children by a meta-analysis of published observational studies...

Research Grants2

  1. Clinical Investigation in Pediatric Thrombosis
    Neil Goldenberg; Fiscal Year: 2007
    ..Additionally, translational studies will seek to identify novel candidate protein risk factors and prognostic markers for venous thrombosis in children. ..