Research Topics
Species | Carey E GleasonSummaryAffiliation: University of Wisconsin Country: USA Publications
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Publications
Using predictors of hormone therapy use to model the healthy user bias: how does healthy user status influence cognitive effects of hormone therapy?Carey E Gleason
Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin Madison, School of Medicine and Public Health, Madison, WI, USA
Menopause 19:524-33. 2012..This study investigated the phenomenon known as the healthy user bias by equating hormone therapy (HT) use (past or current) with healthy user status...
Increased risk for falling associated with subtle cognitive impairment: secondary analysis of a randomized clinical trialCarey E Gleason
Section of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin, Madison, Wisconsin 53705, USA
Dement Geriatr Cogn Disord 27:557-63. 2009..This study sought to clarify the relationship between subtle cognitive impairment, measured with a widely-used, clinic-based assessment, the Mini Mental State Exam (MMSE), and risk for falls...
Neuroprotective effects of female sex steroids in humans: current controversies and future directionsC E Gleason
Wm S Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, USA
Cell Mol Life Sci 62:299-312. 2005..Further, the paper briefly discusses variables that may account for the unexpected findings of WHIMS, and offers suggestions for future research...
Clinical pharmacology and differential cognitive efficacy of estrogen preparationsCarey E Gleason
Department of Medicine, University of Wisconsin Medical School, and Geriatric Research, Education and Clinical Center GRECC, William S Middleton Memorial Veterans Hospital, Madison, WI 53705, USA
Ann N Y Acad Sci 1052:93-115. 2005....
Hormone effects on fMRI and cognitive measures of encoding: importance of hormone preparationC E Gleason
Section of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin, 2870 University Ave, Suite 106, Madison, WI 53705, USA
Neurology 67:2039-41. 2006..These preliminary findings emphasize the need to characterize differential neural effects of various HTs...
A preliminary study of the safety, feasibility and cognitive efficacy of soy isoflavone supplements in older men and womenCarey E Gleason
Section of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin, Madison, WI 53705, USA
Age Ageing 38:86-93. 2009..Unfortunately, few studies enrolled adults over the age of 70, and none included older men...
Awareness of memory abilities in community-dwelling older adults with suspected dementia and mild cognitive impairmentFeng Lin
School of Nursing, Department of Medicine, School of Medicine and Public Health, University of Wisconsin Madison, Madison, WI, USA
Dement Geriatr Cogn Disord 30:83-92. 2010....
Short-term hormone therapy with transdermal estradiol improves cognition for postmenopausal women with Alzheimer's disease: results of a randomized controlled trialWhitney Wharton
University of Wisconsin, School of Medicine and Public Health, William S Middleton Memorial VA Hospital, 2500 Overlook Terrace, GRECC11G Madison, WI 53705, USA
J Alzheimers Dis 26:495-505. 2011..Moreover, treatment-related changes in plasma estradiol were positively correlated with improvements in visual memory. Short-term HT that includes the use of estradiol has favorable effects on cognition in women with AD...
Magnetic resonance imaging characterization of brain structure and function in mild cognitive impairment: a reviewMichele L Ries
William S Middleton Memorial Veterans Hospital Geriatric Research Education and Clinical Center, Madison, Wisconsin 53705, USA
J Am Geriatr Soc 56:920-34. 2008..Third, we will make recommendations regarding the current clinical use of MRI in identification of MCI. As a conclusion, we will look to the future of neuroimaging as a tool in early AD detection...
Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimer's diseaseCynthia M Carlsson
Department of Medicine, Section of Geriatrics and Gerontology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA
J Alzheimers Dis 13:187-97. 2008..It is unclear if statins modify Abeta metabolism or improve cognition in asymptomatic middle-aged adults at increased risk for AD...
Cognitive benefits of hormone therapy: cardiovascular factors and healthy-user biasWhitney Wharton
School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705, USA
Maturitas 64:182-7. 2009..The present observational, community-based, case-controlled study examined the 'healthy-user' bias theory by comparing cognitive task performance in two groups of postmenopausal women, who were either HT users or non-users...
Effect of Alzheimer disease risk on brain function during self-appraisal in healthy middle-aged adultsSterling C Johnson
Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, 2500 Overlook Terrace, Madison, WI 53705, USA
Arch Gen Psychiatry 64:1163-71. 2007....
The effects of ramipril in individuals at risk for Alzheimer's disease: results of a pilot clinical trialWhitney Wharton
Alzheimer s Disease Research Center, University of Wisconsin, Madison, WI 53705, USA
J Alzheimers Dis 32:147-56. 2012....
Anosognosia in mild cognitive impairment: Relationship to activation of cortical midline structures involved in self-appraisalMichele L Ries
Geriatric Research Education and Clinical Center, William S Middleton VA Hospital, Madison, Wisconsin 53705, USA
J Int Neuropsychol Soc 13:450-61. 2007..This finding highlights the level of anosognosia in MCI as an important predictor of response to self-appraisal in cortical midline structures, brain regions vulnerable to changes in early AD...
A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E epsilon4 alleleRyan J Haasl
Section of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA
BMC Med Genet 9:37. 2008....
Standardized note template improves screening of firearm access and driving among veterans with dementiaNoelle K Loconte
Department of Medicine, Section of Hematology Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
Am J Alzheimers Dis Other Demen 23:313-8. 2008..001). In memory assessment clinic, 31.8% had firearms access and 50% were driving. Many patients continued to drive and have access to firearms. The use of templates for the progress note was effective in increasing the screening rate...
Midlife predictors of Alzheimer's diseaseB B Bendlin
William S Middleton Memorial Veterans Hospital, Geriatric Research Educational and Clinical Center, Madison, WI, USA
Maturitas 65:131-7. 2010..Here, we review midlife risk factors for AD, and address the potential for therapeutic intervention in midlife...
Activation of brain regions vulnerable to Alzheimer's disease: the effect of mild cognitive impairmentS C Johnson
Geriatric Research Education and Clinical Center, Wm S Middleton VA Hospital, 2500 Overlook Terrace 11G, GRECC, Madison, WI 53705, USA
Neurobiol Aging 27:1604-12. 2006..Our results suggest that a change in function in the PC may account, in part, for memory recollection failure in AD...
Estrogen and Alzheimer's disease: the story so farBrenna Cholerton
Geriatric Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle/Tacoma, Washington, USA
Drugs Aging 19:405-27. 2002..These important issues must be addressed in order to establish the role of estrogen for the prevention and treatment of AD in women...
Research Grants
- Alzheimer's Disease: Potential Benefit of IsoflavonesCarey Gleason; Fiscal Year: 2007..In addition, blood, collected at each treatment visit, will be assayed for plasma isoflavone levels, and other neuroendocrine markers of interest. ..
