Research Topics
| LAURENT GILLES GLANCESummaryAffiliation: University of Rochester Country: USA Publications
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Publications
Outcomes of adult trauma patients admitted to trauma centers in Pennsylvania, 2000-2009Laurent G Glance
Department of Anesthesiology, University of Rochester Medical Center, 601 Elmwood Ave, PO Box 604, Rochester, NY 14642, USA
Arch Surg 147:732-7. 2012..To examine longitudinal trends in mortality for injured patients admitted to trauma centers...
Impact of trauma center designation on outcomes: is there a difference between Level I and Level II trauma centers?Laurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, Rochester, NY 14642, USA
J Am Coll Surg 215:372-8. 2012..The objective of this study was to compare mortality and complications for injured patients admitted to Level I and Level II trauma centers...
The association between nurse staffing and hospital outcomes in injured patientsLaurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, Rochester, NY, USA
BMC Health Serv Res 12:247. 2012..The impact of nurse staffing and skill mix on trauma outcomes has not been previously reported. The goal of this study was to examine whether nurse staffing levels and nursing skill mix are associated with trauma patient outcomes...
The Surgical Mortality Probability Model: derivation and validation of a simple risk prediction rule for noncardiac surgeryLaurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, Rochester, NY 14642, USA
Ann Surg 255:696-702. 2012....
Association between trauma quality indicators and outcomes for injured patientsLaurent G Glance
Department of Anesthesiology, University of Rochester Medical Center, 601 Elmwood Ave, Box 604, Rochester, NY 14642, USA
Arch Surg 147:308-15. 2012..To examine the association between the American College of Surgeons Committee on Trauma (ACSCOT) quality indicators and outcomes...
The effect of preexisting conditions on hospital quality measurement for injured patientsLaurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, Rochester, NY 14642, USA
Ann Surg 251:728-34. 2010..To determine whether adjusting for comorbidities significantly affects hospital quality measurement compared with adjusting for injury severity alone...
TMPM-ICD9: a trauma mortality prediction model based on ICD-9-CM codesLaurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, Rochester, New York 14642, USA
Ann Surg 249:1032-9. 2009..To develop and validate a new ICD-9 injury model that uses regression modeling, as opposed to a simple ratio measurement, to estimate empiric injury severities for each of the injuries in the ICD-9-CM lexicon...
Expert consensus vs empirical estimation of injury severity: effect on quality measurement in traumaLaurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, 601 Elmwood Ave, Box 604, Rochester, NY 14642, USA
Arch Surg 144:326-32; discussion 332. 2009..To determine the extent to which the Injury Severity Score (ISS) and Trauma Mortality Probability Model (T-MPM), a new trauma injury score based on empirical injury severity estimates, agree on hospital quality...
Impact of statistical approaches for handling missing data on trauma center qualityLaurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, Rochester, NY 14642, USA
Ann Surg 249:143-8. 2009..To determine whether imputed data can be used to produce unbiased hospital quality measures...
Impact of date stamping on patient safety measurement in patients undergoing CABG: experience with the AHRQ Patient Safety IndicatorsLaurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
BMC Health Serv Res 8:176. 2008..The objective of this study is to examine whether the AHRQ PSIs accurately measure hospital complication rates, using the data with present-on-admission (POA) codes to distinguish between complications and pre-existing conditions..
Impact of the present-on-admission indicator on hospital quality measurement: experience with the Agency for Healthcare Research and Quality (AHRQ) Inpatient Quality IndicatorsLaurent G Glance
University of Rochester School of Medicine, Rochester, New York, USA
Med Care 46:112-9. 2008..The extent to which the lack of a POA indicator biases quality assessment based on the AHRQ mortality measures is unknown...
Effect of complications on mortality after coronary artery bypass grafting surgery: evidence from New York StateLaurent G Glance
University of Rochester School of Medicine, Rochester, NY, USA
J Thorac Cardiovasc Surg 134:53-8. 2007..Complications are associated with increased risk of death. The objective of this study is to quantify the increased odds of dying from complications after isolated coronary artery bypass grafting surgery...
Hospital performance in caring for injured patients: does the type of injury make a difference?Laurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, Rochester, New York 14642, USA
Arch Surg 144:1121-6. 2009..To determine whether quality measures based on injury-specific models provide a different perspective about relative hospital rankings compared with a single outcome measure based on all trauma patients...
The Survival Measurement and Reporting Trial for Trauma (SMARTT): background and study designLaurent G Glance
Department of Anesthesiology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 604, Rochester, NY 14642, USA
J Trauma 68:1491-7. 2010..The Survival Measurement and Reporting Trial for Trauma explores the feasibility of using the National Trauma Data Bank as a platform for measuring and improving trauma outcomes...
How well do hospital mortality rates reported in the New York State CABG report card predict subsequent hospital performance?Laurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, Rochester, NY 14642, USA
Med Care 48:466-71. 2010..The use of mortality report cards as the basis for hospital choice assumes that a hospital's current performance is predicted by its past performance...
The association between cost and quality in trauma: is greater spending associated with higher-quality care?Laurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, University of Rochester Medical Centre, Rochester, NY, USA
Ann Surg 252:217-22. 2010..To examine the association between trauma center quality and costs...
Perioperative outcomes among patients with the modified metabolic syndrome who are undergoing noncardiac surgeryLaurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, Rochester, New York, USA
Anesthesiology 113:859-72. 2010..This study will determine the impact of the modified metabolic syndrome (defined as the presence of obesity, hypertension, and diabetes) on perioperative outcomes...
Increases in mortality, length of stay, and cost associated with hospital-acquired infections in trauma patientsLaurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, Rochester, NY 14642, USA
Arch Surg 146:794-801. 2011..To explore the clinical impact and economic burden of hospital-acquired infections (HAIs) in trauma patients using a nationally representative database...
Variation in hospital complication rates and failure-to-rescue for trauma patientsLaurent G Glance
University of Rochester School of Medicine, NY, USA
Ann Surg 253:811-6. 2011..To examine whether failure-to-rescue is an important mechanism driving outcome differences across low- and high-mortality hospitals caring for trauma patients...
Relationship between Leapfrog Safe Practices Survey and outcomes in traumaLaurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, Rochester, NY 14642, USA
Arch Surg 146:1170-7. 2011..To examine the association between hospital self-reported compliance with the National Quality Forum patient safety practices and trauma outcomes in a nationally representative sample of level I and level II trauma centers...
Estimating the potential impact of regionalizing health care delivery based on volume standards versus risk-adjusted mortality rateLaurent G Glance
Department of Anesthesiology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 604, Rochester, NY 14642, USA
Int J Qual Health Care 19:195-202. 2007..To examine whether basing regionalization on risk-adjusted mortality would lead to better population outcomes than basing regionalization on procedure volume...
Effect of mortality rate on the performance of the Acute Physiology and Chronic Health Evaluation II: a simulation studyL G Glance
University of Rochester School of Medicine, NY, USA
Crit Care Med 28:3424-8. 2000..To evaluate the impact of case mix variation on the performance of the Acute Physiology and Chronic Health Evaluation (APACHE) II using measures of calibration and discrimination...
Comparing outcomes of coronary artery bypass surgery: Is the New York Cardiac Surgery Reporting System model sensitive to changes in case mix?L G Glance
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Crit Care Med 29:2090-6. 2001..To assess the validity of using the standardized mortality ratio (SMR), based on the New York State Cardiac Surgery Reporting System (CSRS) prediction model to compare coronary artery bypass grafting (CABG) outcomes between hospitals...
Is the hospital volume-mortality relationship in coronary artery bypass surgery the same for low-risk versus high-risk patients?Laurent G Glance
Department of Anesthesiology, University of Rochester Medical Center, School of Medicine and Dentistry, New York, Rochester 14642, USA
Ann Thorac Surg 76:1155-62. 2003..The objective of this study was to determine whether the volume-outcome association for CABG surgery is modified by patient risk...
Using hierarchical modeling to measure ICU qualityLaurent G Glance
University of Rochester, School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
Intensive Care Med 29:2223-9. 2003..To determine whether hierarchical modeling agrees with conventional logistic regression modeling on the identity of ICU quality outliers within a large multi-institutional database...
The relation between trauma center outcome and volume in the National Trauma DatabankLaurent G Glance
Department of Anesthesiology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 604, Rochester, New York 14642, USA
J Trauma 56:682-90. 2004..However, the evidence linking trauma center volume and outcome is not conclusive. The objective of this study was to examine the volume-mortality relation for patients with severe trauma in the National Trauma Databank...
Evaluating trauma center quality: does the choice of the severity-adjustment model make a difference?Laurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
J Trauma 58:1265-71. 2005..The primary trauma outcome prediction models used for evaluating the quality of trauma care, TRISS and ASCOT (A Severity Characterization of Trauma), were developed using the MTOS database...
The relation between surgeon volume and outcome following off-pump vs on-pump coronary artery bypass graft surgeryLaurent G Glance
University of Rochester School of Medicine, Rochester, NY, USA
Chest 128:829-37. 2005....
Impact of changing the statistical methodology on hospital and surgeon ranking: the case of the New York State cardiac surgery report cardLaurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Med Care 44:311-9. 2006..Risk adjustment is central to the generation of health outcome report cards. It is unclear, however, whether risk adjustment should be based on standard logistic regression, fixed-effects or random-effects modeling...
Use of a matching algorithm to evaluate hospital coronary artery bypass grafting performance as an alternative to conventional risk adjustmentLaurent G Glance
University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
Med Care 45:292-9. 2007..Although public reporting of hospital and physician performance is a cornerstone of the effort to improve health care quality, the optimal approach to risk adjustment is unknown...
Racial differences in the use of epidural analgesia for laborLaurent G Glance
University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Anesthesiology 106:19-25; discussion 6-8. 2007..There is strong evidence that pain is undertreated in black and Hispanic patients. The association between race and ethnicity and the use of epidural analgesia for labor is not well described...
Rating the quality of intensive care units: is it a function of the intensive care unit scoring system?Laurent G Glance
Department of Anaesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
Crit Care Med 30:1976-82. 2002..The objective of this study was to determine whether the identity of ICU quality outliers depends on the ICU scoring system used to calculate the standardized mortality ratio...
Identifying quality outliers in a large, multiple-institution database by using customized versions of the Simplified Acute Physiology Score II and the Mortality Probability Model II0Laurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
Crit Care Med 30:1995-2002. 2002..Seventeen of the 54 hospitals were categorized differently depending on which of the two scoring systems was used. Therefore, the rating of quality of care appears, in part, to be a function of the prediction model used...
Are high-quality cardiac surgeons less likely to operate on high-risk patients compared to low-quality surgeons? Evidence from New York StateLaurent G Glance
Department of Anesthesiology, University of Rochester Medical Center, 601 Elmwood Avenue, PO Box 604, Rochester, NY 14642, USA
Health Serv Res 43:300-12. 2008..It is unknown whether high-risk cardiac surgical patients have less access to high-quality surgeons compared with lower-risk patients...
A survey of the use of ultrasound during central venous catheterizationPeter L Bailey
Department of Anesthesiology, University of Rochester, Rochester, New York, USA
Anesth Analg 104:491-7. 2007..The use of ultrasound (US) during CVC has been recommended to improve patient safety. We performed a survey to evaluate the frequency of, and factors influencing, US use...
Judging trauma center quality: does it depend on the choice of outcomes?Laurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, New York 14642, USA
J Trauma 56:165-72. 2004..However, the use of survival as a measure of the effectiveness of trauma care may be too limited in scope because it fails to capture information regarding functional outcomes...
Does date stamping ICD-9-CM codes increase the value of clinical information in administrative data?Laurent G Glance
Department of Anesthesiology, University of Rochester Medical Center, Rochester, NY 14642, USA
Health Serv Res 41:231-51. 2006..The use of data fields that indicates whether each secondary diagnosis was present at the time of hospital admission may lead to the more accurate identification of preexisting conditions...
Accuracy of hospital report cards based on administrative dataLaurent G Glance
Department of Anesthesiology, University of Rochester School of Medicine, 601 Elmwood Avenue, Box 601, Rochester, NY 14642, USA
Health Serv Res 41:1413-37. 2006..However, the CPAA modifier will need to be further validated before date stamped administrative data can be used as the basis for health quality report cards...
The accuracy of the central landmark used for central venous catheterization of the internal jugular veinPeter L Bailey
Department of Anesthesiology, University of Rochester, Rochester, New York, USA
Anesth Analg 102:1327-32. 2006..The measured bias should be considered when the central landmark is used for central venous catheterization...
Gender differences in mortality in patients with severe sepsis or septic shockAnthony P Pietropaoli
Department of Medicine, University of Rochester Medical Center, Rochester, New York 14642, USA
Gend Med 7:422-37. 2010..Although the incidence of sepsis is higher in men than in women, it is controversial whether there are sex-based differences in sepsis-associated mortality...
Nurse working conditions and patient safety outcomesPatricia W Stone
Columbia University School of Nursing, New York, New York 10032, USA
Med Care 45:571-8. 2007..System approaches, such as improving working conditions, have been advocated to improve patient safety. However, the independent effect of many working condition variables on patient outcomes is unknown...
Mental illness and hospitalization for ambulatory care sensitive medical conditionsYue Li
Department of Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, USA
Med Care 46:1249-56. 2008..It is unknown whether patients with mental disorders have higher ACS admission rate, compared with patients without mental disorders...
Impact of patient volume on the mortality rate of adult intensive care unit patientsLaurent G Glance
University of Rochester School of Medicine and Dentistry, USA
Crit Care Med 34:1925-34. 2006..CONCLUSIONS: There is evidence that high ICU patient volumes are associated with lower mortality rates in high-risk critically ill adults...
Are patients with coexisting mental disorders more likely to receive CABG surgery from low-quality cardiac surgeons? The experience in New York StateYue Li
Department of Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 461 Grider Street, Buffalo, NY 14215, USA
Med Care 45:587-93. 2007..Presence of a mental disorder has been shown to be associated with reduced access to medical and surgical services. Little is known, however, about the relationship between mental disorders and the quality of medical/surgical care received...
Does risk adjustment of the CMS quality measures for nursing homes matter?Dana B Mukamel
University of California Irvine, Center for Health Policy Research, Irvine, California 92697 5800, USA
Med Care 46:532-41. 2008..The Centers for Medicare and Medicaid Services (CMS) publish a report card for nursing homes with 19 clinical quality measures (QMs). These measures include minimal risk adjustment...
Benchmarking in critical care: the road aheadLaurent G Glance
Chest 121:326-8. 2002
Improving the Glasgow Coma Scale score: motor score alone is a better predictorC Healey
Department of Surgery, University of Vermont, College of Medicine, Burlington 05401, USA
J Trauma 54:671-8; discussion 678-80. 2003..Because the m component is nonlinear in the log odds of survival, however, it should be mathematically transformed before its inclusion in broader outcome prediction models...
Coupling quality improvement with quality measurement in the intensive care unitLaurent G Glance
Crit Care Med 33:1144-6. 2005
Research Grants
- Are Volume Standards Accurate Measures of Quality?Laurent Glance; Fiscal Year: 2005..abstract_text> ..
- Improving Trauma Outcomes Using Hospital Performance ReportsLaurent Glance; Fiscal Year: 2007..Such a National Trauma Report Card could serve as a catalyst for improving short and long-term outcomes for trauma patients. ..
- Improving Trauma Outcomes Using Hospital Performance ReportsLAURENT GILLES GLANCE; Fiscal Year: 2010..Such a National Trauma Report Card could serve as a catalyst for improving short and long-term outcomes for trauma patients. ..
