Affiliation: University of Southern California
- Production of nitric oxide by mitochondriaC Giulivi
Department of Molecular Pharmacology and Toxicology, University of Southern California, Los Angeles, California 90033, USA
J Biol Chem 273:11038-43. 1998..This study demonstrates that mitochondria are a source of NO., the production of which may effect energy metabolism, O2 consumption, and O2 free radical formation...
- Iron primes hepatic macrophages for NF-kappaB activation in alcoholic liver injuryH Tsukamoto
Department of Medicine and Pathology, University of Southern California School of Medicine, Los Angeles 90033, California
Am J Physiol 277:G1240-50. 1999..These results support the pivotal role of heme-derived iron in priming HM for NF-kappaB activation and expression of proinflammatory genes in alcoholic liver injury...
- Functional implications of nitric oxide produced by mitochondria in mitochondrial metabolismC Giulivi
Department of Molecular Pharmacology and Toxicology, University of Southern California, 1985 Zonal Ave, Los Angeles, CA 90033, USA
Biochem J 332:673-9. 1998..This inhibition can be explained by the interaction of NO. with cytochrome oxidase at the binuclear centre. The role of NO. as a physiological modulator of cytochrome oxidase is discussed in terms of cellular metabolism...