LISA GOEHLER

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. ncbi request reprint Vagal immune-to-brain communication: a visceral chemosensory pathway
    L E Goehler
    Department of Psychology, University of Virginia, Charlottesville 22904, USA
    Auton Neurosci 85:49-59. 2000
  2. pmc Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
    Michael Maes
    Maes Clinics TRIA, Piyavate Hospital, 998 Rimklongsamsen Road, Bangkok 10310, Thailand
    BMC Med 10:66. 2012
  3. pmc Infection-induced viscerosensory signals from the gut enhance anxiety: implications for psychoneuroimmunology
    Lisa E Goehler
    Department of Psychology, University of Virginia, Charlottesville, VA 22904 4400, USA
    Brain Behav Immun 21:721-6. 2007
  4. ncbi request reprint Vagal complexity: substrate for body-mind connections?
    Lisa E Goehler
    Department of Psychology University of Virginia, Charlottesville VA 22904, USA
    Bratisl Lek Listy 107:275-6. 2006
  5. ncbi request reprint Neural-immune interface in the rat area postrema
    L E Goehler
    Program in Sensory and Systems Neuroscience, Department of Psychology and Neuroscience Graduate Program, University of Virginia, Charlottesville, VA 22904, USA
    Neuroscience 140:1415-34. 2006
  6. ncbi request reprint Activation in vagal afferents and central autonomic pathways: early responses to intestinal infection with Campylobacter jejuni
    Lisa E Goehler
    Department of Psychology, University of Virginia, Charlottesville, VA 22904, United States
    Brain Behav Immun 19:334-44. 2005
  7. ncbi request reprint Staphylococcal enterotoxin B induces fever, brain c-Fos expression, and serum corticosterone in rats
    L E Goehler
    Department of Psychology, University of Virginia, Charlottesville, Virginia 22904, USA
    Am J Physiol Regul Integr Comp Physiol 280:R1434-9. 2001
  8. pmc How does immune challenge inhibit ingestion of palatable food? Evidence that systemic lipopolysaccharide treatment modulates key nodal points of feeding neurocircuitry
    Su Mi Park
    Department of Psychology, Laboratory of Neuroimmunology and Behavior, University of Virginia, 102 Gilmer Hall, PO Box 400400, Charlottesville, VA 22904, USA
    Brain Behav Immun 22:1160-72. 2008
  9. pmc Campylobacter jejuni infection increases anxiety-like behavior in the holeboard: possible anatomical substrates for viscerosensory modulation of exploratory behavior
    Lisa E Goehler
    Department of Psychology, University of Virginia, Charlottesville, VA 22904, USA
    Brain Behav Immun 22:354-66. 2008
  10. ncbi request reprint Reversible inactivation of the dorsal vagal complex blocks lipopolysaccharide-induced social withdrawal and c-Fos expression in central autonomic nuclei
    Françoise A Marvel
    Department of Psychology and Neuroscience Graduate Program, University of Virginia, Charlottesville, VA 22904, USA
    Brain Behav Immun 18:123-34. 2004

Research Grants

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Vagal immune-to-brain communication: a visceral chemosensory pathway
    L E Goehler
    Department of Psychology, University of Virginia, Charlottesville 22904, USA
    Auton Neurosci 85:49-59. 2000
    ..In this way, immunosensory systems represent highly organized and coherent pathways for activating host defense against infection...
  2. pmc Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
    Michael Maes
    Maes Clinics TRIA, Piyavate Hospital, 998 Rimklongsamsen Road, Bangkok 10310, Thailand
    BMC Med 10:66. 2012
    ....
  3. pmc Infection-induced viscerosensory signals from the gut enhance anxiety: implications for psychoneuroimmunology
    Lisa E Goehler
    Department of Psychology, University of Virginia, Charlottesville, VA 22904 4400, USA
    Brain Behav Immun 21:721-6. 2007
    ....
  4. ncbi request reprint Vagal complexity: substrate for body-mind connections?
    Lisa E Goehler
    Department of Psychology University of Virginia, Charlottesville VA 22904, USA
    Bratisl Lek Listy 107:275-6. 2006
  5. ncbi request reprint Neural-immune interface in the rat area postrema
    L E Goehler
    Program in Sensory and Systems Neuroscience, Department of Psychology and Neuroscience Graduate Program, University of Virginia, Charlottesville, VA 22904, USA
    Neuroscience 140:1415-34. 2006
    ....
  6. ncbi request reprint Activation in vagal afferents and central autonomic pathways: early responses to intestinal infection with Campylobacter jejuni
    Lisa E Goehler
    Department of Psychology, University of Virginia, Charlottesville, VA 22904, United States
    Brain Behav Immun 19:334-44. 2005
    ..These findings provide evidence that peripheral sensory neurons contribute an early signal to the brain regarding potential pathogens...
  7. ncbi request reprint Staphylococcal enterotoxin B induces fever, brain c-Fos expression, and serum corticosterone in rats
    L E Goehler
    Department of Psychology, University of Virginia, Charlottesville, Virginia 22904, USA
    Am J Physiol Regul Integr Comp Physiol 280:R1434-9. 2001
    ..These results support the idea that T cell-dependent immune stimuli activate brain pathways mediating host-defense responses such as fever and neuroendocrine changes...
  8. pmc How does immune challenge inhibit ingestion of palatable food? Evidence that systemic lipopolysaccharide treatment modulates key nodal points of feeding neurocircuitry
    Su Mi Park
    Department of Psychology, Laboratory of Neuroimmunology and Behavior, University of Virginia, 102 Gilmer Hall, PO Box 400400, Charlottesville, VA 22904, USA
    Brain Behav Immun 22:1160-72. 2008
    ....
  9. pmc Campylobacter jejuni infection increases anxiety-like behavior in the holeboard: possible anatomical substrates for viscerosensory modulation of exploratory behavior
    Lisa E Goehler
    Department of Psychology, University of Virginia, Charlottesville, VA 22904, USA
    Brain Behav Immun 22:354-66. 2008
    ....
  10. ncbi request reprint Reversible inactivation of the dorsal vagal complex blocks lipopolysaccharide-induced social withdrawal and c-Fos expression in central autonomic nuclei
    Françoise A Marvel
    Department of Psychology and Neuroscience Graduate Program, University of Virginia, Charlottesville, VA 22904, USA
    Brain Behav Immun 18:123-34. 2004
    ..Collectively, these findings support the idea that the DVC acts as an immune-behavior interface between the peripheral stimuli and brain areas involved in modulating social behavior...
  11. ncbi request reprint Organization of immune-responsive medullary projections to the bed nucleus of the stria terminalis, central amygdala, and paraventricular nucleus of the hypothalamus: evidence for parallel viscerosensory pathways in the rat brain
    Ronald P A Gaykema
    Program in Sensory and Systems Neuroscience, Department of Psychology, P O Box 400400, University of Virginia, Charlottesville, VA 22904 4400, USA
    Brain Res 1130:130-45. 2007
    ....
  12. ncbi request reprint Enhanced neuronal activation in central autonomic network nuclei in aged mice following acute peripheral immune challenge
    Ronald P A Gaykema
    Program in Sensory and Systems Neuroscience, Department of Psychology, University of Virginia, Charlottesville, VA 22904, USA
    Auton Neurosci 131:137-42. 2007
    ....
  13. pmc Cranial electrical stimulation: potential use in reducing sleep and mood disturbances in persons with dementia and their family caregivers
    Karen M Rose
    School of Nursing, University of Virginia, Charlottesville, VA 22908, USA
    Fam Community Health 31:240-6. 2008
    ..The proposed mechanism of action and studies that support cranial electrical stimulation as a modality to reduce distressing symptoms are reviewed. Directions for research are proposed...
  14. ncbi request reprint Brain response to cecal infection with Campylobacter jejuni: analysis with Fos immunohistochemistry
    Ronald P A Gaykema
    Department of Psychology and Neuroscience Graduate Program, University of Virginia, Charlottesville, VA 22904, USA
    Brain Behav Immun 18:238-45. 2004
    ..jejuni in the gut is indeed relayed to the visceral sensory structures in the brain. The brain responses observed could contribute to changes in behavior observed after infection...
  15. pmc Lipopolysaccharide challenge-induced suppression of Fos in hypothalamic orexin neurons: their potential role in sickness behavior
    Ronald P A Gaykema
    Laboratory of Neuroimmunology and Behavior, Center for the Study of Complementary and Alternative Therapies, University of Virginia, School of Nursing, Charlottesville VA 22908 0782, USA
    Brain Behav Immun 23:926-30. 2009
    ....
  16. pmc Top-down and bottom-up mechanisms in mind-body medicine: development of an integrative framework for psychophysiological research
    Ann Gill Taylor
    Center for the Study of Complementary and Alternative Therapies, School of Nursing, University of Virginia, Charlottesville, VA, USA
    Explore (NY) 6:29-41. 2010
    ..Finally, we review current neuroimaging and psychophysiological research from diverse areas of mind-body medicine that supports the framework as a basis for future research on the specific biobehavioral mechanisms of mind-body therapies...
  17. pmc Pathogen-induced heart rate changes associated with cholinergic nervous system activation
    Karen D Fairchild
    Dept of Pediatrics, University of Virginia Health System, Hospital Dr, Charlottesville, VA 22908, USA
    Am J Physiol Regul Integr Comp Physiol 300:R330-9. 2011
    ..Pathogen sensing and signaling via the vagus nerve, and the desensitization of this response, may account for periods of both increased and decreased heart rate variability in sepsis...
  18. ncbi request reprint Recommended housing conditions and test procedures can interact to obscure a significant experimental effect
    Mark Lyte
    Minneapolis Medical Research Foundation, Minneapolis, Minnesota, USA
    Behav Res Methods 37:651-6. 2005
    ....
  19. ncbi request reprint Induction of anxiety-like behavior in mice during the initial stages of infection with the agent of murine colonic hyperplasia Citrobacter rodentium
    Mark Lyte
    Department of Pharmacy Practice, School of Pharmacy, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
    Physiol Behav 89:350-7. 2006
    ..The results of the present study demonstrate that infection with C. rodentium can induce anxiety-like symptoms that are likely mediated via vagal sensory neurons...

Research Grants5

  1. Neural and Immune Cell Interactions: Two of a Kind
    LISA GOEHLER; Fiscal Year: 2002
    ..Finally, the interactions between immune and neural cells may well be bi-directional, providing a novel mechanism by which neural activity can modulate immune cell functions. ..
  2. Neurocircuitry of Illness Induced Behavioral Depression
    LISA GOEHLER; Fiscal Year: 2009
    ....