Stephen L Gluck

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Acid sensing in renal epithelial cells
    Stephen L Gluck
    Division of Nephrology, UCSF, 513 Parnassus Avenue, Box 0532, San Francisco, California 94143 0532, USA
    J Clin Invest 114:1696-9. 2004
  2. pmc Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells
    Yuri Y Sautin
    Department of Medicine, Division of Nephrology, Box 100224, University of Florida, 1600 SW Archer Rd, Gainesville, FL 32610 0224, USA
    Mol Cell Biol 25:575-89. 2005
  3. ncbi request reprint Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump
    Ming Lu
    Department of Medicine, University of California School of Medicine, San Francisco, California 94143 0532, USA
    J Biol Chem 282:24495-503. 2007
  4. ncbi request reprint The glycolytic enzyme aldolase mediates assembly, expression, and activity of vacuolar H+-ATPase
    Ming Lu
    Department of Medicine, University of California, San Francisco, California 94143, USA
    J Biol Chem 279:8732-9. 2004
  5. ncbi request reprint The amino-terminal domain of the E subunit of vacuolar H(+)-ATPase (V-ATPase) interacts with the H subunit and is required for V-ATPase function
    Ming Lu
    Department of Medicine University of Florida College of Medicine, Gainesville, Florida 32610, USA
    J Biol Chem 277:38409-15. 2002
  6. ncbi request reprint Vacuolar H+-ATPase binding to microfilaments: regulation in response to phosphatidylinositol 3-kinase activity and detailed characterization of the actin-binding site in subunit B
    Shih Hua Chen
    Department of Orthodontics, University of Florida College of Dentistry, Gainesville, Florida 32610, USA
    J Biol Chem 279:7988-98. 2004
  7. pmc IFN-gamma regulation of vacuolar pH, cathepsin D processing and autophagy in mammary epithelial cells
    Zhila Khalkhali-Ellis
    Children s Memorial Research Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60614 3394, USA
    J Cell Biochem 105:208-18. 2008

Detail Information

Publications7

  1. pmc Acid sensing in renal epithelial cells
    Stephen L Gluck
    Division of Nephrology, UCSF, 513 Parnassus Avenue, Box 0532, San Francisco, California 94143 0532, USA
    J Clin Invest 114:1696-9. 2004
    ..The findings implicate a broader role for Pyk2 in acid-base homeostasis in bone and other tissues beyond the kidney...
  2. pmc Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells
    Yuri Y Sautin
    Department of Medicine, Division of Nephrology, Box 100224, University of Florida, 1600 SW Archer Rd, Gainesville, FL 32610 0224, USA
    Mol Cell Biol 25:575-89. 2005
    ....
  3. ncbi request reprint Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump
    Ming Lu
    Department of Medicine, University of California School of Medicine, San Francisco, California 94143 0532, USA
    J Biol Chem 282:24495-503. 2007
    ..Taken together, these findings strongly suggest an important role for physical association between aldolase and V-ATPase in the regulation of the proton pump...
  4. ncbi request reprint The glycolytic enzyme aldolase mediates assembly, expression, and activity of vacuolar H+-ATPase
    Ming Lu
    Department of Medicine, University of California, San Francisco, California 94143, USA
    J Biol Chem 279:8732-9. 2004
    ..Taken together, these findings provide functional evidence that the ATP-generating glycolytic pathway is directly coupled to the ATP-hydrolyzing proton pump through physical interaction between aldolase and V-ATPase...
  5. ncbi request reprint The amino-terminal domain of the E subunit of vacuolar H(+)-ATPase (V-ATPase) interacts with the H subunit and is required for V-ATPase function
    Ming Lu
    Department of Medicine University of Florida College of Medicine, Gainesville, Florida 32610, USA
    J Biol Chem 277:38409-15. 2002
    ..Our data demonstrate the physiological significance of the interaction between the E and H subunits of V-ATPase and extend previous studies on the arrangement of subunits on the peripheral stalk of V-ATPase...
  6. ncbi request reprint Vacuolar H+-ATPase binding to microfilaments: regulation in response to phosphatidylinositol 3-kinase activity and detailed characterization of the actin-binding site in subunit B
    Shih Hua Chen
    Department of Orthodontics, University of Florida College of Dentistry, Gainesville, Florida 32610, USA
    J Biol Chem 279:7988-98. 2004
    ..This response was fully reversible. The actin binding activities of the B subunits of V-ATPase required 11-amino acid actin-binding motifs that are similar in sequence to the actin-binding site of mammalian profilin I...
  7. pmc IFN-gamma regulation of vacuolar pH, cathepsin D processing and autophagy in mammary epithelial cells
    Zhila Khalkhali-Ellis
    Children s Memorial Research Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60614 3394, USA
    J Cell Biochem 105:208-18. 2008
    ..However, Maspin transfection of breast cancer cells partially sensitizes the cells to IFN-gamma's effect, thus providing new therapeutic implications...