BRIAN GOLD

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. pmc White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, KY, USA Magnetic Resonance Imaging and Spectroscopy Center, University of Kentucky, Lexington, KY, USA Sanders Brown Center on Aging, University of Kentucky, Lexington, KY, USA Electronic address
    Neurobiol Aging 35:2263-71. 2014
  2. pmc Lifelong bilingualism contributes to cognitive reserve against white matter integrity declines in aging
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, KY 40536, USA Magnetic Resonance Imaging and Spectroscopy Center, University of Kentucky, Lexington, KY 40536, USA Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA Electronic address
    Neuropsychologia 51:2841-6. 2013
  3. pmc Lifelong bilingualism maintains neural efficiency for cognitive control in aging
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, Kentucky 40536, USA
    J Neurosci 33:387-96. 2013
  4. pmc Multimodal imaging evidence for axonal and myelin deterioration in amnestic mild cognitive impairment
    Brian T Gold
    Department of Anatomy and Neurobiology, Chandler Medical Center, University of Kentucky, Lexington, KY, USA
    J Alzheimers Dis 31:S19-31. 2012
  5. pmc White matter integrity and vulnerability to Alzheimer's disease: preliminary findings and future directions
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky Medical Center, Lexington, KY 40536, USA
    Biochim Biophys Acta 1822:416-22. 2012
  6. pmc Alterations in multiple measures of white matter integrity in normal women at high risk for Alzheimer's disease
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, KY 40536, USA
    Neuroimage 52:1487-94. 2010
  7. pmc Aging influences the neural correlates of lexical decision but not automatic semantic priming
    Brian T Gold
    Department of Anatomy and Neurobiology, Chandler Medical Center, University of Kentucky, Lexington, KY 40536, USA
    Cereb Cortex 19:2671-9. 2009
  8. pmc Age-related slowing of task switching is associated with decreased integrity of frontoparietal white matter
    Brian T Gold
    Department of Anatomy and Neurobiology, Chandler Medical Center, University of Kentucky School of Medicine, Lexington, KY 40536 0298, USA
    Neurobiol Aging 31:512-22. 2010
  9. ncbi request reprint Neural correlates of morphological decomposition during visual word recognition
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky School of Medicine, Lexington, KY 40536 0298, USA
    J Cogn Neurosci 19:1983-93. 2007
  10. pmc Human experience seeking correlates with hippocampus volume: convergent evidence from manual tracing and voxel-based morphometry
    Sarah B Martin
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, KY, USA
    Neuropsychologia 45:2874-81. 2007

Detail Information

Publications20

  1. pmc White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, KY, USA Magnetic Resonance Imaging and Spectroscopy Center, University of Kentucky, Lexington, KY, USA Sanders Brown Center on Aging, University of Kentucky, Lexington, KY, USA Electronic address
    Neurobiol Aging 35:2263-71. 2014
    ..Our results link lower WM microstructural integrity in CN older adults with CSF biomarkers of Alzheimer's disease and suggest that this association in the fornix may be independent of volumetric measures...
  2. pmc Lifelong bilingualism contributes to cognitive reserve against white matter integrity declines in aging
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, KY 40536, USA Magnetic Resonance Imaging and Spectroscopy Center, University of Kentucky, Lexington, KY 40536, USA Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA Electronic address
    Neuropsychologia 51:2841-6. 2013
    ..There were no group differences in GM volume. Our results suggest that lifelong bilingualism contributes to CR against WM integrity declines in aging. ..
  3. pmc Lifelong bilingualism maintains neural efficiency for cognitive control in aging
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, Kentucky 40536, USA
    J Neurosci 33:387-96. 2013
    ..These results suggest that lifelong bilingualism offsets age-related declines in the neural efficiency for cognitive control processes...
  4. pmc Multimodal imaging evidence for axonal and myelin deterioration in amnestic mild cognitive impairment
    Brian T Gold
    Department of Anatomy and Neurobiology, Chandler Medical Center, University of Kentucky, Lexington, KY, USA
    J Alzheimers Dis 31:S19-31. 2012
    ..These results suggest that WM microstructural declines provide unique information not captured by atrophy measures that may aid the magnetic resonance imaging contribution to aMCI detection...
  5. pmc White matter integrity and vulnerability to Alzheimer's disease: preliminary findings and future directions
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky Medical Center, Lexington, KY 40536, USA
    Biochim Biophys Acta 1822:416-22. 2012
    ..With continued refinement of imaging methods, DTI holds promise as a method to aid identification of presymptomatic AD. This article is part of a Special Issue entitled: Imaging Brain Aging and Neurodegenerative disease...
  6. pmc Alterations in multiple measures of white matter integrity in normal women at high risk for Alzheimer's disease
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, KY 40536, USA
    Neuroimage 52:1487-94. 2010
    ..These results suggest that disconnection of MTL-neocortical fiber pathways represents a very early event in the course of AD and suggest that demyelination may represent one contributing mechanism...
  7. pmc Aging influences the neural correlates of lexical decision but not automatic semantic priming
    Brian T Gold
    Department of Anatomy and Neurobiology, Chandler Medical Center, University of Kentucky, Lexington, KY 40536, USA
    Cereb Cortex 19:2671-9. 2009
    ....
  8. pmc Age-related slowing of task switching is associated with decreased integrity of frontoparietal white matter
    Brian T Gold
    Department of Anatomy and Neurobiology, Chandler Medical Center, University of Kentucky School of Medicine, Lexington, KY 40536 0298, USA
    Neurobiol Aging 31:512-22. 2010
    ..These findings identify decreased integrity of frontoparietal WM as one mechanism contributing to age-related increases in RT switch costs...
  9. ncbi request reprint Neural correlates of morphological decomposition during visual word recognition
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky School of Medicine, Lexington, KY 40536 0298, USA
    J Cogn Neurosci 19:1983-93. 2007
    ..These findings provide a neurobiological basis for a purely structural morphemic segmentation mechanism operating at early stages of visual word recognition...
  10. pmc Human experience seeking correlates with hippocampus volume: convergent evidence from manual tracing and voxel-based morphometry
    Sarah B Martin
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, KY, USA
    Neuropsychologia 45:2874-81. 2007
    ..In addition, these results provide new ecologically relevant evidence for a link between right anterior hippocampus and novelty processing...
  11. pmc Speed of lexical decision correlates with diffusion anisotropy in left parietal and frontal white matter: evidence from diffusion tensor imaging
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky School of Medicine, Lexington, KY 40536 0298, USA
    Neuropsychologia 45:2439-46. 2007
    ..These results provide new microstructural evidence demonstrating that speed of lexical decision is associated with the degree to which portions of frontal and parietal WM are directionally oriented...
  12. ncbi request reprint Dissociation of automatic and strategic lexical-semantics: functional magnetic resonance imaging evidence for differing roles of multiple frontotemporal regions
    Brian T Gold
    Department of Anatomy and Neurobiology, Chandler Medical Center, University of Kentucky, Lexington, Kentucky 40536 0298, USA
    J Neurosci 26:6523-32. 2006
    ..These studies provide reproducible evidence for a neural dissociation between three well established components of the lexical-semantic processing system...
  13. ncbi request reprint Differing neuropsychological and neuroanatomical correlates of abnormal reading in early-stage semantic dementia and dementia of the Alzheimer type
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky, MN214 Chandler Medical Center, Lexington, KY 40536 0298, USA
    Neuropsychologia 43:833-46. 2005
    ....
  14. pmc Functional response in ventral temporal cortex differentiates mild cognitive impairment from normal aging
    Brian T Gold
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, 40536 0298, USA
    Hum Brain Mapp 31:1249-59. 2010
    ..These results showed that a disrupted functional response in the ventral temporal lobe accurately distinguishes individuals with MCI from NS, a finding which may have implications for identifying seniors at risk for cognitive decline...
  15. pmc Evidence that volume of anterior medial temporal lobe is reduced in seniors destined for mild cognitive impairment
    Sarah B Martin
    Department of Anatomy and Neurobiology, Chandler Medical Center, University of Kentucky, Lexington, KY 40536 0298, USA
    Neurobiol Aging 31:1099-106. 2010
    ..93). These results show that smaller normalized volumes of anterior medial temporal lobe structures contribute to the development of MCI, a finding which may have implications for identifying seniors at risk for cognitive decline...
  16. pmc Brain responses to repeated visual experience among low and high sensation seekers: role of boredom susceptibility
    Yang Jiang
    Department of Behavioral Science, University of Kentucky College of Medicine, Lexington, KY 40536, USA
    Psychiatry Res 173:100-6. 2009
    ..The distinct profiles of brain responses to repeated visual experience in high and low sensation seekers provide evidence that individual differences in neural adaptation can be linked to personality dimensions...
  17. pmc White matter diffusion alterations in normal women at risk of Alzheimer's disease
    Charles D Smith
    Department of Neurology, University of Kentucky, Lexington, KY 40536, USA
    Neurobiol Aging 31:1122-31. 2010
    ..These findings demonstrate that specific white matter pathways are altered in normal women at increased risk of AD years before the expected onset of cognitive symptoms...
  18. ncbi request reprint Functional dissociation in frontal and striatal areas for processing of positive and negative reward information
    Xun Liu
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, Kentucky 40536, USA
    J Neurosci 27:4587-97. 2007
    ..These distinct but interactive systems may serve to guide human's reward-seeking behavior...
  19. ncbi request reprint Common and dissociable activation patterns associated with controlled semantic and phonological processing: evidence from FMRI adaptation
    Brian T Gold
    Department of Anatomy and Neurobiology, Chandler Medical Center, University of Kentucky, Lexington, KY, USA
    Cereb Cortex 15:1438-50. 2005
    ....
  20. ncbi request reprint Common prefrontal regions coactivate with dissociable posterior regions during controlled semantic and phonological tasks
    Brian T Gold
    Department of Psychology, Washington University, One Brookings Drive, St Louis, MO 63130, USA
    Neuron 35:803-12. 2002
    ..These findings suggest that LIPC participates in controlled processing across multiple information domains collaborating with dissociable posterior regions depending upon the kind of information retrieved...