Research Topics
| O A GlennSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
DTI-based three-dimensional tractography detects differences in the pyramidal tracts of infants and children with congenital hemiparesisOrit A Glenn
Department of Radiology, University of California San Francisco, San Francisco, California 94143, USA
J Magn Reson Imaging 18:641-8. 2003..To test the hypothesis that there is greater asymmetry in diffusion properties between right and left pyramidal tracts in patients with congenital hemiparesis than in patients with normal motor function...- Diffusion tensor MR imaging tractography of the pyramidal tracts correlates with clinical motor function in children with congenital hemiparesisO A Glenn
Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
AJNR Am J Neuroradiol 28:1796-802. 2007..We hypothesized that the asymmetry correlates with the severity of hemiparesis and that diffusion metrics would be abnormal in the affected tracts and normal in the unaffected tracts... - Fetal cerebellar hemorrhage in parvovirus-associated non-immune hydrops fetalisOrit A Glenn
Department of Radiology, University of California, San Francisco, San Francisco, CA 94143 0628, USA
J Matern Fetal Neonatal Med 20:769-72. 2007..To our knowledge, this is the first report of fetal cerebellar hemorrhage in the setting of parvovirus-associated hydrops fetalis, and may be the result of cerebrovascular changes both during and after the transfusion... 
Diffusion-weighted imaging in fetuses with unilateral cortical malformations and callosal agenesisO A Glenn
Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA
AJNR Am J Neuroradiol 31:1100-2. 2010..Our findings suggest that there are structural differences in the developing white matter underlying areas of cortical malformation...- Magnetic resonance imaging of the fetal brain and spine: an increasingly important tool in prenatal diagnosis: part 2O A Glenn
University of California, San Francisco, Department of Radiology, Box 0628, 505 Parnassus Ave, L 358, San Francisco, CA 94143 0628, USA
AJNR Am J Neuroradiol 27:1807-14. 2006..In this second part, we focus on additional clinical applications of fetal MR imaging, including suspected abnormalities of the corpus callosum, malformations of cortical development, and spine abnormalities... - Magnetic resonance imaging of the fetal brain and spine: an increasingly important tool in prenatal diagnosis, part 1O A Glenn
Department of Radiology, University of California, San Francisco, San Francisco, CA 94143, USA
AJNR Am J Neuroradiol 27:1604-11. 2006..The second part focuses on additional clinical applications of fetal MR imaging, including suspected abnormalities of the corpus callosum, malformations of cortical development, and spine abnormalities... 
MR imaging of the fetal brainOrit A Glenn
Department of Radiology, Neuroradiology Section, University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA 94143, USA
Pediatr Radiol 40:68-81. 2010..This paper will briefly discuss the common clinical conditions imaged by fetal MRI as well as recent advances in fetal MRI research...- Fetal central nervous system MR imagingOrit A Glenn
Neuroradiology Section, Department of Radiology, University of California at San Francisco, CA 94143 0628, USA
Neuroimaging Clin N Am 16:1-17, vii. 2006..Moreover, fetal MR imaging offers the promise of contributing to our understanding of normal as well as abnormal brain development with continued advances in MR imaging techniques, such as diffusion-weighted and parallel imaging... - Fetal magnetic resonance imaging in the evaluation of fetuses referred for sonographically suspected abnormalities of the corpus callosumOrit A Glenn
Department of Radiology, Neuroradiology Section, University of California, San Francisco, CA 94143 0628, USA
J Ultrasound Med 24:791-804. 2005..However, its utility in specific brain disorders has not been well investigated. We hypothesized that fetal MRI can better assess the integrity of the brain in cases with sonographically suspected callosal abnormalities... - Normal development of the fetal brain by MRIOrit A Glenn
Department of Radiology, Neuroradiology Section, University of California, San Francisco, CA 94143, USA
Semin Perinatol 33:208-19. 2009..An understanding of normal fetal brain development is essential to correctly identifying developmental abnormalities... - MRI of the fetal central nervous system and bodyOrit A Glenn
Department of Radiology, University of California, San Francisco, CA 94143, USA
Clin Perinatol 36:273-300, viii. 2009..Because fetal MRI involves many disciplines, the future of fetal MR will best be achieved through collaborative efforts... - Prenatal diagnosis of polymicrogyria by fetal magnetic resonance imaging in monochorionic cotwin deathOrit A Glenn
Department of Radiology, University of California, San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143-0628, USA
J Ultrasound Med 24:711-6. 2005 - Diffusion tensor imaging of the pyramidal tracts in infants with motor dysfunctionN A Ludeman
Department of Radiology, University of California San Francisco, San Francisco, CA 94143 0628, USA
Neurology 71:1676-82. 2008..To determine if diffusion tensor imaging (DTI) metrics of the pyramidal tracts correlate with motor outcome in infants presenting with motor dysfunction... - Diffusion-weighted imaging in fetuses with severe congenital heart defectsJ I Berman
Department of Radiology, University of California, San Francisco, USA
AJNR Am J Neuroradiol 32:E21-2. 2011..Diffusivity in the periatrial WM and thalamus was higher for the fetuses with CHD compared with controls. These observations support the finding of abnormal in utero brain development in fetuses with CHD... - 3D global and regional patterns of human fetal subplate growth determined in uteroJ Corbett-Detig
Biomedical Image Computing Group, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143 0628, USA
Brain Struct Funct 215:255-63. 2011..During this period, the thickest region was the developing somatosensory/motor cortex. The subplate growth patterns reported here may be used as a baseline for comparison to abnormal fetal brain development... - Agenesis of the corpus callosum: an MR imaging analysis of associated abnormalities in the fetusP H Tang
Department of Radiology, University of California, San Francisco, San Francisco, Calif, USA
AJNR Am J Neuroradiol 30:257-63. 2009..This study will assess those anomalies and compare them with postnatal cohorts of ACC, to identify associated fetal brain abnormalities that may give insight into etiology and outcome... - Normative apparent diffusion coefficient values in the developing fetal brainM M Schneider
Departments of Radiology and Biomedical Imaging, Department of Pediatrics, University of California, San Francisco, CA 94143 0628, USA
AJNR Am J Neuroradiol 30:1799-803. 2009.... - MR imaging, MR spectroscopy, and diffusion tensor imaging of sequential studies in neonates with encephalopathyA J Barkovich
Department of Radiology, University of California at San Francisco, San Francisco, Calif 94143-0628, USA
AJNR Am J Neuroradiol 27:533-47. 2006..Awareness of these evolving patterns is essential if studies are performed and interpreted during this critical period of time... - Intracranial magnetic resonance imaging findings in the surviving fetus after spontaneous monochorionic cotwin demiseAngie C Jelin
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, School of Medicine, San Francisco, CA, USA
Am J Obstet Gynecol 199:398.e1-5. 2008..This study was undertaken to evaluate intracranial magnetic resonance imaging abnormalities in the surviving fetus after a cotwin demise... - Atlas-based segmentation of the germinal matrix from in utero clinical MRI of the fetal brainPiotr A Habas
Biomedical Image Computing Group, University of California, San Francisco, San Francisco, CA 94143, USA
Med Image Comput Comput Assist Interv 11:351-8. 2008..5-22.5 weeks. We also include a partial validation of the approach using manual tracing of the germinal matrix at different gestational ages... - Columns of the fornix, not to be mistaken for the cavum septi pellucidi on prenatal sonographyPeter W Callen
Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
J Ultrasound Med 27:25-31. 2008..We have noted that another anatomic structure, the columns of the fornix, can be mistaken for the CSP and result in the missed diagnosis of agenesis of the corpus callosum... - JC virus granule cell neuronopathy in a child with CD40 ligand deficiencyJonathan H Hecht
Department of Neurology, University of California, San Francisco, San Francisco, California 94143 0137, USA
Pediatr Neurol 36:186-9. 2007..JC virus infection should be considered in the differential diagnosis of ataxia in children with inherited immunodeficiencies... - Atlas-based segmentation of developing tissues in the human brain with quantitative validation in young fetusesPiotr A Habas
Biomedical Image Computing Group, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California 94143, USA
Hum Brain Mapp 31:1348-58. 2010..This work indicates that reliable measures of brain development can be automatically derived from clinical MR imaging and opens up possibility of further 3D volumetric and morphometric studies with multiple fetal subjects... - Noninvasive oxygen partial pressure measurement of human body fluids in vivo using magnetic resonance imagingGreg Zaharchuk
University of California, San Francisco, 505 Parnassus Avenue, San Francisco, California 94143 0628, USA
Acad Radiol 13:1016-24. 2006..The purpose of this study is to develop a noninvasive magnetic resonance imaging method to measure the pO2 of human body fluids... - A spatio-temporal atlas of the human fetal brain with application to tissue segmentationPiotr A Habas
Biomedical Image Computing Group, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143, USA
Med Image Comput Comput Assist Interv 12:289-96. 2009..57 to 24.71 weeks. Results indicate improvement in performance of atlas-based EM segmentation provided by higher order temporal models that capture the variation of tissue occurrence over time... - A spatiotemporal atlas of MR intensity, tissue probability and shape of the fetal brain with application to segmentationPiotr A Habas
Biomedical Image Computing Group, University of California San Francisco, San Francisco, CA 94143, USA
Neuroimage 53:460-70. 2010..57 to 24.71 weeks. Experimental results indicate that quadratic temporal models can correctly capture growth-related changes in the fetal brain anatomy and provide improvement in accuracy of atlas-based tissue segmentation... - Measures for characterizing directionality specific volume changes in TBM of brain growthVidya Rajagopalan
Biomedical Image Computing Group, University of California San Francisco, San Francisco, CA 94143, USA
Med Image Comput Comput Assist Interv 13:339-46. 2010..We illustrate the use of these methods by studying brain developmental patterns in fetuses. Results show that this approach detects early changes local growth that are related to the early stages of sulcal and gyral formation... - Intersection based motion correction of multislice MRI for 3-D in utero fetal brain image formationKio Kim
Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA
IEEE Trans Med Imaging 29:146-58. 2010.... - Vanishing MS T2-bright lesions before puberty: a distinct MRI phenotype?D Chabas
UCSF Regional Pediatric Multiple Sclerosis Center, San Francisco, CA 94117, USA
Neurology 71:1090-3. 2008..Pediatric patients with MS may less often meet MRI diagnostic criteria for adults. Whether initial MRI presentation is distinct in prepubertal patients is unknown... - Diffusion tensor imaging: serial quantitation of white matter tract maturity in premature newbornsSavannah C Partridge
Department of Radiology, University of California, San Francisco, San Francisco, CA 94143, USA
Neuroimage 22:1302-14. 2004..This work contributes to the understanding of normal white matter development in the preterm neonatal brain, an important step toward the use of DTI for the improved evaluation and treatment of white matter injury of prematurity... - Polymicrogyria in a fetus with human parvovirus B19 infection: a case with radiologic-pathologic correlationJ Courtier
Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143 0628, USA
Ultrasound Obstet Gynecol 40:604-6. 2012..This case provides further evidence for brain abnormalities resulting from congenital parvovirus B19 infection, and suggests that fetal neuroimaging with MRI would be of value in suspected cases of congenital parvovirus infection... - Evaluation of femur length during the second and third trimesters in fetuses with myelomeningoceleG Williams
Department of Radiology, University of California San Francisco, San Francisco, CA 94143, USA
Ultrasound Obstet Gynecol 23:148-51. 2004.... - Tractography-based quantitation of diffusion tensor imaging parameters in white matter tracts of preterm newbornsSavannah C Partridge
Department of Radiology, University of California-San Francisco, San Francisco, California 94143-2512, USA
J Magn Reson Imaging 22:467-74. 2005..CONCLUSION: Fiber DTT is feasible in premature newborns, provides more reproducible tract measurements than manual ROI methods, and allows quantitation along the entire tract for more detailed DTI assessment of white matter maturation... - Fetal MRI: a developing technique for the developing patientFergus V Coakley
Department of Radiology, University of California San Francisco, 505 Parnassus Ave, San Francisco, CA 94143-0628, USA
AJR Am J Roentgenol 182:243-52. 2004 - Diagnosis of Chiari III malformation by second trimester fetal MRI with postnatal MRI and CT correlationAlice B Smith
Department of Radiology, University of California, San Francisco, San Francisco, CA, USA
Pediatr Radiol 37:1035-8. 2007..Postnatal MRI and CT confirmed the fetal MRI findings and demonstrate the utility of fetal MRI in the early evaluation of songraphically detected posterior fossa abnormalities... - Prenatal imaging of congenital maxillomandibular fusion: case report and review of the literatureKiarash Vahidi
Department of Radiology, University of California, San Francisco, Box 0628, L-325, 505 Parnassus Ave, San Francisco, CA 94143-0628, USA
J Ultrasound Med 26:381-9. 2007 - Fetal magnetic resonance imaging enhances detection of spinal cord anomalies in patients with sonographically detected bony anomalies of the spineCornelia S von Koch
Department of Neurosurgery, University of California, San Francisco, CA 94143-0628, USA
J Ultrasound Med 24:781-9. 2005..Our findings suggest that fetuses with sonographically diagnosed bony abnormalities of the spine may benefit from further evaluation with fetal MRI... - Registration-based approach for reconstruction of high-resolution in utero fetal MR brain imagesFrancois Rousseau
University Louis Pasteur, LSIIT, Pole API, Bd S Brant, Illikirch, France
Acad Radiol 13:1072-81. 2006.... - Diffusion-weighted imaging of the fetal brain in vivoDong Hyun Kim
School of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea
Magn Reson Med 59:216-20. 2008..The method can be readily implemented in a clinical setting and is especially useful when scanning mothers who cannot tolerate lengthier breath-holds...
Research Grants
- In Utero Brain Development in Fetal VentriculomegalyOrit Glenn; Fiscal Year: 2007..abstract_text> ..