Research Topics
Genomes and GenesSpecies | Rodney C P GoSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Detail Information
Publications
Comparison of measures of marker informativeness for ancestry and admixture mappingLili Ding
Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA
BMC Genomics 12:622. 2011....- Is cumulative frequency of mitochondrial DNA variants a biomarker for colorectal tumor progression?Felix O Aikhionbare
Department of Medicine, Morehouse School of Medicine, Atlanta, GA 30310, USA
Mol Cancer 3:30. 2004..To the best of our knowledge, this is the first report to show an increased prevalence of mitochondrial gene variants in CRC tumorigenesis... - Ancestry reported by white adults with cutaneous melanoma and control subjects in central AlabamaRonald T Acton
Immunogenetics Program and Departments of Microbiology, University of Alabama at Birmingham, Alabama, USA
BMC Cancer 4:47. 2004..We sought to evaluate the hypothesis that the high incidence of cutaneous melanoma in white persons in central Alabama is associated with a predominance of Irish and Scots descent... 
Prevalence and risk factors of microalbuminuria in a cohort of African-American women with gestational diabetesR C Go
Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA
Diabetes Care 24:1764-9. 2001....- Neuregulin-1 polymorphism in late onset Alzheimer's disease families with psychosesRodney C P Go
University of Alabama at Birmingham, Birmingham, AL 35294, USA
Am J Med Genet B Neuropsychiatr Genet 139:28-32. 2005..Our results suggest that NRG1 plays a role in increasing the genetic risk to positive symptoms of psychosis in a proportion of LOAD families... - A genomic scan for age at onset of Alzheimer's disease in 437 families from the NIMH Genetic InitiativeM Ryan Dickson
Department of Epidemiology and International Health, The University of Alabama at Birmingham, Birmingham, Alabama 35294 0001, USA
Am J Med Genet B Neuropsychiatr Genet 147:784-92. 2008..Results replicate previous findings, but identify additional suggestive peaks indicating the genetics of AAO in AD is complex with many chromosomal regions potentially containing modifying genes... - Genetic association of neurotrophic tyrosine kinase receptor type 2 (NTRK2) With Alzheimer's diseaseZuomin Chen
Department of Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, Alabama 35294, USA
Am J Med Genet B Neuropsychiatr Genet 147:363-9. 2008..These SNPs are located in areas of the gene containing sequences that could be involved in alternative splicing and/or regulation of NTRK2. Our results suggest that NTRK2 may be a genetic susceptibility gene contributing to AD pathology... - HLA haplotype A*03-B*07 in hemochromatosis probands with HFE C282Y homozygosity: frequency disparity in men and women and lack of association with severity of iron overloadJames C Barton
Southern Iron Disorders Center, Birmingham, AL 35209, USA
Blood Cells Mol Dis 34:38-47. 2005.... - Candidate gene discovery procedure after follow-up confirmatory analyses of candidate regions of interests for Alzheimer's disease in the NIMH sibling datasetTesfaye M Baye
Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Dis Markers 24:293-309. 2008..alzgene.org)... - Follow-up mapping supports the evidence for linkage in the candidate region at 9q22 in the NIMH Alzheimer's disease Genetics Initiative cohortRodney T Perry
Department of Epidemiology and International Health, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
Am J Med Genet B Neuropsychiatr Genet 144:220-7. 2007..In an effort to pinpoint this putative AD susceptibility gene, we have begun to analyze SNPs in other candidate genes in and around this narrowed region to test for additional associations to AD... - Effects of chronic stress and interleukin-10 gene polymorphisms on antibody response to tetanus vaccine in family caregivers of patients with Alzheimer's diseaseJian Li
Department of Epidemiology and International Health, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
Psychosom Med 69:551-9. 2007..To assess the effects of psychological stress on the antibody response to tetanus vaccine adjusting for cytokine gene polymorphisms and other nongenetic factors in caregivers of patients with Alzheimer's disease (AD)... - COGA phenotypes and linkages on chromosome 2Howard W Wiener
Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
BMC Genet 6:S125. 2005..A region on chromosome 2 at 250 cM was found to be linked to both of these derived phenotypes. Further examination of the SNPs in this region identified several haplotypes strongly associated with these derived phenotypes... - Hemoglobin binding to A beta and HBG2 SNP association suggest a role in Alzheimer's diseaseRodney T Perry
Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
Neurobiol Aging 29:185-93. 2008..010) and >65 years (p=0.013), and families not homozygous for the APOE4 allele (p=0.041). We hypothesize that Hb F may be less toxic than adult Hb in its interaction with A beta and may protect against the development of AD... - SSCP analysis and sequencing of the human prion protein gene (PRNP) detects two different 24 bp deletions in an atypical Alzheimer's disease familyR T Perry
University of Alabama at Birmingham, USA
Am J Med Genet 60:12-8. 1995..It does not appear that mutations at the PRNP locus are frequently associated with AD in this population... - HFE mutations in African-American women with non-insulin-dependent diabetes mellitusR T Acton
Department of Microbiology, University of Alabama at Birmingham, USA
Ethn Dis 11:578-84. 2001.... - Susceptibility locus for IgA deficiency and common variable immunodeficiency in the HLA-DR3, -B8, -A1 haplotypesH W Schroeder
Department of Medicine, Institute, University of Alabama at Birmingham, Birmingham, Alabama 35294 3300, USA
Mol Med 4:72-86. 1998..In a search for the gene(s) in the major histocompatibility complex (MHC) that predispose to IgAD/CVID, we analyzed the extended MHC haplotypes present in a large family with 8 affected members... - Associations of MHC genes with levels of caries-inducing organisms and caries severity in African-American womenR T Acton
Department of Microbiology, Schools of Dentistry, Medicine and Public Health, University of Alabama at Birmingham 35294 4400, USA
Hum Immunol 60:984-9. 1999..These results support an hypothesis of an association between host HLA class II and TNFa genetic profile and colonization of S. mutans, L. casei, and L. acidophilus thought to be pathogens involved in the etiology of dental caries... - Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controlsR T Perry
Department of Epidemiology and International Health, University of Alabama at Birmingham, 35294, USA
Am J Med Genet 105:332-42. 2001..In addition, TNF appears to have some modifying effect in AD, primarily on age of onset, or it could be in linkage disequilibrium with a modifier locus nearby... - The role of TNF and its receptors in Alzheimer's diseaseR T Perry
Department of Epidemiology and International Health, University of Alabama at Birmingham, 35294, USA
Neurobiol Aging 22:873-83. 2001..We found no significant association of three polymorphisms in the TNFR1 gene to AD. These results provide further evidence for the involvement of TNF in the pathogenesis of AD... - Project among African-Americans to explore risks for schizophrenia (PAARTNERS): recruitment and assessment methodsMuktar H Aliyu
Department of Psychiatry, University of Alabama at Birmingham, Birmingham, AL 35294 2041, and Duke University Medical Center John Umstead Hospital, Butner, NC, United States
Schizophr Res 87:32-44. 2006..This novel integration of diagnostic, neurocognitive and genetic data will also generate valuable information for future phenotypic and genetic studies of schizophrenia... - Genetics and cardiovascular diseaseRonald T Acton
Department of Microbiology, Immunogenetics Program, University of Alabama at Birmingham, Alabama 35294 0005, USA
Ethn Dis 14:S2-8-16. 2004.... - Increased frequency of HLA-B44 in recurrent sinopulmonary infections (RESPI)Douglas T Johnston
University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham, AL 35294 3300, USA
Clin Immunol 119:346-50. 2006..0001). Inheritance of HLA-B44 may yield susceptibility to recurrent sinopulmonary infection even in the presence of normal serum immunoglobulin levels... - Genetic epidemiologic methods to screen for matrilineal inheritance in mitochondrial disordersF Mili
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Genet Epidemiol 13:605-14. 1996..To illustrate our epidemiologic method, we apply our screening method to pedigrees of two disorders which have been proposed to have a mitochondrial DNA component to their inheritance... - Further evidence of a maternal parent-of-origin effect on chromosome 10 in late-onset Alzheimer's diseaseSusan Spear Bassett
Department of Psychiatry, Johns Hopkins University, Baltimore, Maryland, USA
Am J Med Genet B Neuropsychiatr Genet 141:537-40. 2006.... - African-American community attitudes and perceptions toward schizophrenia and medical research: an exploratory studyLynnae A Hamilton
Fielding Graduate University, Santa Barbara, CA, USA
J Natl Med Assoc 98:18-27. 2006..CONCLUSION: The provision of accurate information through trusted community sources and open dialogue will help to dispel myths, correct faulty assumptions and increase African-American participation in schizophrenia research... - Association between apolipoprotein E genotype and Alzheimer disease in African American subjectsNeill R Graff-Radford
Genetics Program L 320, Boston University School of Medicine, 715 Albany St, Boston, MA 02118, USA
Arch Neurol 59:594-600. 2002..The association between Alzheimer disease (AD) and genotypes at the apolipoprotein E (APOE) locus has been confirmed in numerous populations worldwide, but appears to be inconsistent in African American subjects... - Results of a high-resolution genome screen of 437 Alzheimer's disease familiesDeborah Blacker
Massachusetts General Hospital, Charlestown, MA, USA
Hum Mol Genet 12:23-32. 2003..Although some of these will surely prove to be false positives, these linkage signals should provide a valuable framework for future studies aimed at identifying additional susceptibility genes for late-onset AD... - Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulinAleister J Saunders
Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
Hum Mol Genet 12:2765-76. 2003..However, the negative case - control studies suggest that any underlying pathogenic polymorphisms have a modest effect, and may operate primarily among individuals with a family history of AD...