Research Topics
| Debbie S GipsonSummaryAffiliation: University of North Carolina Country: USA Publications
Research Grants
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Detail Information
Publications
Follow-up of phase I trial of adalimumab and rosiglitazone in FSGS: III. Report of the FONT study groupAlexandra Peyser
Department of Pediatrics, Division of Nephrology, Schneider Children s Hospital of North Shore LIJ Health System, 269 01 76th Avenue, New Hyde Park, NY 11040, USA
BMC Nephrol 11:2. 2010..Antifibrotic agents may slow or halt this process. We present outcomes of follow-up after a Phase I trial of adalimumab and rosiglitazone, antifibrotic drugs tested in the Novel Therapies in Resistant FSGS (FONT) study...
Renal transplantation in children with lupus nephritisDebbie S Gipson
Divisions of Nephrology and Hypertension and Rheumatology, University of North Carolina Chapel Hill, NC, USA
Am J Kidney Dis 41:455-63. 2003..This study was conducted to determine renal allograft and patient survival for children with lupus nephritis compared with pediatric allograft recipients with other causes of end-stage renal disease...
Therapeutic approach to FSGS in childrenDebbie S Gipson
Chapel Hill School of Medicine, University of North Carolina Kidney Center, University of North Carolina, 7012 Burnett Womack Hall, CB 7155, Chapel Hill, NC, 27599 7155, USA
Pediatr Nephrol 22:28-36. 2007..This educational article reviews the current therapeutic approach toward children with primary FSGS...- The central nervous system in childhood chronic kidney diseaseDebbie S Gipson
UNC Kidney Center, University of North Carolina School of Medicine, 7012 Burnett Womack Bldg, CB 7155, Chapel Hill, NC 27599 7155, USA
Pediatr Nephrol 22:1703-10. 2007..The paper concludes with suggestions for monitoring the neurodevelopmental status and pursuing appropriate early interventions for children with CKD... 
Management of childhood onset nephrotic syndromeDebbie S Gipson
Division of Nephrology and Hypertension, Department ofMedicine and Pediatrics, University of North Carolina, ChapelHill, North Carolina 27599 7155, USA
Pediatrics 124:747-57. 2009..The Children's Nephrotic Syndrome Consensus Conference was formed to systematically review the published literature and generate a children's primary nephrotic syndrome guideline for use in educational, therapeutic, and research venues...- Differential risk of remission and ESRD in childhood FSGSDebbie S Gipson
UNC Kidney Center, University of North Carolina, Chapel Hill, USA
Pediatr Nephrol 21:344-9. 2006..10, 95% CI 0.01-0.79, p =0.03). In summary, proteinuria remission status is a valid predictor of long-term renal survival in children with FSGS... - The nervous system and chronic kidney disease in childrenDebbie S Gipson
Division of Nephrology and Hypertension, University of North Carolina, 349 MacNider Hall, Campus Box 7155, NC 27599 7155, Chapel Hill, USA
Pediatr Nephrol 19:832-9. 2004..The paper concludes with suggestions for achieving progress in the understanding of this complication of kidney disease in children... - Neurocognitive functioning of children and adolescents with mild-to-moderate chronic kidney diseaseStephen R Hooper
Carolina Institute for Developmental Disabilities, CB 7255, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7255, USA
Clin J Am Soc Nephrol 6:1824-30. 2011..The primary objectives of this paper are (1) to determine the neurocognitive status in this population and (2) to identify sociodemographic and health-status variables associated with neurocognitive functioning... - Management patterns of childhood-onset nephrotic syndromeNathaniel Machardy
University of North Carolina at Chapel Hill, 27599 7155, USA
Pediatr Nephrol 24:2193-201. 2009..However, a systematic approach to patient care and improvement in health outcomes has been shown to substantially improve morbidity and mortality outcomes in children with chronic health conditions... - Predictors of relapse and end stage kidney disease in proliferative lupus nephritis: focus on children, adolescents, and young adultsKeisha L Gibson
Division of Nephrology and Hypertension, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7155, USA
Clin J Am Soc Nephrol 4:1962-7. 2009..Patterns and predictors of disease progression in a southeastern U.S. pediatric cohort with severe lupus nephritis are presented... - Brief report: intellectual and academic functioning in pediatric chronic kidney diseasePeter J Duquette
School of Education, University of North Carolina, Chapel Hill, NC 27599 7155, USA
J Pediatr Psychol 32:1011-7. 2007..Examine the intellectual and academic functioning in children with chronic kidney disease (CKD)... - Phase 1 trial of adalimumab in Focal Segmental Glomerulosclerosis (FSGS): II. Report of the FONT (Novel Therapies for Resistant FSGS) study groupMelanie S Joy
UNC Kidney Center and Division of Nephrology and Hypertension, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Am J Kidney Dis 55:50-60. 2010..Antifibrotic agents, such as tumor necrosis factor alpha antagonists, are a promising strategy to slow or halt the decline in renal function, based on preclinical and clinical data... - Phase I trial of rosiglitazone in FSGS: I. Report of the FONT Study GroupMelanie S Joy
University of North Carolina at Chapel Hill, University of North Carolina Kidney Center and Division of Nephrology and Hypertension, Chapel Hill, NC, USA
Clin J Am Soc Nephrol 4:39-47. 2009..The primary goal was assessment of safety, tolerability, and pharmacokinetics (PK) of rosiglitazone... - Obesity, albuminuria, and urinalysis findings in US young adults from the Add Health Wave III studyMaria Ferris
UNC Kidney Center and Division of Nephrology and Hypertension, CB 7155, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7156, USA
Clin J Am Soc Nephrol 2:1207-14. 2007..Obesity has been associated with kidney disease in adults. This study was designed to evaluate the association of obesity with an early marker of kidney disease, albuminuria, among young adults... - Memory and executive functions in pediatric chronic kidney diseaseDebbie S Gipson
Division of Pediatric Nephrology, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7155, USA
Child Neuropsychol 12:391-405. 2006..While pervasive dysfunction was not apparent in the children with CKD, they clearly appeared to be at risk for lower IQ as well as inefficiencies in key neurocognitive domains... - The differential effect of race among pediatric kidney transplant recipients with focal segmental glomerulosclerosisKui Huang
Division of Nephrology and Hypertension, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7155, USA
Am J Kidney Dis 43:1082-90. 2004..Children of nonblack races with FSGS have a worse allograft survival rate compared with other causes of ESRD. Within nonblack children with FSGS, living donor transplants convey a better allograft survival than cadaveric transplants... - A clinical tool to measure the components of health-care transition from pediatric care to adult care: the UNC TR(x)ANSITION scaleMaria E Ferris
UNC Kidney Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Ren Fail 34:744-53. 2012..To describe the development of the University of North Carolina (UNC) TR(x)ANSITION Scale that measures the health-care transition and self-management skills by youth with chronic health conditions... - Cognitive improvement in children with CKD after transplantPhil Icard
Center for Development and Learning, Carolina Institute for Developmental Disabilities, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7255, USA
Pediatr Transplant 14:887-90. 2010..In this regard, pediatric transplantation appears to have a positive impact on the intellectual and developmental functioning of children with CKD... - Trends in treatment and outcomes of survival of adolescents initiating end-stage renal disease care in the United States of AmericaMaria E Ferris
Division of Nephrology and Hypertension, University of NC Chapel Hill, Chapel Hill, NC, USA
Pediatr Nephrol 21:1020-6. 2006..The 80% 10-year survival rate for adolescent-onset ESRD is very good when compared with adult-onset ESRD. However, this represents a 30-fold increase in mortality compared to the general US adolescent population... - Social-behavioural functioning in paediatric chronic kidney diseaseS R Hooper
Department of Psychiatry, The Carolina Institute for Developmental Disabilities, University of North Carolina School of Medicine, Chapel Hill, NC, USA
Child Care Health Dev 35:832-40. 2009.... - Renal manifestations of systemic illness in childrenKeisha L Gibson
UNC Kidney Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Semin Nephrol 29:360-9. 2009..This article focuses on renal manifestations of systemic diseases such as vasculitis, drug- and infection-related tubulointerstitial injury, and thrombotic disorders... - A measure of success in kidney transplantationsDebbie S Gipson
Pediatr Transplant 8:104-5. 2004
Research Grants
- Multicenter Trial of Focal GlomerulosclerosisDebbie Gipson; Fiscal Year: 2007..The proposed case-control study will evaluate risk factors for the development of FSGS such as body mass, birth weight, viral illnesses and smoking in all patients screened for entry into the trial. ..