Affiliation: University of Southern California
- Bone density in children: a review of the available techniques and indicationsV Gilsanz
Radiology Department, Children s Hospital Los Angeles, CA 90027, USA
Eur J Radiol 26:177-82. 1998..However, ultrasound values are dependent on so many structural properties not yet fully understood, that it is difficult to use the information meaningfully in children...
- Differential effect of race on the axial and appendicular skeletons of childrenV Gilsanz
Department of Radiology, Childrens Hospital Los Angeles, California 90027, USA
J Clin Endocrinol Metab 83:1420-7. 1998..75% and 5.7% higher, respectively, in black children. Such significant variations may contribute to the racial differences in the prevalence of osteoporosis between black and white adults...
- Bone size and density measurements in prepubertal children with Turner syndrome prior to growth hormone therapyP Pitukcheewanont
Center for Endocrinology, Diabetes and Metabolism, Department of Pediatrics, University of Southern California, Los Angeles, CA 90027, USA
Osteoporos Int 22:1709-15. 2011..Using computed tomography (CT), we found the decreases in bone size of vertebrae and femur, cortical bone area (CBA) of femur and bone density (BD) of vertebrae in prepubertal female with Turner syndrome (TS) compared to those of controls...
- Increased body weight and decreased radial cross-sectional dimensions in girls with forearm fracturesD L Skaggs
Division of Orthopedic Surgery, Children's Hospital Los Angeles, California 90027, USA
J Bone Miner Res 16:1337-42. 2001..The smaller cross-sectional area confers a biomechanical disadvantage that, coupled with the greater body weight, increases the vulnerability to fracture after a fall...
- Digital hand atlas and web-based bone age assessment: system design and implementationF Cao
Department of Radiology, University of California, San Francisco 94143 0628, USA
Comput Med Imaging Graph 24:297-307. 2000..The digital atlas method based on open system Internet technology provides an alternative to supplement or replace the traditional one for a quantitative, accurate and cost-effective assessment of bone age...
- Skeletal age determinations in children of European and African descent: applicability of the Greulich and Pyle standardsS Mora
Department of Radiology, Childrens Hospital Los Angeles, University of Southern California, Keck's School of Medicine, Los Angeles, CA 90027, USA
Pediatr Res 50:624-8. 2001..New standards are needed to make clinical decisions that require reliable bone ages and to accurately represent a multiethnic pediatric population...
- Differential effect of marrow adiposity and visceral and subcutaneous fat on cardiovascular risk in young, healthy adultsN Di Iorgi
Department of Radiology, Childrens Hospital, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
Int J Obes (Lond) 32:1854-60. 2008..While the negative associations between visceral fat (VF) or subcutaneous fat (SF) and cardiovascular disease (CVD) risks are well known, the relation between marrow fat (MF) and metabolic risk is unexplored...
- Evaluation of the effects of oxandrolone on malnourished HIV-positive pediatric patientsS Fox-Wheeler
Divisions of Clinical Immunology and Allergy, Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
Pediatrics 104:e73. 1999..The anabolic steroid, oxandrolone, was evaluated because of its safe and effective use in other pediatric conditions...
- Increased carotid artery intima-media thickness following venoarterial extracorporeal membrane oxygenation in the neonatal periodP Friedlich
Division of Newborn and Infant Critical Care, Department of Pediatrics, Center for Fetal and Neonatal Medicine, Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, CA 90027, USA
J Perinatol 28:811-4. 2008..To compare left carotid intima-media thickness (CIMT) and biochemical markers for atherogenesis in neonatal venoarterial extracorporeal membrane oxygenation (ECMO) survivors with normal controls during childhood...
- Assessing bone mass in children and adolescentsTishya A L Wren
Childrens Hospital Los Angeles, Department of Radiology, MS 81, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA
Curr Osteoporos Rep 4:153-8. 2006..Further research is needed to relate these measures to osteoporosis in the elderly and to short-term and long-term fracture risk...
- Timing of peak bone mass: discrepancies between CT and DXATishya A L Wren
Children s Hospital Los Angeles, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 92:938-41. 2007..The time of life in which peak bone mass in the axial skeleton is attained has been the subject of considerable controversy, with estimates ranging from the time of sexual and skeletal maturity to the fifth decade of life...
- The bone mineral density in childhood study: bone mineral content and density according to age, sex, and raceHeidi J Kalkwarf
Division of General and Community Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
J Clin Endocrinol Metab 92:2087-99. 2007..Low bone mass may increase risk of fracture. Several chronic medical conditions, medications, and lifestyle factors affect bone mineral accrual. Appropriate reference values are essential for identification of children with bone deficits...
- Assessment of bone acquisition in childhood and adolescenceVicente Gilsanz
Radiology Department, Childrens Hospital Los Angeles, Los Angeles, California 90027, USA
Pediatrics 119:S145-9. 2007....
- Low cortical bone density measured by computed tomography in children and adolescents with untreated hyperthyroidismNawaporn Numbenjapon
Center for Endocrinology, Diabetes and Metabolism, Department of Pediatrics, Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
J Pediatr 150:527-30. 2007..To determine whether increased thyroid hormones levels have an effect on various bone components (cortical vs cancellous bone)...
- Limitations of peripheral quantitative computed tomography metaphyseal bone density measurementsDavid C Lee
Department of Biomedical Engineering, University of Southern California, Los Angeles, California 90089, USA
J Clin Endocrinol Metab 92:4248-53. 2007..Large variations in bone morphology associated with skeletal development may limit the interpretation of pediatric pQCT studies based on a single slice...
- Reciprocal relation between marrow adiposity and the amount of bone in the axial and appendicular skeleton of young adultsNatascia Di Iorgi
Department of Radiology, Children s Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA
J Clin Endocrinol Metab 93:2281-6. 2008..To address this question and avoid the confounding effect of bone loss, we examined teenagers and young adults...
- Fat mass is not beneficial to bone in adolescents and young adultsAgnieszka Janicka
Childrens Hospital Los Angeles, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 92:143-7. 2007..Although muscle mass is beneficial to bone, studies on the effect of fat mass on bone have yielded conflicting results...
- Low-level, high-frequency mechanical signals enhance musculoskeletal development of young women with low BMDVicente Gilsanz
Department of Radiology, Childrens Hospital of Los Angeles, University of Southern California, Keck School of Medicine, Los Angeles, California 90027, USA
J Bone Miner Res 21:1464-74. 2006..Twelve months of this noninvasive signal, induced as whole body vibration for at least 2 minutes each day, increased bone and muscle mass in the axial skeleton and lower extremities compared with controls...
- Pediatric DXA bone measurementsMonique M Sanchez
Department of Radiology, Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA
Pediatr Endocrinol Rev 2:337-41. 2005..This paper gives a brief overview of how DXA works, calibration issues, efficacy, safety, and test interpretation...
- Bone, muscle, and fat: sex-related differences in prepubertal childrenKiumars Arfai
Department of Radiology, Childrens Hospital Los Angeles, 4650 Sunset Blvd, Mail Stop 81, Los Angeles, CA 90027, USA
Radiology 224:338-44. 2002..To determine whether there are sex-related differences in vertebral cross-sectional dimensions, in paraspinous muscle area, and in the amount of fat in the subcutaneous and visceral compartments of prepubertal boys and girls...
- Establishment of peak bone massStefano Mora
Laboratory of Pediatric Endocrinology, Scientific Institute H San Raffaele, Milan, Italy
Endocrinol Metab Clin North Am 32:39-63. 2003....
- Quantitative computed tomography measurements of bone mineral density in prepubertal children with congenital hypothyroidism treated with L-thyroxinePisit Pitukcheewanont
Division of Endocrinology, Department of Pediatrics, Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
J Pediatr Endocrinol Metab 17:889-93. 2004..In pre-pubertal children with CH, LT4 appears to have no significant effect on BD. Moreover, absence or hypoplasia of the thyroid parenchyma appears to have no significant impact on bone formation within the first 10 years of life...
- Aortic calcification and the risk of osteoporosis and fracturesEloy Schulz
Department of Radiology, MS 81, 4650 Sunset Boulevard, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 89:4246-53. 2004..Smaller, but highly significant differences were also found between all other quartiles. We conclude that aortic calcifications are a strong predictor for low bone density and fragility fractures...
- Bone acquisition in healthy children and adolescents: comparisons of dual-energy x-ray absorptiometry and computed tomography measuresTishya A L Wren
Department of Orthopedics, MS 81, 4650 Sunset Boulevard, Los Angeles, California 90027, USA
J Clin Endocrinol Metab 90:1925-8. 2005..Use of DXA BMD would be reasonable if adjustments for body size, pubertal status, and skeletal maturity are made, but these additional assessments add significant complexity to the studies...
- Bone measures in HIV-1 infected children and adolescents: disparity between quantitative computed tomography and dual-energy X-ray absorptiometry measurementsPisit Pitukcheewanont
Division of Endocrinology, Department of Pediatrics, Children s Hospital Los Angeles, University of Southern California, Los Angeles, CA 90027, USA
Osteoporos Int 16:1393-6. 2005..In contrast, vertebral BD measurements by CT are normal. The lower bone measurements were primarily due to the decreased bone and body size of the HIV-1 subjects...
- Fat quantification using three-point dixon technique: in vitro validationArzu Kovanlikaya
Department of Radiology at Childrens Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027, USA
Acad Radiol 12:636-9. 2005..To test the repeatability, reproducibility and accuracy of the three-point Dixon (3PD) sequence for estimating true fat volume ratios using a fat/water phantom...
- Bone densitometry in pediatric populations: discrepancies in the diagnosis of osteoporosis by DXA and CTTishya A L Wren
Department of Radiology, Division of Orthopaedics, Children s Hospital Los Angeles, California, USA
J Pediatr 146:776-9. 2005..This study compared bone density values obtained by DXA with those from computed tomography (CT), which is not influenced by body or skeletal size...
- The state of pediatric bone: summary of the ASBMR pediatric bone initiativeGordon L Klein
University of Texas Medical Branch, Galveston, USA
J Bone Miner Res 20:2075-81. 2005
- Three-point technique of fat quantification of muscle tissue as a marker of disease progression in Duchenne muscular dystrophy: preliminary studyTishya A L Wren
Department of Radiology, Children s Hospital Los Angeles, 4650 Sunset Blvd, MS 81, Los Angeles, CA 90027, USA
AJR Am J Roentgenol 190:W8-12. 2008..The purpose of this study was to examine whether muscle lipid infiltration measured with the three-point Dixon MRI technique has value as a marker of disease severity...
- Reproducibility of carotid intima-media thickness measurements in young adultsJaime Gonzalez
Department of Radiology, Children s Hospital Los Angeles, MS No 81, 4650 Sunset Blvd, Los Angeles, CA 90027, USA
Radiology 247:465-71. 2008....
- Obesity and fat quantification in lean tissues using three-point Dixon MR imagingArzu Kovanlikaya
Department of Radiology, Children s Hospital of Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027, USA
Pediatr Radiol 35:601-7. 2005..It has been suggested that increased hepatic and intramuscular fat is associated with insulin resistance, and that increased pancreatic fat is related to impaired insulin secretion...