Mark S Gold

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi request reprint Prescription opioid abuse and dependence among physicians: hypotheses and treatment
    Lisa J Merlo
    Department of Psychiatry, University of Florida, Gainesville, FL 32610 0183, USA
    Harv Rev Psychiatry 16:181-94. 2008
  2. ncbi request reprint Fentanyl abuse and dependence: further evidence for second hand exposure hypothesis
    Mark S Gold
    Department of Psychiatry, Division of Addiction Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0183, USA
    J Addict Dis 25:15-21. 2006
  3. ncbi request reprint Occupational exposure and addictions for physicians: case studies and theoretical implications
    Mark S Gold
    University of Florida College of Medicine, Gainesville, FL, USA
    Psychiatr Clin North Am 27:745-53. 2004
  4. doi request reprint Methods in drug abuse neuroproteomics: methamphetamine psychoproteome
    Firas H Kobeissy
    Department of Psychiatry, University of Florida, Gainesville, FL, USA
    Methods Mol Biol 566:217-28. 2009
  5. ncbi request reprint Second-hand exposure to aerosolized intravenous anesthetics propofol and fentanyl may cause sensitization and subsequent opiate addiction among anesthesiologists and surgeons
    Priscilla F McAuliffe
    Department of Surgery, University of Florida College of Medicine, Gainesville, 32610, USA
    Med Hypotheses 66:874-82. 2006
  6. doi request reprint Fentanyl and propofol exposure in the operating room: sensitization hypotheses and further data
    Lisa J Merlo
    Department of Psychiatry, University of Florida College of Medicine, Gainesville, FL 32610 0183, USA
    J Addict Dis 27:67-76. 2008
  7. doi request reprint Effects of fentanyl dose and exposure duration on the affective and somatic signs of fentanyl withdrawal in rats
    Jiang Liu
    Department of Pharmaceutics, University of Florida, Gainesville, FL 32610, USA
    Neuropharmacology 55:812-8. 2008
  8. doi request reprint Methods in systems biology of experimental methamphetamine drug abuse
    Firas H Kobeissy
    Department of Psychiatry, Center for Neuroproteomics and Biomarkers Research, McKnight Brain Institute of the University of Florida, Gainesville, FL, USA
    Methods Mol Biol 662:303-16. 2010
  9. doi request reprint Methods in tobacco abuse: proteomic changes following second-hand smoke exposure
    Joy Guingab-Cagmat
    Department of Psychiatry, Center for Neuroproteomics and Biomarkers Research at the Evelyn F and William L McKnight Brain Institute, Gainesville, FL, USA
    Methods Mol Biol 829:329-48. 2012
  10. ncbi request reprint The effects of buprenorphine on fentanyl withdrawal in rats
    Adrie W Bruijnzeel
    Department of Psychiatry, McKnight Brain Institute, College of Medicine, University of Florida, 100 S Newell Dr, 100256, Gainesville, FL 32610 0244, USA
    Psychopharmacology (Berl) 191:931-41. 2007

Collaborators

Detail Information

Publications81

  1. ncbi request reprint Prescription opioid abuse and dependence among physicians: hypotheses and treatment
    Lisa J Merlo
    Department of Psychiatry, University of Florida, Gainesville, FL 32610 0183, USA
    Harv Rev Psychiatry 16:181-94. 2008
    ..Given the extremely positive outcomes demonstrated by specialized programs for treating impaired professionals, it is recommended that their methods be disseminated and utilized in treatment centers for the general public...
  2. ncbi request reprint Fentanyl abuse and dependence: further evidence for second hand exposure hypothesis
    Mark S Gold
    Department of Psychiatry, Division of Addiction Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0183, USA
    J Addict Dis 25:15-21. 2006
    ..We are developing an animal model for second hand exposure and additional studies of the operating room and cardiac anesthesiologists are underway...
  3. ncbi request reprint Occupational exposure and addictions for physicians: case studies and theoretical implications
    Mark S Gold
    University of Florida College of Medicine, Gainesville, FL, USA
    Psychiatr Clin North Am 27:745-53. 2004
    ..These studies should include biological measures, such as blood levels in exposed workers, and sensitive assays that quantitatively assess levels of exposure in the workplace...
  4. doi request reprint Methods in drug abuse neuroproteomics: methamphetamine psychoproteome
    Firas H Kobeissy
    Department of Psychiatry, University of Florida, Gainesville, FL, USA
    Methods Mol Biol 566:217-28. 2009
    ..These methods and protocols are discussed in the paradigm of acute model of methamphetamine drug abuse and can be applied to other models of substance abuse such as to MDMA or cocaine...
  5. ncbi request reprint Second-hand exposure to aerosolized intravenous anesthetics propofol and fentanyl may cause sensitization and subsequent opiate addiction among anesthesiologists and surgeons
    Priscilla F McAuliffe
    Department of Surgery, University of Florida College of Medicine, Gainesville, 32610, USA
    Med Hypotheses 66:874-82. 2006
    ..We conclude that the potential exists for chronic exposure to low levels of airborne intravenously administered drugs. Further studies are under way to determine the significance of this exposure...
  6. doi request reprint Fentanyl and propofol exposure in the operating room: sensitization hypotheses and further data
    Lisa J Merlo
    Department of Psychiatry, University of Florida College of Medicine, Gainesville, FL 32610 0183, USA
    J Addict Dis 27:67-76. 2008
    ..Suggestions for reducing secondhand exposure in the operating room are discussed...
  7. doi request reprint Effects of fentanyl dose and exposure duration on the affective and somatic signs of fentanyl withdrawal in rats
    Jiang Liu
    Department of Pharmaceutics, University of Florida, Gainesville, FL 32610, USA
    Neuropharmacology 55:812-8. 2008
    ..These studies suggest that the magnitude and duration of the negative affective signs of fentanyl withdrawal depend on the dose of fentanyl administered and not on the duration of fentanyl administration...
  8. doi request reprint Methods in systems biology of experimental methamphetamine drug abuse
    Firas H Kobeissy
    Department of Psychiatry, Center for Neuroproteomics and Biomarkers Research, McKnight Brain Institute of the University of Florida, Gainesville, FL, USA
    Methods Mol Biol 662:303-16. 2010
    ..These methods and protocols are discussed in the paradigm of the acute model of METH drug abuse and neuronal cell culture and can be applied on other models of substance abuse such as on MDMA or cocaine...
  9. doi request reprint Methods in tobacco abuse: proteomic changes following second-hand smoke exposure
    Joy Guingab-Cagmat
    Department of Psychiatry, Center for Neuroproteomics and Biomarkers Research at the Evelyn F and William L McKnight Brain Institute, Gainesville, FL, USA
    Methods Mol Biol 829:329-48. 2012
    ..Moreover, combining smoke exposure with proteomics can lead to the discovery of biomarkers that can be potentially useful tools in screening, early diagnosis, prevention, and treatment of diseases caused by SHS...
  10. ncbi request reprint The effects of buprenorphine on fentanyl withdrawal in rats
    Adrie W Bruijnzeel
    Department of Psychiatry, McKnight Brain Institute, College of Medicine, University of Florida, 100 S Newell Dr, 100256, Gainesville, FL 32610 0244, USA
    Psychopharmacology (Berl) 191:931-41. 2007
    ..Fentanyl is a potent mu-opioid receptor agonist that is widely used for the treatment of severe chronic pain. Discontinuation of fentanyl administration has been shown to induce a negative emotional state...
  11. ncbi request reprint Food addiction and obesity: evidence from bench to bedside
    Yijun Liu
    Division of Global Tobacco, Alcohol, Obesity and Health Research, University of Florida, Department of Psychiatry and McKnight Brain Institute, PO Box 100256, Gainesville, FL 32610 0256, USA
    J Psychoactive Drugs 42:133-45. 2010
    ..The acquired drive for great food and relative weakness of the satiety signal would cause an imbalance between the drive and hunger/reward centers in the brain and their regulation...
  12. pmc Methamphetamine- and trauma-induced brain injuries: comparative cellular and molecular neurobiological substrates
    Mark S Gold
    Center for Neuroproteomics and Biomarkers Research, McKnight Brain Institute of the University of Florida, Gainesville, Florida 32610, USA
    Biol Psychiatry 66:118-27. 2009
    ....
  13. ncbi request reprint The role of corticotropin-releasing factor-like peptides in cannabis, nicotine, and alcohol dependence
    Adrie W Bruijnzeel
    Department of Psychiatry, University of Florida, McKnight Brain Institute, 100 S Newell Dr PO Box 100256, Gainesville, FL 32610, USA
    Brain Res Brain Res Rev 49:505-28. 2005
    ....
  14. pmc Tobacco smoke exposure induces nicotine dependence in rats
    Elysia Small
    Department of Psychiatry, College of Medicine, McKnight Brain Institute, University of Florida, 100 S Newell Dr, PO Box 100256, Gainesville, FL 32610, USA
    Psychopharmacology (Berl) 208:143-58. 2010
    ..Therefore, animal models are needed that allow the investigation of chronic exposure to the full spectrum of tobacco smoke constituents...
  15. doi request reprint Identification of tyrosine nitration in UCH-L1 and GAPDH
    Joy D Guingab-Cagmat
    Center of Innovative Research, Banyan Biomarkers, Inc, Alachua, FL, USA
    Electrophoresis 32:1692-705. 2011
    ..Targeted analysis of endogenous UCH-L1 and GAPDH nitration was then conducted in an in vivo second-hand smoke rat model to evaluate the utility of this approach...
  16. pmc Low dopamine function in attention deficit/hyperactivity disorder: should genotyping signify early diagnosis in children?
    Mark S Gold
    Department of Psychiatry, School of Medicine and McKnight Brain Institute, University of Florida, Gainesville, FL
    Postgrad Med 126:153-77. 2014
    ..With the goals of improving treatment of patients with ADHD and SUD prevention, we encourage further work in both genetic diagnosis and novel treatment approaches. ..
  17. doi request reprint Hypothesizing that designer drugs containing cathinones ("bath salts") have profound neuro-inflammatory effects and dangerous neurotoxic response following human consumption
    Kenneth Blum
    Department of Psychiatry and McKnight Brain Institute, University of Florida College of Medicine, Gainesville, FL 32610 0256, USA
    Med Hypotheses 81:450-5. 2013
    ....
  18. pmc Lifetime psychiatric and substance use disorders among impaired physicians in a physicians health program: comparison to a general treatment population: psychopathology of impaired physicians
    Linda B Cottler
    Department of Epidemiology, Colleges of Medicine and Public Health and Health Professions, University of Florida, Gainesville, Florida 32611, USA
    J Addict Med 7:108-12. 2013
    ..We determined differences in lifetime substance use, and abuse/dependence as well as other psychiatric disorders, comparing physicians undergoing monitoring with a general population that had sought treatment for substance use...
  19. doi request reprint Methods in drug abuse models: comparison of different models of methamphetamine paradigms
    Firas H Kobeissy
    Division of Addiction Medicine, Department of Psychiatry, Center for Neuroproteomics and Biomarkers Research at the Evelyn F and William L McKnight Brain Institute, University of Florida, Gainesville, FL, USA
    Methods Mol Biol 829:269-78. 2012
    ..In comparing the models, this chapter briefly considers the METH-induced neurotoxic effects associated with each METH administration paradigm and the behavioral changes observed...
  20. doi request reprint Methadone- and heroin-related deaths in Florida
    Noni A Graham
    University of Florida College of Medicine Department of Psychiatry, Division of Addiction Medicine, Evelyn F and William L McKnight Brain Institute, Gainesville, Florida 32610, USA
    Am J Drug Alcohol Abuse 34:347-53. 2008
    ..Treatment with methadone, for both pain and opioid dependence, should be preceded by an abuse liability evaluation. Attempts to minimize diversion should be implemented...
  21. doi request reprint Neuro-chemical activation of brain reward meso-limbic circuitry is associated with relapse prevention and drug hunger: a hypothesis
    Kenneth Blum
    Department of Psychiatry, University of Florida College of Medicine and McKnight Brain Institute, Gainesville, FL, USA
    Med Hypotheses 76:576-84. 2011
    ..The logical standard of care should focus on detoxifying, stabilizing and returning the patient to the pre-loss of control or pre-addiction neurochemical state...
  22. ncbi request reprint Reward circuitry dopaminergic activation regulates food and drug craving behavior
    Kenneth Blum
    Department of Psychiatry, and McKnight Brain Institute, University of Florida, College of Medicine, Gainesville, Florida, USA
    Curr Pharm Des 17:1158-67. 2011
    ..Finally, utilizing the long term dopaminergic activation approach will ultimately lead to a common safe and effective modality to treat RDS behaviors including aberrant food and drug craving behaviors...
  23. doi request reprint Psychiatric research: psychoproteomics, degradomics and systems biology
    Firas H Kobeissy
    McKnight Brain Institute, Department of Psychiatry, University of Florida College of Medicine, Gainesville, FL 32611, USA
    Expert Rev Proteomics 5:293-314. 2008
    ..Finally, we will discuss the emerging role of systems biology and its current use in the field of neuroscience and its integral role in establishing a comprehensive understanding of specific brain disorders and brain function in general...
  24. ncbi request reprint Calpain- and caspase-mediated alphaII-spectrin and tau proteolysis in rat cerebrocortical neuronal cultures after ecstasy or methamphetamine exposure
    Matthew W Warren
    Center for Traumatic Brain Injury Studies, Department of Neuroscience, McKnight Brain Institute of the University of Florida, Gainesville, FL, USA
    Int J Neuropsychopharmacol 10:479-89. 2007
    ..The ability of the protease inhibitors to reduce the damage caused by these drugs suggests that the treatment arsenal could include similar drugs as possible tools to combat the drug-induced neurotoxicity in vivo...
  25. pmc Comparing the effects of food restriction and overeating on brain reward systems
    Nicole M Avena
    University of Florida, Department of Psychiatry, Gainesville, FL 32610, USA
    Exp Gerontol 48:1062-7. 2013
    ..Age-related loss of appetite, decreased eating, and caloric restriction are hypothesized to be associated with changes in the prevalence of substance misuse, abuse, and dependence seen in this cohort. ..
  26. pmc Altered functional brain networks in Prader-Willi syndrome
    Yi Zhang
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an, Shaanxi, China
    NMR Biomed 26:622-9. 2013
    ....
  27. pmc Identification of proteins sensitive to thermal stress in human neuroblastoma and glioma cell lines
    Guilian Xu
    Department of Neuroscience, Santa Fe Health Alzheimer s Disease Research Center, University of Florida, Gainesville, FL, USA
    PLoS ONE 7:e49021. 2012
    ..Collectively, this study identifies human neural proteins that lose solubility upon heat-shock. These proteins may represent components of the human proteome that are vulnerable to misfolding in settings of proteostasis stress...
  28. doi request reprint The mirage of impairing drug concentration thresholds: a rationale for zero tolerance per se driving under the influence of drugs laws
    Gary M Reisfield
    Department of Psychiatry, University of Florida College of Medicine, Gainesville, FL, USA
    J Anal Toxicol 36:353-6. 2012
    ..We propose specific legislation to address alcohol- and drug-impaired driving in the United States...
  29. doi request reprint Qualitative versus quantitative methods in psychiatric research
    Mahdi Razafsha
    Department of Psychiatry, Center for Neuroproteomics and Biomarkers Research at the Evelyn F and William L McKnight Brain Institute, University of Florida, Gainesville, FL, USA
    Methods Mol Biol 829:49-62. 2012
    ..By applying both methods of research, scientists can take advantage of interpretative characteristics of qualitative methods as well as experimental dimensions of quantitative methods...
  30. doi request reprint Investigating the effects of low dose alcohol on neural timing using functional MRI
    Nelson J Klahr
    Department of Psychiatry and McKnight Brain Institute, University of Florida, Gainesville, Florida 32610 0256, USA
    J Magn Reson Imaging 34:1045-52. 2011
    ..To examine human brain function related to the perception of short time intervals before and after ingesting a low dosage of alcohol (0.25 g/kg)...
  31. doi request reprint Psychoproteomic analysis of rat cortex following acute methamphetamine exposure
    Firas H Kobeissy
    Center for Neuroproteomics and Biomarkers Research, Department of Psychiatry, College of Medicine, McKnight Brain Institute of the University of Florida, Gainesville, Florida 32610, USA
    J Proteome Res 7:1971-83. 2008
    ..Lastly, we used these differentially expressed protein subsets to construct a "psychoproteomic" spectrum map in an effort to uncover potential protein interactions relevant to acute METH neurotoxicity...
  32. doi request reprint Opiate prescription medication dependence and pain perceptions
    Norman S Miller
    University of Florida College of Medicine, Department of Psychiatry, Gainesville, FL, USA
    J Addict Dis 26:65-71. 2007
    ..Identification of addiction and detoxification is the proper approach to pain management in chronic opiate administration...
  33. ncbi request reprint Body mass index and alcohol use
    Katie D Kleiner
    College of Medicine, University of Florida, Gainesville, FL 32610, USA
    J Addict Dis 23:105-18. 2004
    ..We have hypothesized that drugs of abuse compete with food for brain reward sites. Overeating and obesity may act as protective factors reducing drug reward and addiction...
  34. ncbi request reprint Tobacco and psychiatric dual disorders
    Noni A Graham
    Public Health Research Group, Division of Addiction Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0183, USA
    J Addict Dis 26:5-12. 2007
    ....
  35. pmc Alcohol consumption associated with collegiate American football pre-game festivities
    Lisa J Merlo
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Drug Alcohol Depend 116:242-5. 2011
    ....
  36. ncbi request reprint Food addiction and neuroimaging
    Yi Zhang
    Department of Psychiatry, McKnight Brain Institute, University of Florida, 100 Newell Drive, PO Box 100256, Gainesville, FL 32610, USA
    Curr Pharm Des 17:1149-57. 2011
    ....
  37. ncbi request reprint Antagonism of CRF receptors prevents the deficit in brain reward function associated with precipitated nicotine withdrawal in rats
    Adrie W Bruijnzeel
    Department of Psychiatry, McKnight Brain Institute, University of Florida, Gainesville, FL 32610, USA
    Neuropsychopharmacology 32:955-63. 2007
    ..These data provide support for the hypothesis that a hyperactivity of brain CRF systems may at least partly mediate the initiation of the negative affective aspects of nicotine withdrawal...
  38. ncbi request reprint Concurrent calpain and caspase-3 mediated proteolysis of alpha II-spectrin and tau in rat brain after methamphetamine exposure: a similar profile to traumatic brain injury
    Matthew W Warren
    University of Florida Department of Psychiatry, McKnight Brain Institute, University of Florida, Gainesville, FL 32610, USA
    Life Sci 78:301-9. 2005
    ..Use of calpain and caspase proteolytic inhibitors may be useful in preventing methamphetamine-induced neurotoxicity...
  39. ncbi request reprint Calpain and caspase proteolytic markers co-localize with rat cortical neurons after exposure to methamphetamine and MDMA
    Matthew W Warren
    Center for Traumatic Brain Injury Studies, Department of Neuroscience, McKnight Brain Institute of the University of Florida, Gainesville, FL 32610, USA
    Acta Neuropathol 114:277-86. 2007
    ..These findings support the hypothesis that calpains and caspases mediate PCD in cortical neurons following club drug abuse and, more importantly, appear to contribute to the neuropathology suffered by abusers...
  40. ncbi request reprint Problematic internet use: proposed classification and diagnostic criteria
    Nathan A Shapira
    Department of Psychiatry, E f and W L McKnight Brain Institute, University of Florida, Gainesville, Florida 32610 0383, USA
    Depress Anxiety 17:207-16. 2003
    ..For these reasons, we propose specific diagnostic criteria that will allow for consistent identification and assist in further study of this behavior...
  41. doi request reprint Is speeding a form of gambling in adolescents?
    David S Husted
    Department of Psychiatry, University of Florida College of Medicine, P O Box 100256, Gainesville, FL 32610 0256, USA
    J Gambl Stud 22:209-19. 2006
    ..Our data indicate a relationship between risky driving, gambling, and other risk-taking behaviors in adolescents, and support the hypothesis that speeding may be a form of gambling behavior in this age group...
  42. pmc Further developments in the neurobiology of food and addiction: update on the state of the science
    Nicole M Avena
    Department of Psychiatry, University of Florida, College of Medicine, Gainesville, Florida, USA
    Nutrition 28:341-3. 2012
    ....
  43. ncbi request reprint Overlaps in the nosology of substance abuse and overeating: the translational implications of "food addiction"
    Nicole M Avena
    University of Florida, College of Medicine, Department of Psychiatry, Gainesville, FL 32610, USA
    Curr Drug Abuse Rev 4:133-9. 2011
    ..With this background and evidence in mind, we conclude this article with a discussion as to how "food addiction" research may translate into clinical strategies and pharmaceutical treatments useful in curtailing overeating...
  44. ncbi request reprint Drug withdrawal and hyperphagia: lessons from tobacco and other drugs
    Paula J Edge
    Department of Psychiatry, College of Medicine and McKnight Brain Institute, University of Florida, Gainesville, FL 32610 0183, USA
    Curr Pharm Des 17:1173-9. 2011
    ..Additionally, prenatal programming for addiction is explored. Lessons from successful drug treatment are elucidated and potential pharmaceutical targets for hyperphagia and obesity are suggested...
  45. ncbi request reprint Neurobiological mechanisms in addictive and psychiatric disorders
    Adrie W Bruijnzeel
    Department of Psychiatry, University of Florida College of Medicine, P O Box 100183, Gainesville, FL 32610 0183, USA
    Psychiatr Clin North Am 27:661-74. 2004
    ..Conversely, professional treatment of pre-existing psychiatric disorders may decrease the use of illicit substances...
  46. pmc Hypothesizing dopaminergic genetic antecedents in schizophrenia and substance seeking behavior
    Kenneth Blum
    Department of Psychiatry and McKnight Brain Institute, University of Florida College of Medicine, Gainesville, FL, USA Department of Clinical Neurology, PATH Research Foundation, New York, NY, USA Department of Genomics, IGENE, LLC, Austin, TX, USA Department of Psychiatry, Human Integrated Services Unit University of Vermont Center for Clinical and Translational Science, College of Medicine, Burlington, VT, USA Dominion Diagnostics, LLC, North Kingstown, RI, USA Department of Addiction Research and Therapy, Malibu Beach Recovery Center, Malibu Beach, CA, USA RD Solutions, LLC, Research Center, Austin, TX, USA Department of Nutrigenomics, RD Solutions, LLC, La Jolla, CA, USA Electronic address
    Med Hypotheses 82:606-14. 2014
    ....
  47. doi request reprint Do dopaminergic gene polymorphisms affect mesolimbic reward activation of music listening response? Therapeutic impact on Reward Deficiency Syndrome (RDS)
    Kenneth Blum
    Department of Psychiatry, University of Florida, College of Medicine and McKnight Brain Institute, Gainesville, Florida, USA
    Med Hypotheses 74:513-20. 2010
    ..Ross et al. [18] found that music therapy appears to be a novel motivational tool in a severely impaired inpatient sample of patients with co-occurring mental illness and addiction...
  48. ncbi request reprint Interaction of satiety and reward response to food stimulation
    G Andrew James
    University of Florida College of Medicine, Department of Psychiatry, Gainesville, FL 32610 0256, USA
    J Addict Dis 23:23-37. 2004
    ..We review the interaction between central satiety signals and reward responses to food stimuli and discuss the implications of this research for understanding the causes of obesity...
  49. ncbi request reprint Are physicians and medical students prepared to educate patients about alcohol consumption?
    Kimberly Frost-Pineda
    Department of Psychiatry, University of Florida College of Medicine, USA
    J Addict Dis 23:1-13. 2004
    ....
  50. ncbi request reprint A marked increase in cocaine-related deaths in the State of Florida: precursor to an epidemic?
    Bruce A Goldberger
    William R Maples Center for Forensic Medicine, Florida Emergency Mortuary Operations Response System, University of Florida College of Medicine, Department of Pathology, USA
    J Addict Dis 26:113-6. 2007
    ..Public health interventions are necessary to prevent another full-fledged epidemic...
  51. ncbi request reprint Food addiction and cues in prader-willi syndrome
    Karen M von Deneen
    From the Departments of Psychiatry and Neuroscience, McKnight Brain Institute The University of Florida, Gainesville, FL
    J Addict Med 3:19-25. 2009
    ..Appetite control is poor in PWS, thus food cues play a major role in its regulation. Hence, PWS may be the genetic model of choice for obesity...
  52. ncbi request reprint Changes in leptin, ghrelin, growth hormone and neuropeptide-Y after an acute model of MDMA and methamphetamine exposure in rats
    Firas H Kobeissy
    University of Florida College of Medicine, Gainesville, FL 32610, USA
    Addict Biol 13:15-25. 2008
    ..Future studies should be performed to see how chronic, low dose drug administration would affect hormone levels and try to answer questions about the physiological mechanisms involved in the anorexic paradigm observed in drug use...
  53. ncbi request reprint Brief educational intervention to improve medical student competence in managing patients exposed to secondhand smoke
    Lisa J Merlo
    a Department of Psychology, University of Florida, Gainesville, Florida, USA
    Subst Abus 35:163-7. 2014
    ..The goal of this study was to develop an SHS-related educational intervention for medical students, with the purpose of improving knowledge regarding consequences of SHS exposure, and increasing intent to screen patients for exposure...
  54. pmc Food consumption and weight gain after cessation of chronic amphetamine administration
    Caitlin A Orsini
    Department of Psychiatry, McKnight Brain Institute, University of Florida College of Medicine, Gainesville, FL 32610 0256, USA
    Appetite 78:76-80. 2014
    ..The current findings may reflect amphetamine-induced sensitization of mechanisms involved in reward motivation, suggesting that weight gain following drug cessation in humans could be due to similar mechanisms. ..
  55. pmc PATHOS: a brief screening application for assessing sexual addiction
    Patrick J Carnes
    Pine Grove Behavioral Health Services, University of Southern Mississippi, Hattiesburg, MS, USA
    J Addict Med 6:29-34. 2012
    ..Sexual addiction is estimated to afflict up to 3% to 6% of the population. However, many clinicians lack clear criteria for detecting potential cases...
  56. ncbi request reprint Marijuana and tobacco: a major connection?
    Laura Michelle Tullis
    University of Florida, P O Box 100183, Gainesville, FL 32610 0183, USA
    J Addict Dis 22:51-62. 2003
    ..Our research with university students is suggesting that cigarette-smoking initiation often follows or coincides with marijuana...
  57. doi request reprint From bedside to bench and back again: a 30-year saga
    Mark S Gold
    Department of Psychiatry, College of Medicine, University of Florida, Gainesville, FL 32611, USA
    Physiol Behav 104:157-61. 2011
    ..The Gold lab is investigating working models for pathological attachment to eating and food addiction. New pharmacological treatments which interfere with food reinforcement may be the next step...
  58. ncbi request reprint Women tipping the scale during pregnancy: a special population for obesity interventions, treatments and clinical trials
    Nancy S Hardt
    Obstetrics Gynecology and Pathology, Department of Psychiatry Division of Addiction Medicine, University of Florida, Gainesville, FL 32610 0183, USA
    Curr Pharm Des 17:1143-4. 2011
    ..In order to prevent obesity in women and their offspring, clinical interventions and trials need to be developed for women before and in between pregnancies...
  59. doi request reprint Crossroads of pain and addiction
    John A Bailey
    Pain and Addiction Medicine in the Division of Addiction Medicine, Department of Psychiatry, University of Florida s Springhill Health Center, Gainesville, FL32606, USA
    Pain Med 11:1803-18. 2010
    ..Similarly, addiction medicine programs often offer little training in pain management. What follows is a review of the intersection between these two specialties from the perspective of clinicians that practice both...
  60. ncbi request reprint Performance enhancing, non-prescription use of Ritalin: a comparison with amphetamines and cocaine
    Stanislay I Svetlov
    Department of Physiological Sciences, University of Florida, Gainesville, FL 32610, USA
    J Addict Dis 26:1-6. 2007
    ..In this mini-review, we discuss psychopharmacological and behavioral aspects, and outline neurochemical mechanisms that may provoke Ritalin abuse, addiction and adverse effects compared to amphetamines and cocaine...
  61. doi request reprint The Salted Food Addiction Hypothesis may explain overeating and the obesity epidemic
    James A Cocores
    Department of Psychiatry, University of Florida College of Medicine and McKnight Brain Institute, Gainesville, FL, USA
    Med Hypotheses 73:892-9. 2009
    ..One plausible explanation for the controversy that surrounds the causes and clinical management of obesity is the notion that overeating and obesity may only be a couple of "symptoms" associated with a yet to be discovered medical disorder...
  62. ncbi request reprint Caffeine content of decaffeinated coffee
    Rachel R McCusker
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida 32610 0275, USA
    J Anal Toxicol 30:611-3. 2006
    ..Additionally, further exploration is merited for the possible physical dependence potential of low doses of caffeine such as those concentrations found in decaffeinated coffee...
  63. ncbi request reprint Naltrexone augments the effects of nicotine replacement therapy in female smokers
    Joanne A Byars
    University of Florida, Gainesviile, FL 32610, USA
    J Addict Dis 24:49-60. 2005
    ..We hypothesized that naltrexone, which has been used to successfully treat opioid and alcohol dependence, when combined with nicotine replacement therapy (NRT) and psychosocial therapy (PT) may enhance smoking cessation rates in women...
  64. ncbi request reprint Opioid treatment for chronic back pain and its association with addiction
    Robert L DuPont
    Ann Intern Med 147:349; author reply 349-50. 2007
  65. ncbi request reprint Adolescent drug addiction treatment and weight gain
    Candace C Hodgkins
    Gateway Community Services, Inc, 555 Stockton Street, Jacksonville, FL 32224, USA
    J Addict Dis 23:55-65. 2004
    ..Furthermore, significant interactions between tobacco use and primary substance use disorder with weight gain was demonstrated by multivariate analysis of variance...
  66. ncbi request reprint Ecstasy toxicity: a comparison to methamphetamine and traumatic brain injury
    Matthew W Warren
    College of Medicine, University of Florida, Gainsville, FL 32610, USA
    J Addict Dis 25:115-23. 2006
    ..Neurotoxicity is still evident after 72 hours. Furthermore, apoptosis of the liver is seen 72 hours after ecstasy use. Use of protease inhibitors may be useful in preventing ecstasy-induced toxicity...
  67. doi request reprint Increased assessment and monitoring needed for patients receiving methadone
    Lisa J Merlo
    Am J Med 121:e23; author repply e25. 2008
  68. doi request reprint Response to "Comorbid psychiatric diagnoses and their association with cocaine-induced psychosis in cocaine-dependent subjects"
    Lisa J Merlo
    Am J Addict 17:247-8; author reply 249-50. 2008
  69. ncbi request reprint Physician suicide and drug abuse
    Mark S Gold
    Am J Psychiatry 162:1390; author reply 1390. 2005
  70. pmc Methamphetamine causes microglial activation in the brains of human abusers
    Yoshimoto Sekine
    Molecular Neuropsychiatry Branch, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland 21224, USA
    J Neurosci 28:5756-61. 2008
    ..These results suggest that chronic self-administration of methamphetamine can cause reactive microgliosis in the brains of human methamphetamine abusers, a level of activation that appears to subside over longer periods of abstinence...
  71. pmc Socioeconomic inequities often translate into health inequalities
    Sarah Vinson
    J Natl Med Assoc 98:816-7. 2006
  72. ncbi request reprint Depression-related improvement with vardenafil for erectile response
    Mark S Gold
    Am J Psychiatry 163:1449. 2006
  73. ncbi request reprint Symptoms of ADHD or marijuana use?
    Noni A Graham
    Am J Psychiatry 164:973; author reply 973-4. 2007
  74. ncbi request reprint The relationship between obesity and drug use
    Matthew W Warren
    Am J Psychiatry 164:1268; author reply 1268-9. 2007
  75. ncbi request reprint Regarding "Is cigarette smoking a gateway to alcohol and illicit drug use disorders? A study of youths with and without attention deficit hyperactivity disorder"
    Mark S Gold
    Biol Psychiatry 60:1166; author reply 1166. 2006
  76. ncbi request reprint Effects of sustained gamma-hydroxybutyrate treatments on spontaneous and evoked firing activity of locus coeruleus norepinephrine neurons
    Steven T Szabo
    Laboratory of Molecular Pathophysiology, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Biol Psychiatry 55:934-9. 2004
    ..Of interest, the activity of locus coeruleus neurons is a reflective index of these above mentioned behavioral states...
  77. ncbi request reprint Brief intervention for medical inpatients with unhealthy alcohol use
    Lisa J Merlo
    Ann Intern Med 147:589-90; author reply 590. 2007
  78. ncbi request reprint Physicians and drug screening
    Mark S Gold
    J Adolesc Health 39:154-5; author reply 155. 2006
  79. ncbi request reprint Speed, cocaine, and other psychostimulants death rates
    Mark S Gold
    Am J Cardiol 100:1184. 2007
  80. ncbi request reprint Problem doctors: is there a system-level solution?
    Mark S Gold
    Ann Intern Med 144:861-2; author reply 863. 2006
  81. ncbi request reprint Can drug design inhibit abuse?
    John J Coleman
    Prescription Drug Research Center, Fairfax, Virginia 22030, USA
    J Psychoactive Drugs 37:343-62. 2005
    ..In every instance, drugs employing abuse-resistant designs were found to have significantly lower levels of abuse than comparator drugs without such designs...