M Gnanasekar

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. pmc HMGB1: A Promising Therapeutic Target for Prostate Cancer
    Munirathinam Gnanasekar
    Department of Biomedical Sciences, College of Medicine, University of Illinois, 1601 Parkview Avenue, Rockford, IL 61107, USA
    Prostate Cancer 2013:157103. 2013
  2. pmc Vitamin k2, a naturally occurring menaquinone, exerts therapeutic effects on both hormone-dependent and hormone-independent prostate cancer cells
    Abhilash Samykutty
    Department of Biomedical Sciences, University of Illinois, Rockford, IL 61107, USA
    Evid Based Complement Alternat Med 2013:287358. 2013
  3. pmc Possible role of Toxoplasma gondii in brain cancer through modulation of host microRNAs
    Sivasakthivel Thirugnanam
    Department of Biomedical Sciences, University of Illinois, College of Medicine, 1601 Parkview Ave, Rockford, IL, 61107, USA
    Infect Agent Cancer 8:8. 2013
  4. ncbi request reprint Short hairpin RNA (shRNA) constructs targeting high mobility group box-1 (HMGB1) expression leads to inhibition of prostate cancer cell survival and apoptosis
    Munirathinam Gnanasekar
    Department of Biomedical Sciences, University of Illinois, College of Medicine, Rockford, IL 61107, USA
    Int J Oncol 34:425-31. 2009
  5. ncbi request reprint Gene silencing of translationally controlled tumor protein (TCTP) by siRNA inhibits cell growth and induces apoptosis of human prostate cancer cells
    Munirathinam Gnanasekar
    Department of Biomedical Sciences, University of Illinois, College of Medicine, Rockford, IL 61107, USA
    Int J Oncol 34:1241-6. 2009
  6. doi request reprint T-oligo induces apoptosis in advanced prostate cancer cells
    Munirathinam Gnanasekar
    Department of Biomedical Sciences, University of Illinois, College of Medicine, 1601 Parkview Avenue, Rockford, IL 61107, USA
    Oligonucleotides 19:287-92. 2009
  7. ncbi request reprint Identification of sex hormone binding globulin-interacting proteins in the brain using phage display screening
    M Gnanasekar
    Department of Biomedical Sciences, University of Illinois College of Medicine, Rockford, IL 61107, USA
    Int J Mol Med 24:421-6. 2009
  8. ncbi request reprint Molecular characterization of a calcium binding translationally controlled tumor protein homologue from the filarial parasites Brugia malayi and Wuchereria bancrofti
    M Gnanasekar
    Department of Biomedical Sciences, University of Illinois College of Medicine, 1601 Parkview Avenue, Rockford, IL 61107, USA
    Mol Biochem Parasitol 121:107-18. 2002

Collaborators

Detail Information

Publications9

  1. pmc HMGB1: A Promising Therapeutic Target for Prostate Cancer
    Munirathinam Gnanasekar
    Department of Biomedical Sciences, College of Medicine, University of Illinois, 1601 Parkview Avenue, Rockford, IL 61107, USA
    Prostate Cancer 2013:157103. 2013
    ..This paper focuses on the role of HMGB1 in prostate cancer development and highlights the potential of HMGB1 to serve as a key target for prostate cancer treatment...
  2. pmc Vitamin k2, a naturally occurring menaquinone, exerts therapeutic effects on both hormone-dependent and hormone-independent prostate cancer cells
    Abhilash Samykutty
    Department of Biomedical Sciences, University of Illinois, Rockford, IL 61107, USA
    Evid Based Complement Alternat Med 2013:287358. 2013
    ..Overall, our results suggest that VK2 may be a potential therapeutic agent in the treatment of prostate cancer. ..
  3. pmc Possible role of Toxoplasma gondii in brain cancer through modulation of host microRNAs
    Sivasakthivel Thirugnanam
    Department of Biomedical Sciences, University of Illinois, College of Medicine, 1601 Parkview Ave, Rockford, IL, 61107, USA
    Infect Agent Cancer 8:8. 2013
    ..However, molecular events involved in Toxoplasma induced brain cancers are not well understood...
  4. ncbi request reprint Short hairpin RNA (shRNA) constructs targeting high mobility group box-1 (HMGB1) expression leads to inhibition of prostate cancer cell survival and apoptosis
    Munirathinam Gnanasekar
    Department of Biomedical Sciences, University of Illinois, College of Medicine, Rockford, IL 61107, USA
    Int J Oncol 34:425-31. 2009
    ..Our findings may have some potential therapeutic relevance for treating prostate cancer...
  5. ncbi request reprint Gene silencing of translationally controlled tumor protein (TCTP) by siRNA inhibits cell growth and induces apoptosis of human prostate cancer cells
    Munirathinam Gnanasekar
    Department of Biomedical Sciences, University of Illinois, College of Medicine, Rockford, IL 61107, USA
    Int J Oncol 34:1241-6. 2009
    ..Results presented herein suggest a potential therapeutic application for prostate cancer by targeting TCTP gene using an siRNA approach...
  6. doi request reprint T-oligo induces apoptosis in advanced prostate cancer cells
    Munirathinam Gnanasekar
    Department of Biomedical Sciences, University of Illinois, College of Medicine, 1601 Parkview Avenue, Rockford, IL 61107, USA
    Oligonucleotides 19:287-92. 2009
    ..Therefore, our results are encouraging for further investigation in the potential application of T-oligo as a novel therapeutic approach for prostate cancer, especially the androgen-independent...
  7. ncbi request reprint Identification of sex hormone binding globulin-interacting proteins in the brain using phage display screening
    M Gnanasekar
    Department of Biomedical Sciences, University of Illinois College of Medicine, Rockford, IL 61107, USA
    Int J Mol Med 24:421-6. 2009
    ..Further studies will determine if the interactions of SHBG with these proteins have any role in the internalization and cell signaling events or whether they contribute to steroid delivery to specific cells...
  8. ncbi request reprint Molecular characterization of a calcium binding translationally controlled tumor protein homologue from the filarial parasites Brugia malayi and Wuchereria bancrofti
    M Gnanasekar
    Department of Biomedical Sciences, University of Illinois College of Medicine, 1601 Parkview Avenue, Rockford, IL 61107, USA
    Mol Biochem Parasitol 121:107-18. 2002
    ....