Stephen E Gitelman
Affiliation: University of California
- Nephrogenic syndrome of inappropriate antidiuresis: a novel disorder in water balance in pediatric patientsStephen E Gitelman
Department of Pediatrics, Division of Pediatric Endocrinology, University of California at San Francisco, San Francisco, California 94143, USA
Am J Med 119:S54-8. 2006..including the following: (1) What is the frequency? (2) Are there nonrenal manifestations? (3) Are heterozygotes affected? (4) What is the optimal therapy? and (5) How do these mutations cause constitutive activation of the receptor?..
- Nephrogenic syndrome of inappropriate antidiuresisBrian J Feldman
Department of Pediatrics, Division of Endocrinology, University of California at San Francisco, San Francisco, CA 94143, USA
N Engl J Med 352:1884-90. 2005..These novel mutations cause constitutive activation of the receptor and are the likely cause of the patients' SIADH-like clinical picture, which we have termed "nephrogenic syndrome of inappropriate antidiuresis."..
- Oral urea for the treatment of chronic syndrome of inappropriate antidiuresis in childrenEric A Huang
Department of Pediatrics, Division of Endocrinology, University of California, San Francisco School of Medicine, USA
J Pediatr 148:128-31. 2006..Fluid intake was liberalized after serum sodium normalization. All four children normalized their serum sodium. No side effects or toxicities were experienced. Oral urea is a safe, effective treatment for chronic SIAD in children...
- Congenital hyperinsulinism in an infant caused by a macroscopic insulin-producing lesionAndrew A Bremer
Department of Pediatrics, Division of Endocrinology, University of California, San Francisco 94143 0434, USA
J Pediatr Endocrinol Metab 20:437-40. 2007..We describe a 1 month-old infant with severe congenital hyperinsulinism who had a macroscopic insulin-producing pancreatic lesion successfully treated with focal lesion enucleation...
- Increased incidence in post-transplant diabetes mellitus in children: a case-control analysisLouise C Greenspan
Division of Endocrinology, Department of Pediatrics, University of California, San Francisco, CA 94143 0434, USA
Pediatr Nephrol 17:1-5. 2002..We suggest that all children undergoing renal transplantation be screened routinely for PTDM after transplantation, and that such patients may benefit from the avoidance of tacrolimus, as it may cause permanent beta-cell injury...
- Prevalence and characteristics of type 2 diabetes mellitus in 9-18 year-old children with diabetic ketoacidosisAnil Sapru
Pediatric Critical Care Medicine, University of California, San Francisco, CA 94143, USA
J Pediatr Endocrinol Metab 18:865-72. 2005..To estimate the prevalence of type 2 diabetes mellitus (DM2) in 9-18 year-old children with diabetic ketoacidosis (DKA) and to describe the presenting biochemical characteristics and response to standardized DKA treatment...
- The effect of oral alpha-lipoic acid on oxidative stress in adolescents with type 1 diabetes mellitusEric A Huang
Division of Endocrinology, Department of Pediatrics, University of California, San Francisco School of Medicine, San Francisco, CA 94143 0434, USA
Pediatr Diabetes 9:69-73. 2008..Recently, an oral controlled-release formulation of alpha-lipoic acid (CRLA) was developed, and a pharmacokinetic study demonstrated that CRLA maintained significant plasma levels for 67% longer than a common quick-release formulation...
- Comparison of autoantibody-positive and autoantibody-negative pediatric participants enrolled in the T1D Exchange clinic registryAndrea Gerard-Gonzalez
University of California San Francisco, San Francisco, CA, USA
J Diabetes 5:216-23. 2013..To compare characteristics of autoantibody (aAb)-positive and -negative cases of type 1 diabetes (T1D) <18 years old in the T1D Exchange clinic registry...
- Persistent elevation of urine aquaporin-2 during water loading in a child with nephrogenic syndrome of inappropriate antidiuresis (NSIAD) caused by a R137L mutation in the V2 vasopressin receptorCLEMENT C CHEUNG
Department of Pediatrics, Division of Endocrinology, University of California, San Francisco, San Francisco, CA 94143
Int J Pediatr Endocrinol 2012:3. 2012..In addition, this is the first longitudinal report of a pediatric patient with NSIAD diagnosed in infancy who demonstrates the ability to maintain eunatremia during ad lib dietary intake...
- The use of a continuous glucose monitoring system in hypoglycemic disordersSusan C Conrad
Department of Pediatrics, University of California at San Francisco, San Francisco 94143, USA
J Pediatr Endocrinol Metab 17:281-8. 2004..To evaluate the use of a continuous glucose monitoring system (CGMS) in the evaluation and treatment of infants and children with hypoglycemic disorders...
- Nephrogenic syndrome of inappropriate antidiuresis (NSIAD): a paradigm for activating mutations causing endocrine dysfunctionStephen M Rosenthal
University of California, San Francisco
Pediatr Endocrinol Rev 4:66-70. 2006..The mechanisms by which these mutations constitutively activate the V2R are currently being investigated...
- A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetesKevan C Herold
Associate Professor of Medicine, Columbia University, PH10 105, 630 W 168th St, New York, NY 10032, USA
Diabetes 54:1763-9. 2005....
- Analysis of T-cell assays to measure autoimmune responses in subjects with type 1 diabetes: results of a blinded controlled studyVicki Seyfert-Margolis
Immune Teolerance Network, Bethesda, Maryland, USA
Diabetes 55:2588-94. 2006..They may be useful for assessment of cellular autoimmune responses involved in type 1 diabetes...
- Transition from multiple daily injections to continuous subcutaneous insulin infusion in type 1 diabetes mellitusSusan C Conrad
University of California, San Francisco 94143, USA
J Pediatr 140:235-40. 2002..To review our experience with insulin dosing during the conversion from multiple daily injections to continuous subcutaneous insulin infusion (CSII) for children and adolescents with type 1 diabetes mellitus...
- Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitusKevan C Herold
Naomi Berrie Diabetes Center and the Department of Medicine, Division of Endocrinology, College of Physicians and Surgeons, Columbia University, New York 10032, USA
N Engl J Med 346:1692-8. 2002..Preclinical studies suggested that a monoclonal antibody against CD3 could reverse hyperglycemia at presentation and induce tolerance to recurrent disease...
- A two-center randomized controlled feasibility trial of insulin pump therapy in young children with diabetesDarrell M Wilson
Division of Pediatric Endocrinology and Diabetes, Stanford University, Stanford, California 94305 5208, USA
Diabetes Care 28:15-9. 2005....