Research Topics
| Vicente GilsanzSummaryAffiliation: University of Southern California Country: USA Publications
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Detail Information
Publications
Fat mass is not beneficial to bone in adolescents and young adultsAgnieszka Janicka
Childrens Hospital Los Angeles, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 92:143-7. 2007..Although muscle mass is beneficial to bone, studies on the effect of fat mass on bone have yielded conflicting results...- Assessing bone mass in children and adolescentsTishya A L Wren
Childrens Hospital Los Angeles, Department of Radiology, MS 81, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA
Curr Osteoporos Rep 4:153-8. 2006..Further research is needed to relate these measures to osteoporosis in the elderly and to short-term and long-term fracture risk... - Assessment of bone acquisition in childhood and adolescenceVicente Gilsanz
Radiology Department, Childrens Hospital Los Angeles, Los Angeles, California 90027, USA
Pediatrics 119:S145-9. 2007.... 
Relevance of brown adipose tissue in infancy and adolescenceVicente Gilsanz
Department of Radiology, Children s Hospital Los Angeles, Los Angeles, CA, USA
Pediatr Res 73:3-9. 2013..In this review, we discuss the potential role of this tissue in regulating weight and musculoskeletal development in children...- The depiction of brown adipose tissue is related to disease status in pediatric patients with lymphomaVicente Gilsanz
Department of Radiology, Children s Hospital Los Angeles, Keck School of Medicine, CA 90027, USA
AJR Am J Roentgenol 198:909-13. 2012..The objective of our study was to determine whether the depiction of brown adipose tissue (BAT) in PET/CT studies of pediatric patients with lymphoma is related to disease status... 
Changes in brown adipose tissue in boys and girls during childhood and pubertyVicente Gilsanz
Department of Radiology, Children s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
J Pediatr 160:604-609.e1. 2012..To characterize the changes in brown adipose tissue (BAT) occurring during puberty in boys and girls...- Functional brown adipose tissue is related to muscle volume in children and adolescentsVicente Gilsanz
Department of Radiology, Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
J Pediatr 158:722-6. 2011..We examined whether the depiction of brown adipose tissue (BAT) with positron emission tomography/computed tomography (PET/CT) in pediatric patients is associated with anthropometric measures... - Low-level, high-frequency mechanical signals enhance musculoskeletal development of young women with low BMDVicente Gilsanz
Department of Radiology, Childrens Hospital of Los Angeles, University of Southern California, Keck School of Medicine, Los Angeles, California 90027, USA
J Bone Miner Res 21:1464-74. 2006..Twelve months of this noninvasive signal, induced as whole body vibration for at least 2 minutes each day, increased bone and muscle mass in the axial skeleton and lower extremities compared with controls... - Age at onset of puberty predicts bone mass in young adulthoodVicente Gilsanz
Children s Hospital Los Angeles, Department of Radiology, Los Angeles, CA 90027, USA
J Pediatr 158:100-5, 105.e1-2. 2011..To determine whether the commencement and length of puberty influences dual x-ray absorptiometry (DXA) values of bone mineral content (BMC) and bone mineral density (BMD) in the axial and appendicular skeleton at skeletal maturity... - Differential effect of gender on hepatic fatVicente Gilsanz
Department of Radiology, MS 81, Children s Hospital Los Angeles, USC, Keck School of Medicine, 4650 Sunset Blvd, Los Angeles, CA 90027, USA
Pediatr Radiol 41:1146-53. 2011..There are discrepant data on whether men or women have a higher risk for hepatic steatosis... - Reciprocal relations of subcutaneous and visceral fat to bone structure and strengthVicente Gilsanz
Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 94:3387-93. 2009..Increased body fat is a risk factor for cardiovascular and metabolic disease, yet it is uncertain whether obesity protects against osteoporosis or adiposity is harmful to bone... - Vitamin D status and its relation to muscle mass and muscle fat in young womenVicente Gilsanz
Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 95:1595-601. 2010..Vitamin D insufficiency has now reached epidemic proportions and has been linked to increased body fat and decreased muscle strength. Whether vitamin D insufficiency is also related to adipose tissue infiltration in muscle is not known... - Quantitative CT reference values for vertebral trabecular bone density in children and young adultsVicente Gilsanz
Department of Radiology, Childrens Hospital Los Angeles, 4650 Sunset Blvd, MS 81, Los Angeles, CA 90027, USA
Radiology 250:222-7. 2009..To determine normative reference values for vertebral trabecular bone density (TBD) obtained by using quantitative computed tomography (CT) in healthy white children, teenagers, and young adults of both sexes... - Bone acquisition in healthy young females is reciprocally related to marrow adiposityNatascia Di Iorgi
Department of Radiology, Childrens Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 95:2977-82. 2010..Considerable evidence indicates that osteoblasts and adipocytes share a common progenitor cell in the bone marrow that is capable of mutually exclusive differentiation into the cell lineages responsible for bone and fat formation... - Bone marrow fat is inversely related to cortical bone in young and old subjectsTishya A L Wren
Department of Radiology, Childrens Hospital Los Angeles, MS 81, 4650 Sunset Boulevard, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 96:782-6. 2011..Using magnetic resonance imaging, we examined whether the relation between the amount of marrow fat and cortical bone is present at multiple sites along the diaphyses of the long bones of young and old males and females... - Timing of peak bone mass: discrepancies between CT and DXATishya A L Wren
Children s Hospital Los Angeles, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 92:938-41. 2007..The time of life in which peak bone mass in the axial skeleton is attained has been the subject of considerable controversy, with estimates ranging from the time of sexual and skeletal maturity to the fifth decade of life... - Reciprocal relation between marrow adiposity and the amount of bone in the axial and appendicular skeleton of young adultsNatascia Di Iorgi
Department of Radiology, Children s Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA
J Clin Endocrinol Metab 93:2281-6. 2008..To address this question and avoid the confounding effect of bone loss, we examined teenagers and young adults... - Bone acquisition in healthy children and adolescents: comparisons of dual-energy x-ray absorptiometry and computed tomography measuresTishya A L Wren
Department of Orthopedics, MS#81, 4650 Sunset Boulevard, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 90:1925-8. 2005..Use of DXA BMD would be reasonable if adjustments for body size, pubertal status, and skeletal maturity are made, but these additional assessments add significant complexity to the studies... - Bone densitometry in pediatric populations: discrepancies in the diagnosis of osteoporosis by DXA and CTTishya A L Wren
Department of Radiology, Division of Orthopaedics, Children's Hospital Los Angeles, California, USA
J Pediatr 146:776-9. 2005.... - Adiposity predicts carotid intima-media thickness in healthy children and adolescentsSteven D Mittelman
Department of Pediatrics, Division of Endocrinology, Diabetes and Metabolism, Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
J Pediatr 156:592-7.e2. 2010.... - Bone density and size in ambulatory children with cerebral palsyTishya Al Wren
Children s Orthopaedic Center, Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
Dev Med Child Neurol 53:137-41. 2011..To examine the relation of axial and appendicular bone properties in ambulatory children with cerebral palsy (CP) to functional (Gross Motor Function Classification System [GMFCS]) level... - Racial disparity in fracture risk between white and nonwhite children in the United StatesTishya A L Wren
Departments of Orthopaedic Surgery and Radiology, Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
J Pediatr 161:1035-40. 2012..To examine risk factors for fracture in a racially diverse cohort of healthy children in the US... - Effect of high-frequency, low-magnitude vibration on bone and muscle in children with cerebral palsyTishya A L Wren
Childrens Orthopaedic Center, Childrens Hospital, Los Angeles, Los Angeles, CA 90027, USA
J Pediatr Orthop 30:732-8. 2010..The purpose of this study was to examine the effects of this intervention on bone and muscle in children with CP... - Inverse association between brown adipose tissue activation and white adipose tissue accumulation in successfully treated pediatric malignancyJames S Chalfant
Department of Radiology, Children s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Am J Clin Nutr 95:1144-9. 2012..Although the accumulation of white adipose tissue (WAT) is a risk factor for disease, brown adipose tissue (BAT) has been suggested to have a protective role against obesity... - Obesity and fat quantification in lean tissues using three-point Dixon MR imagingArzu Kovanlikaya
Department of Radiology, Children's Hospital of Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027, USA
Pediatr Radiol 35:601-7. 2005..74; P=0.001). SUMMARY: We conclude that in nondiabetic teenagers, obesity is associated with an increased accumulation of fat in the pancreas without impairment of insulin secretion... - Contribution of the vertebral posterior elements in anterior-posterior DXA spine scans in young subjectsDavid C Lee
Orthopaedic Center, Childrens Hospital, Los Angeles, California, USA
J Bone Miner Res 24:1398-403. 2009..We conclude that DXA BMC provides a measure of bone that is most consistent with QCT and that the contribution of the posterior elements is consistent in young subjects after sexual maturity... - Bone measures in HIV-1 infected children and adolescents: disparity between quantitative computed tomography and dual-energy X-ray absorptiometry measurementsPisit Pitukcheewanont
Division of Endocrinology, Department of Pediatrics, Children s Hospital Los Angeles, University of Southern California, Los Angeles, CA 90027, USA
Osteoporos Int 16:1393-6. 2005..In contrast, vertebral BD measurements by CT are normal. The lower bone measurements were primarily due to the decreased bone and body size of the HIV-1 subjects... - Limitations of peripheral quantitative computed tomography metaphyseal bone density measurementsDavid C Lee
Department of Biomedical Engineering, University of Southern California, Los Angeles, California 90089, USA
J Clin Endocrinol Metab 92:4248-53. 2007..Large variations in bone morphology associated with skeletal development may limit the interpretation of pediatric pQCT studies based on a single slice... - Effect of gender on intra-abdominal fat in teenagers and young adultsSandra A Chung
Department of Radiology, MS 81, Childrens Hospital Los Angeles, USC, Keck School of Medicine, 4650 Sunset Blvd, Los Angeles, CA 90027, USA
Pediatr Radiol 41:469-75. 2011..However, the time when this gender difference appears is a matter of controversy... - Low cortical bone density measured by computed tomography in children and adolescents with untreated hyperthyroidismNawaporn Numbenjapon
Center for Endocrinology, Diabetes and Metabolism, Department of Pediatrics, Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
J Pediatr 150:527-30. 2007..To determine whether increased thyroid hormones levels have an effect on various bone components (cortical vs cancellous bone)... - Brown adipose tissue and its relationship to bone structure in pediatric patientsSkorn Ponrartana
Department of Radiology, Viterbi School of Engineering, University of Southern California, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 97:2693-8. 2012..Emerging evidence suggests a possible link between brown adipose tissue (BAT) and bone metabolism... - Bone, muscle, and fat: sex-related differences in prepubertal childrenKiumars Arfai
Department of Radiology, Childrens Hospital Los Angeles, 4650 Sunset Blvd, Mail Stop 81, Los Angeles, CA 90027, USA
Radiology 224:338-44. 2002..CONCLUSION: Together, these data indicate that sex is an important determinant of the morphology in humans well before the beginning of puberty... - Reproducibility of carotid intima-media thickness measurements in young adultsJaime Gonzalez
Department of Radiology, Children s Hospital Los Angeles, MS No 81, 4650 Sunset Blvd, Los Angeles, CA 90027, USA
Radiology 247:465-71. 2008.... - Differential computed tomographic attenuation of metabolically active and inactive adipose tissues: preliminary findingsHouchun Harry Hu
Department of Radiology, Children s Hospital of Los Angeles, University of Southern California, Los Angeles, CA 90027, USA
J Comput Assist Tomogr 35:65-71. 2011..Hounsfield units of active brown fat were more positive (P < 0.001) than inactive fat (-62.4 ± 5.3 vs -86.7 ± 7.0) and the difference was observed in both males and females... - Aortic calcification and the risk of osteoporosis and fracturesEloy Schulz
Department of Radiology, MS 81, 4650 Sunset Boulevard, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 89:4246-53. 2004..Smaller, but highly significant differences were also found between all other quartiles. We conclude that aortic calcifications are a strong predictor for low bone density and fragility fractures... - Optimal monitoring time interval between DXA measures in childrenJohn A Shepherd
Department of Radiology, Bone and Breast Density Research Group, University of California, San Francisco, San Francisco, CA, USA
J Bone Miner Res 26:2745-52. 2011..MTI was neither useful nor stable in late adolescence and young adulthood. Alternative criteria to determine scan intervals must be used in this age range... - Pediatric DXA bone measurementsMonique M Sanchez
Department of Radiology, Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA
Pediatr Endocrinol Rev 2:337-41. 2005..This paper gives a brief overview of how DXA works, calibration issues, efficacy, safety, and test interpretation... - Fat quantification using three-point dixon technique: in vitro validationArzu Kovanlikaya
Department of Radiology at Childrens Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027, USA
Acad Radiol 12:636-9. 2005..To test the repeatability, reproducibility and accuracy of the three-point Dixon (3PD) sequence for estimating true fat volume ratios using a fat/water phantom... - Three-point technique of fat quantification of muscle tissue as a marker of disease progression in Duchenne muscular dystrophy: preliminary studyTishya A L Wren
Department of Radiology, Children s Hospital Los Angeles, 4650 Sunset Blvd, MS 81, Los Angeles, CA 90027, USA
AJR Am J Roentgenol 190:W8-12. 2008..The purpose of this study was to examine whether muscle lipid infiltration measured with the three-point Dixon MRI technique has value as a marker of disease severity... - Unequivocal identification of brown adipose tissue in a human infantHouchun H Hu
Department of Radiology, Children s Hospital of Los Angeles, Keck School of Medicine, University of Southern California Los Angeles, California, USA
J Magn Reson Imaging 35:938-42. 2012..Current findings suggest that BAT is present in significant amounts in children and that MRI and CT can differentiate BAT from WAT based on intrinsic tissue properties... - Quantitative computed tomography measurements of bone mineral density in prepubertal children with congenital hypothyroidism treated with L-thyroxinePisit Pitukcheewanont
Division of Endocrinology, Department of Pediatrics, Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
J Pediatr Endocrinol Metab 17:889-93. 2004..In pre-pubertal children with CH, LT4 appears to have no significant effect on BD. Moreover, absence or hypoplasia of the thyroid parenchyma appears to have no significant impact on bone formation within the first 10 years of life... - Premature carotid artery disease in pediatric cancer survivors treated with neck irradiationKathleen A Meeske
Department of Pediatrics, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA
Pediatr Blood Cancer 53:615-21. 2009..The purpose of this study is to determine if carotid disease is more prevalent among pediatric cancer survivors treated with neck irradiation than among healthy controls... - Characterization of human brown adipose tissue by chemical-shift water-fat MRIHouchun H Hu
Department of Radiology, Children s Hospital Los Angeles, 4650 Sunset Blvd, MS 81, Los Angeles, California 90027, USA
AJR Am J Roentgenol 200:177-83. 2013.... - Developments in the imaging of brown adipose tissue and its associations with muscle, puberty, and health in childrenHouchun H Hu
Departments of Radiology and Pediatrics, Children s Hospital of Los Angeles, Keck School of Medicine, University of Southern California Los Angeles, CA, USA
Front Endocrinol (Lausanne) 2:33. 2011.... - Quantitative computed tomography assessment of transfusional iron overloadJohn C Wood
Division of Paediatric Cardiology, Department of Paediatrics, Children s Hospital Los Angeles, CA 90027, USA
Br J Haematol 153:780-5. 2011.... - The state of pediatric bone: summary of the ASBMR pediatric bone initiativeGordon L Klein
University of Texas Medical Branch, Galveston, USA
J Bone Miner Res 20:2075-81. 2005 - The bone mineral density in childhood study: bone mineral content and density according to age, sex, and raceHeidi J Kalkwarf
Division of General and Community Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
J Clin Endocrinol Metab 92:2087-99. 2007..Low bone mass may increase risk of fracture. Several chronic medical conditions, medications, and lifestyle factors affect bone mineral accrual. Appropriate reference values are essential for identification of children with bone deficits... - Establishment of peak bone massStefano Mora
Laboratory of Pediatric Endocrinology, Scientific Institute H San Raffaele, Milan, Italy
Endocrinol Metab Clin North Am 32:39-63. 2003....