R J Goldberg

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. ncbi request reprint Increasing use of single and combination medical therapy in patients hospitalized for acute myocardial infarction in the 21st century: a multinational perspective
    Robert J Goldberg
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, 55 Lake Ave, Worcester, MA 01655, USA
    Arch Intern Med 167:1766-73. 2007
  2. ncbi request reprint Use of nonpharmacologic treatment approaches in patients with heart failure
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, 55 Lake Avenue North Worcester, MA 01655, United States
    Int J Cardiol 110:348-53. 2006
  3. ncbi request reprint Recent trends in the incidence rates of and death rates from atrial fibrillation complicating initial acute myocardial infarction: a community-wide perspective
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Mass 01655, USA
    Am Heart J 143:519-27. 2002
  4. ncbi request reprint Extent of, and factors associated with, delay to hospital presentation in patients with acute coronary disease (the GRACE registry)
    Robert J Goldberg
    University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Am J Cardiol 89:791-6. 2002
  5. ncbi request reprint A 25-year perspective into the changing landscape of patients hospitalized with acute myocardial infarction (the Worcester Heart Attack Study)
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Cardiol 94:1373-8. 2004
  6. ncbi request reprint Excess body weight, clinical profile, management practices, and hospital prognosis in men and women after acute myocardial infarction
    Robert J Goldberg
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Am Heart J 151:1297-304. 2006
  7. ncbi request reprint Long-term trends in the use of coronary reperfusion strategies in acute myocardial infarction: a community-wide perspective
    Robert J Goldberg
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    J Thromb Thrombolysis 23:163-71. 2007
  8. ncbi request reprint Survey of physician's attitudes and practices toward lipid-lowering management strategies
    Robert J Goldberg
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, Mass 01655, USA
    Cardiology 107:302-6. 2007
  9. ncbi request reprint Serum glucose levels and hospital outcomes in patients with acute myocardial infarction without prior diabetes: a community-wide perspective
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Coron Artery Dis 18:125-31. 2007
  10. ncbi request reprint Trends in community mortality due to coronary heart disease
    Robert J Goldberg
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Am Heart J 151:501-7. 2006

Research Grants

  1. Observational Study of Delay in Heart Failure
    Robert Goldberg; Fiscal Year: 2007
  2. Community Surveillance for Heart Failure
    Robert Goldberg; Fiscal Year: 2007

Collaborators

Detail Information

Publications102 found, 100 shown here

  1. ncbi request reprint Increasing use of single and combination medical therapy in patients hospitalized for acute myocardial infarction in the 21st century: a multinational perspective
    Robert J Goldberg
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, 55 Lake Ave, Worcester, MA 01655, USA
    Arch Intern Med 167:1766-73. 2007
    ..Current practice guidelines recommend the routine use of several effective cardiac medications in hospital survivors of acute myocardial infarction (AMI)...
  2. ncbi request reprint Use of nonpharmacologic treatment approaches in patients with heart failure
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, 55 Lake Avenue North Worcester, MA 01655, United States
    Int J Cardiol 110:348-53. 2006
    ....
  3. ncbi request reprint Recent trends in the incidence rates of and death rates from atrial fibrillation complicating initial acute myocardial infarction: a community-wide perspective
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Mass 01655, USA
    Am Heart J 143:519-27. 2002
    ..The purpose of this study was to examine the impact and trends over time of AF complicating initial AMI...
  4. ncbi request reprint Extent of, and factors associated with, delay to hospital presentation in patients with acute coronary disease (the GRACE registry)
    Robert J Goldberg
    University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Am J Cardiol 89:791-6. 2002
    ....
  5. ncbi request reprint A 25-year perspective into the changing landscape of patients hospitalized with acute myocardial infarction (the Worcester Heart Attack Study)
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Cardiol 94:1373-8. 2004
    ..Given the magnitude of AMI and evolving approaches to manage it, continued monitoring of these trends remains of considerable clinical and public health importance...
  6. ncbi request reprint Excess body weight, clinical profile, management practices, and hospital prognosis in men and women after acute myocardial infarction
    Robert J Goldberg
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Am Heart J 151:1297-304. 2006
    ..It is unclear, however, whether body weight is associated with the demographic and clinical profile, treatment of, and hospital prognosis after acute myocardial infarction (AMI)...
  7. ncbi request reprint Long-term trends in the use of coronary reperfusion strategies in acute myocardial infarction: a community-wide perspective
    Robert J Goldberg
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    J Thromb Thrombolysis 23:163-71. 2007
    ....
  8. ncbi request reprint Survey of physician's attitudes and practices toward lipid-lowering management strategies
    Robert J Goldberg
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, Mass 01655, USA
    Cardiology 107:302-6. 2007
    ..The purpose of the present study was to examine physician's attitudes and practices toward the use of different lipid-lowering management strategies in patients at increased risk for coronary heart disease (CHD)...
  9. ncbi request reprint Serum glucose levels and hospital outcomes in patients with acute myocardial infarction without prior diabetes: a community-wide perspective
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Coron Artery Dis 18:125-31. 2007
    ....
  10. ncbi request reprint Trends in community mortality due to coronary heart disease
    Robert J Goldberg
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Am Heart J 151:501-7. 2006
    ..A secondary study goal was to describe changes in death rates attributed to CHD over time separately in men and in women, in persons of different ages, and according to location of death...
  11. ncbi request reprint Trends in mortality attributed to heart failure in Worcester, Massachusetts, 1992 to 2001
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Cardiol 95:1324-8. 2005
    ..The results of this study suggest changing patterns in death rates due to HF in a large northeastern community...
  12. ncbi request reprint Recent magnitude of and temporal trends (1994-1997) in the incidence and hospital death rates of cardiogenic shock complicating acute myocardial infarction: the second national registry of myocardial infarction
    R J Goldberg
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester 01655, USA
    Am Heart J 141:65-72. 2001
    ..The purpose of this study was to examine recent (1994-1997) trends in the incidence of, and hospital death rates from, cardiogenic shock complicating acute myocardial infarction from a large, multihospital national perspective...
  13. ncbi request reprint Incidence and hospital death rates associated with heart failure: a community-wide perspective
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Med 118:728-34. 2005
    ....
  14. ncbi request reprint Decade-long trends and factors associated with time to hospital presentation in patients with acute myocardial infarction: the Worcester Heart Attack study
    R J Goldberg
    Department of Medicine, University of Massachusetts Medical School, 55 Lake Ave N, Worcester, MA 01655, USA
    Arch Intern Med 160:3217-23. 2000
    ..Duration of prehospital delay in patients with acute myocardial infarction (AMI) is receiving increasing attention given the time-dependent benefits associated with prompt use of coronary reperfusion strategies...
  15. ncbi request reprint Duration of, and temporal trends (1994-1997) in, prehospital delay in patients with acute myocardial infarction: the second National Registry of Myocardial Infarction
    R J Goldberg
    Department of Medicine, University of Massachusetts Medical School, Worcester 01655, USA
    Arch Intern Med 159:2141-7. 1999
    ..Extent of delay in seeking medical care in persons with acute myocardial infarction (AMI) is receiving increasing attention, given the time-dependent benefits associated with early administration of coronary reperfusion therapy...
  16. ncbi request reprint Twenty-two year (1975 to 1997) trends in the incidence, in-hospital and long-term case fatality rates from initial Q-wave and non-Q-wave myocardial infarction: a multi-hospital, community-wide perspective
    M I Furman
    Department of Medicine, University of Massachusetts Medical School, Worcester 01655, USA
    J Am Coll Cardiol 37:1571-80. 2001
    ....
  17. ncbi request reprint Temporal trends (1986-1997) in cholesterol level assessment and management practices in patients with acute myocardial infarction: a population-based perspective
    J Yarzebski
    Division of Cardiovascular Medicine, University of Massachusetts Medical School, 55 Lake Ave N, Worcester, MA 01655, USA
    Arch Intern Med 161:1521-8. 2001
    ..It is unclear what proportion of patients have their serum cholesterol levels measured during hospitalization for AMI and are given hypolipidemic therapy...
  18. ncbi request reprint Ten-year trends in the incidence, treatment, and outcome of Q-wave myocardial infarction
    H L Dauerman
    Cardiovascular Division, University of Massachusetts Memorial Medical Center, Worcester 01655, USA
    Am J Cardiol 86:730-5. 2000
    ..The decrease in mortality occurs in the setting of broader use of reperfusion and adjunctive therapy (including primary angioplasty)...
  19. ncbi request reprint Outcomes and early revascularization for patients > or = 65 years of age with cardiogenic shock
    H L Dauerman
    Cardiovascular Division, University of Massachusetts Memorial Medical Center and Medical School, Worcester, Massachusetts 01655, USA
    Am J Cardiol 87:844-8. 2001
    ....
  20. ncbi request reprint Temporal trends in cardiogenic shock complicating acute myocardial infarction
    R J Goldberg
    Department of Medicine, University of Massachusetts Medical School, Worcester 01655, USA
    N Engl J Med 340:1162-8. 1999
    ..We studied the incidence of cardiogenic shock complicating acute myocardial infarction and in-hospital death rates among patients with this condition in a single community from 1975 through 1997...
  21. ncbi request reprint Decade-long trends (1986 to 1997) in the medical treatment of patients with acute myocardial infarction: A community-wide perspective
    F Spencer
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester 01655, USA
    Am Heart J 142:594-603. 2001
    ..Despite encouraging increases in the use of several of these agents, considerable opportunities for increased utilization remain...
  22. ncbi request reprint A two-decades (1975 to 1995) long experience in the incidence, in-hospital and long-term case-fatality rates of acute myocardial infarction: a community-wide perspective
    R J Goldberg
    Department of Medicine, University of Massachusetts Medical School, Worcester 01655, USA
    J Am Coll Cardiol 33:1533-9. 1999
    ....
  23. ncbi request reprint Two-decade-long trends (1975-1997) in the incidence, hospitalization, and long-term death rates associated with complete heart block complicating acute myocardial infarction: a community-wide perspective
    Frederick A Spencer
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Mass 01655, USA
    Am Heart J 145:500-7. 2003
    ..Limited population-based data exist describing recent, and changes with time therein, incidence and case-fatality rates associated with CHB complicating AMI...
  24. pmc A 30-year perspective (1975-2005) into the changing landscape of patients hospitalized with initial acute myocardial infarction: Worcester Heart Attack Study
    Kevin C Floyd
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Circ Cardiovasc Qual Outcomes 2:88-95. 2009
    ....
  25. ncbi request reprint Changes over time in the use of aspirin in patients hospitalized with acute myocardial infarction (1975 to 1997): a population-based perspective
    Elizabeth A Jackson
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Mass 01655, USA
    Am Heart J 144:259-68. 2002
    ..The purpose of this study was to examine 2 decade-long trends in the use of aspirin and associated outcomes in patients hospitalized with acute myocardial infarction...
  26. pmc Clinical features, treatment practices, and hospital and long-term outcomes of older patients hospitalized with decompensated heart failure: The Worcester Heart Failure Study
    Jane S Saczynski
    Department of Medicine, Division of GeriatricMedicine, University of Massachusetts Medical School, Biotech Four, Suite 315, 377 Plantation Street, Worcester, MA 01605, USA
    J Am Geriatr Soc 57:1587-94. 2009
    ..To examine age-specific differences in clinical presentation, receipt of therapeutic practices and lifestyle recommendations, and hospital and long-term survival in patients hospitalized for acute heart failure HF...
  27. ncbi request reprint Age and sex differences in the treatment of patients with initial acute myocardial infarction: a community-wide perspective
    Leslie R Harrold
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, Mass 01655, USA
    Cardiology 99:39-46. 2003
    ..The objectives of our study were to determine whether women are treated differently than men and whether age acts as a potential effect modifier of any observed associations...
  28. ncbi request reprint Age and the utilization of cardiac catheterization following uncomplicated first acute myocardial infarction treated with thrombolytic therapy (The Second National Registry of Myocardial Infarction [NRMI-2])
    F A Spencer
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Cardiol 88:107-11. 2001
    ..The efficacy and cost effectiveness of this strategy in these patients has not yet been determined in clinical trials...
  29. ncbi request reprint Differences in discharge medication after acute myocardial infarction in patients with HMO and fee-for-service medical insurance
    D McCormick
    Section for Health Services Research, Division of General Medicine/Primary Care/Geriatrics, University of Massachusetts Medical School, Worcester 01655, USA
    J Gen Intern Med 14:73-81. 1999
    ..Differential adoption, over time, of evidence-based prescribing practices for medications between HMO and FFS patients who have had a myocardial infarction warrants further study...
  30. ncbi request reprint Temporal trends and associated factors of inpatient cardiac rehabilitation in patients with acute myocardial infarction: a community-wide perspective
    F A Spencer
    Department of Medicine, University of Massachusetts Medical School, Worcester, 01655, USA
    J Cardiopulm Rehabil 21:377-84. 2001
    ..Inpatient CR often represents cardiac patients' first exposure to risk factor modification education and acts as a gateway to outpatient programs...
  31. ncbi request reprint Prevalence and quality of warfarin use for patients with atrial fibrillation in the long-term care setting
    D McCormick
    Department of Medicine, Cambridge Hospital, 1493 Cambridge St, Cambridge, MA 02139, USA
    Arch Intern Med 161:2458-63. 2001
    ..Evidence-based clinical practice guidelines recommend the use of warfarin sodium for stroke prevention in most patients with atrial fibrillation (AF) who do not have risk factors for hemorrhagic complications, irrespective of age...
  32. ncbi request reprint The impact of the stent era on the management strategy for acute myocardial infarction: A population-based perspective
    H L Dauerman
    Cardiovascular Division, University of Massachusetts Memorial Medical Center and University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Catheter Cardiovasc Interv 51:255-8. 2000
    ..This resulted in a higher-risk profile of patients referred for invasive management of AMI in the stent era. Cathet. Cardiovasc. Intervent. 51:255-258, 2000...
  33. ncbi request reprint Recent and temporal trends (1975 to 1999) in the treatment, hospital, and long-term outcomes of Hispanic and non-Hispanic white patients hospitalized with acute myocardial infarction: a population-based perspective
    Jorge Yarzebski
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester 01655, USA
    Am Heart J 147:690-7. 2004
    ..Extremely limited population-based data are available describing recent and temporal trends in the characteristics, treatment, and outcomes of Hispanic and non-Hispanic white patients hospitalized with acute myocardial infarction (AMI)...
  34. ncbi request reprint Treatment practices and outcomes of patients with established peripheral arterial disease hospitalized with acute myocardial infarction in a community setting
    Frederick A Spencer
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Am Heart J 153:140-6. 2007
    ..The objectives of our population-based study were to examine the hospital and long-term outcomes, as well as the use of different treatment practices, among patients with established PAD who were hospitalized with AMI...
  35. ncbi request reprint Seasonal distribution of acute myocardial infarction in the second National Registry of Myocardial Infarction
    F A Spencer
    Cardiovascular Thrombosis Research Center, Department of Medicine, University of Massachusetts Medical Center, Worcester 01655, USA
    J Am Coll Cardiol 31:1226-33. 1998
    ..This observational study sought to determine whether cases of acute myocardial infarction (AMI) reported to the second National Registry of Myocardial Infarction (NRMI-2) varied by season...
  36. ncbi request reprint Use of disease-modifying therapies in patients hospitalized with heart failure: a population-based perspective
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Mass, USA
    Am J Med 120:98.e1-8. 2007
    ..The purpose of our study was to describe the use of different cardiac medications in 2463 patients with new-onset HF who were discharged from all greater Worcester, Massachusetts, hospitals during 2000...
  37. ncbi request reprint Six-month outcomes in a multinational registry of patients hospitalized with an acute coronary syndrome (the Global Registry of Acute Coronary Events [GRACE])
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Cardiol 93:288-93. 2004
    ..These data suggest the need for better long-term medical management and more intense follow-up of patients with an ACS to improve their long-term outlook...
  38. ncbi request reprint Trends in atrial fibrillation complicating acute myocardial infarction
    Jane S Saczynski
    University of Massachusetts, Medical School, Worcester, MA, USA
    Am J Cardiol 104:169-74. 2009
    ..Increased surveillance and targeted therapeutic approaches appear warranted for these high-risk patients...
  39. pmc Risk factors and comorbidities in a community-wide sample of patients hospitalized with acute systolic or diastolic heart failure: the Worcester Heart Failure Study
    Marcello Chinali
    Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Coron Artery Dis 21:137-43. 2010
    ..Few epidemiological studies have examined differences in the prevalence of risk factors and comorbidities in patients with systolic heart failure (HF), as compared with those with diastolic HF...
  40. pmc Body mass index, treatment practices, and mortality in patients with acute heart failure
    Timothy P Fitzgibbons
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Coron Artery Dis 20:536-43. 2009
    ..Among patients presenting with acute HF, however, differences in clinical characteristics, treatment regimens, and short-term prognosis of varying weights are largely unknown, particularly from a broader population-based perspective...
  41. pmc Thirty-year trends (1975-2005) in the magnitude, patient characteristics, and hospital outcomes of patients with acute myocardial infarction complicated by ventricular fibrillation
    Robert J Goldberg
    Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Am J Cardiol 102:1595-601. 2008
    ..In conclusion, our results indicate that the incidence and hospital death rates associated with VF have decreased during recent years...
  42. ncbi request reprint Recent trends in hospital management practices and prognosis after acute myocardial infarction in patients with kidney disease
    Vandana Menon
    Department of Medicine, Division of Nephrology, Tufts University School of Medicine New England Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 94:1290-3. 2004
    ....
  43. ncbi request reprint Age-specific differences in the use of thrombolytic therapy and hospital outcomes in patients with acute myocardial infarction: a community-wide perspective
    Omar Ali
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    J Thromb Thrombolysis 14:5-14. 2002
    ....
  44. pmc Declining length of stay for patients hospitalized with AMI: impact on mortality and readmissions
    Jane S Saczynski
    University of Massachusetts Medical School, Worcester, MA, USA
    Am J Med 123:1007-15. 2010
    ....
  45. pmc Thirty-year trends (1975-2005) in the magnitude and hospital death rates associated with complete heart block in patients with acute myocardial infarction: a population-based perspective
    Hoa L Nguyen
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Am Heart J 156:227-33. 2008
    ....
  46. ncbi request reprint Communitywide trends in the use and outcomes associated with beta-blockers in patients with acute myocardial infarction: the Worcester Heart Attack Study
    Helme Silvet
    Department of Medicine, Harvard Medical School, Boston, Mass, USA
    Arch Intern Med 163:2175-83. 2003
    ..Data are also limited about the characteristics of patients with AMI who do not receive beta-blockers. This study examines more than 2 decades of trends in the use of beta-blockers in hospitalized patients with AMI...
  47. ncbi request reprint Decade-long changes in the use of combination evidence-based medical therapy at discharge for patients surviving acute myocardial infarction
    Frederick A Spencer
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Am Heart J 150:838-44. 2005
    ....
  48. pmc Management and outcomes of renal disease and acute myocardial infarction
    Paul A Santolucito
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Am J Med 123:847-55. 2010
    ....
  49. ncbi request reprint Elevated leukocyte count and adverse hospital events in patients with acute coronary syndromes: findings from the Global Registry of Acute Coronary Events (GRACE)
    Mark I Furman
    Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Mass 01655, USA
    Am Heart J 147:42-8. 2004
    ..To examine the association between elevated leukocyte count and hospital mortality and heart failure in patients enrolled in the multinational, observational Global Registry of Acute Coronary Events (GRACE)...
  50. pmc Factors associated with adverse outcomes in outpatients presenting with pulmonary embolism: the Worcester Venous Thromboembolism Study
    Frederick A Spencer
    Department of Medicine, McMaster University Medical Center, and Thrombosis and Atherosclerosis Research Institute, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
    Circ Cardiovasc Qual Outcomes 3:390-4. 2010
    ..However, subjects enrolled in these studies may not be representative of patients seen in the community setting...
  51. pmc Symptom presentation in patients hospitalized with acute heart failure
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Clin Cardiol 33:E73-80. 2010
    ....
  52. pmc Long-term trends (1986-2003) in the use of coronary reperfusion strategies in patients hospitalized with acute myocardial infarction in central Massachusetts
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Int J Cardiol 131:83-9. 2008
    ..Limited contemporary data are available about changing trends in the use of coronary reperfusion strategies, particularly from a population-based perspective...
  53. pmc Disparities in combination drug therapy use in older adults with coronary heart disease: a cross-sectional time-series in a nationally representative US sample
    Jennifer Tjia
    Department of Medicine, University of Massachusetts Medical School, Division of Geriatric Medicine, Worcester, Massachusetts 01605, USA
    Drugs Aging 27:149-58. 2010
    ..Despite evidence of effective combination drug therapy for secondary prevention of coronary heart disease (CHD), older adults with this condition remain undertreated...
  54. pmc The Worcester Venous Thromboembolism study: a population-based study of the clinical epidemiology of venous thromboembolism
    Frederick A Spencer
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    J Gen Intern Med 21:722-7. 2006
    ..While there have been marked advances in diagnostic and therapeutic strategies for venous thromboembolism, our understanding of its clinical epidemiology is based on studies conducted more than a decade ago...
  55. pmc Thirty-year trends (1975 to 2005) in the magnitude of, management of, and hospital death rates associated with cardiogenic shock in patients with acute myocardial infarction: a population-based perspective
    Robert J Goldberg
    Department of Medicine, University of Massachusetts Medical School, Worcester, 01655, USA
    Circulation 119:1211-9. 2009
    ....
  56. ncbi request reprint Use of heparins in Non-ST-elevation acute coronary syndromes
    Joel M Gore
    University of Massachusetts Medical School, Worcester, Mass 01655, USA
    Am J Med 120:63-71. 2007
    ..We describe the use of antithrombotic therapy in the management of patients with acute coronary syndromes...
  57. pmc Trends in prehospital delay in patients with acute myocardial infarction (from the Worcester Heart Attack Study)
    Jane S Saczynski
    University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Am J Cardiol 102:1589-94. 2008
    ..In conclusion, results of this population-based study suggest that a large proportion of patients with AMI continue to show prolonged prehospital delay...
  58. pmc Upper extremity deep vein thrombosis: a community-based perspective
    Frederick A Spencer
    Department of Medicine, University of Massachusetts Medical School, Worcester, USA
    Am J Med 120:678-84. 2007
    ..The purpose of this study was to examine the magnitude, risk factors, management strategies, and outcomes in a population-based investigation of patients with upper, as compared with lower, extremity deep vein thrombosis diagnosed in 1999...
  59. pmc Changing trends in the evaluation of ejection fraction in patients hospitalized with acute myocardial infarction: the Worcester Heart Attack Study
    Paul A Santolucito
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Am Heart J 155:485-93. 2008
    ....
  60. ncbi request reprint Use of combination evidence-based medical therapy prior to acute myocardial infarction (from the National Registry of Myocardial Infarction-4)
    Frederick A Spencer
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Am J Cardiol 96:922-6. 2005
    ..In conclusion, data from this large national registry have indicated that most patients with a history of CAD were not receiving the recommended combination of cardiac medications before their AMI...
  61. ncbi request reprint Declining length of hospital stay for acute myocardial infarction and postdischarge outcomes: a community-wide perspective
    Frederick A Spencer
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, USA
    Arch Intern Med 164:733-40. 2004
    ....
  62. ncbi request reprint Impact of aspirin on presentation and hospital outcomes in patients with acute coronary syndromes (The Global Registry of Acute Coronary Events [GRACE])
    Frederick A Spencer
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Am J Cardiol 90:1056-61. 2002
    ....
  63. ncbi request reprint Leukocytosis and adverse hospital outcomes after acute myocardial infarction
    Vandana Menon
    Department of Medicine, Division of Clinical Care Research, Tufts University School of Medicine New England Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 92:368-72. 2003
    ..These findings suggest that the WBC count should be considered an important prognostic factor associated with adverse hospital outcomes in patients with AMI...
  64. ncbi request reprint Trends (1986 to 1999) in the incidence and outcomes of in-hospital stroke complicating acute myocardial infarction (The Worcester Heart Attack Study)
    Frederick A Spencer
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Cardiol 92:383-8. 2003
    ..26, 95% confidence interval 2.49 to 7.31). The results of this community-wide study provide insights into recent trends in the development of acute stroke after AMI and into the profile of high-risk patients...
  65. pmc Narrowing gender differences in procedure use for acute myocardial infarction: insights from the Worcester heart attack study
    Leslie R Harrold
    Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Gen Intern Med 18:423-31. 2003
    ..To examine age-specific gender differences and trends over time in the management of patients with acute myocardial infarction (AMI)...
  66. ncbi request reprint Influence of age on assessment of diastolic function by Doppler tissue imaging
    Dennis A Tighe
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Cardiol 91:254-7. 2003
  67. ncbi request reprint Heterogeneity in the management and outcomes of patients with acute myocardial infarction complicated by heart failure: the National Registry of Myocardial Infarction
    Frederick A Spencer
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Mass 01655, USA
    Circulation 105:2605-10. 2002
    ..A secondary objective was to determine differences in demographic and clinical characteristics, treatment, and hospital death rates in patients presenting with HF compared with those developing HF after presentation...
  68. ncbi request reprint Hospital transfer of patients with acute myocardial infarction: the effects of age, race, and insurance type
    Jerry H Gurwitz
    Meyers Primary Care Institute, Fallon Healthcare System and University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
    Am J Med 112:528-34. 2002
    ..The objectives of this study were to assess the frequency of transfer to another hospital and to determine whether nonmedical factors, such as age, sex, race, and insurance status, are associated with transfer...
  69. ncbi request reprint Do-not-resuscitate orders in patients hospitalized with acute myocardial infarction: the Worcester Heart Attack Study
    Elizabeth A Jackson
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, and Meyers Primary Care Institute, Worcester, USA
    Arch Intern Med 164:776-83. 2004
    ..The objectives of this study were to describe use of DNR orders, treatment approaches, and hospital outcomes in patients with acute myocardial infarction...
  70. ncbi request reprint Association of statin therapy with outcomes of acute coronary syndromes: the GRACE study
    Frederick A Spencer
    Department of Medicine Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Ann Intern Med 140:857-66. 2004
    ..Statins administered early in patients with acute coronary syndromes may lead to modest reductions in recurrent ischemic events...
  71. ncbi request reprint Implications of diabetes in patients with acute coronary syndromes. The Global Registry of Acute Coronary Events
    Kristen Franklin
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester 01655, USA
    Arch Intern Med 164:1457-63. 2004
    ..There are limited data describing the presenting characteristics, management, and outcomes of diabetic and nondiabetic patients with an acute coronary syndrome (ACS)...
  72. ncbi request reprint Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: national registry of myocardial infarction
    Frederick A Spencer
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Arch Intern Med 164:2162-8. 2004
    ..It has been suggested that withdrawal of statin therapy during an acute coronary syndrome may attenuate any benefits of pretreatment, thereby providing indirect evidence of the importance of their non-lipid-lowering effects...
  73. ncbi request reprint Occurrence of acute myocardial infarction in Worcester, Massachusetts, before, during, and after the terrorists attacks in New York City and Washington, DC, on 11 September 2001
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Am J Cardiol 95:258-60. 2005
    ....
  74. ncbi request reprint Outcomes with the use of glycoprotein IIb/IIIa inhibitors in non-ST-segment elevation acute coronary syndromes
    O H Dabbous
    Center for Outcomes Research, University of Massachusetts Medical School, 365 Plantation Street, Suite 185, Worcester, MA 01605, USA
    Heart 94:159-65. 2008
    ....
  75. pmc Prehospital transport of patients with acute myocardial infarction: a community-wide perspective
    Robert J Goldberg
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Heart Lung 37:266-74. 2008
    ..A secondary study aim was to describe the demographic and clinical characteristics of patients with AMI transported to metropolitan Worcester hospitals by EMS, compared with those transported by other means, and their hospital outcomes...
  76. doi request reprint Pulmonary artery catheterization in patients with acute coronary syndromes
    Christopher P Ruisi
    Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Am Heart J 158:170-6. 2009
    ..Using data from the multinational Global Registry of Acute Coronary Events, we examined trends in PAC use among patients hospitalized for an ACS and the association between PAC and hospital outcomes...
  77. pmc Trends in the use of echocardiography and left ventriculography to assess left ventricular ejection fraction in patients hospitalized with acute myocardial infarction
    Samuel W Joffe
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Am Heart J 158:185-92. 2009
    ..The purpose of this study was to evaluate trends in the use of ventriculography and echocardiography to measure EF in a community sample of patients hospitalized with AMI...
  78. pmc A community-wide perspective into changing trends in the utilization of diagnostic and interventional procedures in patients hospitalized with acute myocardial infarction
    Jessica Hahn
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Am Heart J 153:594-605. 2007
    ..We examined the demographic and clinical characteristics of patients who received these diagnostic and interventional procedures and determined whether the profile of patients undergoing these procedures had changed over time...
  79. pmc Epidemiology of decompensated heart failure in a single community in the northeastern United States
    Robert J Goldberg
    Department of Medicine, University of Massachusetts, Medical School, Worcester, Massachusetts, USA
    Am J Cardiol 104:377-82. 2009
    ....
  80. ncbi request reprint Patient-specific decisions about hormone replacement therapy in postmenopausal women
    N F Col
    Division of Clinical Decision Making, Informatics, and Telemedicine, Department of Medicine, New England Medical Center and Tufts University School of Medicine, Boston, Mass 02111, USA
    JAMA 277:1140-7. 1997
    ..To examine the effect of hormone replacement therapy on life expectancy in postmenopausal women with different risk profiles for heart disease, breast cancer, and hip fracture...
  81. ncbi request reprint Asymptomatic thrombophilia--a family affair
    F A Spencer
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Thromb Haemost 3:457-8. 2005
  82. ncbi request reprint Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction
    M I Furman
    Center for Platelet Function Studies, Division of Cardiovascular Medicine, Worcester, Massachusetts 01655, USA
    J Am Coll Cardiol 38:1002-6. 2001
    ..We investigated whether elevated levels of circulating monocyte-platelet aggregates (MPA) can be used to identify patients with acute myocardial infarction (AMI)...
  83. ncbi request reprint The relationship of patient characteristics to physician delivery of advice to stop smoking
    J K Ockene
    Department of Medicine, University of Massachusetts Medical School, Worcester 01605
    J Gen Intern Med 2:337-40. 1987
    ..Knowledge of factors that affect the provision of advice to stop smoking can be used to enhance the physician's role in smoking intervention...
  84. ncbi request reprint Comparison of utilization of statin therapy at hospital discharge and six-month outcomes in patients with an acute coronary syndrome and serum low-density lipoprotein>or=100 mg/dl versus<100 mg/dl
    Frederick A Spencer
    Department of Medicine, McMaster University, Faculty of Health Sciences, Hamilton, Ontario, Canada, and Coronary Care Unit, Concord Hospital, Sydney, Australia
    Am J Cardiol 100:913-8. 2007
    ....
  85. ncbi request reprint Activated clotting times in the setting of eptifibatide use during percutaneous coronary intervention
    Harold L Dauerman
    Cardiac Unit, University of Vermont College of Medicine, Burlington, Vermont 05401, USA
    J Thromb Thrombolysis 13:127-32. 2002
    ..The impact of the short acting glycoprotein (GP) IIb-IIIa inhibitor, eptifibatide, on ACT measurements has not been studied...
  86. ncbi request reprint Use of the invasive management strategy for patients with non-Q-wave myocardial infarction: an observational database report from the Worcester Heart Attack Study
    Harold L Dauerman
    Cardiac Unit, University of Vermont College of Medicine, Burlington, VT 05401, USA
    Am Heart J 143:1033-9. 2002
    ..However, the broader use and impact of the invasive management approach has not been established for patients with acute coronary syndromes beyond the relatively narrow patient populations studied in randomized, clinical trials...
  87. ncbi request reprint Baseline characteristics, management practices, and in-hospital outcomes of patients hospitalized with acute coronary syndromes in the Global Registry of Acute Coronary Events (GRACE)
    Philippe Gabriel Steg
    Hopital Bichat, Paris, France
    Am J Cardiol 90:358-63. 2002
    ..0001), and recurrent angina with ST-segment changes occurred before discharge in 10%, 10%, and 9% of patients, respectively (p = 0.2644). GRACE provides a detailed and comprehensive global description of the spectrum of patients with ACS...
  88. ncbi request reprint Revascularization, stenting, and outcomes of patients with acute myocardial infarction complicated by cardiogenic shock
    Harold L Dauerman
    University of Vermont College of Medicine, Fletcher Allen Health Care, Burlington, Vermont 05401, USA
    Am J Cardiol 90:838-42. 2002
    ..In this multinational registry study, coronary stenting was the most powerful independent predictor of hospital survival...
  89. ncbi request reprint Effectiveness of primary percutaneous coronary intervention compared with that of thrombolytic therapy in elderly patients with acute myocardial infarction
    Rajendra H Mehta
    University of Michigan, Ann Arbor, Mich, USA
    Am Heart J 147:253-9. 2004
    ....
  90. ncbi request reprint Bleeding complications in patients with anemia and acute myocardial infarction
    Harold L Dauerman
    Division of Cardiology, University of Vermont, Burlington, VT, USA
    Am J Cardiol 96:1379-83. 2005
    ..89, 95% confidence interval 0.64 to 1.23). In conclusion, these findings suggest that bleeding complications are a potential mechanism for increased mortality among patients who have anemia and present with AMI...
  91. ncbi request reprint A validated prediction model for all forms of acute coronary syndrome: estimating the risk of 6-month postdischarge death in an international registry
    Kim A Eagle
    Department of Internal Medicine, University of Michigan Health System, Ann Arbor, USA
    JAMA 291:2727-33. 2004
    ..Accurate estimation of risk for untoward outcomes after patients have been hospitalized for an acute coronary syndrome (ACS) may help clinicians guide the type and intensity of therapy...
  92. ncbi request reprint Treating patients with acute coronary syndromes with aggressive antiplatelet therapy (from the Global Registry of Acute Coronary Events)
    Michael J Lim
    Saint Louis University, St Louis, Missouri, USA
    Am J Cardiol 96:917-21. 2005
    ..Although no differences in hospital death rates were evident in patients receiving triple therapy, this population was at significantly increased risk of major bleeding episodes during hospitalization...
  93. ncbi request reprint Gender and age differences in chief complaints of acute myocardial infarction (Worcester Heart Attack Study)
    Kerry A Milner
    Yale University School of Nursing, New Haven, Connecticut, USA
    Am J Cardiol 93:606-8. 2004
    ..Overall, a large proportion of women and men whose AMI was ultimately diagnosed did not present with chest pain as their chief complaint...
  94. ncbi request reprint Women's Ischemic Syndrome Evaluation: current status and future research directions: report of the National Heart, Lung and Blood Institute workshop: October 2-4, 2002: Section 3: diagnosis and treatment of acute cardiac ischemia: gender issues
    Elizabeth G Nabel
    Circulation 109:e50-2. 2004
  95. ncbi request reprint Use of proven therapies in non-ST-elevation acute coronary syndromes according to evidence-based risk stratification
    Gustavo B F Oliveira
    Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil
    Am Heart J 153:493-9. 2007
    ..Our objective was to evaluate the relationship between risk stratification and therapeutic decision making in patients with non-ST-segment elevation acute coronary syndromes...
  96. ncbi request reprint Determinants and prognostic impact of heart failure complicating acute coronary syndromes: observations from the Global Registry of Acute Coronary Events (GRACE)
    Philippe Gabriel Steg
    Centre Hospitalier Universitaire Bichat Beaujon, Assistance Publique Hopitaux de Paris, France
    Circulation 109:494-9. 2004
    ..Few data are available on the impact of heart failure (HF) across all types of acute coronary syndromes (ACS)...
  97. ncbi request reprint Sex differences in survival after acute myocardial infarction in patients with diabetes mellitus (Worcester Heart Attack Study)
    Amber Crowley
    Section of Emergency Medicine, Yale University School of Medicine, New Haven, Conn, USA
    Am Heart J 146:824-31. 2003
    ....
  98. ncbi request reprint Decompensated heart failure in the setting of kidney dysfunction: a community-wide perspective
    Rovshan M Ismailov
    Department of Community Health, Brown University, Providence, RI, USA
    Nephron Clin Pract 107:c147-55. 2007
    ....
  99. ncbi request reprint Does comorbidity account for the excess mortality in patients with major bleeding in acute myocardial infarction?
    Frederick A Spencer
    Department of Medicine, McMaster University, Faculty of Health Sciences, 1200 Main St W, Hamilton, Canada, L8N 3Z5
    Circulation 116:2793-801. 2007
    ..Because these data are not generalizable to all patients with acute myocardial infarction, we sought to better understand the scope of this problem in a "real-world" setting...
  100. ncbi request reprint Comparison of outcomes of patients with acute coronary syndromes with and without atrial fibrillation
    Rajendra H Mehta
    Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor 48105, USA
    Am J Cardiol 92:1031-6. 2003
    ..However, only new-onset AF is an independent predictor of in-hospital adverse events in patients with ACS...
  101. pmc Impact of do-not-resuscitation orders on quality of care performance measures in patients hospitalized with acute heart failure
    Joline L T Chen
    Renal Section, Boston University School of Medicine, Boston, MA 02118, USA
    Am Heart J 156:78-84. 2008
    ..The goals of this observational study were to describe the use of DNR orders and their impact on treatment approaches in residents of a large New England metropolitan area hospitalized with acute heart failure...

Research Grants2

  1. Observational Study of Delay in Heart Failure
    Robert Goldberg; Fiscal Year: 2007
    ..These data will be useful in the development of future educational and treatment strategies designed to improve outcomes in patients with heart failure. ..
  2. Community Surveillance for Heart Failure
    Robert Goldberg; Fiscal Year: 2007
    ..The continued extension of this surveillance project will provide insights and guidance to public health and clinical efforts of HF and in monitoring trends in this newly emerging chronic disease. ..